Published in Genet Epidemiol on January 01, 2011
A dual-clustering framework for association screening with whole genome sequencing data and longitudinal traits. BMC Proc (2014) 1.41
Lessons learned from Genetic Analysis Workshop 17: transitioning from genome-wide association studies to whole-genome statistical genetic analysis. Genet Epidemiol (2011) 1.34
PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet (2007) 209.92
Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet (2006) 115.71
Methods for detecting associations with rare variants for common diseases: application to analysis of sequence data. Am J Hum Genet (2008) 26.79
An evaluation of statistical approaches to rare variant analysis in genetic association studies. Genet Epidemiol (2010) 10.54
Genetic Analysis Workshop 17 mini-exome simulation. BMC Proc (2011) 9.16
Statistical analysis of rare sequence variants: an overview of collapsing methods. Genet Epidemiol (2011) 6.18
A primer on learning in Bayesian networks for computational biology. PLoS Comput Biol (2007) 2.60
Brief review of regression-based and machine learning methods in genetic epidemiology: the Genetic Analysis Workshop 17 experience. Genet Epidemiol (2011) 2.25
Overrepresentation of rare variants in a specific ethnic group may confuse interpretation of association analyses. Hum Mol Genet (2006) 1.84
Penalized methods for bi-level variable selection. Stat Interface (2009) 1.82
Lessons learned from Genetic Analysis Workshop 17: transitioning from genome-wide association studies to whole-genome statistical genetic analysis. Genet Epidemiol (2011) 1.34
Association screening for genes with multiple potentially rare variants: an inverse-probability weighted clustering approach. BMC Proc (2011) 1.10
A LASSO-based approach to analyzing rare variants in genetic association studies. BMC Proc (2011) 0.98
Stratify or adjust? Dealing with multiple populations when evaluating rare variants. BMC Proc (2011) 0.89
Digging into the extremes: a useful approach for the analysis of rare variants with continuous traits? BMC Proc (2011) 0.88
Assessing the impact of missing genotype data in rare variant association analysis. BMC Proc (2011) 0.84
Novel tree-based method to generate markers from rare variant data. BMC Proc (2011) 0.82
Identification of multiple rare variants associated with a disease. BMC Proc (2011) 0.82
Detection of rare variant effects in association studies: extreme values, iterative regression, and a hybrid approach. BMC Proc (2011) 0.82
Performance of random forests and logic regression methods using mini-exome sequence data. BMC Proc (2011) 0.82
Application of Bayesian network structure learning to identify causal variant SNPs from resequencing data. BMC Proc (2011) 0.82
Detection of rare functional variants using group ISIS. BMC Proc (2011) 0.81
Genome-wide case-control study in GAW17 using coalesced rare variants. BMC Proc (2011) 0.80
Are quantitative trait-dependent sampling designs cost-effective for analysis of rare and common variants? BMC Proc (2011) 0.79
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements. Nat Biotechnol (2006) 30.90
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
Genome-wide atlas of gene expression in the adult mouse brain. Nature (2006) 28.02
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet (2008) 22.35
Human genome sequencing using unchained base reads on self-assembling DNA nanoarrays. Science (2009) 21.24
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
Genome-wide detection and characterization of positive selection in human populations. Nature (2007) 17.27
Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet (2008) 15.94
Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases. Cancer Cell (2011) 11.44
Meta-analysis and imputation refines the association of 15q25 with smoking quantity. Nat Genet (2010) 8.55
Extended antiretroviral prophylaxis to reduce breast-milk HIV-1 transmission. N Engl J Med (2008) 8.19
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet (2010) 7.94
The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models. Nat Biotechnol (2010) 7.08
