Published in Mol Cell on August 04, 2006
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Expanding the druggable space of the LSD1/CoREST epigenetic target: new potential binding regions for drug-like molecules, peptides, protein partners, and chromatin. PLoS Comput Biol (2013) 0.78
Molecular dynamics simulations indicate an induced-fit mechanism for LSD1/CoREST-H3-histone molecular recognition. BMC Biophys (2013) 0.78
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A rationally-designed chimeric KDM1A/KDM1B histone demethylase tower domain deletion mutant retaining enzymatic activity. FEBS Lett (2015) 0.76
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Yin-yang actions of histone methylation regulatory complexes in the brain. Epigenomics (2016) 0.75
Structure and function of dioxygenases in histone demethylation and DNA/RNA demethylation. IUCrJ (2014) 0.75
LHX2 Interacts with the NuRD Complex and Regulates Cortical Neuron Subtype Determinants Fezf2 and Sox11. J Neurosci (2017) 0.75
Oligomeric form of CtBP coactivates NeuroD1-mediated transcription. FEBS Lett (2016) 0.75
Towards the development of activity-based probes for detection of lysine-specific demethylase-1 activity. Bioorg Med Chem (2016) 0.75
Stepwise assembly of functional C-terminal REST/NRSF transcriptional repressor complexes as a drug target. Protein Sci (2017) 0.75
The dual role of LSD1 and HDAC3 in STAT5-dependent transcription is determined by protein interactions, binding affinities, motifs and genomic positions. Nucleic Acids Res (2016) 0.75
Activity-dependent Regulation of Histone Lysine Demethylase KDM1A by a Putative Thiol/Disulfide Switch. J Biol Chem (2016) 0.75
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Plant homologs of mammalian MBT-domain protein-regulated KDM1 histone lysine demethylases do not interact with plant Tudor/PWWP/MBT-domain proteins. Biochem Biophys Res Commun (2016) 0.75
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Self-regulated Plk1 recruitment to kinetochores by the Plk1-PBIP1 interaction is critical for proper chromosome segregation. Mol Cell (2006) 3.38
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The Mad2 spindle checkpoint protein undergoes similar major conformational changes upon binding to either Mad1 or Cdc20. Mol Cell (2002) 3.24
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