Molecular mechanisms regulating Th1 immune responses.

A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat Immunol (2005) 27.17

Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells. Immunity (2009) 9.73

New insights into the regulation of T cells by gamma(c) family cytokines. Nat Rev Immunol (2009) 5.57

IL-21 is produced by Th17 cells and drives IL-17 production in a STAT3-dependent manner. J Biol Chem (2007) 4.77

Follicular helper T cells: lineage and location. Immunity (2009) 4.75

Induction and molecular signature of pathogenic TH17 cells. Nat Immunol (2012) 4.43

Phenotypical and functional specialization of FOXP3+ regulatory T cells. Nat Rev Immunol (2011) 4.29

Comprehensive epigenetic profiling identifies multiple distal regulatory elements directing transcription of the gene encoding interferon-gamma. Nat Immunol (2007) 3.72

Cross-regulation of signaling pathways by interferon-gamma: implications for immune responses and autoimmune diseases. Immunity (2009) 3.51

The function of follicular helper T cells is regulated by the strength of T cell antigen receptor binding. Nat Immunol (2009) 3.44

Retinoic acid inhibits Th17 polarization and enhances FoxP3 expression through a Stat-3/Stat-5 independent signaling pathway. Blood (2007) 3.33

Activation, coactivation, and costimulation of resting human natural killer cells. Immunol Rev (2006) 3.30

Early Th1 cell differentiation is marked by a Tfh cell-like transition. Immunity (2011) 3.24

An essential role of the transcription factor GATA-3 for the function of regulatory T cells. Immunity (2011) 3.11

Heterogeneity and plasticity of T helper cells. Cell Res (2009) 3.09

T-bet is required for optimal proinflammatory CD4+ T-cell trafficking. Blood (2005) 2.95

Cytokines and transcription factors that regulate T helper cell differentiation: new players and new insights. J Clin Immunol (2003) 2.93

Notch directly regulates Gata3 expression during T helper 2 cell differentiation. Immunity (2007) 2.88

IL-1 family members and STAT activators induce cytokine production by Th2, Th17, and Th1 cells. Proc Natl Acad Sci U S A (2009) 2.83

MicroRNA-29 regulates T-box transcription factors and interferon-γ production in helper T cells. Immunity (2011) 2.71

Interleukin-2 at the crossroads of effector responses, tolerance, and immunotherapy. Immunity (2013) 2.69

Skin-resident murine dendritic cell subsets promote distinct and opposing antigen-specific T helper cell responses. Immunity (2011) 2.58

Modulation of cytokine receptors by IL-2 broadly regulates differentiation into helper T cell lineages. Nat Immunol (2011) 2.47

TSLP regulates intestinal immunity and inflammation in mouse models of helminth infection and colitis. J Exp Med (2009) 2.45

IL-2 family cytokines: new insights into the complex roles of IL-2 as a broad regulator of T helper cell differentiation. Curr Opin Immunol (2011) 2.44

Dysregulated T cell expression of TIM3 in multiple sclerosis. J Exp Med (2006) 2.43

Priming for T helper type 2 differentiation by interleukin 2-mediated induction of interleukin 4 receptor alpha-chain expression. Nat Immunol (2008) 2.31

Imaging of effector memory T cells during a delayed-type hypersensitivity reaction and suppression by Kv1.3 channel block. Immunity (2008) 2.23

Regulation of neutrophils by interferon-γ limits lung inflammation during tuberculosis infection. J Exp Med (2011) 2.22

Memory T cell RNA rearrangement programmed by heterogeneous nuclear ribonucleoprotein hnRNPLL. Immunity (2008) 2.13

Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy. Cell (2016) 2.00

The IL-23-IL-17 axis in inflammatory arthritis. Nat Rev Rheumatol (2015) 1.89

The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes. Proc Natl Acad Sci U S A (2009) 1.86

SHP-1 and SHP-2 in T cells: two phosphatases functioning at many levels. Immunol Rev (2009) 1.78

