Next-generation transcriptome assembly.

De novo transcript sequence reconstruction from RNA-seq using the Trinity platform for reference generation and analysis. Nat Protoc (2013) 13.33

Insights into the regulation of protein abundance from proteomic and transcriptomic analyses. Nat Rev Genet (2012) 8.55

Evaluating methods for isolating total RNA and predicting the success of sequencing phylogenetically diverse plant transcriptomes. PLoS One (2012) 1.82

Deep evolutionary comparison of gene expression identifies parallel recruitment of trans-factors in two independent origins of C4 photosynthesis. PLoS Genet (2014) 1.70

The transcriptome of equine peripheral blood mononuclear cells. PLoS One (2015) 1.65

Optimizing de novo assembly of short-read RNA-seq data for phylogenomics. BMC Genomics (2013) 1.52

Deep mRNA sequencing of the Tritonia diomedea brain transcriptome provides access to gene homologues for neuronal excitability, synaptic transmission and peptidergic signalling. PLoS One (2015) 1.45

Successful Recovery of Nuclear Protein-Coding Genes from Small Insects in Museums Using Illumina Sequencing. PLoS One (2015) 1.42

KISSPLICE: de-novo calling alternative splicing events from RNA-seq data. BMC Bioinformatics (2012) 1.42

De Novo Assembly and Characterization of Fruit Transcriptome in Black Pepper (Piper nigrum). PLoS One (2015) 1.40

Quantitative RNA-Seq analysis in non-model species: assessing transcriptome assemblies as a scaffold and the utility of evolutionary divergent genomic reference species. BMC Genomics (2012) 1.38

De novo transcriptome assembly in chili pepper (Capsicum frutescens) to identify genes involved in the biosynthesis of capsaicinoids. PLoS One (2013) 1.34

Biases in small RNA deep sequencing data. Nucleic Acids Res (2013) 1.34

BreakFusion: targeted assembly-based identification of gene fusions in whole transcriptome paired-end sequencing data. Bioinformatics (2012) 1.31

Transcriptomic analysis of Prunus domestica undergoing hypersensitive response to plum pox virus infection. PLoS One (2014) 1.27

TransRate: reference-free quality assessment of de novo transcriptome assemblies. Genome Res (2016) 1.27

RNA-seq and microarray complement each other in transcriptome profiling. BMC Genomics (2012) 1.22

De novo assembly of bacterial transcriptomes from RNA-seq data. Genome Biol (2015) 1.18

Cutoffs and k-mers: implications from a transcriptome study in allopolyploid plants. BMC Genomics (2012) 1.17

Comparative description of ten transcriptomes of newly sequenced invertebrates and efficiency estimation of genomic sampling in non-model taxa. Front Zool (2012) 1.17

Characterization of transcriptomes of cochlear inner and outer hair cells. J Neurosci (2014) 1.14

Transcriptome analysis reveals the time of the fourth round of genome duplication in common carp (Cyprinus carpio). BMC Genomics (2012) 1.14

De novo assembly, gene annotation and marker development using Illumina paired-end transcriptome sequences in celery (Apium graveolens L.). PLoS One (2013) 1.13

A field guide to whole-genome sequencing, assembly and annotation. Evol Appl (2014) 1.12

Corset: enabling differential gene expression analysis for de novo assembled transcriptomes. Genome Biol (2014) 1.12

The transcriptome of Leishmania major in the axenic promastigote stage: transcript annotation and relative expression levels by RNA-seq. BMC Genomics (2013) 1.11

A new model army: Emerging fish models to study the genomics of vertebrate Evo-Devo. J Exp Zool B Mol Dev Evol (2014) 1.11

Next-generation sequence assembly: four stages of data processing and computational challenges. PLoS Comput Biol (2013) 1.07

Transcriptome deep-sequencing and clustering of expressed isoforms from Favia corals. BMC Genomics (2013) 1.07

RNA sequencing: platform selection, experimental design, and data interpretation. Nucleic Acid Ther (2012) 1.07

Bridger: a new framework for de novo transcriptome assembly using RNA-seq data. Genome Biol (2015) 1.03

Analysis of the transcriptome of the Indonesian coelacanth Latimeria menadoensis. BMC Genomics (2013) 1.02

Systems virology: host-directed approaches to viral pathogenesis and drug targeting. Nat Rev Microbiol (2013) 1.02

