Published in Toxicol In Vitro on July 21, 2011
Intestinal toxicity evaluation of TiO2 degraded surface-treated nanoparticles: a combined physico-chemical and toxicogenomics approach in caco-2 cells. Part Fibre Toxicol (2012) 1.21
The effects of nanomaterials as endocrine disruptors. Int J Mol Sci (2013) 0.90
DNA damage in human skin keratinocytes caused by multiwalled carbon nanotubes with carboxylate functionalization. Toxicol Ind Health (2012) 0.85
Limitations of the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay when compared to three commonly used cell enumeration assays. BMC Res Notes (2015) 0.82
Natural mineral particles are cytotoxic to rainbow trout gill epithelial cells in vitro. PLoS One (2014) 0.78
Synthesis and anticancer activity of new flavonoid analogs and inconsistencies in assays related to proliferation and viability measurements. Int J Oncol (2014) 0.78
Mitochondrial dysfunction and loss of glutamate uptake in primary astrocytes exposed to titanium dioxide nanoparticles. Nanoscale (2015) 0.77
Interferences in the Optimization of the MTT Assay for Viability Estimation of Proteus mirabilis. Avicenna J Med Biotechnol (2015) 0.77
The importance of a validated standard methodology to define in vitro toxicity of nano-TiO2. Protoplasma (2011) 0.76
The Effect of Commonly Used Excipients on the Epithelial Integrity of Human Cervicovaginal Tissue. AIDS Res Hum Retroviruses (2016) 0.75
LDH, proliferation curves and cell cycle analysis are the most suitable assays to identify and characterize new phytotherapeutic compounds. Cytotechnology (2016) 0.75
Shape and surface properties of titanate nanomaterials influence differential cellular uptake behavior and biological responses in THP-1 cells. Biochem Biophys Rep (2017) 0.75
Mutational inactivation of STAG2 causes aneuploidy in human cancer. Science (2011) 5.04
PP2A is required for centromeric localization of Sgo1 and proper chromosome segregation. Dev Cell (2006) 3.88
The spindle checkpoint, aneuploidy, and cancer. Oncogene (2004) 3.61
Self-regulated Plk1 recruitment to kinetochores by the Plk1-PBIP1 interaction is critical for proper chromosome segregation. Mol Cell (2006) 3.38
The Mad2 spindle checkpoint protein undergoes similar major conformational changes upon binding to either Mad1 or Cdc20. Mol Cell (2002) 3.24
The SMC5/6 complex maintains telomere length in ALT cancer cells through SUMOylation of telomere-binding proteins. Nat Struct Mol Biol (2007) 3.15
The Mad2 spindle checkpoint protein has two distinct natively folded states. Nat Struct Mol Biol (2004) 2.87
SIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activity. Cancer Cell (2011) 2.73
Phosphorylation of Cdc20 by Bub1 provides a catalytic mechanism for APC/C inhibition by the spindle checkpoint. Mol Cell (2004) 2.66
Mechanistic insight into the allosteric activation of a ubiquitin-conjugating enzyme by RING-type ubiquitin ligases. Proc Natl Acad Sci U S A (2005) 2.60
Conformation-specific binding of p31(comet) antagonizes the function of Mad2 in the spindle checkpoint. EMBO J (2004) 2.57
Human Bub1 protects centromeric sister-chromatid cohesion through Shugoshin during mitosis. Proc Natl Acad Sci U S A (2004) 2.52
Structural basis for CoREST-dependent demethylation of nucleosomes by the human LSD1 histone demethylase. Mol Cell (2006) 2.32
Human MMS21/NSE2 is a SUMO ligase required for DNA repair. Mol Cell Biol (2005) 2.31
ATP binding and ATP hydrolysis play distinct roles in the function of 26S proteasome. Mol Cell (2006) 2.26
p31comet blocks Mad2 activation through structural mimicry. Cell (2007) 2.26
Human SMC5/6 complex promotes sister chromatid homologous recombination by recruiting the SMC1/3 cohesin complex to double-strand breaks. EMBO J (2006) 2.13