Umbilical cord plasma 25-hydroxyvitamin D concentration and immune function at birth: the Urban Environment and Childhood Asthma study. Clin Exp Allergy (2011) 1.76

Interleukin-6/STAT3 signaling regulates the ability of naive T cells to acquire B-cell help capacities. Blood (2008) 1.68

Ets-1, a functional cofactor of T-bet, is essential for Th1 inflammatory responses. J Exp Med (2005) 1.66

Pathogen-induced inflammatory environment controls effector and memory CD8+ T cell differentiation. J Immunol (2011) 1.66

IL-2 production in developing Th1 cells is regulated by heterodimerization of RelA and T-bet and requires T-bet serine residue 508. J Exp Med (2005) 1.64

Single-dose mucosal immunization with a candidate universal influenza vaccine provides rapid protection from virulent H5N1, H3N2 and H1N1 viruses. PLoS One (2010) 1.64

Helper T cell diversity and plasticity. Curr Opin Immunol (2012) 1.63

Tim-2 regulates T helper type 2 responses and autoimmunity. J Exp Med (2005) 1.63

Notch and presenilin regulate cellular expansion and cytokine secretion but cannot instruct Th1/Th2 fate acquisition. PLoS One (2008) 1.56

STAT3 in CD4+ T helper cell differentiation and inflammatory diseases. Cytokine (2009) 1.55

Levels of dipeptidyl peptidase IV/CD26 substrates neuropeptide Y and vasoactive intestinal peptide in rheumatoid arthritis patients. Rheumatol Int (2013) 1.53

Cutting edge: influence of Tmevpg1, a long intergenic noncoding RNA, on the expression of Ifng by Th1 cells. J Immunol (2012) 1.48

Cytolytic CD4(+) T cells in viral immunity. Expert Rev Vaccines (2010) 1.47

T cell activation induces proteasomal degradation of Argonaute and rapid remodeling of the microRNA repertoire. J Exp Med (2013) 1.42

Dectin-1 diversifies Aspergillus fumigatus-specific T cell responses by inhibiting T helper type 1 CD4 T cell differentiation. J Exp Med (2011) 1.38

Fiber-optic microsphere-based antibody array for the analysis of inflammatory cytokines in saliva. Anal Chem (2009) 1.35

In silico identified CCR4 antagonists target regulatory T cells and exert adjuvant activity in vaccination. Proc Natl Acad Sci U S A (2008) 1.34

Therapeutic modulators of STAT signalling for human diseases. Nat Rev Drug Discov (2013) 1.33

Simvastatin promotes Th2-type responses through the induction of the chitinase family member Ym1 in dendritic cells. Proc Natl Acad Sci U S A (2006) 1.33

Gfi-1 plays an important role in IL-2-mediated Th2 cell expansion. Proc Natl Acad Sci U S A (2006) 1.32

Interferon gamma in successful pregnancies. Biol Reprod (2009) 1.32

Tristetraprolin mediates interferon-gamma mRNA decay. J Biol Chem (2009) 1.30

Cytosolic phospholipase A2 alpha-deficient mice are resistant to experimental autoimmune encephalomyelitis. J Exp Med (2005) 1.30

Dysregulation of signaling pathways in CD45-deficient NK cells leads to differentially regulated cytotoxicity and cytokine production. Proc Natl Acad Sci U S A (2006) 1.30

The adjuvant activity of CpG DNA requires T-bet expression in dendritic cells. Proc Natl Acad Sci U S A (2005) 1.30

IL-2 and autocrine IL-4 drive the in vivo development of antigen-specific Th2 T cells elicited by nematode parasites. J Immunol (2005) 1.29

Identification of an IFN-γ/mast cell axis in a mouse model of chronic asthma. J Clin Invest (2011) 1.27

Interferon-gamma induces chronic active myocarditis and cardiomyopathy in transgenic mice. Am J Pathol (2007) 1.26

IL-2 and antigen dose differentially regulate perforin- and FasL-mediated cytolytic activity in antigen specific CD4+ T cells. Cell Immunol (2009) 1.26