Genome-wide transcriptome analysis identifies novel gene signatures implicated in human chronic liver disease. Am J Physiol Gastrointest Liver Physiol (2013) 1.01

Characterisation of the wheat (Triticum aestivum L.) transcriptome by de novo assembly for the discovery of phosphate starvation-responsive genes: gene expression in Pi-stressed wheat. BMC Genomics (2013) 1.01

Targeted sequencing for gene discovery and quantification using RNA CaptureSeq. Nat Protoc (2014) 1.01

Transcriptional and microscopic analyses of citrus stem and root responses to Candidatus Liberibacter asiaticus infection. PLoS One (2013) 1.01

Alternative splicing: a potential source of functional innovation in the eukaryotic genome. Int J Evol Biol (2012) 1.00

Genetics of chronic rhinosinusitis: state of the field and directions forward. J Allergy Clin Immunol (2013) 1.00

Comparative transcriptome analysis of epithelial and fiber cells in newborn mouse lenses with RNA sequencing. Mol Vis (2014) 0.99

Widespread Polycistronic Transcripts in Fungi Revealed by Single-Molecule mRNA Sequencing. PLoS One (2015) 0.99

Optimization of de novo transcriptome assembly from high-throughput short read sequencing data improves functional annotation for non-model organisms. BMC Bioinformatics (2012) 0.99

TRAPID: an efficient online tool for the functional and comparative analysis of de novo RNA-Seq transcriptomes. Genome Biol (2013) 0.98

PLEK: a tool for predicting long non-coding RNAs and messenger RNAs based on an improved k-mer scheme. BMC Bioinformatics (2014) 0.98

Functional transcriptomics in the post-ENCODE era. Genome Res (2013) 0.98

Informatics for RNA Sequencing: A Web Resource for Analysis on the Cloud. PLoS Comput Biol (2015) 0.97

Simultaneous digital quantification and fluorescence-based size characterization of massively parallel sequencing libraries. Biotechniques (2013) 0.97

The transcript catalogue of the short-lived fish Nothobranchius furzeri provides insights into age-dependent changes of mRNA levels. BMC Genomics (2013) 0.97

De novo transcriptome assembly of drought tolerant CAM plants, Agave deserti and Agave tequilana. BMC Genomics (2013) 0.97

RNA sequencing read depth requirement for optimal transcriptome coverage in Hevea brasiliensis. BMC Res Notes (2014) 0.95

Deep sequencing reveals differences in the transcriptional landscapes of fibers from two cultivated species of cotton. PLoS One (2012) 0.95

Directional RNA-seq reveals highly complex condition-dependent transcriptomes in E. coli K12 through accurate full-length transcripts assembling. BMC Genomics (2013) 0.94

De novo reconstruction of the Toxoplasma gondii transcriptome improves on the current genome annotation and reveals alternatively spliced transcripts and putative long non-coding RNAs. BMC Genomics (2012) 0.94

Distinguishing the immunostimulatory properties of noncoding RNAs expressed in cancer cells. Proc Natl Acad Sci U S A (2015) 0.94

A quantitative reference transcriptome for Nematostella vectensis early embryonic development: a pipeline for de novo assembly in emerging model systems. Evodevo (2013) 0.94

Genome-wide annotation of microRNA primary transcript structures reveals novel regulatory mechanisms. Genome Res (2015) 0.93

RNA-Seq analysis of isolate- and growth phase-specific differences in the global transcriptomes of enteropathogenic Escherichia coli prototype isolates. Front Microbiol (2015) 0.93

Statistical methods for identifying differentially expressed genes in RNA-Seq experiments. Cell Biosci (2012) 0.93

Comparative analyses of two Geraniaceae transcriptomes using next-generation sequencing. BMC Plant Biol (2013) 0.93

Design of RNA splicing analysis null models for post hoc filtering of Drosophila head RNA-Seq data with the splicing analysis kit (Spanki). BMC Bioinformatics (2013) 0.92

RNA-seq analyses of multiple meristems of soybean: novel and alternative transcripts, evolutionary and functional implications. BMC Plant Biol (2014) 0.92

Toward 959 nematode genomes. Worm (2012) 0.91

CBrowse: a SAM/BAM-based contig browser for transcriptome assembly visualization and analysis. Bioinformatics (2012) 0.91

