Published in J Biol Chem on October 27, 2011
Bacterial pathogens activate a common inflammatory pathway through IFNλ regulation of PDCD4. PLoS Pathog (2013) 0.94
Targeting the eIF4A RNA helicase blocks translation of the MUC1-C oncoprotein. Oncogene (2012) 0.92
Reversible induction of translational isoforms of p53 in glucose deprivation. Cell Death Differ (2015) 0.88
eIF4AIII enhances translation of nuclear cap-binding complex-bound mRNAs by promoting disruption of secondary structures in 5'UTR. Proc Natl Acad Sci U S A (2014) 0.86
Loss of PDCD4 contributes to enhanced chemoresistance in Glioblastoma multiforme through de-repression of Bcl-xL translation. Oncotarget (2013) 0.86
Tumor suppressor gene PDCD4 negatively regulates autophagy by inhibiting the expression of autophagy-related gene ATG5. Autophagy (2013) 0.85
Tumor suppressor PDCD4 inhibits NF-κB-dependent transcription in human glioblastoma cells by direct interaction with p65. Carcinogenesis (2014) 0.84
An evolutionarily conserved interaction of tumor suppressor protein Pdcd4 with the poly(A)-binding protein contributes to translation suppression by Pdcd4. Nucleic Acids Res (2014) 0.83
Programmed cell death-4 deficiency prevents diet-induced obesity, adipose tissue inflammation, and insulin resistance. Diabetes (2013) 0.83
Tumor suppressor protein Pdcd4 interacts with Daxx and modulates the stability of Daxx and the Hipk2-dependent phosphorylation of p53 at serine 46. Oncogenesis (2013) 0.82
Translation, Pdcd4 and eIF4A. Oncoscience (2015) 0.81
Translational Control Protein 80 Stimulates IRES-Mediated Translation of p53 mRNA in Response to DNA Damage. Biomed Res Int (2015) 0.78
ERK8 is a novel HuR kinase that regulates tumour suppressor PDCD4 through a miR-21 dependent mechanism. Oncotarget (2016) 0.78
Differential effects of PDCD4 depletion on protein synthesis in myoblast and myotubes. BMC Cell Biol (2014) 0.78
Length variants of the 5' untranslated region of p53 mRNA and their impact on the efficiency of translation initiation of p53 and its N-truncated isoform ΔNp53. RNA Biol (2013) 0.78
Integrative analysis of differential miRNA and functional study of miR-21 by seed-targeting inhibition in multiple myeloma cells in response to berberine. BMC Syst Biol (2014) 0.77
p53 regulation upon genotoxic stress: intricacies and complexities. Mol Cell Oncol (2014) 0.76
miR-181b functions as an oncomiR in colorectal cancer by targeting PDCD4. Protein Cell (2016) 0.76
Targeting IRES-Mediated p53 Synthesis for Cancer Diagnosis and Therapeutics. Int J Mol Sci (2017) 0.75
Depletion of the mRNA translation initiation inhibitor, programmed cell death protein 4 (PDCD4), impairs L6 myotube formation. Physiol Rep (2017) 0.75
Live or let die: the cell's response to p53. Nat Rev Cancer (2002) 15.06
Regulation of translation initiation in eukaryotes: mechanisms and biological targets. Cell (2009) 14.51
p53 in health and disease. Nat Rev Mol Cell Biol (2007) 11.33
Role of autophagy in cancer. Nat Rev Cancer (2007) 10.88
MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer. Oncogene (2007) 10.79
The p53 pathway: positive and negative feedback loops. Oncogene (2005) 9.75
Modes of p53 regulation. Cell (2009) 9.31
S6K1- and betaTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth. Science (2006) 5.94
Cytoplasmic functions of the tumour suppressor p53. Nature (2009) 5.23
p53 and metabolism. Nat Rev Cancer (2009) 5.05
MicroRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene. Oncogene (2008) 4.43
MicroRNA-125b is a novel negative regulator of p53. Genes Dev (2009) 4.43
RNA-binding protein HuR enhances p53 translation in response to ultraviolet light irradiation. Proc Natl Acad Sci U S A (2003) 4.34
Regulation of p53 translation and induction after DNA damage by ribosomal protein L26 and nucleolin. Cell (2005) 4.16
The transformation suppressor Pdcd4 is a novel eukaryotic translation initiation factor 4A binding protein that inhibits translation. Mol Cell Biol (2003) 3.90
