PubRank

Kevin G Becker

Author PubWeight™ 221.66‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Resveratrol improves health and survival of mice on a high-calorie diet. Nature 2006 20.91
2 The genetic association database. Nat Genet 2004 11.29
3 Analysis of microarray data using Z score transformation. J Mol Diagn 2003 6.82
4 Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span. Cell Metab 2008 6.22
5 miR-24 Inhibits cell proliferation by targeting E2F2, MYC, and other cell-cycle genes via binding to "seedless" 3'UTR microRNA recognition elements. Mol Cell 2009 5.22
6 LincRNA-p21 suppresses target mRNA translation. Mol Cell 2012 3.87
7 Global analysis of stress-regulated mRNA turnover by using cDNA arrays. Proc Natl Acad Sci U S A 2002 3.71
8 RNA cargoes associating with FMRP reveal deficits in cellular functioning in Fmr1 null mice. Neuron 2003 3.58
9 Transcriptional profiling of aging in human muscle reveals a common aging signature. PLoS Genet 2006 3.34
10 AGEMAP: a gene expression database for aging in mice. PLoS Genet 2007 3.22
11 White spot syndromes of the retina: a hypothesis based on the common genetic hypothesis of autoimmune/inflammatory disease. Am J Ophthalmol 2003 2.97
12 Metformin improves healthspan and lifespan in mice. Nat Commun 2013 2.68
13 MicroRNA expression and identification of putative miRNA targets in ovarian cancer. PLoS One 2008 2.60
14 Application of z-score transformation to Affymetrix data. Appl Bioinformatics 2003 2.56
15 Control of gene expression during T cell activation: alternate regulation of mRNA transcription and mRNA stability. BMC Genomics 2005 2.18
16 Genome-wide analysis of histone methylation reveals chromatin state-based regulation of gene transcription and function of memory CD8+ T cells. Immunity 2009 2.11
17 VEGF-B is dispensable for blood vessel growth but critical for their survival, and VEGF-B targeting inhibits pathological angiogenesis. Proc Natl Acad Sci U S A 2009 1.91
18 Platelets contribute to the pathogenesis of experimental autoimmune encephalomyelitis. Circ Res 2012 1.85
19 SRT1720 improves survival and healthspan of obese mice. Sci Rep 2011 1.81
20 Microarray analysis of gene expression in the prefrontal cortex in schizophrenia: a preliminary study. Schizophr Res 2002 1.76
21 VEGF-B inhibits apoptosis via VEGFR-1-mediated suppression of the expression of BH3-only protein genes in mice and rats. J Clin Invest 2008 1.68
22 Genetic and environmental pathways to complex diseases. BMC Syst Biol 2009 1.67
23 Sex-dependent metabolic, neuroendocrine, and cognitive responses to dietary energy restriction and excess. Endocrinology 2007 1.59
24 Systematic analysis, comparison, and integration of disease based human genetic association data and mouse genetic phenotypic information. BMC Med Genomics 2010 1.57
25 Ubiquitin-mediated proteolysis of HuR by heat shock. EMBO J 2009 1.52
26 Rule-based human gene normalization in biomedical text with confidence estimation. Comput Syst Bioinformatics Conf 2007 1.51
27 Stability regulation of mRNA and the control of gene expression. Ann N Y Acad Sci 2005 1.46
28 Evidence for miR-181 involvement in neuroinflammatory responses of astrocytes. Glia 2013 1.37
29 VENNTURE--a novel Venn diagram investigational tool for multiple pharmacological dataset analysis. PLoS One 2012 1.36
30 Gene expression atlas of the mouse central nervous system: impact and interactions of age, energy intake and gender. Genome Biol 2007 1.35
31 Age-related changes in microRNA levels in serum. Aging (Albany NY) 2013 1.35
32 Survival effect of PDGF-CC rescues neurons from apoptosis in both brain and retina by regulating GSK3beta phosphorylation. J Exp Med 2010 1.33
33 The transcriptional response after oxidative stress is defective in Cockayne syndrome group B cells. Oncogene 2003 1.30
34 Increased APLP1 expression and neurodegeneration in the frontal cortex of manganese-exposed non-human primates. J Neurochem 2008 1.30
35 Gene expression characteristics of CD28null memory phenotype CD8+ T cells and its implication in T-cell aging. Immunol Rev 2005 1.28