A fundamental bimodal role for neuropeptide Y1 receptor in the immune system. J Exp Med (2005) 1.25

An intrinsic mechanism predisposes Foxp3-expressing regulatory T cells to Th2 conversion in vivo. J Immunol (2010) 1.24

STAT1 is essential for antimicrobial effector function but dispensable for gamma interferon production during Toxoplasma gondii infection. Infect Immun (2004) 1.23

T-bet, a Th1 transcription factor regulates the expression of Tim-3. Eur J Immunol (2010) 1.21

Convergence of Itch-induced ubiquitination with MEKK1-JNK signaling in Th2 tolerance and airway inflammation. J Clin Invest (2006) 1.21

Antioxidants, inflammation and cardiovascular disease. World J Cardiol (2014) 1.20

T-bet deficiency attenuates renal injury in experimental crescentic glomerulonephritis. J Am Soc Nephrol (2008) 1.20

Mechanisms underlying helper T-cell plasticity: implications for immune-mediated disease. J Allergy Clin Immunol (2013) 1.19

IFN-gamma regulates the requirement for IL-17 in proteoglycan-induced arthritis. J Immunol (2009) 1.18

Multi-tasking of helper T cells. Immunology (2010) 1.17

Immunogenicity of Anaplasma marginale type IV secretion system proteins in a protective outer membrane vaccine. Infect Immun (2007) 1.17

Epigenetics and T helper 1 differentiation. Immunology (2008) 1.17

Thymic selection pathway regulates the effector function of CD4 T cells. J Exp Med (2007) 1.15

Deviation from a strong Th1-dominated to a modest Th17-dominated CD4 T cell response in the absence of IL-12p40 and type I IFNs sustains protective CD8 T cells. J Immunol (2008) 1.14

Predominance of type 1 CD4+ T cells in human abdominal aortic aneurysm. Clin Exp Immunol (2005) 1.13

Characterization of T-bet and eomes in peripheral human immune cells. Front Immunol (2014) 1.13

Interferon-γ and systemic autoimmunity. Discov Med (2013) 1.13

IRF4 and its regulators: evolving insights into the pathogenesis of inflammatory arthritis? Immunol Rev (2010) 1.12

Th 17 cells interplay with Foxp3+ Tregs in regulation of inflammation and autoimmunity. Front Biosci (Landmark Ed) (2010) 1.11

The transcription factor NFATc2 controls IL-6-dependent T cell activation in experimental colitis. J Exp Med (2008) 1.10

Glomerulonephritis, Th1 and Th2: what's new? Clin Exp Immunol (2005) 1.10

Atherosclerosis and systemic lupus erythematosus: mechanistic basis of the association. Curr Opin Immunol (2007) 1.09

Probiotic Leuconostoc mesenteroides ssp. cremoris and Streptococcus thermophilus induce IL-12 and IFN-gamma production. World J Gastroenterol (2008) 1.08

Control of T helper cell differentiation through cytokine receptor inclusion in the immunological synapse. J Exp Med (2009) 1.08

The Axl/Gas6 pathway is required for optimal cytokine signaling during human natural killer cell development. Blood (2008) 1.07

Kruppel-like transcription factor 6 regulates inflammatory macrophage polarization. J Biol Chem (2014) 1.07

Treatment of monocytes with interleukin (IL)-12 plus IL-18 stimulates survival, differentiation and the production of CXC chemokine ligands (CXCL)8, CXCL9 and CXCL10. Clin Exp Immunol (2006) 1.05

Opposing actions of IL-2 and IL-21 on Th9 differentiation correlate with their differential regulation of BCL6 expression. Proc Natl Acad Sci U S A (2014) 1.05

Stochastic cytokine expression induces mixed T helper cell States. PLoS Biol (2013) 1.04

The innate pulmonary granuloma: characterization and demonstration of dendritic cell recruitment and function. Am J Pathol (2004) 1.03

Development of allergen-induced airway inflammation in the absence of T-bet regulation is dependent on IL-17. J Immunol (2009) 1.01