p53: new roles in metabolism. Trends Cell Biol (2007) 2.69
Negative feedback regulation of wild-type p53 biosynthesis. EMBO J (1995) 2.52
Mdm2 regulates p53 mRNA translation through inhibitory interactions with ribosomal protein L26. Mol Cell (2008) 2.46
A novel function of the MA-3 domains in transformation and translation suppressor Pdcd4 is essential for its binding to eukaryotic translation initiation factor 4A. Mol Cell Biol (2004) 2.38
Differentially expressed protein Pdcd4 inhibits tumor promoter-induced neoplastic transformation. Proc Natl Acad Sci U S A (1999) 2.19
Involvement of programmed cell death 4 in transforming growth factor-beta1-induced apoptosis in human hepatocellular carcinoma. Oncogene (2006) 2.10
Isolation of a novel mouse gene MA-3 that is induced upon programmed cell death. Gene (1995) 2.05
Loss of PDCD4 expression in human lung cancer correlates with tumour progression and prognosis. J Pathol (2003) 2.04
Pdcd4 suppresses tumor phenotype in JB6 cells by inhibiting AP-1 transactivation. Oncogene (2003) 1.87
5'-3'-UTR interactions regulate p53 mRNA translation and provide a target for modulating p53 induction after DNA damage. Genes Dev (2010) 1.64
Two internal ribosome entry sites mediate the translation of p53 isoforms. EMBO Rep (2006) 1.64
Induction of PDCD4 tumor suppressor gene expression by RAR agonists, antiestrogen and HER-2/neu antagonist in breast cancer cells. Evidence for a role in apoptosis. Oncogene (2004) 1.63
Tumor suppressor Pdcd4 inhibits invasion/intravasation and regulates urokinase receptor (u-PAR) gene expression via Sp-transcription factors. Oncogene (2007) 1.62
PDCD4 inhibits translation initiation by binding to eIF4A using both its MA3 domains. Proc Natl Acad Sci U S A (2008) 1.52
Structural basis for inhibition of translation by the tumor suppressor Pdcd4. Mol Cell Biol (2006) 1.49
Transformation suppressor protein Pdcd4 interferes with JNK-mediated phosphorylation of c-Jun and recruitment of the coactivator p300 by c-Jun. Oncogene (2004) 1.47
The identification of an internal ribosomal entry site in the 5'-untranslated region of p53 mRNA provides a novel mechanism for the regulation of its translation following DNA damage. Oncogene (2006) 1.41
MicroRNA 125a and its regulation of the p53 tumor suppressor gene. FEBS Lett (2009) 1.40
Structural basis for translational inhibition by the tumour suppressor Pdcd4. EMBO J (2009) 1.38
siRNA-mediated knockdown of Pdcd4 expression causes upregulation of p21(Waf1/Cip1) expression. Oncogene (2008) 1.36
Structure of the C-terminal MA-3 domain of the tumour suppressor protein Pdcd4 and characterization of its interaction with eIF4A. Oncogene (2007) 1.28
Crystal structure of the eIF4A-PDCD4 complex. Proc Natl Acad Sci U S A (2009) 1.23
The p53 target Wig-1 regulates p53 mRNA stability through an AU-rich element. Proc Natl Acad Sci U S A (2009) 1.17
Pdcd4 directly binds the coding region of c-myb mRNA and suppresses its translation. Oncogene (2011) 1.12
Regulation of tumor suppressor p53 at the RNA level. J Mol Med (Berl) (2010) 1.08
Disruption of the Pdcd4 tumor suppressor gene in chicken DT40 cells reveals its role in the DNA-damage response. Oncogene (2009) 0.92
A novel role for IGF-1R in p53-mediated apoptosis through translational modulation of the p53-Mdm2 feedback loop. J Cell Biol (2007) 0.92
Daxx is a transcriptional repressor of CCAAT/enhancer-binding protein beta. J Biol Chem (2009) 0.90
Structure of the tandem MA-3 region of Pdcd4 protein and characterization of its interactions with eIF4A and eIF4G: molecular mechanisms of a tumor suppressor. J Biol Chem (2011) 0.88
Association of Tumor Suppressor Protein Pdcd4 With Ribosomes Is Mediated by Protein-Protein and Protein-RNA Interactions. Genes Cancer (2010) 0.84
Transformation suppressor protein Pdcd4 interferes with JNK-mediated phosphorylation of c-Jun and recruitment of the coactivator p300 by c-Jun. Oncogene (2004) 1.47
