Published in J Physiol on March 12, 2012
Pannexin 1 channels mediate the release of ATP into the lumen of the rat urinary bladder. J Physiol (2015) 1.59
Rat, mouse, and primate models of chronic glaucoma show sustained elevation of extracellular ATP and altered purinergic signaling in the posterior eye. Invest Ophthalmol Vis Sci (2015) 1.46
Critical pathogenic events underlying progression of neurodegeneration in glaucoma. Prog Retin Eye Res (2012) 1.40
From mechanosensitivity to inflammatory responses: new players in the pathology of glaucoma. Curr Eye Res (2013) 1.31
Posttranslational modifications in connexins and pannexins. J Membr Biol (2012) 1.00
Porphyromonas gingivalis-nucleoside-diphosphate-kinase inhibits ATP-induced reactive-oxygen-species via P2X7 receptor/NADPH-oxidase signalling and contributes to persistence. Cell Microbiol (2013) 1.00
The bizarre pharmacology of the ATP release channel pannexin1. Neuropharmacology (2013) 0.93
Lysosomal alkalinization, lipid oxidation, and reduced phagosome clearance triggered by activation of the P2X7 receptor. FASEB J (2013) 0.93
ATP release through pannexon channels. Philos Trans R Soc Lond B Biol Sci (2015) 0.92
Mechanical stimulation evokes rapid increases in extracellular adenosine concentration in the prefrontal cortex. J Neurochem (2014) 0.92
Vesicular expression and release of ATP from dopaminergic neurons of the mouse retina and midbrain. Front Cell Neurosci (2015) 0.91
Role of P2X7 receptors in the development of diabetic retinopathy. World J Diabetes (2014) 0.86
Amplification of human platelet activation by surface pannexin-1 channels. J Thromb Haemost (2014) 0.83
Hypoxia-induced changes in Ca(2+) mobilization and protein phosphorylation implicated in impaired wound healing. Am J Physiol Cell Physiol (2014) 0.83
Astrocytes in the optic nerve head express putative mechanosensitive channels. Mol Vis (2015) 0.83
Inflammation, pain, and pressure--purinergic signaling in oral tissues. J Dent Res (2012) 0.82
Emerging functions of pannexin 1 in the eye. Front Cell Neurosci (2014) 0.81
Retinal glial responses to optic nerve crush are attenuated in Bax-deficient mice and modulated by purinergic signaling pathways. J Neuroinflammation (2016) 0.80
Purinergic regulation of inflammasome activation after central nervous system injury. J Gen Physiol (2012) 0.80
L-Lactate protects neurons against excitotoxicity: implication of an ATP-mediated signaling cascade. Sci Rep (2016) 0.80
P2X7R large pore is partially blocked by pore forming proteins antagonists in astrocytes. J Bioenerg Biomembr (2016) 0.78
Possible role of hemichannels in cancer. Front Physiol (2014) 0.78
Adenosine A2AR blockade prevents neuroinflammation-induced death of retinal ganglion cells caused by elevated pressure. J Neuroinflammation (2015) 0.78
Functional and molecular characterization of ex vivo cultured epiretinal membrane cells from human proliferative diabetic retinopathy. Biomed Res Int (2013) 0.78
P2 receptors in renal autoregulation. Curr Vasc Pharmacol (2014) 0.78
Emerging concepts regarding pannexin 1 in the vasculature. Biochem Soc Trans (2015) 0.78
P2X7 receptors in neurohypophysial terminals: evidence for their role in arginine-vasopressin secretion. J Cell Physiol (2014) 0.76
Neuronal Release of Cytokine IL-3 Triggered by Mechanosensitive Autostimulation of the P2X7 Receptor Is Neuroprotective. Front Cell Neurosci (2016) 0.76
Characterization of ex vivo cultured neuronal- and glial- like cells from human idiopathic epiretinal membranes. BMC Ophthalmol (2014) 0.76
Pannexin1 Channels Are Required for Chemokine-Mediated Migration of CD4+ T Lymphocytes: Role in Inflammation and Experimental Autoimmune Encephalomyelitis. J Immunol (2016) 0.75
Blockade of P2X7 receptors or pannexin-1 channels similarly attenuates postischemic damage. J Cereb Blood Flow Metab (2015) 0.75
Characterization of the Circumlimbal Suture Model of Chronic IOP Elevation in Mice and Assessment of Changes in Gene Expression of Stretch Sensitive Channels. Front Neurosci (2017) 0.75