Excessive expression of Txk, a member of the Tec family of tyrosine kinases, contributes to excessive Th1 cytokine production by T lymphocytes in patients with Behcet's disease. Clin Exp Immunol (2005) 1.01

Pre-assembly of STAT4 with the human IFN-alpha/beta receptor-2 subunit is mediated by the STAT4 N-domain. Mol Immunol (2006) 1.01

T-bet is required for protection against vaccinia virus infection. J Virol (2005) 1.00

Type I interferon suppresses de novo virus-specific CD4 Th1 immunity during an established persistent viral infection. Proc Natl Acad Sci U S A (2014) 0.99

Conditional Stat1 ablation reveals the importance of interferon signaling for immunity to Listeria monocytogenes infection. PLoS Pathog (2012) 0.99

Facilitation of Th1-mediated immune response by prostaglandin E receptor EP1. J Exp Med (2007) 0.99

Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science (2004) 19.08

XBP-1 regulates a subset of endoplasmic reticulum resident chaperone genes in the unfolded protein response. Mol Cell Biol (2003) 11.17

XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease. Cell (2008) 8.43

Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system. Cell (2007) 8.42

Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells. Science (2002) 8.34

Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1. Nat Immunol (2003) 7.06

Systemically dispersed innate IL-13-expressing cells in type 2 immunity. Proc Natl Acad Sci U S A (2010) 6.78

XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation. Immunity (2004) 6.72

T-bet regulates the terminal maturation and homeostasis of NK and Valpha14i NKT cells. Immunity (2004) 6.43

Regulation of hepatic lipogenesis by the transcription factor XBP1. Science (2008) 6.02

Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis. J Exp Med (2004) 5.13

Homeostasis and inflammation in the intestine. Cell (2010) 4.60

TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages. Nat Immunol (2010) 4.56

Enterobacteriaceae act in concert with the gut microbiota to induce spontaneous and maternally transmitted colitis. Cell Host Microbe (2010) 4.54

Proteasome inhibitors disrupt the unfolded protein response in myeloma cells. Proc Natl Acad Sci U S A (2003) 4.47

Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha. Science (2006) 4.46

T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes. Nat Immunol (2002) 4.38

The endoplasmic reticulum stress response in immunity and autoimmunity. Nat Rev Immunol (2008) 4.09

Regulation of NF-kappaB, Th activation, and autoinflammation by the forkhead transcription factor Foxo3a. Immunity (2004) 3.98

XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands. EMBO J (2005) 3.92

Development of spontaneous airway changes consistent with human asthma in mice lacking T-bet. Science (2002) 3.91

NFATc1 balances quiescence and proliferation of skin stem cells. Cell (2008) 3.81

Oocyte-specific deletion of Pten causes premature activation of the primordial follicle pool. Science (2008) 3.80

Osteopontin expression is essential for interferon-alpha production by plasmacytoid dendritic cells. Nat Immunol (2006) 3.70

T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3. Science (2005) 3.65

XBP1 is essential for survival under hypoxic conditions and is required for tumor growth. Cancer Res (2004) 3.24

Antigen-driven effector CD8 T cell function regulated by T-bet. Proc Natl Acad Sci U S A (2003) 3.23

The role of Th1/Th2 polarization in mucosal immunity. Nat Med (2002) 3.19

Interferon regulatory factor 4 (IRF4) interacts with NFATc2 to modulate interleukin 4 gene expression. J Exp Med (2002) 3.16

Critical roles for transcription factor GATA-3 in thymocyte development. Immunity (2003) 3.15

Recent developments in the transcriptional regulation of cytolytic effector cells. Nat Rev Immunol (2004) 3.14

BAX inhibitor-1 is a negative regulator of the ER stress sensor IRE1alpha. Mol Cell (2009) 3.07

XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy. Genes Dev (2009) 3.03

T-bet is required for optimal proinflammatory CD4+ T-cell trafficking. Blood (2005) 2.95

Regulation of adult bone mass by the zinc finger adapter protein Schnurri-3. Science (2006) 2.70

