Published in Immunity on September 15, 2011
Extrathymically generated regulatory T cells control mucosal TH2 inflammation. Nature (2012) 4.33
Microbiota-Dependent Sequelae of Acute Infection Compromise Tissue-Specific Immunity. Cell (2015) 4.28
The alarmin IL-33 promotes regulatory T-cell function in the intestine. Nature (2014) 3.10
Self-antigen-driven activation induces instability of regulatory T cells during an inflammatory autoimmune response. Immunity (2013) 2.41
Molecular mechanisms that control the expression and activity of Bcl-6 in TH1 cells to regulate flexibility with a TFH-like gene profile. Nat Immunol (2012) 2.26
Transcription factor Foxp3 and its protein partners form a complex regulatory network. Nat Immunol (2012) 2.10
Functionally distinct subsets of human FOXP3+ Treg cells that phenotypically mirror effector Th cells. Blood (2012) 2.00
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Role and species-specific expression of colon T cell homing receptor GPR15 in colitis. Nat Immunol (2014) 1.58
Control of inflammation by integration of environmental cues by regulatory T cells. J Clin Invest (2013) 1.43
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Early infection with respiratory syncytial virus impairs regulatory T cell function and increases susceptibility to allergic asthma. Nat Med (2012) 1.33
GATA-3 expression identifies a high-risk subset of PTCL, NOS with distinct molecular and clinical features. Blood (2014) 1.32
Once a Treg, always a Treg? Immunol Rev (2014) 1.27
Experimental Models of Inflammatory Bowel Diseases. Cell Mol Gastroenterol Hepatol (2015) 1.20
Function of a Foxp3 cis-element in protecting regulatory T cell identity. Cell (2014) 1.19
Regulatory T cell reprogramming toward a Th2-cell-like lineage impairs oral tolerance and promotes food allergy. Immunity (2015) 1.19
Mechanisms underlying helper T-cell plasticity: implications for immune-mediated disease. J Allergy Clin Immunol (2013) 1.19
Hypoxia and hypoxia-inducible factors as regulators of T cell development, differentiation, and function. Immunol Res (2013) 1.19
MyD88 Adaptor-Dependent Microbial Sensing by Regulatory T Cells Promotes Mucosal Tolerance and Enforces Commensalism. Immunity (2015) 1.17
CD4(+) T-cell subsets in intestinal inflammation. Immunol Rev (2013) 1.17
Dynamic expression of transcription factors T-bet and GATA-3 by regulatory T cells maintains immunotolerance. Nat Immunol (2014) 1.16
Bcl6 controls the Th2 inflammatory activity of regulatory T cells by repressing Gata3 function. J Immunol (2012) 1.13
DNA binding by GATA transcription factor suggests mechanisms of DNA looping and long-range gene regulation. Cell Rep (2012) 1.12
The symphony of the ninth: the development and function of Th9 cells. Curr Opin Immunol (2012) 1.12
GATA-3 controls the maintenance and proliferation of T cells downstream of TCR and cytokine signaling. Nat Immunol (2013) 1.06
Polar opposites: Erk direction of CD4 T cell subsets. J Immunol (2012) 1.06
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Defining characteristics of classical Hodgkin lymphoma microenvironment T-helper cells. Blood (2013) 1.02
Multiple treg suppressive modules and their adaptability. Front Immunol (2012) 1.01
IL-6 controls susceptibility to helminth infection by impeding Th2 responsiveness and altering the Treg phenotype in vivo. Eur J Immunol (2013) 1.01
Treg functional stability and its responsiveness to the microenvironment. Immunol Rev (2014) 1.01
Itch expression by Treg cells controls Th2 inflammatory responses. J Clin Invest (2013) 1.00
Foxp3(+) T cells expressing RORγt represent a stable regulatory T-cell effector lineage with enhanced suppressive capacity during intestinal inflammation. Mucosal Immunol (2015) 1.00
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Heligmosomoides polygyrus bakeri infection activates colonic Foxp3+ T cells enhancing their capacity to prevent colitis. J Immunol (2013) 0.97
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Helminth infections decrease host susceptibility to immune-mediated diseases. J Immunol (2014) 0.93
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T helper 2 (Th2) cell differentiation, type 2 innate lymphoid cell (ILC2) development and regulation of interleukin-4 (IL-4) and IL-13 production. Cytokine (2015) 0.92
T-cell selection and intestinal homeostasis. Immunol Rev (2014) 0.92
Regulatory T cell identity: formation and maintenance. Trends Immunol (2015) 0.91
Embryonic trophoblasts induce decidual regulatory T cell differentiation and maternal-fetal tolerance through thymic stromal lymphopoietin instructing dendritic cells. J Immunol (2014) 0.90
Cellular and molecular determinants for the development of natural and induced regulatory T cells. Hum Immunol (2012) 0.88
Regulatory T cells and immune tolerance in the intestine. Cold Spring Harb Perspect Biol (2013) 0.88
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The interplay between regulatory T cells and metabolism in immune regulation. Oncoimmunology (2013) 0.86
Highlights of the advances in basic immunology in 2011. Cell Mol Immunol (2012) 0.86
The environment of regulatory T cell biology: cytokines, metabolites, and the microbiome. Front Immunol (2015) 0.86
Regulatory cells and transplantation tolerance. Cold Spring Harb Perspect Med (2013) 0.86
Origin and functions of pro-inflammatory cytokine producing Foxp3+ regulatory T cells. Cytokine (2015) 0.85
