Published in PLoS One on January 18, 2012
Riboswitches for intracellular study of genes involved in Francisella pathogenesis. MBio (2012) 0.84
Regulation of gene expression in diverse cyanobacterial species by using theophylline-responsive riboswitches. Appl Environ Microbiol (2014) 0.83
Regulatory RNAs: charming gene management styles for synthetic biology applications. RNA Biol (2013) 0.82
Using riboswitches to regulate gene expression and define gene function in mycobacteria. Methods Enzymol (2014) 0.79
Opportunities in the design and application of RNA for gene expression control. Nucleic Acids Res (2016) 0.78
The rv1184c locus encodes Chp2, an acyltransferase in Mycobacterium tuberculosis polyacyltrehalose lipid biosynthesis. J Bacteriol (2014) 0.77
Elucidating population-wide mycobacterial replication dynamics at the single-cell level. Microbiology (2016) 0.75
Emerging applications of riboswitches - from antibacterial targets to molecular tools. J Appl Genet (2016) 0.75
Engineering Cyanobacterial Cell Morphology for Enhanced Recovery and Processing of Biomass. Appl Environ Microbiol (2017) 0.75
Benzoic Acid-Inducible Gene Expression in Mycobacteria. PLoS One (2015) 0.75
Ribosomal binding site switching: an effective strategy for high-throughput cloning constructions. PLoS One (2012) 0.75
An IPTG Inducible Conditional Expression System for Mycobacteria. PLoS One (2015) 0.75
Engineering an inducible gene expression system for Bacillus subtilis from a strong constitutive promoter and a theophylline-activated synthetic riboswitch. Microb Cell Fact (2016) 0.75
Characterization of engineered preQ1 riboswitches for inducible gene regulation in mycobacteria. J Bacteriol (2017) 0.75
Regulated Expression Systems for Mycobacteria and Their Applications. Microbiol Spectr (2014) 0.75
Drugs for bad bugs: confronting the challenges of antibacterial discovery. Nat Rev Drug Discov (2006) 15.21
New use of BCG for recombinant vaccines. Nature (1991) 14.40
Evaluation of a nutrient starvation model of Mycobacterium tuberculosis persistence by gene and protein expression profiling. Mol Microbiol (2002) 8.90
Nonreplicating persistence of mycobacterium tuberculosis. Annu Rev Microbiol (2001) 7.05
Controlling gene expression in mycobacteria with anhydrotetracycline and Tet repressor. Nucleic Acids Res (2005) 4.00
The genetics and biochemistry of isoniazid resistance in mycobacterium tuberculosis. Microbes Infect (2000) 3.40
Mycobacterium tuberculosis invasion of macrophages: linking bacterial gene expression to environmental cues. Cell Host Microbe (2007) 3.01
Tetracycline-inducible gene regulation in mycobacteria. Nucleic Acids Res (2005) 2.12
Enhanced gene replacement in mycobacteria. Microbiology (1999) 1.91
Regulation of the inducible acetamidase gene of Mycobacterium smegmatis. Microbiology (1997) 1.86
An inducible expression system permitting the efficient purification of a recombinant antigen from Mycobacterium smegmatis. FEMS Microbiol Lett (1998) 1.70
Use of a tetracycline-inducible system for conditional expression in Mycobacterium tuberculosis and Mycobacterium smegmatis. Appl Environ Microbiol (2005) 1.45
Improved tetracycline repressors for gene silencing in mycobacteria. Nucleic Acids Res (2009) 1.41
Recombineering mycobacteria and their phages. Nat Rev Microbiol (2008) 1.40
Development and use of a conditional antisense mutagenesis system in mycobacteria. FEMS Microbiol Lett (1997) 1.32
Genetic strategies for antibacterial drug discovery. Nat Rev Genet (2003) 1.30
Synthetic riboswitches that induce gene expression in diverse bacterial species. Appl Environ Microbiol (2010) 1.29
Pristinamycin-inducible gene regulation in mycobacteria. J Biotechnol (2009) 1.28
Transposon-based approaches to identify essential bacterial genes. Trends Microbiol (2000) 1.24
Nitrile-inducible gene expression in mycobacteria. Tuberculosis (Edinb) (2008) 1.18