T-bet represses T(H)17 differentiation by preventing Runx1-mediated activation of the gene encoding RORγt. Nat Immunol (2010) 2.68

Divergent expression patterns of IL-4 and IL-13 define unique functions in allergic immunity. Nat Immunol (2011) 2.67

Regulation of homeostatic chemokine expression and cell trafficking during immune responses. Science (2007) 2.67

T-bet regulates IgG class switching and pathogenic autoantibody production. Proc Natl Acad Sci U S A (2002) 2.63

The unfolded protein response: integrating stress signals through the stress sensor IRE1α. Physiol Rev (2011) 2.50

Fine-tuning of the unfolded protein response: Assembling the IRE1alpha interactome. Mol Cell (2009) 2.47

Inflammatory arthritis requires Foxo3a to prevent Fas ligand-induced neutrophil apoptosis. Nat Med (2005) 2.43

T-bet is required for optimal production of IFN-gamma and antigen-specific T cell activation by dendritic cells. Proc Natl Acad Sci U S A (2003) 2.34

NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism. J Clin Invest (2008) 2.29

IL-18 and IL-33 elicit Th2 cytokines from basophils via a MyD88- and p38alpha-dependent pathway. J Leukoc Biol (2009) 2.29

A novel role of CD4 Th17 cells in mediating cardiac allograft rejection and vasculopathy. J Exp Med (2008) 2.26

Arginine methylation of NIP45 modulates cytokine gene expression in effector T lymphocytes. Mol Cell (2004) 2.20

The X-box binding protein-1 transcription factor is required for plasma cell differentiation and the unfolded protein response. Immunol Rev (2003) 2.20

The transcription factor XBP-1 is essential for the development and survival of dendritic cells. J Exp Med (2007) 2.12

Signaling pathways in Th2 development. Immunol Rev (2004) 2.10

Bifidobacterium animalis subsp. lactis fermented milk product reduces inflammation by altering a niche for colitogenic microbes. Proc Natl Acad Sci U S A (2010) 2.10

T-bet in disease. Nat Immunol (2011) 2.09

Failed efficacy of soluble human CD83-Ig in allogeneic mixed lymphocyte reactions and experimental autoimmune encephalomyelitis: implications for a lack of therapeutic potential. Immunol Lett (2007) 2.05

Abatacept in relapsing polychondritis. Ann Rheum Dis (2013) 2.01

The p38 MAPK pathway is essential for skeletogenesis and bone homeostasis in mice. J Clin Invest (2010) 1.98

Differential effects of unfolded protein response pathways on axon injury-induced death of retinal ganglion cells. Neuron (2012) 1.97

Colitis-associated colorectal cancer driven by T-bet deficiency in dendritic cells. Cancer Cell (2009) 1.95

The unfolded protein response element IRE1α senses bacterial proteins invading the ER to activate RIG-I and innate immune signaling. Cell Host Microbe (2013) 1.91

Silencing of lipid metabolism genes through IRE1α-mediated mRNA decay lowers plasma lipids in mice. Cell Metab (2012) 1.90

T-bet controls autoaggressive CD8 lymphocyte responses in type 1 diabetes. J Exp Med (2004) 1.88

Cdh1 regulates osteoblast function through an APC/C-independent modulation of Smurf1. Mol Cell (2011) 1.87

The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes. Proc Natl Acad Sci U S A (2009) 1.86

T-bet-dependent expression of osteopontin contributes to T cell polarization. Proc Natl Acad Sci U S A (2005) 1.83

T-bet deficiency reduces atherosclerosis and alters plaque antigen-specific immune responses. Proc Natl Acad Sci U S A (2005) 1.82

Transcription: tantalizing times for T cells. Cell (2002) 1.82

Pharmacologic targeting of a stem/progenitor population in vivo is associated with enhanced bone regeneration in mice. J Clin Invest (2008) 1.81

Excess of rare variants in non-genome-wide association study candidate genes in patients with hypertriglyceridemia. Circ Cardiovasc Genet (2011) 1.78

Protein folding stress in neurodegenerative diseases: a glimpse into the ER. Curr Opin Cell Biol (2011) 1.77

