Published in J Biol Chem on August 30, 2010
Membrane fission reactions of the mammalian ESCRT pathway. Annu Rev Biochem (2013) 1.91
The ESCRT machinery: from the plasma membrane to endosomes and back again. Crit Rev Biochem Mol Biol (2014) 1.12
Requirements for the catalytic cycle of the N-ethylmaleimide-Sensitive Factor (NSF). Biochim Biophys Acta (2011) 1.08
Structure and function of the membrane deformation AAA ATPase Vps4. Biochim Biophys Acta (2011) 1.07
Coordinated binding of Vps4 to ESCRT-III drives membrane neck constriction during MVB vesicle formation. J Cell Biol (2014) 1.05
Regulation of Vps4 during MVB sorting and cytokinesis. Traffic (2011) 1.04
Quantitative proteomic analysis of Niemann-Pick disease, type C1 cerebellum identifies protein biomarkers and provides pathological insight. PLoS One (2012) 1.00
Interactions of the human LIP5 regulatory protein with endosomal sorting complexes required for transport. J Biol Chem (2012) 0.99
The oligomeric state of the active Vps4 AAA ATPase. J Mol Biol (2013) 0.95
Reverse-topology membrane scission by the ESCRT proteins. Nat Rev Mol Cell Biol (2016) 0.90
Assembly and disassembly of the ESCRT-III membrane scission complex. FEBS Lett (2011) 0.89
Vesicle formation within endosomes: An ESCRT marks the spot. Commun Integr Biol (2012) 0.88
Relief of autoinhibition enhances Vta1 activation of Vps4 via the Vps4 stimulatory element. J Biol Chem (2013) 0.88
A novel mechanism of regulating the ATPase VPS4 by its cofactor LIP5 and the endosomal sorting complex required for transport (ESCRT)-III protein CHMP5. J Biol Chem (2015) 0.87
ALIX and ESCRT-I/II function as parallel ESCRT-III recruiters in cytokinetic abscission. J Cell Biol (2016) 0.86
Interactome of the plant-specific ESCRT-III component AtVPS2.2 in Arabidopsis thaliana. J Proteome Res (2011) 0.84
Binding of Substrates to the Central Pore of the Vps4 ATPase Is Autoinhibited by the Microtubule Interacting and Trafficking (MIT) Domain and Activated by MIT Interacting Motifs (MIMs). J Biol Chem (2015) 0.83
Vps4 stimulatory element of the cofactor Vta1 contacts the ATPase Vps4 α7 and α9 to stimulate ATP hydrolysis. J Biol Chem (2014) 0.82
Meiotic Clade AAA ATPases: Protein Polymer Disassembly Machines. J Mol Biol (2015) 0.82
The linker region plays a regulatory role in assembly and activity of the Vps4 AAA ATPase. J Biol Chem (2013) 0.82
Vfa1 binds to the N-terminal microtubule-interacting and trafficking (MIT) domain of Vps4 and stimulates its ATPase activity. J Biol Chem (2014) 0.81
Stable isotope labeling with amino acids in cell culture based mass spectrometry approach to detect transient protein interactions using substrate trapping. Anal Chem (2011) 0.81
A novel endosomal sorting complex required for transport (ESCRT) component in Arabidopsis thaliana controls cell expansion and development. J Biol Chem (2014) 0.80
Asymmetric ring structure of Vps4 required for ESCRT-III disassembly. Nat Commun (2015) 0.80
Doa4 function in ILV budding is restricted through its interaction with the Vps20 subunit of ESCRT-III. J Cell Sci (2013) 0.80
Structural basis of protein translocation by the Vps4-Vta1 AAA ATPase. Elife (2017) 0.79
Synergistic activation of p21-activated kinase 1 by phosphatidylinositol 4,5-bisphosphate and Rho GTPases. J Biol Chem (2013) 0.77
The role of the N-D1 linker of the N-ethylmaleimide-sensitive factor in the SNARE disassembly. PLoS One (2013) 0.77
ALIX Regulates the Ubiquitin-Independent Lysosomal Sorting of the P2Y1 Purinergic Receptor via a YPX3L Motif. PLoS One (2016) 0.76
Conformational Changes in the Endosomal Sorting Complex Required for the Transport III Subunit Ist1 Lead to Distinct Modes of ATPase Vps4 Regulation. J Biol Chem (2015) 0.76