Chemical composition, antifungal and antiaflatoxigenic activities of Ocimum sanctum L. essential oil and its safety assessment as plant based antimicrobial. Food Chem Toxicol (2009) 1.38
The transformation suppressor protein Pdcd4 shuttles between nucleus and cytoplasm and binds RNA. Oncogene (2003) 1.35
Recruitment of p300 by C/EBPbeta triggers phosphorylation of p300 and modulates coactivator activity. EMBO J (2003) 1.29
A population-based study of neonatal mortality and maternal care utilization in the Indian state of Bihar. BMC Pregnancy Childbirth (2014) 1.11
Protein mass-modulated effects in the catalytic mechanism of dihydrofolate reductase: beyond promoting vibrations. J Am Chem Soc (2014) 1.04
v-Myb mediates cooperation of a cell-specific enhancer with the mim-1 promoter. Mol Cell Biol (2005) 0.98
A test of individuality of human external ear pattern: its application in the field of personal identification. Forensic Sci Int (2008) 0.95
DEC-205-mediated internalization of HIV-1 results in the establishment of silent infection in renal tubular cells. J Am Soc Nephrol (2007) 0.95
Mutant GBA1 expression and synucleinopathy risk: first insights from cellular and mouse models. Neurodegener Dis (2012) 0.94
NMR assignment and secondary structure determination of the C-terminal MA-3 domain of the tumour suppressor protein Pdcd4. J Biomol NMR (2006) 0.94
C/EBPbeta induces chromatin opening at a cell-type-specific enhancer. Mol Cell Biol (2008) 0.94
Efficacy of Lippia alba (Mill.) N.E. Brown essential oil and its monoterpene aldehyde constituents against fungi isolated from some edible legume seeds and aflatoxin B1 production. Int J Food Microbiol (2009) 0.92
Efficacy of chemically characterized Piper betle L. essential oil against fungal and aflatoxin contamination of some edible commodities and its antioxidant activity. Int J Food Microbiol (2010) 0.91
Survey of renewable chemicals produced from lignocellulosic biomass during ionic liquid pretreatment. Biotechnol Biofuels (2013) 0.91
The cooperation of B-Myb with the coactivator p300 is orchestrated by cyclins A and D1. Oncogene (2004) 0.91
Anthropometry of the normal human auricle: a study of adult Indian men. Aesthetic Plast Surg (2007) 0.90
Daxx is a transcriptional repressor of CCAAT/enhancer-binding protein beta. J Biol Chem (2009) 0.90
A Drosophila systems model of pentylenetetrazole induced locomotor plasticity responsive to antiepileptic drugs. BMC Syst Biol (2009) 0.89
Structure of the tandem MA-3 region of Pdcd4 protein and characterization of its interactions with eIF4A and eIF4G: molecular mechanisms of a tumor suppressor. J Biol Chem (2011) 0.88
Mushroom body miscellanea: transgenic Drosophila strains expressing anatomical and physiological sensor proteins in Kenyon cells. Front Neural Circuits (2013) 0.87
Natural sesquiterpene lactones as inhibitors of Myb-dependent gene expression: structure-activity relationships. Eur J Med Chem (2013) 0.87
Regulation of the cyclin D1 and cyclin A1 promoters by B-Myb is mediated by Sp1 binding sites. Gene (2005) 0.86
Understanding changes in lignin of Panicum virgatum and Eucalyptus globulus as a function of ionic liquid pretreatment. Bioresour Technol (2012) 0.86
Study of accuracy of colposcopy in VIA and HPV detection-based cervical cancer screening program. Aust N Z J Obstet Gynaecol (2014) 0.86
Efficacy of essential oils of Lippia alba (Mill.) N.E. Brown and Callistemon lanceolatus (Sm.) Sweet and their major constituents on mortality, oviposition and feeding behaviour of pulse beetle, Callosobruchus chinensis L. J Sci Food Agric (2011) 0.86
Synthesis and evaluation of small libraries of triazolylmethoxy chalcones, flavanones and 2-aminopyrimidines as inhibitors of mycobacterial FAS-II and PknG. Bioorg Med Chem (2012) 0.85
Association of Tumor Suppressor Protein Pdcd4 With Ribosomes Is Mediated by Protein-Protein and Protein-RNA Interactions. Genes Cancer (2010) 0.84
Letter to the editor: Characterization of a Grapevine leafroll-associated virus 3 from India showing incongruence in its phylogeny. Virus Genes (2012) 0.84