Increased membrane localization of pannexin1 in human corneal synaptosomes causes enhanced stimulated ATP release in chronic diabetes mellitus. Medicine (Baltimore) (2016) 0.75
Purinergic Signaling in Gut Inflammation: The Role of Connexins and Pannexins. Front Neurosci (2016) 0.75
Role of P2X7 receptors in neuronal death in the retina. Neural Regen Res (2014) 0.75
ATP release during cell swelling activates a Ca(2+)-dependent Cl(-) current by autocrine mechanism in mouse hippocampal microglia. Sci Rep (2017) 0.75
P2X7R modulation of visually evoked synaptic responses in the retina. Purinergic Signal (2016) 0.75
The P2X7 receptor links mechanical strain to cytokine IL-6 up-regulation and release in neurons and astrocytes. J Neurochem (2017) 0.75
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Propagation of intercellular calcium waves in retinal astrocytes and Müller cells. J Neurosci (2001) 2.72
Glial cell inhibition of neurons by release of ATP. J Neurosci (2003) 2.32
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Nonsynaptic communication through ATP release from volume-activated anion channels in axons. Sci Signal (2010) 1.71
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Structure-activity relationship studies on a series of novel, substituted 1-benzyl-5-phenyltetrazole P2X7 antagonists. J Med Chem (2006) 1.36
Fluid flow induces mechanosensitive ATP release, calcium signalling and Cl- transport in biliary epithelial cells through a PKCzeta-dependent pathway. J Physiol (2008) 1.36
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Metabolic autocrine regulation of neurons involves cooperation among pannexin hemichannels, adenosine receptors, and KATP channels. J Neurosci (2010) 1.31
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Acute retinal ganglion cell injury caused by intraocular pressure spikes is mediated by endogenous extracellular ATP. Eur J Neurosci (2007) 1.16
Mechanosensitivity of mouse tracheal ciliary beat frequency: roles for Ca2+, purinergic signaling, tonicity, and viscosity. Am J Physiol Lung Cell Mol Physiol (2006) 1.15
Release of ATP from rat urinary bladder mucosa: role of acid, vanilloids and stretch. Br J Pharmacol (2009) 1.12
Stimulation of the P2X7 receptor kills rat retinal ganglion cells in vivo. Exp Eye Res (2010) 1.12
Acute increase of intraocular pressure releases ATP into the anterior chamber. Exp Eye Res (2007) 1.12
Methylene ATP analogs as modulators of extracellular ATP metabolism and accumulation. Br J Pharmacol (2004) 1.11
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Identification of the A3 adenosine receptor in rat retinal ganglion cells. Mol Vis (2006) 1.04
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Balance of purines may determine life or death of retinal ganglion cells as A3 adenosine receptors prevent loss following P2X7 receptor stimulation. J Neurochem (2006) 1.03
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Human trabecular meshwork cell volume regulation. Am J Physiol Cell Physiol (2002) 0.99
Raised intracranial pressure in acute viral encephalitis. Clin Neurol Neurosurg (2009) 0.96
Traumatic injury activates protein kinase B/Akt in cultured astrocytes: role of extracellular ATP and P2 purinergic receptors. J Neurotrauma (2005) 0.94
Opposite effects of zinc on human and rat P2X2 receptors. J Neurosci (2008) 0.92
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Sustained elevation of extracellular ATP in aqueous humor from humans with primary chronic angle-closure glaucoma. Exp Eye Res (2011) 0.89
The P2X(7) receptor in retinal ganglion cells: A neuronal model of pressure-induced damage and protection by a shifting purinergic balance. Purinergic Signal (2009) 0.82
Imaging localized astrocyte ATP release with firefly luciferase beads attached to the cell surface. Anal Chem (2008) 0.79
Ionic dependence of the velocity of release of ATP from permeabilized cholinergic synaptic vesicles. Neuroscience (2007) 0.77
Direct labeling and visualization of blood vessels with lipophilic carbocyanine dye DiI. Nat Protoc (2008) 2.29