Altered immunity in crowded locust reduced fungal (Metarhizium anisopliae) pathogenesis. PLoS Pathog (2013) 0.91

De novo assembly of Auricularia polytricha transcriptome using Illumina sequencing for gene discovery and SSR marker identification. PLoS One (2014) 0.90

A SNP resource for Douglas-fir: de novo transcriptome assembly and SNP detection and validation. BMC Genomics (2013) 0.90

Identification of mycoparasitism-related genes against the phytopathogen Sclerotinia sclerotiorum through transcriptome and expression profile analysis in Trichoderma harzianum. BMC Genomics (2014) 0.90

Transcriptome profiling reveals mosaic genomic origins of modern cultivated barley. Proc Natl Acad Sci U S A (2014) 0.90

Decoy activity through microRNAs: the therapeutic implications. Expert Opin Biol Ther (2012) 0.89

Orchidstra: an integrated orchid functional genomics database. Plant Cell Physiol (2013) 0.89

Transcriptome analysis of thermogenic Arum concinnatum reveals the molecular components of floral scent production. Sci Rep (2015) 0.89

Exploring the transcriptome of Atlantic salmon (Salmo salar) skin, a major defense organ. Mar Biotechnol (NY) (2012) 0.89

Genome sequence and analysis of methylotrophic yeast Hansenula polymorpha DL1. BMC Genomics (2013) 0.88

A near complete snapshot of the Zea mays seedling transcriptome revealed from ultra-deep sequencing. Sci Rep (2014) 0.88

The root transcriptome for North American ginseng assembled and profiled across seasonal development. BMC Genomics (2013) 0.88

Epigenetic therapy: use of agents targeting deacetylation and methylation in cancer management. Onco Targets Ther (2013) 0.88

Improving genome-wide scans of positive selection by using protein isoforms of similar length. Genome Biol Evol (2013) 0.88

Strand-specific RNA sequencing in Plasmodium falciparum malaria identifies developmentally regulated long non-coding RNA and circular RNA. BMC Genomics (2015) 0.87

Transcriptome characterisation of the ant Formica exsecta with new insights into the evolution of desaturase genes in social hymenoptera. PLoS One (2013) 0.87

Transcriptomic analysis of lignocellulosic biomass degradation by the anaerobic fungal isolate Orpinomyces sp. strain C1A. Biotechnol Biofuels (2015) 0.87

Toward a common language for biobanking. Eur J Hum Genet (2014) 0.87

CLASS: constrained transcript assembly of RNA-seq reads. BMC Bioinformatics (2013) 0.87

Assembly and annotation of a non-model gastropod (Nerita melanotragus) transcriptome: a comparison of de novo assemblers. BMC Res Notes (2014) 0.86

Transcriptome sequencing as a platform to elucidate molecular components of the diapause response in the Asian tiger mosquito, Aedes albopictus. Physiol Entomol (2013) 0.86

Simultaneous isoform discovery and quantification from RNA-seq. Stat Biosci (2013) 0.86

The human transcriptome: an unfinished story. Genes (Basel) (2012) 0.86

Whole genome sequencing of the black grouse (Tetrao tetrix): reference guided assembly suggests faster-Z and MHC evolution. BMC Genomics (2014) 0.86

Machine learning and genome annotation: a match meant to be? Genome Biol (2013) 0.86

Characterization of the global transcriptome for Pyropia haitanensis (Bangiales, Rhodophyta) and development of cSSR markers. BMC Genomics (2013) 0.86

Heterogeneity of glycolysis in cancers and therapeutic opportunities. Biochem Pharmacol (2014) 0.86

The metamorphosis of amphibian toxicogenomics. Front Genet (2012) 0.86

Advances in genomics for flatfish aquaculture. Genes Nutr (2012) 0.86

The de novo transcriptome and its analysis in the worldwide vegetable pest, Delia antiqua (Diptera: Anthomyiidae). G3 (Bethesda) (2014) 0.86

Shedding some light over the floral metabolism by arum lily (Zantedeschia aethiopica) spathe de novo transcriptome assembly. PLoS One (2014) 0.85

Assessing the utility of the Oxford Nanopore MinION for snake venom gland cDNA sequencing. PeerJ (2015) 0.85

Transcriptomic Changes in Coral Holobionts Provide Insights into Physiological Challenges of Future Climate and Ocean Change. PLoS One (2015) 0.85