A first-generation linkage disequilibrium map of human chromosome 22. Nature (2002) 7.03
FaST linear mixed models for genome-wide association studies. Nat Methods (2011) 6.52
Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. Nat Genet (2010) 6.49
The complete genome sequence of Francisella tularensis, the causative agent of tularemia. Nat Genet (2005) 6.22
Increasing hospital admission rates for urological complications after transrectal ultrasound guided prostate biopsy. J Urol (2010) 6.01
Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet (2009) 5.81
New loci associated with kidney function and chronic kidney disease. Nat Genet (2010) 5.58
Wnt5a signaling directly affects cell motility and invasion of metastatic melanoma. Cancer Cell (2002) 5.23
Circulating microRNA: a novel potential biomarker for early diagnosis of acute myocardial infarction in humans. Eur Heart J (2010) 5.04
Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations. PLoS Genet (2009) 4.97
Genomic inflation factors under polygenic inheritance. Eur J Hum Genet (2011) 4.89
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nat Genet (2012) 4.73
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Nat Genet (2012) 4.37
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet (2014) 4.13
Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways. Diabetes (2010) 4.07
Genomic alterations in cultured human embryonic stem cells. Nat Genet (2005) 3.89
Identification of seven loci affecting mean telomere length and their association with disease. Nat Genet (2013) 3.87
Acetylation targets the M2 isoform of pyruvate kinase for degradation through chaperone-mediated autophagy and promotes tumor growth. Mol Cell (2011) 3.78
Accurate whole-genome sequencing and haplotyping from 10 to 20 human cells. Nature (2012) 3.74
Letrozole versus clomiphene for infertility in the polycystic ovary syndrome. N Engl J Med (2014) 3.57
Genetic structure of Europeans: a view from the North-East. PLoS One (2009) 3.46
Genetic ablation of solute carrier family 7a3a leads to hepatic steatosis in zebrafish during fasting. Hepatology (2014) 3.40
Statistical methods for testing effects on "maximum lifespan". Mech Ageing Dev (2004) 3.26
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet (2013) 3.25
The Wnt5A/protein kinase C pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition. J Biol Chem (2007) 3.24
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21
Genome-wide association scan for diabetic nephropathy susceptibility genes in type 1 diabetes. Diabetes (2009) 3.16
New gene functions in megakaryopoiesis and platelet formation. Nature (2011) 3.14
Ceramides and other bioactive sphingolipid backbones in health and disease: lipidomic analysis, metabolism and roles in membrane structure, dynamics, signaling and autophagy. Biochim Biophys Acta (2006) 3.10
Clinical classification schemes for predicting hemorrhage: results from the National Registry of Atrial Fibrillation (NRAF). Am Heart J (2006) 3.05
Trajectory of performance status and symptom scores for patients with cancer during the last six months of life. J Clin Oncol (2011) 3.05
Human embryonic stem cells have a unique epigenetic signature. Genome Res (2006) 2.89
Familial and genetic susceptibility to major neonatal morbidities in preterm twins. Pediatrics (2006) 2.86
Optimization of sensing and feedback control for vibration/flutter of rotating disk by PZT actuators via air coupled pressure. Sensors (Basel) (2011) 2.84
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. PLoS Genet (2013) 2.83
An interleukin-21-interleukin-10-STAT3 pathway is critical for functional maturation of memory CD8+ T cells. Immunity (2011) 2.77
FTO genotype is associated with phenotypic variability of body mass index. Nature (2012) 2.77
Inhibition of α-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors. Genes Dev (2012) 2.70
CUBN is a gene locus for albuminuria. J Am Soc Nephrol (2011) 2.70
Structure and function of a transcriptional network activated by the MAPK Hog1. Nat Genet (2008) 2.67
Binding of blood proteins to carbon nanotubes reduces cytotoxicity. Proc Natl Acad Sci U S A (2011) 2.66