Serum magnesium concentration is a significant predictor of mortality in peritoneal dialysis patients. Adv Perit Dial (2014) 0.83
Disruption of B-myb in DT40 cells reveals novel function for B-Myb in the response to DNA-damage. Oncogene (2005) 0.82
Myb-induced chromatin remodeling at a dual enhancer/promoter element involves non-coding rna transcription and is disrupted by oncogenic mutations of v-myb. J Biol Chem (2009) 0.82
Safety assessment of Zanthoxylum alatum Roxb. essential oil, its antifungal, antiaflatoxin, antioxidant activity and efficacy as antimicrobial in preservation of Piper nigrum L. fruits. Int J Food Microbiol (2011) 0.81
In vivo activity of thiophene-containing trisubstituted methanes against acute and persistent infection of non-tubercular Mycobacterium fortuitum in a murine infection model. J Antimicrob Chemother (2012) 0.81
Aryl aryl methyl thio arenes prevent multidrug-resistant malaria in mouse by promoting oxidative stress in parasites. Free Radic Biol Med (2012) 0.81
Identification of a Myb-responsive enhancer of the chicken C/EBPbeta gene. Oncogene (2004) 0.80
PRMT4 is a novel coactivator of c-Myb-dependent transcription in haematopoietic cell lines. PLoS Genet (2013) 0.80
Detection of transgenerational spermatogenic inheritance of adult male acquired CNS gene expression characteristics using a Drosophila systems model. PLoS One (2009) 0.80
Identification and characterization of the Myb-inducible promoter of the chicken adenosine receptor 2B gene. Oncogene (2002) 0.80
Interaction and cooperation of the CCAAT-box enhancer-binding protein β (C/EBPβ) with the homeodomain-interacting protein kinase 2 (Hipk2). J Biol Chem (2013) 0.80
Safety profile assessment and efficacy of chemically characterized Cinnamomum glaucescens essential oil against storage fungi, insect, aflatoxin secretion and as antioxidant. Food Chem Toxicol (2012) 0.79
B-Myb promotes S-phase independently of its sequence-specific DNA binding activity and interacts with polymerase delta-interacting protein 1 (Pdip1). Cell Cycle (2012) 0.79
Genetic polymorphisms of GSTM1, GSTT1 and GSTP1 and susceptibility to DNA damage in workers occupationally exposed to organophosphate pesticides. Mutat Res (2011) 0.79
Oncogenic point mutations in the Myb DNA-binding domain alter the DNA-binding properties of Myb at a physiological target gene. Nucleic Acids Res (2007) 0.79
Targeted disruption of c-myb in the chicken pre B-cell line DT40. Oncogene (2002) 0.79
Infection of tomato leaf curl New Delhi virus (ToLCNDV), a bipartite begomovirus with betasatellites, results in enhanced level of helper virus components and antagonistic interaction between DNA B and betasatellites. Appl Microbiol Biotechnol (2013) 0.79
Transactivation mediated by B-Myb is dependent on TAF(II)250. Oncogene (2003) 0.79
Design, synthesis and biological evaluation of 1,3,4-oxadiazole derivatives. Eur J Med Chem (2010) 0.78
Biochemical characterization of alanine racemase--a spore protein produced by Bacillus anthracis. BMB Rep (2009) 0.78
Maladaptation of critical cellular functions in asthma: bioinformatic analysis. Physiol Genomics (2009) 0.78
Resonance assignment and secondary structure of the middle MA-3 domain and complete tandem MA-3 region of the tumour suppressor protein Pdcd4. Biomol NMR Assign (2009) 0.78
Experimental IR and Raman spectra and quantum chemical studies of molecular structures, conformers and vibrational characteristics of L-ascorbic acid and its anion and cation. Spectrochim Acta A Mol Biomol Spectrosc (2011) 0.78
Genomics of helper component proteinase reveals effective strategy for papaya ringspot virus resistance. Mol Biotechnol (2009) 0.77
Behavior of RNAi suppressor protein 2b of Cucumber mosaic virus in planta in presence and absence of virus. Virus Genes (2008) 0.77
Effect of maternal fatness on fetal steroids and semi-quantitative real-time PCR expression of receptor genes in sheep. Anim Reprod Sci (2008) 0.77