Computational approaches for isoform detection and estimation: good and bad news. BMC Bioinformatics (2014) 0.85

Transcriptome assembly, gene annotation and tissue gene expression atlas of the rainbow trout. PLoS One (2015) 0.85

Transcriptional Variation of Diverse Enteropathogenic Escherichia coli Isolates under Virulence-Inducing Conditions. mSystems (2017) 0.84

Optimized deep-targeted proteotranscriptomic profiling reveals unexplored Conus toxin diversity and novel cysteine frameworks. Proc Natl Acad Sci U S A (2015) 0.84

Velvet: algorithms for de novo short read assembly using de Bruijn graphs. Genome Res (2008) 151.16

Mapping and quantifying mammalian transcriptomes by RNA-Seq. Nat Methods (2008) 126.81

BLAT--the BLAST-like alignment tool. Genome Res (2002) 126.78

TopHat: discovering splice junctions with RNA-Seq. Bioinformatics (2009) 81.13

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. Nat Biotechnol (2010) 75.21

RNA-Seq: a revolutionary tool for transcriptomics. Nat Rev Genet (2009) 58.77

The transcriptional landscape of the yeast genome defined by RNA sequencing. Science (2008) 48.99

ABySS: a parallel assembler for short read sequence data. Genome Res (2009) 43.20

Sequencing technologies - the next generation. Nat Rev Genet (2009) 40.57

An Eulerian path approach to DNA fragment assembly. Proc Natl Acad Sci U S A (2001) 31.51

Real-time DNA sequencing from single polymerase molecules. Science (2008) 29.53

ALLPATHS: de novo assembly of whole-genome shotgun microreads. Genome Res (2008) 20.61

Ab initio reconstruction of cell type-specific transcriptomes in mouse reveals the conserved multi-exonic structure of lincRNAs. Nat Biotechnol (2010) 18.44

Fast and SNP-tolerant detection of complex variants and splicing in short reads. Bioinformatics (2010) 17.53

Quake: quality-aware detection and correction of sequencing errors. Genome Biol (2010) 12.52

Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer. Nature (2007) 10.94

Amplification-free Illumina sequencing-library preparation facilitates improved mapping and assembly of (G+C)-biased genomes. Nat Methods (2009) 10.41

Analysis and design of RNA sequencing experiments for identifying isoform regulation. Nat Methods (2010) 10.13

MapSplice: accurate mapping of RNA-seq reads for splice junction discovery. Nucleic Acids Res (2010) 9.80

De novo assembly and analysis of RNA-seq data. Nat Methods (2010) 9.69

Comprehensive comparative analysis of strand-specific RNA sequencing methods. Nat Methods (2010) 9.09

RNA sequencing: advances, challenges and opportunities. Nat Rev Genet (2010) 8.96

Assembly algorithms for next-generation sequencing data. Genomics (2010) 8.56

De novo transcriptome assembly with ABySS. Bioinformatics (2009) 8.38

Annotating genomes with massive-scale RNA sequencing. Genome Biol (2008) 7.73

Detection of splice junctions from paired-end RNA-seq data by SpliceMap. Nucleic Acids Res (2010) 6.95

Ab initio construction of a eukaryotic transcriptome by massively parallel mRNA sequencing. Proc Natl Acad Sci U S A (2009) 6.01

Multi-platform next-generation sequencing of the domestic turkey (Meleagris gallopavo): genome assembly and analysis. PLoS Biol (2010) 5.39

Unlocking short read sequencing for metagenomics. PLoS One (2010) 4.88

deFuse: an algorithm for gene fusion discovery in tumor RNA-Seq data. PLoS Comput Biol (2011) 4.66

Analysis of canonical and non-canonical splice sites in mammalian genomes. Nucleic Acids Res (2000) 4.29

Optimization of de novo transcriptome assembly from next-generation sequencing data. Genome Res (2010) 4.18

Beware of mis-assembled genomes. Bioinformatics (2005) 4.14

Overlapping genes. Annu Rev Genet (1983) 4.08

De novo assembly of chickpea transcriptome using short reads for gene discovery and marker identification. DNA Res (2011) 4.06

RNA-Seq-quantitative measurement of expression through massively parallel RNA-sequencing. Methods (2009) 4.02

TagDust--a program to eliminate artifacts from next generation sequencing data. Bioinformatics (2009) 3.64