Nucleoporin levels regulate cell cycle progression and phase-specific gene expression. Dev Cell (2008) 2.00
FWD1-mediated degradation of FREQUENCY in Neurospora establishes a conserved mechanism for circadian clock regulation. EMBO J (2003) 1.89
Identification of two novel components of the human NDC80 kinetochore complex. J Biol Chem (2003) 1.89
Protein metamorphosis: the two-state behavior of Mad2. Structure (2008) 1.83
Phospho-H2A and cohesin specify distinct tension-regulated Sgo1 pools at kinetochores and inner centromeres. Curr Biol (2013) 1.69
Phosphorylation- and polo-box-dependent binding of Plk1 to Bub1 is required for the kinetochore localization of Plk1. Mol Biol Cell (2006) 1.68
Tracking spindle checkpoint signals from kinetochores to APC/C. Trends Biochem Sci (2013) 1.66
A requirement for breast-cancer-associated gene 1 (BRCA1) in the spindle checkpoint. Proc Natl Acad Sci U S A (2004) 1.63
Systematic identification and analysis of mammalian small ubiquitin-like modifier substrates. J Biol Chem (2004) 1.63
Structural basis of histone demethylation by LSD1 revealed by suicide inactivation. Nat Struct Mol Biol (2007) 1.59
Adsorption of ionizable organic contaminants on multi-walled carbon nanotubes with different oxygen contents. J Hazard Mater (2010) 1.45
Structural insights into histone lysine demethylation. Curr Opin Struct Biol (2010) 1.44
Structural basis for the inhibition of the LSD1 histone demethylase by the antidepressant trans-2-phenylcyclopropylamine. Biochemistry (2007) 1.44
Insights into mad2 regulation in the spindle checkpoint revealed by the crystal structure of the symmetric mad2 dimer. PLoS Biol (2008) 1.41
Autophosphorylation-dependent activation of human Mps1 is required for the spindle checkpoint. Proc Natl Acad Sci U S A (2007) 1.39
K-ras oncogene DNA sequences in pink salmon in streams impacted by the Exxon Valdez oil spill: no evidence of oil-induced heritable mutations. Ecotoxicology (2002) 1.39
Gold nanoparticle based label-free SERS probe for ultrasensitive and selective detection of trinitrotoluene. J Am Chem Soc (2009) 1.38
Phosphorylation-enabled binding of SGO1-PP2A to cohesin protects sororin and centromeric cohesion during mitosis. Nat Cell Biol (2012) 1.38
Structure of human Mad1 C-terminal domain reveals its involvement in kinetochore targeting. Proc Natl Acad Sci U S A (2012) 1.37
Two distinct pathways for inhibiting pds1 ubiquitination in response to DNA damage. J Biol Chem (2003) 1.35
Structure and substrate recruitment of the human spindle checkpoint kinase Bub1. Mol Cell (2008) 1.32
The Smc complexes in DNA damage response. Cell Biosci (2012) 1.31
Structural analysis of human Cdc20 supports multisite degron recognition by APC/C. Proc Natl Acad Sci U S A (2012) 1.31
Functional analysis of the spindle-checkpoint proteins using an in vitro ubiquitination assay. Methods Mol Biol (2004) 1.30
Gold nano-popcorn-based targeted diagnosis, nanotherapy treatment, and in situ monitoring of photothermal therapy response of prostate cancer cells using surface-enhanced Raman spectroscopy. J Am Chem Soc (2010) 1.30
Mutual regulation between the spindle checkpoint and APC/C. Semin Cell Dev Biol (2011) 1.29
Selective detection of mercury (II) ion using nonlinear optical properties of gold nanoparticles. J Am Chem Soc (2008) 1.29
Photomutagenicity of 16 polycyclic aromatic hydrocarbons from the US EPA priority pollutant list. Mutat Res (2004) 1.28
HTLV-I Tax directly binds the Cdc20-associated anaphase-promoting complex and activates it ahead of schedule. Proc Natl Acad Sci U S A (2004) 1.23
A perfluoroaryl-cysteine S(N)Ar chemistry approach to unprotected peptide stapling. J Am Chem Soc (2013) 1.23