36 Hippocampal gene expression patterns underlying the enhancement of memory by running in aged mice. Neurobiol Aging 2008 1.22
37 Global dissociation of HuR-mRNA complexes promotes cell survival after ionizing radiation. EMBO J 2011 1.21
38 Increased fibronectin expression in sturge-weber syndrome fibroblasts and brain tissue. Pediatr Res 2003 1.21
39 Enhanced translation by Nucleolin via G-rich elements in coding and non-coding regions of target mRNAs. Nucleic Acids Res 2011 1.21
40 Sigma-1 receptors regulate hippocampal dendritic spine formation via a free radical-sensitive mechanism involving Rac1xGTP pathway. Proc Natl Acad Sci U S A 2009 1.18
41 Dynamic BRG1 recruitment during T helper differentiation and activation reveals distal regulatory elements. Mol Cell Biol 2011 1.17
42 A genetically engineered ovarian cancer mouse model based on fallopian tube transformation mimics human high-grade serous carcinoma development. J Pathol 2014 1.17
43 iTRAQ analysis of complex proteome alterations in 3xTgAD Alzheimer's mice: understanding the interface between physiology and disease. PLoS One 2008 1.16
44 FACS purification of immunolabeled cell types from adult rat brain. J Neurosci Methods 2011 1.15
45 Nontelomeric TRF2-REST interaction modulates neuronal gene silencing and fate of tumor and stem cells. Curr Biol 2008 1.14
46 Gene expression profiling of oxidative stress on atrial fibrillation in humans. Exp Mol Med 2003 1.14
47 Transcriptome analysis of age-, gender- and diet-associated changes in murine thymus. Cell Immunol 2007 1.14
48 Alterations in immunological and neurological gene expression patterns in Alzheimer's disease tissues. Exp Cell Res 2006 1.13
49 Protein kinase A isozyme switching: eliciting differential cAMP signaling and tumor reversion. Oncogene 2004 1.12
50 Global analysis of HuR-regulated gene expression in colon cancer systems of reducing complexity. Gene Expr 2004 1.12
51 A novel combination of factors, termed SPIE, which promotes dopaminergic neuron differentiation from human embryonic stem cells. PLoS One 2009 1.11
52 CHD5, a brain-specific paralog of Mi2 chromatin remodeling enzymes, regulates expression of neuronal genes. PLoS One 2011 1.11
53 Identification of transformation-related pathways in a breast epithelial cell model using a ribonomics approach. Cancer Res 2008 1.11
54 CREB phosphorylation regulates striatal transcriptional responses in the self-administration model of methamphetamine addiction in the rat. Neurobiol Dis 2013 1.10
55 Identification and analysis of plasticity-induced late-response genes. Proc Natl Acad Sci U S A 2004 1.10
56 Senescence-associated lncRNAs: senescence-associated long noncoding RNAs. Aging Cell 2013 1.09
57 A rapid method for microarray cross platform comparisons using gene expression signatures. Mol Cell Probes 2006 1.09
58 MyD88 expression by CNS-resident cells is pivotal for eliciting protective immunity in brain abscesses. ASN Neuro 2009 1.09
59 Time-dependent c-Myc transactomes mapped by Array-based nuclear run-on reveal transcriptional modules in human B cells. PLoS One 2010 1.08
60 Development of a highly specialized cDNA array for the study and diagnosis of epithelial ovarian cancer. Cancer Res 2002 1.07
61 A mechanism for the inhibition of neural progenitor cell proliferation by cocaine. PLoS Med 2008 1.07
62 Conserved and differential effects of dietary energy intake on the hippocampal transcriptomes of females and males. PLoS One 2008 1.07
63 Microarray analysis reveals interleukin-6 as a novel secretory product of the hypothalamo-neurohypophyseal system. J Biol Chem 2003 1.07
64 Minimal peroxide exposure of neuronal cells induces multifaceted adaptive responses. PLoS One 2010 1.06
65 Methamphetamine causes differential alterations in gene expression and patterns of histone acetylation/hypoacetylation in the rat nucleus accumbens. PLoS One 2012 1.06
66 Interrogation of brain miRNA and mRNA expression profiles reveals a molecular regulatory network that is perturbed by mutant huntingtin. J Neurochem 2012 1.05