Reduction of selection bias in genomewide studies by resampling. Genet Epidemiol (2005) 2.66
Adulthood outcome of tic and obsessive-compulsive symptom severity in children with Tourette syndrome. Arch Pediatr Adolesc Med (2006) 2.62
A genome-wide association meta-analysis identifies new childhood obesity loci. Nat Genet (2012) 2.60
Desmoglein 2 is a receptor for adenovirus serotypes 3, 7, 11 and 14. Nat Med (2010) 2.58
Increasing hospital admission rates for urological complications after transrectal ultrasound guided prostate biopsy. J Urol (2013) 2.53
Up-regulation of mitochondrial activity and acquirement of brown adipose tissue-like property in the white adipose tissue of fsp27 deficient mice. PLoS One (2008) 2.51
Hyaluronan accumulates in demyelinated lesions and inhibits oligodendrocyte progenitor maturation. Nat Med (2005) 2.46
Stratified false discovery control for large-scale hypothesis testing with application to genome-wide association studies. Genet Epidemiol (2006) 2.45
Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans. Diabetes (2010) 2.44
Anatomical traits associated with absorption and mycorrhizal colonization are linked to root branch order in twenty-three Chinese temperate tree species. New Phytol (2008) 2.43
Loss of synchronized retinal phagocytosis and age-related blindness in mice lacking alphavbeta5 integrin. J Exp Med (2004) 2.42
Preoperative anxiety and emergence delirium and postoperative maladaptive behaviors. Anesth Analg (2004) 2.37
Lifelong reduction of LDL-cholesterol related to a common variant in the LDL-receptor gene decreases the risk of coronary artery disease--a Mendelian Randomisation study. PLoS One (2008) 2.37
Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia. Nat Genet (2013) 2.36
A forest-based approach to identifying gene and gene gene interactions. Proc Natl Acad Sci U S A (2007) 2.36
Endoplasmic reticulum stress is important for the manifestations of α-synucleinopathy in vivo. J Neurosci (2012) 2.35
Basal Ganglia volumes in patients with Gilles de la Tourette syndrome. Arch Gen Psychiatry (2003) 2.33
Proliferation of prenatal ultrasonography. CMAJ (2010) 2.33
Methods of the International Tobacco Control (ITC) China Survey. Tob Control (2009) 2.30
Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight. Nat Genet (2010) 2.30
Highly multiplexed single-cell analysis of formalin-fixed, paraffin-embedded cancer tissue. Proc Natl Acad Sci U S A (2013) 2.29
IScore: a risk score to predict death early after hospitalization for an acute ischemic stroke. Circulation (2011) 2.29
Inhibition of hemangiogenesis and lymphangiogenesis after normal-risk corneal transplantation by neutralizing VEGF promotes graft survival. Invest Ophthalmol Vis Sci (2004) 2.27
The exomes of the NCI-60 panel: a genomic resource for cancer biology and systems pharmacology. Cancer Res (2013) 2.27
Postnatal HIV-1 transmission after cessation of infant extended antiretroviral prophylaxis and effect of maternal highly active antiretroviral therapy. J Infect Dis (2009) 2.26
Rare genetic variation at Zea mays crtRB1 increases beta-carotene in maize grain. Nat Genet (2010) 2.25
SNP-based analysis of genetic substructure in the German population. Hum Hered (2006) 2.21
Frequency of gastroenteritis and gastroenteritis-associated mortality with early weaning in HIV-1-uninfected children born to HIV-infected women in Malawi. J Acquir Immune Defic Syndr (2010) 2.19
Inactivation of a novel FGF23 regulator, FAM20C, leads to hypophosphatemic rickets in mice. PLoS Genet (2012) 2.19
A document clustering and ranking system for exploring MEDLINE citations. J Am Med Inform Assoc (2007) 2.18
Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies. J Am Coll Cardiol (2010) 2.17
Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height. Am J Hum Genet (2010) 2.15
A genome-wide association study identifies susceptibility loci for nonsyndromic sagittal craniosynostosis near BMP2 and within BBS9. Nat Genet (2012) 2.12
Socioeconomic status and diagnosed diabetes incidence. Diabetes Res Clin Pract (2005) 2.08
Corneal immunity is mediated by heterogeneous population of antigen-presenting cells. J Leukoc Biol (2003) 2.08