Structure of the alpha beta tubulin dimer by electron crystallography. Nature (1998) 11.07
An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor. Cell (2006) 10.28
AAA+ proteins: have engine, will work. Nat Rev Mol Cell Biol (2005) 7.73
The Vps4p AAA ATPase regulates membrane association of a Vps protein complex required for normal endosome function. EMBO J (1998) 7.68
Escrt-III: an endosome-associated heterooligomeric protein complex required for mvb sorting. Dev Cell (2002) 7.32
AAA+ superfamily ATPases: common structure--diverse function. Genes Cells (2001) 5.83
Lysosomes: fusion and function. Nat Rev Mol Cell Biol (2007) 5.74
Colorimetric determination of phospholipids with ammonium ferrothiocyanate. Anal Biochem (1980) 5.45
Endosomal transport function in yeast requires a novel AAA-type ATPase, Vps4p. EMBO J (1997) 5.05
Plasma membrane deformation by circular arrays of ESCRT-III protein filaments. J Cell Biol (2008) 4.66
Membrane scission by the ESCRT-III complex. Nature (2009) 4.66
Central pore residues mediate the p97/VCP activity required for ERAD. Mol Cell (2006) 4.56
The ATPase activity of SecA is regulated by acidic phospholipids, SecY, and the leader and mature domains of precursor proteins. Cell (1990) 4.00
ESCRT-III recognition by VPS4 ATPases. Nature (2007) 3.64
Dynamics of substrate denaturation and translocation by the ClpXP degradation machine. Mol Cell (2000) 3.52
Functional reconstitution of ESCRT-III assembly and disassembly. Cell (2009) 3.52
ESCRTing proteins in the endocytic pathway. Trends Biochem Sci (2007) 3.48
Structural basis for selective recognition of ESCRT-III by the AAA ATPase Vps4. Nature (2007) 3.47
Pore loops of the AAA+ ClpX machine grip substrates to drive translocation and unfolding. Nat Struct Mol Biol (2008) 3.41
Helical structures of ESCRT-III are disassembled by VPS4. Science (2008) 3.38
Structural basis for budding by the ESCRT-III factor CHMP3. Dev Cell (2006) 3.18
Structure/function analysis of four core ESCRT-III proteins reveals common regulatory role for extreme C-terminal domain. Traffic (2007) 2.76
Ordered assembly of the ESCRT-III complex on endosomes is required to sequester cargo during MVB formation. Dev Cell (2008) 2.74
Loops in the central channel of ClpA chaperone mediate protein binding, unfolding, and translocation. Cell (2005) 2.69
Release of autoinhibition converts ESCRT-III components into potent inhibitors of HIV-1 budding. Proc Natl Acad Sci U S A (2006) 2.63
Structural and mechanistic studies of VPS4 proteins. EMBO J (2005) 2.58
Interaction of the mammalian endosomal sorting complex required for transport (ESCRT) III protein hSnf7-1 with itself, membranes, and the AAA+ ATPase SKD1. J Biol Chem (2005) 2.50
Did2 coordinates Vps4-mediated dissociation of ESCRT-III from endosomes. J Cell Biol (2006) 2.24
Two distinct modes of ESCRT-III recognition are required for VPS4 functions in lysosomal protein targeting and HIV-1 budding. Dev Cell (2008) 2.23
Recycling of ESCRTs by the AAA-ATPase Vps4 is regulated by a conserved VSL region in Vta1. J Cell Biol (2006) 2.18
Structural basis of microtubule severing by the hereditary spastic paraplegia protein spastin. Nature (2008) 2.15
Conserved arginine residues implicated in ATP hydrolysis, nucleotide-sensing, and inter-subunit interactions in AAA and AAA+ ATPases. J Struct Biol (2004) 2.15
Microtubule disassembly by ATP-dependent oligomerization of the AAA enzyme katanin. Science (1999) 2.15
Structure and ESCRT-III protein interactions of the MIT domain of human VPS4A. Proc Natl Acad Sci U S A (2005) 2.12
An intersubunit signaling network coordinates ATP hydrolysis by m-AAA proteases. Mol Cell (2009) 2.12
Distinct roles for the AAA ATPases NSF and p97 in the secretory pathway. Mol Biol Cell (2003) 2.09