67 Amitriptyline-mediated cognitive enhancement in aged 3×Tg Alzheimer's disease mice is associated with neurogenesis and neurotrophic activity. PLoS One 2011 1.04
68 Gene expression and pathway analysis of ovarian cancer cells selected for resistance to cisplatin, paclitaxel, or doxorubicin. J Ovarian Res 2011 1.04
69 Growth factor signals in neural cells: coherent patterns of interaction control multiple levels of molecular and phenotypic responses. J Biol Chem 2008 1.02
70 Transcriptional profiling in an MPNST-derived cell line and normal human Schwann cells. Neuron Glia Biol 2004 1.02
71 Methamphetamine preconditioning alters midbrain transcriptional responses to methamphetamine-induced injury in the rat striatum. PLoS One 2009 1.02
72 Survival of retinal pigment epithelium after exposure to prolonged oxidative injury: a detailed gene expression and cellular analysis. Invest Ophthalmol Vis Sci 2004 1.01
73 Gonadal transcriptome alterations in response to dietary energy intake: sensing the reproductive environment. PLoS One 2009 1.00
74 Effects of aging and calorie restriction on the global gene expression profiles of mouse testis and ovary. BMC Biol 2008 1.00
75 AF5, a CNS cell line immortalized with an N-terminal fragment of SV40 large T: growth, differentiation, genetic stability, and gene expression. Exp Neurol 2002 1.00
76 Kinetic assessment of general gene expression changes during human naive CD4+ T cell activation. Int Immunol 2004 1.00
77 Disease and phenotype gene set analysis of disease-based gene expression in mouse and human. Physiol Genomics 2010 1.00
78 Dissecting the circuitry of protein kinase A and cAMP signaling in cancer genesis: antisense, microarray, gene overexpression, and transcription factor decoy. Ann N Y Acad Sci 2002 0.99
79 Neonatal dopamine depletion induces changes in morphogenesis and gene expression in the developing cortex. Neurotox Res 2007 0.98
80 Transcriptional changes common to human cocaine, cannabis and phencyclidine abuse. PLoS One 2006 0.98
81 Single round of antigen receptor signaling programs naive B cells to receive T cell help. Immunity 2010 0.97
82 Differential gene expression patterns in cyclooxygenase-1 and cyclooxygenase-2 deficient mouse brain. Genome Biol 2007 0.96
83 Molecular changes in brain aging and Alzheimer's disease are mirrored in experimentally silenced cortical neuron networks. Neurobiol Aging 2010 0.96
84 Paradoxical microRNAs: individual gene repressors, global translation enhancers. Cell Cycle 2011 0.96
85 Gene expression responses to DNA damage are altered in human aging and in Werner Syndrome. Oncogene 2005 0.95
86 Growth inhibition by miR-519 via multiple p21-inducing pathways. Mol Cell Biol 2012 0.95
87 Role of heparin binding growth factors in nigrostriatal dopamine system development and Parkinson's disease. Brain Res 2007 0.95
88 SRT2104 extends survival of male mice on a standard diet and preserves bone and muscle mass. Aging Cell 2014 0.94
89 Polymorphisms in the novel gene acyloxyacyl hydroxylase (AOAH) are associated with asthma and associated phenotypes. J Allergy Clin Immunol 2006 0.94
90 Activation of Wnt5A signaling is required for CXC chemokine ligand 12-mediated T-cell migration. Blood 2009 0.93
91 Adipocyte gene expression is altered in formerly obese mice and as a function of diet composition. J Nutr 2008 0.93
92 CYFIP2 is highly abundant in CD4+ cells from multiple sclerosis patients and is involved in T cell adhesion. Eur J Immunol 2004 0.91
93 Claudin-7 is frequently overexpressed in ovarian cancer and promotes invasion. PLoS One 2011 0.91
94 Euglycemic agent-mediated hypothalamic transcriptomic manipulation in the N171-82Q model of Huntington disease is related to their physiological efficacy. J Biol Chem 2012 0.91
95 Gene expression in the conversion of early-phase to late-phase long-term potentiation. Ann N Y Acad Sci 2005 0.91
96 Microarray screening of suppression subtractive hybridization-PCR cDNA libraries identifies novel RNAs regulated by dehydration in the rat supraoptic nucleus. Physiol Genomics 2005 0.91