A role for the immunological synapse in lineage commitment of CD4 lymphocytes. Nature (2004) 1.77

Calcineurin regulates innate antifungal immunity in neutrophils. J Exp Med (2010) 1.76

Constraints in antigen presentation severely restrict T cell recognition of the allogeneic fetus. J Clin Invest (2007) 1.75

Extensive pancreas regeneration following acinar-specific disruption of Xbp1 in mice. Gastroenterology (2011) 1.72

XBP1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell development. J Exp Med (2009) 1.71

Type I IFN protects against murine lupus. J Immunol (2004) 1.71

Maintenance of mouse trophoblast stem cell proliferation by TGF-beta/activin. Dev Biol (2004) 1.71

The transcription factor cyclic AMP-responsive element-binding protein H regulates triglyceride metabolism. Nat Med (2011) 1.70

T-bet: a bridge between innate and adaptive immunity. Nat Rev Immunol (2013) 1.70

Fluorescent in vivo detection reveals that IgE(+) B cells are restrained by an intrinsic cell fate predisposition. Immunity (2012) 1.70

T-bet, a T-cell-associated transcription factor, is expressed in a subset of B-cell lymphoproliferative disorders. Am J Clin Pathol (2004) 1.70

The gene encoding early growth response 2, a target of the transcription factor NFAT, is required for the development and maturation of natural killer T cells. Nat Immunol (2009) 1.66

IL-2 production in developing Th1 cells is regulated by heterodimerization of RelA and T-bet and requires T-bet serine residue 508. J Exp Med (2005) 1.64

NFATc1 and NFATc2 repress spontaneous osteoarthritis. Proc Natl Acad Sci U S A (2013) 1.61

Unfolded protein response transcription factor XBP-1 does not influence prion replication or pathogenesis. Proc Natl Acad Sci U S A (2008) 1.60

Dual and opposing roles of the unfolded protein response regulated by IRE1alpha and XBP1 in proinsulin processing and insulin secretion. Proc Natl Acad Sci U S A (2011) 1.59

Regulation of innate immunity by signaling pathways emerging from the endoplasmic reticulum. Curr Opin Immunol (2010) 1.57

Toll-like receptor 9 signaling protects against murine lupus. Arthritis Rheum (2006) 1.56

Dissociation of inositol-requiring enzyme (IRE1α)-mediated c-Jun N-terminal kinase activation from hepatic insulin resistance in conditional X-box-binding protein-1 (XBP1) knock-out mice. J Biol Chem (2011) 1.55

T-bet, a T cell-associated transcription factor, is expressed in Hodgkin's lymphoma. Hum Pathol (2005) 1.52

SH2D1A regulates T-dependent humoral autoimmunity. J Exp Med (2004) 1.51

NFATc2 and NFATc3 regulate T(H)2 differentiation and modulate TCR-responsiveness of naïve T(H)cells. Nat Immunol (2001) 1.51

Administration of BMP2/7 in utero partially reverses Rubinstein-Taybi syndrome-like skeletal defects induced by Pdk1 or Cbp mutations in mice. J Clin Invest (2011) 1.50

Transcription factor T-bet regulates inflammatory arthritis through its function in dendritic cells. J Clin Invest (2006) 1.49

TAK1 is an essential regulator of BMP signalling in cartilage. EMBO J (2009) 1.46

Modulation of Th1 activation and inflammation by the NF-kappaB repressor Foxj1. Science (2004) 1.46

Pillars article: A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell. 2000. 100: 655-669. J Immunol (2015) 1.44

IL-23 receptor regulates unconventional IL-17-producing T cells that control bacterial infections. J Immunol (2010) 1.43

Increased susceptibility of mice lacking T-bet to infection with Mycobacterium tuberculosis correlates with increased IL-10 and decreased IFN-gamma production. J Immunol (2005) 1.41

Transcription factor T-bet regulates skin sclerosis through its function in innate immunity and via IL-13. Proc Natl Acad Sci U S A (2007) 1.39