Development of a repressible mycobacterial promoter system based on two transcriptional repressors. Nucleic Acids Res (2010) 1.13
Tetracycline-inducible gene expression in mycobacteria within an animal host using modified Streptomyces tcp830 regulatory elements. Arch Microbiol (2006) 1.10
Delineating bacteriostatic and bactericidal targets in mycobacteria using IPTG inducible antisense expression. PLoS One (2009) 1.07
Expression of the major porin gene mspA is regulated in Mycobacterium smegmatis. J Bacteriol (2006) 1.00
Expression of Mycobacterium tuberculosis Rv1991c using an arabinose-inducible promoter demonstrates its role as a toxin. FEMS Microbiol Lett (2007) 0.96
Instability of the acetamide-inducible expression vector pJAM2 in Mycobacterium tuberculosis. Plasmid (2005) 0.86
Copper-free click chemistry for dynamic in vivo imaging. Proc Natl Acad Sci U S A (2007) 8.50
Bioorthogonal chemistry: fishing for selectivity in a sea of functionality. Angew Chem Int Ed Engl (2009) 8.15
Chemistry in living systems. Nat Chem Biol (2005) 7.55
A strain-promoted [3 + 2] azide-alkyne cycloaddition for covalent modification of biomolecules in living systems. J Am Chem Soc (2004) 7.51
Glycans in cancer and inflammation--potential for therapeutics and diagnostics. Nat Rev Drug Discov (2005) 6.14
In vivo imaging of membrane-associated glycans in developing zebrafish. Science (2008) 5.45
Incorporation of azides into recombinant proteins for chemoselective modification by the Staudinger ligation. Proc Natl Acad Sci U S A (2001) 4.88
Chemical remodelling of cell surfaces in living animals. Nature (2004) 4.86
A comparative study of bioorthogonal reactions with azides. ACS Chem Biol (2006) 4.26
Cu-free click cycloaddition reactions in chemical biology. Chem Soc Rev (2010) 3.89
Second-generation difluorinated cyclooctynes for copper-free click chemistry. J Am Chem Soc (2008) 3.65
Redirecting lipoic acid ligase for cell surface protein labeling with small-molecule probes. Nat Biotechnol (2007) 3.41
A chemical approach for identifying O-GlcNAc-modified proteins in cells. Proc Natl Acad Sci U S A (2003) 2.97
Copper-free click chemistry in living animals. Proc Natl Acad Sci U S A (2010) 2.76
Rapid Cu-free click chemistry with readily synthesized biarylazacyclooctynones. J Am Chem Soc (2010) 2.74
Introducing genetically encoded aldehydes into proteins. Nat Chem Biol (2007) 2.65
Imaging the glycome. Proc Natl Acad Sci U S A (2008) 2.62
MmpL8 is required for sulfolipid-1 biosynthesis and Mycobacterium tuberculosis virulence. Proc Natl Acad Sci U S A (2003) 2.62
A metabolic labeling approach toward proteomic analysis of mucin-type O-linked glycosylation. Proc Natl Acad Sci U S A (2003) 2.56
From mechanism to mouse: a tale of two bioorthogonal reactions. Acc Chem Res (2011) 2.50
The glycosylphosphatidylinositol anchor: a complex membrane-anchoring structure for proteins. Biochemistry (2008) 2.40
Retracted Reprogramming bacteria to seek and destroy an herbicide. Nat Chem Biol (2010) 2.39
Investigating cellular metabolism of synthetic azidosugars with the Staudinger ligation. J Am Chem Soc (2002) 2.26
Identification, function and structure of the mycobacterial sulfotransferase that initiates sulfolipid-1 biosynthesis. Nat Struct Mol Biol (2004) 2.25
Discovery of aminoacyl-tRNA synthetase activity through cell-surface display of noncanonical amino acids. Proc Natl Acad Sci U S A (2006) 2.23
Mechanistic investigation of the staudinger ligation. J Am Chem Soc (2005) 2.19
Chemical technologies for probing glycans. Cell (2006) 2.04
A cell nanoinjector based on carbon nanotubes. Proc Natl Acad Sci U S A (2007) 2.00
Lipidomics reveals control of Mycobacterium tuberculosis virulence lipids via metabolic coupling. Proc Natl Acad Sci U S A (2007) 1.98
Metabolic labeling of glycans with azido sugars for visualization and glycoproteomics. Methods Enzymol (2006) 1.93
Probing mucin-type O-linked glycosylation in living animals. Proc Natl Acad Sci U S A (2006) 1.85