FRT-seq: amplification-free, strand-specific transcriptome sequencing. Nat Methods (2010) 3.55

Structure and complexity of a bacterial transcriptome. J Bacteriol (2009) 3.55

Advancing RNA-Seq analysis. Nat Biotechnol (2010) 3.54

Comprehensive polyadenylation site maps in yeast and human reveal pervasive alternative polyadenylation. Cell (2010) 3.42

Revolutions in rapid amplification of cDNA ends: new strategies for polymerase chain reaction cloning of full-length cDNA ends. Anal Biochem (1995) 3.39

RNA-seq: from technology to biology. Cell Mol Life Sci (2009) 3.03

A strand-specific RNA-Seq analysis of the transcriptome of the typhoid bacillus Salmonella typhi. PLoS Genet (2009) 2.87

Whole transcriptome sequencing reveals gene expression and splicing differences in brain regions affected by Alzheimer's disease. PLoS One (2011) 2.80

Rnnotator: an automated de novo transcriptome assembly pipeline from stranded RNA-Seq reads. BMC Genomics (2010) 2.62

SeqTrim: a high-throughput pipeline for pre-processing any type of sequence read. BMC Bioinformatics (2010) 2.43

Reverse transcriptase template switching and false alternative transcripts. Genomics (2006) 2.38

An overview of the Hadoop/MapReduce/HBase framework and its current applications in bioinformatics. BMC Bioinformatics (2010) 2.37

De novo assembly of short sequence reads. Brief Bioinform (2010) 2.29

Validation of two ribosomal RNA removal methods for microbial metatranscriptomics. Nat Methods (2010) 2.21

De novo analysis of transcriptome dynamics in the migratory locust during the development of phase traits. PLoS One (2010) 2.19

Amplification-free digital gene expression profiling from minute cell quantities. Nat Methods (2010) 2.07

Properties of overlapping genes are conserved across microbial genomes. Genome Res (2004) 2.01

A metagenomic analysis of pandemic influenza A (2009 H1N1) infection in patients from North America. PLoS One (2010) 1.99

Massive parallel sequencing of mRNA in identification of unannotated salinity stress-inducible transcripts in rice (Oryza sativa L.). BMC Genomics (2010) 1.96

Assembling genomes using short-read sequencing technology. Genome Biol (2010) 1.95

De novo transcriptome sequencing in Anopheles funestus using Illumina RNA-seq technology. PLoS One (2010) 1.95

Construction of normalized RNA-seq libraries for next-generation sequencing using the crab duplex-specific nuclease. Curr Protoc Mol Biol (2011) 1.88

De novo assembly and validation of planaria transcriptome by massive parallel sequencing and shotgun proteomics. Genome Res (2011) 1.70

A parallel algorithm for error correction in high-throughput short-read data on CUDA-enabled graphics hardware. J Comput Biol (2010) 1.68

Genome assembly quality: assessment and improvement using the neutral indel model. Genome Res (2010) 1.64

Sensitive gene fusion detection using ambiguously mapping RNA-Seq read pairs. Bioinformatics (2011) 1.58

Comparative study of overlapping genes in the genomes of Mycoplasma genitalium and Mycoplasma pneumoniae. Nucleic Acids Res (1999) 1.51

A comparison of single molecule and amplification based sequencing of cancer transcriptomes. PLoS One (2011) 1.44

Overlapping genes in vertebrate genomes. Comput Biol Chem (2005) 1.43

A garter snake transcriptome: pyrosequencing, de novo assembly, and sex-specific differences. BMC Genomics (2010) 1.29

Composite transcriptome assembly of RNA-seq data in a sheep model for delayed bone healing. BMC Genomics (2011) 1.13

Ribosomal RNA depletion for massively parallel bacterial RNA-sequencing applications. Methods Mol Biol (2011) 1.12

The transcriptional landscape of the yeast genome defined by RNA sequencing. Science (2008) 48.99

Hybrid error correction and de novo assembly of single-molecule sequencing reads. Nat Biotechnol (2012) 10.31

Metagenomic discovery of biomass-degrading genes and genomes from cow rumen. Science (2011) 6.93

Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression. Mol Cell Biol (2004) 6.55

A novel class of small RNAs in mouse spermatogenic cells. Genes Dev (2006) 5.85

A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury. Nat Med (2005) 3.26

ES cell pluripotency and germ-layer formation require the SWI/SNF chromatin remodeling component BAF250a. Proc Natl Acad Sci U S A (2008) 3.15