Toxicity and environmental risks of nanomaterials: challenges and future needs. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev (2009) 1.22
KEN-box-dependent degradation of the Bub1 spindle checkpoint kinase by the anaphase-promoting complex/cyclosome. J Biol Chem (2006) 1.21
Challenge in Understanding Size and Shape Dependent Toxicity of Gold Nanomaterials in Human Skin Keratinocytes. Chem Phys Lett (2008) 1.21
Mechanistic analysis of a suicide inactivator of histone demethylase LSD1. Biochemistry (2007) 1.20
Multifunctional oval-shaped gold-nanoparticle-based selective detection of breast cancer cells using simple colorimetric and highly sensitive two-photon scattering assay. ACS Nano (2010) 1.17
Defining pathways of spindle checkpoint silencing: functional redundancy between Cdc20 ubiquitination and p31(comet). Mol Biol Cell (2011) 1.15
Crm1-mediated nuclear export of Cdc14 is required for the completion of cytokinesis in budding yeast. Cell Cycle (2005) 1.13
PICH and BLM limit histone association with anaphase centromeric DNA threads and promote their resolution. EMBO J (2011) 1.11
Phosphorylation-facilitated sumoylation of MEF2C negatively regulates its transcriptional activity. BMC Biochem (2006) 1.10
Kinase signaling in the spindle checkpoint. J Biol Chem (2009) 1.09
Mitotic centromeric targeting of HP1 and its binding to Sgo1 are dispensable for sister-chromatid cohesion in human cells. Mol Biol Cell (2011) 1.09
Effect of Surface Coating on the Toxicity of Silver Nanomaterials on Human Skin Keratinocytes. Chem Phys Lett (2010) 1.07
A novel motif governs APC-dependent degradation of Drosophila ORC1 in vivo. Genes Dev (2005) 1.07
Chloridodiphen-yl{[1-(1,3-thia-zol-2-yl-κN)ethyl-idene]-4-phenyl-thio-semicarbazidato-κN,S}tin(IV) methanol monosolvate. Acta Crystallogr Sect E Struct Rep Online (2011) 1.07
ZNF198 stabilizes the LSD1-CoREST-HDAC1 complex on chromatin through its MYM-type zinc fingers. PLoS One (2008) 1.06
Phosphorylation of the spindle checkpoint protein Mad2 regulates its conformational transition. Proc Natl Acad Sci U S A (2010) 1.04
Scc1 sumoylation by Mms21 promotes sister chromatid recombination through counteracting Wapl. Genes Dev (2012) 1.02
UVA light-induced DNA cleavage by isomeric methylbenz[a]anthracenes. Chem Res Toxicol (2002) 1.02
A study of the mechanism of in vitro cytotoxicity of metal oxide nanoparticles using catfish primary hepatocytes and human HepG2 cells. Sci Total Environ (2011) 1.00
A targeted health risk assessment following the Deepwater Horizon oil spill: polycyclic aromatic hydrocarbon exposure in Vietnamese-American shrimp consumers. Environ Health Perspect (2014) 1.00
Rapid colorimetric identification and targeted photothermal lysis of Salmonella bacteria by using bioconjugated oval-shaped gold nanoparticles. Chemistry (2010) 1.00
Multiple anaphase-promoting complex/cyclosome degrons mediate the degradation of human Sgo1. J Biol Chem (2008) 0.98
Photoirradiation of representative polycyclic aromatic hydrocarbons and twelve isomeric methylbenz[a]anthracene with UVA light: formation of lipid peroxidation. Toxicol Ind Health (2006) 0.98
Photomutagenicity of cosmetic ingredient chemicals azulene and guaiazulene. Mutat Res (2003) 0.98
Seven-coordinate anion complex with a tren-based urea: binding discrepancy of hydrogen sulfate in solid and solution states. Org Biomol Chem (2011) 0.97
Structure of the human cohesin inhibitor Wapl. Proc Natl Acad Sci U S A (2013) 0.95
Degradation of origin recognition complex large subunit by the anaphase-promoting complex in Drosophila. EMBO J (2003) 0.95
Single nucleotide polymorphisms of the DNA repair gene XPD/ERCC2 alter mRNA expression. Pharmacogenet Genomics (2007) 0.94