A hydrophilic azacyclooctyne for Cu-free click chemistry. Org Lett (2008) 1.84
Site-specific chemical modification of recombinant proteins produced in mammalian cells by using the genetically encoded aldehyde tag. Proc Natl Acad Sci U S A (2009) 1.83
Programmed assembly of 3-dimensional microtissues with defined cellular connectivity. Proc Natl Acad Sci U S A (2009) 1.83
Genetic screens and selections for small molecules based on a synthetic riboswitch that activates protein translation. J Am Chem Soc (2004) 1.83
Cholesterol catabolism by Mycobacterium tuberculosis requires transcriptional and metabolic adaptations. Chem Biol (2012) 1.79
A FRET-based fluorogenic phosphine for live-cell imaging with the Staudinger ligation. Angew Chem Int Ed Engl (2008) 1.79
The chemistry and biology of mucin-type O-linked glycosylation. Bioorg Med Chem (2005) 1.78
Deconvoluting the functions of polypeptide N-alpha-acetylgalactosaminyltransferase family members by glycopeptide substrate profiling. Chem Biol (2004) 1.78
Visualizing enveloping layer glycans during zebrafish early embryogenesis. Proc Natl Acad Sci U S A (2010) 1.74
Sulfotransferases and sulfatases in mycobacteria. Chem Biol (2002) 1.74
Integrated microfluidic bioprocessor for single-cell gene expression analysis. Proc Natl Acad Sci U S A (2008) 1.73
Metabolic labeling of glycans with azido sugars and subsequent glycan-profiling and visualization via Staudinger ligation. Nat Protoc (2007) 1.73
Imaging cell surface glycans with bioorthogonal chemical reporters. J Am Chem Soc (2007) 1.65
In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter. Proc Natl Acad Sci U S A (2010) 1.63
Metabolic cross-talk allows labeling of O-linked beta-N-acetylglucosamine-modified proteins via the N-acetylgalactosamine salvage pathway. Proc Natl Acad Sci U S A (2011) 1.61
5'-Adenosinephosphosulphate reductase (CysH) protects Mycobacterium tuberculosis against free radicals during chronic infection phase in mice. Mol Microbiol (2006) 1.59
Site-specific antibody-drug conjugates: the nexus of bioorthogonal chemistry, protein engineering, and drug development. Bioconjug Chem (2015) 1.58
A high-throughput screen for synthetic riboswitches reveals mechanistic insights into their function. Chem Biol (2007) 1.56
Symbol nomenclature for glycan representation. Proteomics (2009) 1.56
Identification of palmitoylated mitochondrial proteins using a bio-orthogonal azido-palmitate analogue. FASEB J (2007) 1.55
Sulfate metabolism in mycobacteria. Chembiochem (2006) 1.55
Metabolic labeling of sialic acids in living animals with alkynyl sugars. Angew Chem Int Ed Engl (2009) 1.53
Copper-free click chemistry for the in situ crosslinking of photodegradable star polymers. Chem Commun (Camb) (2008) 1.52
In vivo imaging of Caenorhabditis elegans glycans. ACS Chem Biol (2009) 1.48
Bringing chemistry to life. Nat Methods (2011) 1.45
Trehalose is required for growth of Mycobacterium smegmatis. J Biol Chem (2004) 1.44
Substrate recognition, protein dynamics, and iron-sulfur cluster in Pseudomonas aeruginosa adenosine 5'-phosphosulfate reductase. J Mol Biol (2006) 1.42
Noncovalent cell surface engineering: incorporation of bioactive synthetic glycopolymers into cellular membranes. J Am Chem Soc (2008) 1.41
Metabolic oligosaccharide engineering as a tool for glycobiology. Curr Opin Chem Biol (2003) 1.41
Site-specific chemical protein conjugation using genetically encoded aldehyde tags. Nat Protoc (2012) 1.40
Programmable cell adhesion encoded by DNA hybridization. Angew Chem Int Ed Engl (2006) 1.39
Selective enrichment of azide-containing peptides from complex mixtures. J Proteome Res (2009) 1.38
Guiding bacteria with small molecules and RNA. J Am Chem Soc (2007) 1.37
A chemical reporter strategy to probe glycoprotein fucosylation. J Am Chem Soc (2006) 1.35