Close association of RNA polymerase II and many transcription factors with Pol III genes. Proc Natl Acad Sci U S A (2010) 2.90

Lives of a heart cell: tracing the origins of cardiac progenitors. Cell Stem Cell (2008) 2.68

A novel monoclonal antibody against DOG1 is a sensitive and specific marker for gastrointestinal stromal tumors. Am J Surg Pathol (2008) 2.68

Rnnotator: an automated de novo transcriptome assembly pipeline from stranded RNA-Seq reads. BMC Genomics (2010) 2.62

Comprehensive annotation of the transcriptome of the human fungal pathogen Candida albicans using RNA-seq. Genome Res (2010) 2.34

Validation of two ribosomal RNA removal methods for microbial metatranscriptomics. Nat Methods (2010) 2.21

HOXB13 is a susceptibility gene for prostate cancer: results from the International Consortium for Prostate Cancer Genetics (ICPCG). Hum Genet (2012) 2.18

Toeprint analysis of the positioning of translation apparatus components at initiation and termination codons of fungal mRNAs. Methods (2002) 2.04

BAF250B-associated SWI/SNF chromatin-remodeling complex is required to maintain undifferentiated mouse embryonic stem cells. Stem Cells (2008) 2.02

Cyclophilin A/Cluster of Differentiation 147 Interactions Participate in Early Brain Injury After Subarachnoid Hemorrhage in Rats. Crit Care Med (2015) 2.01

ALE: a generic assembly likelihood evaluation framework for assessing the accuracy of genome and metagenome assemblies. Bioinformatics (2013) 1.89

Regulatory relationship among piwi, pumilio, and bag-of-marbles in Drosophila germline stem cell self-renewal and differentiation. Curr Biol (2005) 1.88

Second-generation tetracycline-regulatable promoter: repositioned tet operator elements optimize transactivator synergy while shorter minimal promoter offers tight basal leakiness. J Gene Med (2004) 1.80

Genome-wide association study in Chinese men identifies two new prostate cancer risk loci at 9q31.2 and 19q13.4. Nat Genet (2012) 1.78

Comparison of the trivalent live attenuated vs. inactivated influenza vaccines among U.S. military service members. Vaccine (2009) 1.70

Genetic variants in STAT4 and HLA-DQ genes confer risk of hepatitis B virus-related hepatocellular carcinoma. Nat Genet (2012) 1.64

Human rhinoviruses in Chinese adults with acute respiratory tract infection. J Infect (2010) 1.58

Targeted conditional gene knockout in human embryonic stem cells. Cell Res (2010) 1.53

Coxsackievirus A21, enterovirus 68, and acute respiratory tract infection, China. Emerg Infect Dis (2012) 1.52

Incidence of mumps and immunity to measles, mumps and rubella among US military recruits, 2000-2004. Vaccine (2007) 1.47

Stem cell therapy for erectile dysfunction: a critical review. Stem Cells Dev (2011) 1.44

Sustained whole-body functional rescue in congestive heart failure and muscular dystrophy hamsters by systemic gene transfer. Circulation (2005) 1.42

Oct3/4 and Sox2 are significantly associated with an unfavorable clinical outcome in human esophageal squamous cell carcinoma. Anticancer Res (2009) 1.41

p21-activated kinase 1 predicts recurrence and survival in patients with non-metastatic clear cell renal cell carcinoma. Int J Urol (2015) 1.40

A prospective, randomized clinical trial comparing plasmakinetic resection of the prostate with holmium laser enucleation of the prostate based on a 2-year followup. J Urol (2012) 1.37

Metabolically favorable remodeling of human adipose tissue by human adenovirus type 36. Diabetes (2008) 1.35

Inactivation of PKCtheta leads to increased susceptibility to obesity and dietary insulin resistance in mice. Am J Physiol Endocrinol Metab (2006) 1.34

Systematic confirmation study of reported prostate cancer risk-associated single nucleotide polymorphisms in Chinese men. Cancer Sci (2011) 1.32

Etiology and clinical characterization of respiratory virus infections in adult patients attending an emergency department in Beijing. PLoS One (2012) 1.31

IL-17 response mediates acute lung injury induced by the 2009 pandemic influenza A (H1N1) virus. Cell Res (2011) 1.30