Encapsulated cell-based delivery of CNTF reduces photoreceptor degeneration in animal models of retinitis pigmentosa. Invest Ophthalmol Vis Sci (2002) 1.97
Pannexin 1 channels mediate the release of ATP into the lumen of the rat urinary bladder. J Physiol (2015) 1.59
Stimulation of P2X7 receptors elevates Ca2+ and kills retinal ganglion cells. Invest Ophthalmol Vis Sci (2005) 1.40
CNTF induces regeneration of cone outer segments in a rat model of retinal degeneration. PLoS One (2010) 1.39
From mechanosensitivity to inflammatory responses: new players in the pathology of glaucoma. Curr Eye Res (2013) 1.31
A 4-year update on the safety of sildenafil citrate (Viagra). Urology (2002) 1.28
Non-neuronal acetylcholine and urinary bladder urothelium. Life Sci (2007) 1.27
Expression and function of bradykinin B1 and B2 receptors in normal and inflamed rat urinary bladder urothelium. J Physiol (2004) 1.26
Restoration of lysosomal pH in RPE cells from cultured human and ABCA4(-/-) mice: pharmacologic approaches and functional recovery. Invest Ophthalmol Vis Sci (2008) 1.24
CATSPER channel-mediated Ca2+ entry into mouse sperm triggers a tail-to-head propagation. Biol Reprod (2007) 1.24
Regulation of rod phototransduction machinery by ciliary neurotrophic factor. J Neurosci (2006) 1.23
Release of ATP from retinal pigment epithelial cells involves both CFTR and vesicular transport. Am J Physiol Cell Physiol (2004) 1.19
Stimulation of the P2X7 receptor kills rat retinal ganglion cells in vivo. Exp Eye Res (2010) 1.12
Acute increase of intraocular pressure releases ATP into the anterior chamber. Exp Eye Res (2007) 1.12
Mechanisms of ATP release by human trabecular meshwork cells, the enabling step in purinergic regulation of aqueous humor outflow. J Cell Physiol (2012) 1.06
Paracrine stimulation of surfactant secretion by extracellular ATP in response to mechanical deformation. Am J Physiol Lung Cell Mol Physiol (2005) 1.05
Acidic nanoparticles are trafficked to lysosomes and restore an acidic lysosomal pH and degradative function to compromised ARPE-19 cells. PLoS One (2012) 1.05
Identification of the A3 adenosine receptor in rat retinal ganglion cells. Mol Vis (2006) 1.04
Balance of purines may determine life or death of retinal ganglion cells as A3 adenosine receptors prevent loss following P2X7 receptor stimulation. J Neurochem (2006) 1.03
Pathways for ATP release by bovine ciliary epithelial cells, the initial step in purinergic regulation of aqueous humor inflow. Am J Physiol Cell Physiol (2010) 1.02
Expression and function of rat urothelial P2Y receptors. Am J Physiol Renal Physiol (2008) 1.01
Choroidal thickness in fellow eyes of patients with acute primary angle-closure measured by enhanced depth imaging spectral-domain optical coherence tomography. Invest Ophthalmol Vis Sci (2013) 1.01
Degradation of extracellular ATP by the retinal pigment epithelium. Am J Physiol Cell Physiol (2005) 0.98
Collagen: a potential factor involved in the pathogenesis of glaucoma. Med Sci Monit Basic Res (2013) 0.97
Compression and tension: differential effects on matrix accumulation by periodontal ligament fibroblasts in vitro. Connect Tissue Res (2004) 0.97
Translocation of the retinal pigment epithelium and formation of sub-retinal pigment epithelium deposit induced by subretinal deposit. Mol Vis (2007) 0.96
Stimulation of the D5 dopamine receptor acidifies the lysosomal pH of retinal pigmented epithelial cells and decreases accumulation of autofluorescent photoreceptor debris. J Neurochem (2012) 0.96
Differential P1-purinergic modulation of human Schlemm's canal inner-wall cells. Am J Physiol Cell Physiol (2004) 0.95
Cystic fibrosis transmembrane conductance regulator contributes to reacidification of alkalinized lysosomes in RPE cells. Am J Physiol Cell Physiol (2012) 0.94
Glutamate acts at NMDA receptors on fresh bovine and on cultured human retinal pigment epithelial cells to trigger release of ATP. J Physiol (2006) 0.94