Structural basis for ESCRT-III protein autoinhibition. Nat Struct Mol Biol (2009) 1.98
ESCRT-III family members stimulate Vps4 ATPase activity directly or via Vta1. Dev Cell (2008) 1.91
Evolution of the multivesicular body ESCRT machinery; retention across the eukaryotic lineage. Traffic (2008) 1.86
Defining a pathway of communication from the C-terminal peptide binding domain to the N-terminal ATPase domain in a AAA protein. Mol Cell (2002) 1.82
Computational model of membrane fission catalyzed by ESCRT-III. PLoS Comput Biol (2009) 1.78
Structural basis for autoinhibition of ESCRT-III CHMP3. J Mol Biol (2008) 1.78
Ist1 regulates Vps4 localization and assembly. Mol Biol Cell (2007) 1.68
Essential role of hIST1 in cytokinesis. Mol Biol Cell (2009) 1.62
Biochemical analyses of human IST1 and its function in cytokinesis. Mol Biol Cell (2009) 1.57
Recognition of C-terminal amino acids in tubulin by pore loops in Spastin is important for microtubule severing. J Cell Biol (2007) 1.56
Role of the GYVG pore motif of HslU ATPase in protein unfolding and translocation for degradation by HslV peptidase. J Biol Chem (2005) 1.53
Structure and function of the ESCRT-II-III interface in multivesicular body biogenesis. Dev Cell (2009) 1.50
Novel interactions of ESCRT-III with LIP5 and VPS4 and their implications for ESCRT-III disassembly. Mol Biol Cell (2008) 1.46
Cell biology of the ESCRT machinery. Curr Opin Cell Biol (2009) 1.45
Assembly of the AAA ATPase Vps4 on ESCRT-III. Mol Biol Cell (2010) 1.43
A camel passes through the eye of a needle: protein unfolding activity of Clp ATPases. Mol Microbiol (2006) 1.43
The ESCRT machinery: new functions in viral and cellular biology. Biochem Soc Trans (2009) 1.40
The 'glutamate switch' provides a link between ATPase activity and ligand binding in AAA+ proteins. Nat Struct Mol Biol (2008) 1.38
Her4 and Her2/neu tyrosine kinase domains dimerize and activate in a reconstituted in vitro system. J Biol Chem (2009) 1.36
Cryo-EM structure of dodecameric Vps4p and its 2:1 complex with Vta1p. J Mol Biol (2008) 1.33
Polypeptide translocation by the AAA+ ClpXP protease machine. Chem Biol (2009) 1.32
Regulators of Vps4 ATPase activity at endosomes differentially influence the size and rate of formation of intralumenal vesicles. Mol Biol Cell (2010) 1.32
Structural basis of Ist1 function and Ist1-Did2 interaction in the multivesicular body pathway and cytokinesis. Mol Biol Cell (2009) 1.27
Defining the SNARE complex binding surface of alpha-SNAP: implications for SNARE complex disassembly. J Biol Chem (2003) 1.20
Biochemical and structural studies of yeast Vps4 oligomerization. J Mol Biol (2008) 1.15
Structural characterization of the ATPase reaction cycle of endosomal AAA protein Vps4. J Mol Biol (2007) 1.11
Vacuolar protein sorting: two different functional states of the AAA-ATPase Vps4p. J Mol Biol (2008) 1.09
Three-dimensional structure of AAA ATPase Vps4: advancing structural insights into the mechanisms of endosomal sorting and enveloped virus budding. Structure (2009) 1.08
Crystal structure and biophysical properties of a complex between the N-terminal SNARE region of SNAP25 and syntaxin 1a. J Biol Chem (2001) 1.07
Structure and function of ESCRT-III. Biochem Soc Trans (2009) 0.99
Nucleotide-dependent conformational changes and assembly of the AAA ATPase SKD1/VPS4B. Traffic (2008) 0.97
SNARE complex zero layer residues are not critical for N-ethylmaleimide-sensitive factor-mediated disassembly. J Biol Chem (2006) 0.91
Evolution and assembly of ESCRTs. Biochem Soc Trans (2009) 0.85
Role of a conserved pore residue in the formation of a prehydrolytic high substrate affinity state in the AAA+ chaperone ClpA. Biochemistry (2008) 0.82
Poly-L-lysine enhances the protein disaggregation activity of ClpB. FEBS Lett (2003) 0.81