Coronary development is regulated by ATP-dependent SWI/SNF chromatin remodeling component BAF180. Dev Biol (2008) 1.26

Increased hypothalamic protein tyrosine phosphatase 1B contributes to leptin resistance with age. Endocrinology (2006) 1.26

Genetic markers associated with early cancer-specific mortality following prostatectomy. Cancer (2013) 1.25

Detection of HPV DNA in esophageal cancer specimens from different regions and ethnic groups: a descriptive study. BMC Cancer (2010) 1.22

Evolution of extreme resistance to ionizing radiation via genetic adaptation of DNA repair. Elife (2014) 1.22

Epigenetic roles of MLL oncoproteins are dependent on NF-κB. Cancer Cell (2013) 1.20

Adipose tissue-derived stem cells secrete CXCL5 cytokine with neurotrophic effects on cavernous nerve regeneration. J Sex Med (2010) 1.16

HF diets increase hypothalamic PTP1B and induce leptin resistance through both leptin-dependent and -independent mechanisms. Am J Physiol Endocrinol Metab (2008) 1.16

Replication and cumulative effects of GWAS-identified genetic variations for prostate cancer in Asians: a case-control study in the ChinaPCa consortium. Carcinogenesis (2011) 1.15

Polyphenolic compounds from Artemisia dracunculus L. inhibit PEPCK gene expression and gluconeogenesis in an H4IIE hepatoma cell line. Am J Physiol Endocrinol Metab (2007) 1.15

A dynamic model for genome-wide association studies. Hum Genet (2011) 1.15

A novel germline mutation in HOXB13 is associated with prostate cancer risk in Chinese men. Prostate (2012) 1.15

Systematic identification of the genes affecting glycogen storage in the yeast Saccharomyces cerevisiae: implication of the vacuole as a determinant of glycogen level. Mol Cell Proteomics (2002) 1.14

The prevalence and regulation of antisense transcripts in Schizosaccharomyces pombe. PLoS One (2010) 1.13

WU and KI polyomavirus present in the respiratory tract of children, but not in immunocompetent adults. J Clin Virol (2008) 1.12

Role of the Nrf2-ARE pathway in early brain injury after experimental subarachnoid hemorrhage. J Neurosci Res (2011) 1.11

Bipolar transurethral resection in saline vs traditional monopolar resection of the prostate: results of a randomized trial with a 2-year follow-up. BJU Int (2010) 1.11

BioPig: a Hadoop-based analytic toolkit for large-scale sequence data. Bioinformatics (2013) 1.11

Predictive performance of prostate cancer risk in Chinese men using 33 reported prostate cancer risk-associated SNPs. Prostate (2011) 1.10

Highly efficient derivation of ventricular cardiomyocytes from induced pluripotent stem cells with a distinct epigenetic signature. Cell Res (2011) 1.08

Culture effects of epidermal growth factor (EGF) and basic fibroblast growth factor (bFGF) on cryopreserved human adipose-derived stromal/stem cell proliferation and adipogenesis. J Tissue Eng Regen Med (2009) 1.07

Characterization of human coronavirus etiology in Chinese adults with acute upper respiratory tract infection by real-time RT-PCR assays. PLoS One (2012) 1.04

Synthesis and anticancer properties of water-soluble zinc ionophores. Cancer Res (2008) 1.01

SWI/SNF protein component BAF250a regulates cardiac progenitor cell differentiation by modulating chromatin accessibility during second heart field development. J Biol Chem (2012) 1.01

Evaluation of reported prostate cancer risk-associated SNPs from genome-wide association studies of various racial populations in Chinese men. Prostate (2013) 1.00

Prevalence of human coronaviruses in adults with acute respiratory tract infections in Beijing, China. J Med Virol (2011) 1.00

Molecular characterization of Trichinella spiralis aminopeptidase and its potential as a novel vaccine candidate antigen against trichinellosis in BALB/c mice. Parasit Vectors (2013) 0.99

Influenza A/H1N1 2009 pandemic and respiratory virus infections, Beijing, 2009-2010. PLoS One (2012) 0.99

Differential gene expression in tamoxifen-resistant breast cancer cells revealed by a new analytical model of RNA-Seq data. PLoS One (2012) 0.99

Prediction of prostate cancer from prostate biopsy in Chinese men using a genetic score derived from 24 prostate cancer risk-associated SNPs. Prostate (2013) 0.98