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Anti-inflammatory immune skewing is atheroprotective: Apoe−/−FcγRIIb−/− mice develop fibrous carotid plaques. J Am Heart Assoc (2014) 0.85
MeCP2 enforces Foxp3 expression to promote regulatory T cells' resilience to inflammation. Proc Natl Acad Sci U S A (2014) 0.85
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FOXP3(+) Treg Cells and Gender Bias in Autoimmune Diseases. Front Immunol (2015) 0.83
Plasticity within the αβ⁺CD4⁺ T-cell lineage: when, how and what for? Open Biol (2013) 0.83
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Ubiquitin specific protease 21 is dispensable for normal development, hematopoiesis and lymphocyte differentiation. PLoS One (2015) 0.82
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Regulatory T cells use "Itch" to control asthma. J Clin Invest (2013) 0.82
Two histone/protein acetyltransferases, CBP and p300, are indispensable for Foxp3+ T-regulatory cell development and function. Mol Cell Biol (2014) 0.82
Inflammation-associated genes: risks and benefits to Foxp3+ regulatory T-cell function. Immunology (2015) 0.82
Regulatory T cells in allergic diseases. J Allergy Clin Immunol (2016) 0.80
Inflammation negatively regulates FOXP3 and regulatory T-cell function via DBC1. Proc Natl Acad Sci U S A (2015) 0.80
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IL-33 Receptor-Expressing Regulatory T Cells Are Highly Activated, Th2 Biased and Suppress CD4 T Cell Proliferation through IL-10 and TGFβ Release. PLoS One (2016) 0.79
Regulatory T cells GATA have it. Immunity (2011) 0.79
Ubiquitin-dependent regulation of Foxp3 and Treg function. Immunol Rev (2015) 0.78
T-bet Regulates Natural Regulatory T Cell Afferent Lymphatic Migration and Suppressive Function. J Immunol (2016) 0.78
Alternatively Activated Macrophages Boost Induced Regulatory T and Th17 Cell Responses during Immunotherapy for Colitis. J Immunol (2016) 0.78
Empowering Regulatory T Cells in Autoimmunity. Trends Mol Med (2016) 0.78
MiR-125a-5p Decreases the Sensitivity of Treg cells Toward IL-6-Mediated Conversion by Inhibiting IL-6R and STAT3 Expression. Sci Rep (2015) 0.78
Along the Axis between Type 1 and Type 2 Immunity; Principles Conserved in Evolution from Fish to Mammals. Biology (Basel) (2015) 0.77
BRG1-mediated immune tolerance: facilitation of Treg activation and partial independence of chromatin remodelling. EMBO J (2013) 0.77
Regulatory T cells and the control of the allergic response. J Allergy (Cairo) (2012) 0.77
Histone methylation mediates plasticity of human FOXP3(+) regulatory T cells by modulating signature gene expressions. Immunology (2014) 0.77
Excessive expression of miR-27 impairs Treg-mediated immunological tolerance. J Clin Invest (2017) 0.77
Regulatory T cell Itch reins in Th2 inflammation. Cell Mol Immunol (2014) 0.76
Spontaneous Intestinal Tumorigenesis in Apc (/Min+) Mice Requires Altered T Cell Development with IL-17A. J Immunol Res (2015) 0.76
Itm2a, a target gene of GATA-3, plays a minimal role in regulating the development and function of T cells. PLoS One (2014) 0.76
Ubiquitous points of control over regulatory T cells. J Mol Med (Berl) (2014) 0.76
DNA Demethylation of the Foxp3 Enhancer Is Maintained through Modulation of Ten-Eleven-Translocation and DNA Methyltransferases. Mol Cells (2016) 0.76
IL-33 Effect on Quantitative Changes of CD4(+)CD25(high)FOXP3(+) Regulatory T Cells in Children with Type 1 Diabetes. Mediators Inflamm (2016) 0.76
Tumor-associated changes in intestinal epithelial cells cause local accumulation of KLRG1(+) GATA3(+) regulatory T cells in mice. Immunology (2017) 0.76
Nematodes and human therapeutic trials for inflammatory disease. Parasite Immunol (2016) 0.75
ERBIN deficiency links STAT3 and TGF-β pathway defects with atopy in humans. J Exp Med (2017) 0.75
Tissue adaptation: Implications for gut immunity and tolerance. J Exp Med (2017) 0.75
Transcriptional regulation of T cell metabolism. Mol Immunol (2015) 0.75
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Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol (2003) 38.57
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A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat Immunol (2005) 27.17
An essential role for Scurfin in CD4+CD25+ T regulatory cells. Nat Immunol (2003) 19.16
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Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse. Nat Genet (2001) 14.15
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X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy. Nat Genet (2001) 10.92
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A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival. Immunity (2001) 9.45
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Transforming growth factor-beta 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset. Nat Immunol (2008) 6.76
Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control T(H)2 responses. Nature (2009) 6.65
Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression. Nature (2007) 6.58
IL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cells. Nat Immunol (2008) 6.41
Cutting edge: regulatory T cells induce CD4+CD25-Foxp3- T cells or are self-induced to become Th17 cells in the absence of exogenous TGF-beta. J Immunol (2007) 6.32
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