Taking apart the endocytic machinery. J Cell Biol (2008) 0.80
Membrane budding and scission by the ESCRT machinery: it's all in the neck. Nat Rev Mol Cell Biol (2010) 4.29
The pathophysiological basis of dystonias. Nat Rev Neurosci (2008) 3.46
Structure/function analysis of four core ESCRT-III proteins reveals common regulatory role for extreme C-terminal domain. Traffic (2007) 2.76
Interaction of the mammalian endosomal sorting complex required for transport (ESCRT) III protein hSnf7-1 with itself, membranes, and the AAA+ ATPase SKD1. J Biol Chem (2005) 2.50
The hyh mutation uncovers roles for alpha Snap in apical protein localization and control of neural cell fate. Nat Genet (2004) 2.32
Distinct roles for the AAA ATPases NSF and p97 in the secretory pathway. Mol Biol Cell (2003) 2.09
TorsinA in the nuclear envelope. Proc Natl Acad Sci U S A (2004) 2.06
Inclusion body myopathy-associated mutations in p97/VCP impair endoplasmic reticulum-associated degradation. Hum Mol Genet (2005) 2.01
NSF ATPase and alpha-/beta-SNAPs disassemble the AMPA receptor-PICK1 complex. Neuron (2002) 1.83
Impaired protein aggregate handling and clearance underlie the pathogenesis of p97/VCP-associated disease. J Biol Chem (2008) 1.82
CHMP4B, a novel gene for autosomal dominant cataracts linked to chromosome 20q. Am J Hum Genet (2007) 1.65
LULL1 retargets TorsinA to the nuclear envelope revealing an activity that is impaired by the DYT1 dystonia mutation. Mol Biol Cell (2009) 1.47
Novel interactions of ESCRT-III with LIP5 and VPS4 and their implications for ESCRT-III disassembly. Mol Biol Cell (2008) 1.46
Transgenic expression of inclusion body myopathy associated mutant p97/VCP causes weakness and ubiquitinated protein inclusions in mice. Hum Mol Genet (2007) 1.44
TorsinA in PC12 cells: localization in the endoplasmic reticulum and response to stress. J Neurosci Res (2003) 1.42
Effects of genetic variations in the dystonia protein torsinA: identification of polymorphism at residue 216 as protein modifier. Hum Mol Genet (2006) 1.35
Luminal chloride-dependent activation of endosome calcium channels: patch clamp study of enlarged endosomes. J Biol Chem (2007) 1.28
Interaction of torsinA with its major binding partners is impaired by the dystonia-associated DeltaGAG deletion. J Biol Chem (2009) 1.26
Ubiquitin depletion and dominant-negative VPS4 inhibit rhabdovirus budding without affecting alphavirus budding. J Virol (2007) 1.21
Defining the SNARE complex binding surface of alpha-SNAP: implications for SNARE complex disassembly. J Biol Chem (2003) 1.20
The early onset dystonia protein torsinA interacts with kinesin light chain 1. J Biol Chem (2004) 1.16
Static retention of the lumenal monotopic membrane protein torsinA in the endoplasmic reticulum. EMBO J (2011) 1.00
TorsinB--perinuclear location and association with torsinA. J Neurochem (2004) 0.97
SNARE complex zero layer residues are not critical for N-ethylmaleimide-sensitive factor-mediated disassembly. J Biol Chem (2006) 0.91
p97 Is in a complex with cholera toxin and influences the transport of cholera toxin and related toxins to the cytoplasm. J Biol Chem (2005) 0.87
An essential and NSF independent role for α-SNAP in store-operated calcium entry. Elife (2013) 0.83
Sealed with a twist: complexin and the synaptic SNARE complex. Trends Neurosci (2002) 0.82
Stable isotope labeling with amino acids in cell culture based mass spectrometry approach to detect transient protein interactions using substrate trapping. Anal Chem (2011) 0.81
Cell-free reconstitution of multivesicular body formation and receptor sorting. Traffic (2010) 0.81
From the neuromuscular junction to cellular architecture and beyond--commentary on 30 years of imaging by John E. Heuser. Eur J Cell Biol (2004) 0.75