A comparative study on the individual and combined effects of baicalin and jasminoidin on focal cerebral ischemia-reperfusion injury. Brain Res (2006) 0.98

De novo transcriptome assembly of drought tolerant CAM plants, Agave deserti and Agave tequilana. BMC Genomics (2013) 0.97

How to cluster gene expression dynamics in response to environmental signals. Brief Bioinform (2011) 0.96

Exogenous and endogenous hormones in relation to glioma in women: a meta-analysis of 11 case-control studies. PLoS One (2013) 0.96

Evaluation of the protective potential of brain microvascular endothelial cell autophagy on blood-brain barrier integrity during experimental cerebral ischemia-reperfusion injury. Transl Stroke Res (2014) 0.95

20-Hydroxyecdysone decreases weight and hyperglycemia in a diet-induced obesity mice model. Am J Physiol Endocrinol Metab (2009) 0.95

Clinical toxicology in China: current situation and future development. Clin Toxicol (Phila) (2009) 0.95

Functional clustering of periodic transcriptional profiles through ARMA(p,q). PLoS One (2010) 0.94

New polyethyleneglycol-functionalized texaphyrins: synthesis and in vitro biological studies. Dalton Trans (2006) 0.93

Statistical methods for identifying differentially expressed genes in RNA-Seq experiments. Cell Biosci (2012) 0.93

Genome-wide association study identifies a new locus JMJD1C at 10q21 that may influence serum androgen levels in men. Hum Mol Genet (2012) 0.93

AAV8-mediated gene transfer of interleukin-4 to endogenous beta-cells prevents the onset of diabetes in NOD mice. Mol Ther (2008) 0.93

Long non-coding RNAs as potential biomarkers and therapeutic targets for gliomas. Med Hypotheses (2013) 0.93

[Study on the situation of plague in Junggar Basin of China]. Zhonghua Liu Xing Bing Xue Za Zhi (2008) 0.93

Penoscrotal extramammary Paget's disease: surgical techniques and follow-up experiences with thirty patients. Asian J Androl (2013) 0.92

Tumor localization and antitumor efficacy of novel sapphyrin compounds. Mol Cancer Ther (2006) 0.92

Systems mapping: how to improve the genetic mapping of complex traits through design principles of biological systems. BMC Syst Biol (2011) 0.92

Genome-wide association studies for bivariate sparse longitudinal data. Hum Hered (2011) 0.92

The impact of prenatal androgens on vaginal and urogenital sinus development in the female mouse. J Urol (2003) 0.92

Predictors for long-term seizure outcome in juvenile myoclonic epilepsy: 25-63 years of follow-up. Epilepsia (2012) 0.92

Comparative genomics reveals multistep pathogenesis of E2A-PBX1 acute lymphoblastic leukemia. J Clin Invest (2015) 0.92

Activating transcription factor 3 is up-regulated in patients with hypospadias. Pediatr Res (2005) 0.91

Dynamic semiparametric Bayesian models for genetic mapping of complex trait with irregular longitudinal data. Stat Med (2012) 0.91

Recombinant human erythropoietin (rhEPO) alleviates early brain injury following subarachnoid hemorrhage in rats: possible involvement of Nrf2-ARE pathway. Cytokine (2010) 0.89

Metastatic tumors of the penis: a report of 8 cases and review of the literature. Medicine (Baltimore) (2015) 0.89

Neuroprotective effects of water-soluble Ganoderma lucidum polysaccharides on cerebral ischemic injury in rats. J Ethnopharmacol (2010) 0.89

Inhibition of autophagy contributes to melatonin-mediated neuroprotection against transient focal cerebral ischemia in rats. J Pharmacol Sci (2014) 0.89

A model for transgenerational imprinting variation in complex traits. PLoS One (2010) 0.89

The effect of transparent TESTA2 on seed fatty acid biosynthesis and tolerance to environmental stresses during young seedling establishment in Arabidopsis. Plant Physiol (2012) 0.89

NVP-BEZ235, a novel dual PI3K/mTOR inhibitor, enhances the radiosensitivity of human glioma stem cells in vitro. Acta Pharmacol Sin (2013) 0.89

A genome-wide association study reveals that variants within the HLA region are associated with risk for nonobstructive azoospermia. Am J Hum Genet (2012) 0.88