Lysosomal alkalinization, lipid oxidation, and reduced phagosome clearance triggered by activation of the P2X7 receptor. FASEB J (2013) 0.93
The A3 adenosine receptor attenuates the calcium rise triggered by NMDA receptors in retinal ganglion cells. Neurochem Int (2009) 0.91
Sustained elevation of extracellular ATP in aqueous humor from humans with primary chronic angle-closure glaucoma. Exp Eye Res (2011) 0.89
Photoreceptor protection by cardiotrophin-1 in transgenic rats with the rhodopsin mutation s334ter. Invest Ophthalmol Vis Sci (2003) 0.89
cAMP-activated maxi-Cl(-) channels in native bovine pigmented ciliary epithelial cells. Am J Physiol Cell Physiol (2004) 0.88
Stimulation of the P2Y1 receptor up-regulates nucleoside-triphosphate diphosphohydrolase-1 in human retinal pigment epithelial cells. J Pharmacol Exp Ther (2007) 0.87
TRPC6 channel protects retinal ganglion cells in a rat model of retinal ischemia/reperfusion-induced cell death. Invest Ophthalmol Vis Sci (2010) 0.87
CNTF negatively regulates the phototransduction machinery in rod photoreceptors: implication for light-induced photostasis plasticity. Adv Exp Med Biol (2008) 0.86
Rescue of compromised lysosomes enhances degradation of photoreceptor outer segments and reduces lipofuscin-like autofluorescence in retinal pigmented epithelial cells. Adv Exp Med Biol (2014) 0.85
Acute nonarteritic anterior ischemic optic neuropathy and exposure to phosphodiesterase type 5 inhibitors. J Sex Med (2014) 0.85
Stimulation of an alpha1-adrenergic receptor downregulates ecto-5' nucleotidase activity on the apical membrane of RPE cells. Purinergic Signal (2006) 0.84
Noninvasive assessment of aqueous humor turnover in the mouse eye. Invest Ophthalmol Vis Sci (2003) 0.83
Regeneration of cone outer segments induced by CNTF. Adv Exp Med Biol (2012) 0.83
Matrix synthesis by bladder smooth muscle cells is modulated by stretch frequency. In Vitro Cell Dev Biol Anim (2003) 0.82
The P2X(7) receptor in retinal ganglion cells: A neuronal model of pressure-induced damage and protection by a shifting purinergic balance. Purinergic Signal (2009) 0.82
Inhibition of swelling-activated Cl- currents by functional anti-ClC-3 antibody in native bovine non-pigmented ciliary epithelial cells. Invest Ophthalmol Vis Sci (2005) 0.82
Partial bladder outlet obstruction alters Ca2+ sensitivity of force, but not of MLC phosphorylation, in bladder smooth muscle. Am J Physiol Renal Physiol (2003) 0.82
Altered extracellular matrix expression in the diverted fetal sheep bladder. J Urol (2007) 0.81
Superior calcium homeostasis of extraocular muscles. Exp Eye Res (2010) 0.81
A double-blind placebo-controlled evaluation of the acute effects of sildenafil citrate (Viagra) on visual function in subjects with early-stage age-related macular degeneration. Am J Ophthalmol (2002) 0.81
Sequential platelet-derived growth factor-simvastatin release promotes dentoalveolar regeneration. Tissue Eng Part A (2013) 0.80
Response of the fetal sheep bladder to urinary diversion. J Urol (2003) 0.80
Nerve fiber layer splaying at vascular crossings. Invest Ophthalmol Vis Sci (2002) 0.80
Urinary diversion results in marked decreases in proliferation and apoptosis in fetal bladder. J Urol (2012) 0.80
Caspase inhibitors protect against NMDA-mediated retinal ganglion cell death. Clin Experiment Ophthalmol (2011) 0.80
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The P2X(7) receptor in retinal ganglion cells: A neuronal model of pressure-induced damage and protection by a shifting purinergic balance. Purinergic Signal (2008) 0.77
Beta and gamma-sarcoglycans are decreased in the detrusor smooth muscle cells of the partially obstructed rabbit bladder. J Urol (2008) 0.76
Increased expression of the transient receptor potential cation channel 6 gene in patients with primary open-angle glaucoma. Clin Experiment Ophthalmol (2013) 0.76
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Recombinant insulin-like growth factor-1 activates satellite cells in the mouse urethral rhabdosphincter. BMC Urol (2013) 0.75