Compositional profiling of heparin/heparan sulfate using mass spectrometry: assay for specificity of a novel extracellular human endosulfatase. Glycobiology (2005) 1.35
Function and structure of a prokaryotic formylglycine-generating enzyme. J Biol Chem (2008) 1.35
A conserved mechanism for sulfonucleotide reduction. PLoS Biol (2005) 1.34
Membrane proteomics of phagosomes suggests a connection to autophagy. Proc Natl Acad Sci U S A (2008) 1.34
Chemical approaches to perturb, profile, and perceive glycans. Acc Chem Res (2009) 1.33
A decade of bioorthogonal chemistry. Acc Chem Res (2011) 1.32
Boron nitride nanotubes are noncytotoxic and can be functionalized for interaction with proteins and cells. J Am Chem Soc (2009) 1.31
Rapid detection, discovery, and identification of post-translationally myristoylated proteins during apoptosis using a bio-orthogonal azidomyristate analog. FASEB J (2007) 1.31
Direct cell surface modification with DNA for the capture of primary cells and the investigation of myotube formation on defined patterns. Langmuir (2009) 1.30
(D)-Amino acid chemical reporters reveal peptidoglycan dynamics of an intracellular pathogen. ACS Chem Biol (2013) 1.29
Difluorobenzocyclooctyne: synthesis, reactivity, and stabilization by beta-cyclodextrin. J Am Chem Soc (2010) 1.29
Synthetic riboswitches that induce gene expression in diverse bacterial species. Appl Environ Microbiol (2010) 1.29
A fluorogenic dye activated by the staudinger ligation. J Am Chem Soc (2003) 1.29
Expanding the diversity of unnatural cell-surface sialic acids. Chembiochem (2004) 1.29
A flow cytometry-based screen for synthetic riboswitches. Nucleic Acids Res (2008) 1.28
Random walks to synthetic riboswitches--a high-throughput selection based on cell motility. Chembiochem (2008) 1.28
5'-adenosinephosphosulfate lies at a metabolic branch point in mycobacteria. J Biol Chem (2002) 1.27
Discovery of sulfated metabolites in mycobacteria with a genetic and mass spectrometric approach. Proc Natl Acad Sci U S A (2002) 1.26
Metabolic labeling of fucosylated glycans in developing zebrafish. ACS Chem Biol (2011) 1.25
Synthesis of heterobifunctional protein fusions using copper-free click chemistry and the aldehyde tag. Angew Chem Int Ed Engl (2012) 1.25
PapA1 and PapA2 are acyltransferases essential for the biosynthesis of the Mycobacterium tuberculosis virulence factor sulfolipid-1. Proc Natl Acad Sci U S A (2007) 1.25
Interfacing carbon nanotubes with living cells. J Am Chem Soc (2006) 1.25
Reactivity of biarylazacyclooctynones in copper-free click chemistry. J Am Chem Soc (2012) 1.24
An inhibitor of the human UDP-GlcNAc 4-epimerase identified from a uridine-based library: a strategy to inhibit O-linked glycosylation. Chem Biol (2002) 1.22
Rapid and selective detection of fatty acylated proteins using omega-alkynyl-fatty acids and click chemistry. J Lipid Res (2009) 1.20
Metabolic functionalization of recombinant glycoproteins. Biochemistry (2004) 1.19
Synthesis, characterization, and theory of [9]-, [12]-, and [18]cycloparaphenylene: carbon nanohoop structures. J Am Chem Soc (2008) 1.19
A new approach to mineralization of biocompatible hydrogel scaffolds: an efficient process toward 3-dimensional bonelike composites. J Am Chem Soc (2003) 1.18
Synthesis and microcontact printing of dual end-functionalized mucin-like glycopolymers for microarray applications. Angew Chem Int Ed Engl (2009) 1.18
A chemical method for labeling lysine methyltransferase substrates. Chembiochem (2010) 1.18
A sulfated metabolite produced by stf3 negatively regulates the virulence of Mycobacterium tuberculosis. Proc Natl Acad Sci U S A (2006) 1.16
Synthetic glycopeptides and glycoproteins as tools for biology. Chem Soc Rev (2004) 1.16
The regulation of sulfur metabolism in Mycobacterium tuberculosis. PLoS Pathog (2011) 1.15
Fluorophore targeting to cellular proteins via enzyme-mediated azide ligation and strain-promoted cycloaddition. J Am Chem Soc (2012) 1.15