Role of genetic polymorphisms of CYP1A1, CYP3A5, CYP2C9, CYP2D6, and PON1 in the modulation of DNA damage in workers occupationally exposed to organophosphate pesticides. Toxicol Appl Pharmacol (2011) 0.77
Influence of CYP2C9, GSTM1, GSTT1 and NAT2 genetic polymorphisms on DNA damage in workers occupationally exposed to organophosphate pesticides. Mutat Res (2011) 0.77
Proliferation and decidualization of endometrial stromal cells during embryo-attachment stage in bonnet monkeys (Macaca radiata). Cell Tissue Res (2015) 0.76
The glioma-amplified sequence 41 gene (GAS41) is a direct Myb target gene. Nucleic Acids Res (2004) 0.76
Interaction of the transactivation domain of B-Myb with the TAZ2 domain of the coactivator p300: molecular features and properties of the complex. PLoS One (2012) 0.76
A dual activation mechanism for Myb-responsive genes in myelomonocytic cells. Blood Cells Mol Dis (2007) 0.76
Anti-cholinergic alkaloids as potential therapeutic agents for Alzheimer's disease: an in silico approach. Indian J Biochem Biophys (2013) 0.76
Gender differences in a Drosophila transcriptomic model of chronic pentylenetetrazole induced behavioral deficit. PLoS One (2009) 0.75
Treponema pallidum putative novel drug target identification and validation: rethinking syphilis therapeutics with plant-derived terpenoids. OMICS (2015) 0.75
Oral tuberculosis involving maxillary gingiva. Natl J Maxillofac Surg (2011) 0.75
Adjustable recessions in horizontal comitant strabismus: A pilot study. Indian J Ophthalmol (2015) 0.75
The promoter regions of the Myb-regulated Adora2B and Mcm4 genes co-localize with origins of DNA replication. BMC Mol Biol (2007) 0.75
Re: Sutureless 23-gauge versus 20-gauge vitrectomy with silicone oil injection in rhegmatogenous retinal detachment. Retina (2012) 0.75
Clinicopathologic Analysis of Stable and Unstable Vitiligo: A Study of 66 Cases. Am J Dermatopathol (2016) 0.75
Oro-facial granulomatosis--a case report. Indian J Tuberc (2012) 0.75
Efficacy of organophosphorus derivatives containing chalcones/chalcone semicarbazones against fungal pathogens of sugarcane. Met Based Drugs (2002) 0.75
Dialysis membrane-induced oxidative stress: role of heme oxygenase-1. Nephron Exp Nephrol (2006) 0.75
Structural modeling and simulation studies of human cyclooxygenase (COX) isozymes with selected terpenes: implications in drug designing and development. Comput Biol Med (2013) 0.75
Investigating Drug Repositioning Approach to Design Novel Prodrugs for Colon-Specific Release of Fexofenadine for Ulcerative Colitis. Curr Drug Deliv (2016) 0.75
DNA Folding Transition in Presence of Naphthylhydroxamic Acids as Revealed by Fluorescence Microscopic Single Molecule Observation Method. J Fluoresc (2016) 0.75
Cloning and expression of a small heat and salt tolerant protein (Hsp22) from Chaetomium globosum. Indian J Exp Biol (2012) 0.75
Double Augmented Vertical Rectus Transposition for Large-Angle Esotropia Due to Sixth Nerve Palsy. J Pediatr Ophthalmol Strabismus (2016) 0.75
Burkholderia ginsengiterrae sp. nov. and Burkholderia panaciterrae sp. nov., antagonistic bacteria against root rot pathogen Cylindrocarpon destructans, isolated from ginseng soil. Arch Microbiol (2014) 0.75
Analysis of DNase I-hypersensitive sites in the chromatin of the chicken C/EBPbeta gene reveals multiple cis-regulatory elements. DNA Cell Biol (2003) 0.75
Comparative Effectiveness of Ultrasonography, 99mTc-Sestamibi, and 18F-Fluorocholine PET/CT in Detecting Parathyroid Adenomas in Patients With Primary Hyperparathyroidism. Clin Nucl Med (2017) 0.75
Relationship of Normalized Protein Catabolic Rate with Nutrition Status and Long-Term Survival in Peritoneal Dialysis Patients. Adv Perit Dial (2015) 0.75
Advances in development of a contraceptive vaccine against human chorionic gonadotropin. Expert Opin Biol Ther (2015) 0.75
Association of metabolic syndrome and periodontal disease in an Indian population. J Int Acad Periodontol (2014) 0.75
The management of congenital superior conjunctival fornix prolapse. Orbit (2013) 0.75