97 Molecular analysis of bovine spongiform encephalopathy infection by cDNA arrays. J Gen Virol 2007 0.91
98 Environmental enrichment during adolescence regulates gene expression in the striatum of mice. Brain Res 2008 0.91
99 Microarray analysis of oxidative stress regulated genes in mesencephalic dopaminergic neuronal cells: relevance to oxidative damage in Parkinson's disease. Neurochem Int 2007 0.90
100 Multiple oxygen tension environments reveal diverse patterns of transcriptional regulation in primary astrocytes. PLoS One 2011 0.90
101 Changes in mouse cognition and hippocampal gene expression observed in a mild physical- and blast-traumatic brain injury. Neurobiol Dis 2013 0.90
102 ATM regulates a DNA damage response posttranscriptional RNA operon in lymphocytes. Blood 2011 0.90
103 Exendin-4, a glucagon-like peptide-1 receptor agonist prevents mTBI-induced changes in hippocampus gene expression and memory deficits in mice. Exp Neurol 2012 0.90
104 Similarities in features of autism and asthma and a possible link to acetaminophen use. Med Hypotheses 2009 0.89
105 Significant modulation of mitochondrial electron transport system by nicotine in various rat brain regions. Mitochondrion 2009 0.89
106 Protease activated receptor signaling is required for African trypanosome traversal of human brain microvascular endothelial cells. PLoS Negl Trop Dis 2009 0.89
107 Wnt5A promotes an adaptive, senescent-like stress response, while continuing to drive invasion in melanoma cells. Pigment Cell Melanoma Res 2014 0.89
108 DSCR1(Adapt78) modulates expression of SOD1. FASEB J 2004 0.88
109 Combined treatment of rapamycin and dietary restriction has a larger effect on the transcriptome and metabolome of liver. Aging Cell 2013 0.88
110 Transcriptome analysis of murine thymocytes reveals age-associated changes in thymic gene expression. Int J Med Sci 2009 0.87
111 Krüppel-like factor 4 (KLF4) directly regulates proliferation in thymocyte development and IL-17 expression during Th17 differentiation. FASEB J 2011 0.87
112 Regulatory subunits of PKA define an axis of cellular proliferation/differentiation in ovarian cancer cells. BMC Med Genomics 2008 0.87
113 Extension of lifespan in C. elegans by naphthoquinones that act through stress hormesis mechanisms. PLoS One 2011 0.86
114 Methamphetamine preconditioning causes differential changes in striatal transcriptional responses to large doses of the drug. Dose Response 2010 0.86
115 Age-associated alterations in inducible gene transcription in human CD4+ T lymphocytes. Aging (Albany NY) 2013 0.86
116 Changes in gene expression linked to methamphetamine-induced dopaminergic neurotoxicity. J Neurosci 2002 0.85
117 Differentially expressed genes in MHC-compatible rat strains that are susceptible or resistant to experimental autoimmune uveitis. Invest Ophthalmol Vis Sci 2008 0.84
118 Gene expression profiling reveals distinct cocaine-responsive genes in human fetal CNS cell types. J Addict Med 2009 0.84
119 Increases in expression of 14-3-3 eta and 14-3-3 zeta transcripts during neuroprotection induced by delta9-tetrahydrocannabinol in AF5 cells. J Neurosci Res 2007 0.84
120 Methamphetamine-induced dopamine-independent alterations in striatal gene expression in the 6-hydroxydopamine hemiparkinsonian rats. PLoS One 2010 0.83
121 Cortical gene transcription response patterns to water maze training in aged mice. BMC Neurosci 2011 0.83
122 Antigen-specific gene expression profiles of peripheral blood mononuclear cells do not reflect those of T-lymphocyte subsets. Clin Diagn Lab Immunol 2004 0.83
123 Sporadic Alzheimer disease fibroblasts display an oxidative stress phenotype. Free Radic Biol Med 2012 0.83
124 IL-10 transcription is negatively regulated by BAF180, a component of the SWI/SNF chromatin remodeling enzyme. BMC Immunol 2012 0.82
125 Altered gene expression in pulmonary tissue of tryptophan hydroxylase-1 knockout mice: implications for pulmonary arterial hypertension. PLoS One 2011 0.82