Phototoxicity and environmental transformation of polycyclic aromatic hydrocarbons (PAHs)-light-induced reactive oxygen species, lipid peroxidation, and DNA damage. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev (2012) 0.93
Integrating plasmonic nanoparticles with TiO₂ photonic crystal for enhancement of visible-light-driven photocatalysis. Environ Sci Technol (2012) 0.92
The L84F and the I143V polymorphisms in the O6-methylguanine-DNA-methyltransferase (MGMT) gene increase human sensitivity to the genotoxic effects of the tobacco-specific nitrosamine carcinogen NNK. Pharmacogenet Genomics (2005) 0.91
Natural product Celastrol destabilizes tubulin heterodimer and facilitates mitotic cell death triggered by microtubule-targeting anti-cancer drugs. PLoS One (2010) 0.90
Arsenic-induced genotoxic and cytotoxic effects in human keratinocytes, melanocytes and dendritic cells. Int J Environ Res Public Health (2004) 0.90
Iodido{4-phenyl-1-[1-(1,3-thia-zol-2-yl-κN)ethyl-idene]thio-semicarbazidato-κN',S}{4-phenyl-1-[1-(1,3-thia-zol-2-yl)ethyl-idene]thio-semicarbazide-κS}mercury(II). Acta Crystallogr Sect E Struct Rep Online (2011) 0.90
Kinetic and mechanistic studies of a cell cycle protein phosphatase Cdc14. J Biol Chem (2004) 0.90
Light-induced cytotoxicity of 16 polycyclic aromatic hydrocarbons on the US EPA priority pollutant list in human skin HaCaT keratinocytes: relationship between phototoxicity and excited state properties. Environ Toxicol (2007) 0.89
Phototoxicity and DNA damage induced by the cosmetic ingredient chemical azulene in human Jurkat T-cells. Mutat Res (2004) 0.89
Pharmacologic abrogation of the mitotic spindle checkpoint by an indolocarbazole discovered by cellular screening efficiently kills cancer cells. Cancer Res (2009) 0.89
Distinguishing "looped-out" and "stacked-in" DNA bulge conformation using fluorescent 2-aminopurine replacing a purine base. J Biomol Struct Dyn (2002) 0.88
Photodecomposition and phototoxicity of natural retinoids. Int J Environ Res Public Health (2005) 0.88
Running on a treadmill: dynamic inhibition of APC/C by the spindle checkpoint. Cell Div (2007) 0.87
Synthesis and photoirradiation of isomeric ethylchrysenes by UVA light leading to lipid peroxidation. Int J Environ Res Public Health (2007) 0.87
Highly sensitive and selective dynamic light-scattering assay for TNT detection using p-ATP attached gold nanoparticle. ACS Appl Mater Interfaces (2010) 0.86
Quality assurance and safety of herbal dietary supplements. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev (2009) 0.86
Light-induced mutagenicity in Salmonella TA102 and genotoxicity/cytotoxicity in human T-cells by 3,3'-dichlorobenzidine: a chemical used in the manufacture of dyes and pigments and in tattoo inks. Toxicology (2005) 0.86
Photocatalytic oxidation of aqueous ammonia using atomic single layer graphitic-C3N4. Environ Sci Technol (2014) 0.85
Regulation of CDC14: pathways and checkpoints of mitotic exit. Front Biosci (2003) 0.85
Toxic effects of gold nanoparticles on Salmonella typhimurium bacteria. Toxicol Ind Health (2011) 0.85
DNA damage and repair of human skin keratinocytes concurrently exposed to pyrene derivatives and UVA light. Toxicol Res (Camb) (2013) 0.85
Toxicity of kava kava. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev (2008) 0.84
A CpG oligodeoxynucleotide acts as a potent adjuvant for inactivated rabies virus vaccine. Vaccine (2008) 0.84
Part 3. Assessment of genotoxicity and oxidative damage in rats after chronic exposure to new-technology diesel exhaust in the ACES bioassay. Res Rep Health Eff Inst (2015) 0.84
Basic apoptotic and necrotic cell death in human liver carcinoma (HepG2 ) cells induced by synthetic azamacrocycle. Environ Toxicol (2012) 0.83