126 Possible angiogenic roles for claudin-4 in ovarian cancer. Cancer Biol Ther 2009 0.82
127 Increased prevalence of autoimmunity in patients with white spot syndromes and their family members. Arch Ophthalmol 2009 0.82
128 Identification and characterization of unique tumoricidal genes in rat umbilical cord matrix stem cells. Mol Pharm 2011 0.82
129 Genome-wide profiling identifies a subset of methamphetamine (METH)-induced genes associated with METH-induced increased H4K5Ac binding in the rat striatum. BMC Genomics 2013 0.82
130 Identification and characterization of metallothionein-1 and -2 gene expression in the context of (+/-)3,4-methylenedioxymethamphetamine-induced toxicity to brain dopaminergic neurons. J Neurosci 2004 0.81
131 Microarray analysis in Tourette syndrome postmortem putamen. J Neurol Sci 2004 0.81
132 Molecular signature and in vivo behavior of bone marrow endosteal and subendosteal stromal cell populations and their relevance to hematopoiesis. Exp Cell Res 2012 0.81
133 Non-steroidal anti-inflammatory drugs decrease E2F1 expression and inhibit cell growth in ovarian cancer cells. PLoS One 2013 0.81
134 AMPK agonist AICAR improves cognition and motor coordination in young and aged mice. Learn Mem 2014 0.81
135 Microarray technology and its application on nicotine research. Mol Neurobiol 2002 0.81
136 Effect of genistein on the expression of bone metabolism genes in ovariectomized mice using a cDNA microarray. J Nutr Biochem 2005 0.80
137 A genome-wide view of antisense. Nat Biotechnol 2003 0.80
138 Molecular characterization of the transition to mid-life in Caenorhabditis elegans. Age (Dordr) 2012 0.80
139 Methamphetamine-induced gene expression profiles in the striatum of male rat pups exposed to the drug in utero. Brain Res Dev Brain Res 2003 0.79
140 Microarray and pathway analysis reveals decreased CDC25A and increased CDC42 associated with slow growth of BCL2 overexpressing immortalized breast cell line. Cell Cycle 2008 0.79
141 Profile of changes in gene expression in cultured hippocampal neurones evoked by the GABAB receptor agonist baclofen. Physiol Genomics 2005 0.79
142 Distinct inhibitory effects on mTOR signaling by ethanol and INK128 in diffuse large B-cell lymphoma. Cell Commun Signal 2015 0.79
143 National Institute on Aging microarray facility--resources for gerontology research. J Gerontol A Biol Sci Med Sci 2005 0.79
144 A genomic-scale view of the cAMP response element-enhancer decoy: a tumor target-based genetic tool. Proc Natl Acad Sci U S A 2002 0.78
145 Long-term artificial sweetener acesulfame potassium treatment alters neurometabolic functions in C57BL/6J mice. PLoS One 2013 0.78
146 Double round hybridization of membrane based cDNA arrays: improved background reduction and data replication. J Neurosci Methods 2002 0.78
147 Toll-like receptor 2 (TLR2)-TLR9 crosstalk dictates IL-12 family cytokine production in microglia. Glia 2011 0.78
148 Impact of pyrrolidine dithiocarbamate and interleukin-6 on mammalian target of rapamycin complex 1 regulation and global protein translation. J Pharmacol Exp Ther 2011 0.77
149 Autism, immune dysfunction and Vitamin D. Acta Psychiatr Scand 2011 0.77
150 Metabolic context regulates distinct hypothalamic transcriptional responses to antiaging interventions. Int J Endocrinol 2012 0.77
151 Naïve rat umbilical cord matrix stem cells significantly attenuate mammary tumor growth through modulation of endogenous immune responses. Cytotherapy 2013 0.77
152 Dietary restriction mitigates cocaine-induced alterations of olfactory bulb cellular plasticity and gene expression, and behavior. J Neurochem 2010 0.77
153 Genome-wide modeling of complex phenotypes in Caenorhabditis elegans and Drosophila melanogaster. BMC Genomics 2013 0.75
154 Corrigendum: sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance. Nature 2016 0.75
155 Autism and urbanization. Am J Public Health 2010 0.75
156 Age-related brain expression and regulation of the chemokine CCL4/MIP-1β in APP/PS1 double-transgenic mice. J Neuropathol Exp Neurol 2014 0.75