PubRank

Andre G Uitterlinden

Author PubWeight™ 329.36‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Biological, clinical and population relevance of 95 loci for blood lipids. Nature 2010 28.21
2 Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet 2011 13.25
3 Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature 2011 13.25
4 Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. Nat Genet 2008 12.32
5 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet 2012 11.09
6 Genome-wide analysis of genetic loci associated with Alzheimer disease. JAMA 2010 9.52
7 Common genetic determinants of vitamin D insufficiency: a genome-wide association study. Lancet 2010 8.89
8 Large-scale genotyping identifies 41 new loci associated with breast cancer risk. Nat Genet 2013 8.24
9 Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics. PLoS Genet 2008 6.22
10 New loci associated with kidney function and chronic kidney disease. Nat Genet 2010 5.58
11 Genomewide association studies of stroke. N Engl J Med 2009 5.29
12 Assessment of cumulative evidence on genetic associations: interim guidelines. Int J Epidemiol 2007 4.96
13 Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nat Genet 2012 4.73
14 Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis. Nat Genet 2009 4.38
15 A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Nat Genet 2012 4.37
16 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet 2014 4.13
17 Genome-wide association studies identify four ER negative-specific breast cancer risk loci. Nat Genet 2013 3.81
18 Meta-analysis identifies six new susceptibility loci for atrial fibrillation. Nat Genet 2012 3.71
19 Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels. Circulation 2011 3.68
20 Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet 2011 3.40
21 A road map for efficient and reliable human genome epidemiology. Nat Genet 2006 3.21
22 Genome-wide association analysis identifies three new breast cancer susceptibility loci. Nat Genet 2012 3.20
23 Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. Nat Genet 2011 3.18
24 Identification of genetic loci associated with Helicobacter pylori serologic status. JAMA 2013 3.15
25 Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. Nat Genet 2012 3.04
26 Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet 2013 2.92
27 The Generation R Study: design and cohort update 2012. Eur J Epidemiol 2012 2.84
28 Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium. Circulation 2010 2.78
29 Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors. Circ Cardiovasc Genet 2010 2.76
30 Large-scale analysis of association between GDF5 and FRZB variants and osteoarthritis of the hip, knee, and hand. Arthritis Rheum 2009 2.47
31 A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11. Hum Mol Genet 2012 2.45
32 Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium. Ann Neurol 2011 2.37
33 Genome-wide association study of migraine implicates a common susceptibility variant on 8q22.1. Nat Genet 2010 2.35
34 Genome-wide association study using extreme truncate selection identifies novel genes affecting bone mineral density and fracture risk. PLoS Genet 2011 2.34
35 Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases. PLoS Genet 2012 2.34
36 Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight. Nat Genet 2010 2.30
37 Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data. JAMA 2009 2.10
38 Three genome-wide association studies and a linkage analysis identify HERC2 as a human iris color gene. Am J Hum Genet 2008 2.09
39 Large-scale genomic studies reveal central role of ABO in sP-selectin and sICAM-1 levels. Hum Mol Genet 2010 2.05
40 A genome-wide association study of northwestern Europeans involves the C-type natriuretic peptide signaling pathway in the etiology of human height variation. Hum Mol Genet 2009 2.03
41 Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption. Proc Natl Acad Sci U S A 2011 2.01
42 Genome-wide association meta-analysis for total serum bilirubin levels. Hum Mol Genet 2009 1.96
43 Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction. Circulation 2011 1.96
44 A functional polymorphism in the catechol-O-methyltransferase gene is associated with osteoarthritis-related pain. Arthritis Rheum 2009 1.94
45 The Generation R Study Biobank: a resource for epidemiological studies in children and their parents. Eur J Epidemiol 2007 1.89
46 A genome-wide association study of optic disc parameters. PLoS Genet 2010 1.87
47 Genome-wide association study of smoking initiation and current smoking. Am J Hum Genet 2009 1.87
48 Polymorphisms in thyroid hormone pathway genes are associated with plasma TSH and iodothyronine levels in healthy subjects. J Clin Endocrinol Metab 2003 1.86
49 Genetic variation, C-reactive protein levels, and incidence of diabetes. Diabetes 2007 1.86
50 The Generation R Study: design and cohort update 2010. Eur J Epidemiol 2010 1.85
51 Association of genome-wide variation with the risk of incident heart failure in adults of European and African ancestry: a prospective meta-analysis from the cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium. Circ Cardiovasc Genet 2010 1.83
52 Common variants at 12q14 and 12q24 are associated with hippocampal volume. Nat Genet 2012 1.79
53 A genome-wide association study of acenocoumarol maintenance dosage. Hum Mol Genet 2009 1.78
54 Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease. Circulation 2013 1.77
55 Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22. Ann Rheum Dis 2010 1.75
56 Genetic variation at the phospholipid transfer protein locus affects its activity and high-density lipoprotein size and is a novel marker of cardiovascular disease susceptibility. Circulation 2010 1.75
57 The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis. PLoS Med 2013 1.70
58 Predicting human height by Victorian and genomic methods. Eur J Hum Genet 2009 1.69
59 Genome-wide association and functional follow-up reveals new loci for kidney function. PLoS Genet 2012 1.68
60 Novel genetic variants associated with lumbar disc degeneration in northern Europeans: a meta-analysis of 4600 subjects. Ann Rheum Dis 2012 1.66
61 Bone parameters across different types of hip osteoarthritis and their relationship to osteoporotic fracture risk. Arthritis Rheum 2013 1.65
62 Genome-wide association analysis identifies susceptibility loci for migraine without aura. Nat Genet 2012 1.64
63 A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease. Circ Cardiovasc Genet 2011 1.63
64 A variant in MCF2L is associated with osteoarthritis. Am J Hum Genet 2011 1.60
65 Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo. PLoS Genet 2010 1.57
66 The Generation R Study: design and cohort update until the age of 4 years. Eur J Epidemiol 2008 1.54
67 Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels. Hum Mol Genet 2010 1.53
68 Genomic variation associated with mortality among adults of European and African ancestry with heart failure: the cohorts for heart and aging research in genomic epidemiology consortium. Circ Cardiovasc Genet 2010 1.52
69 Homocysteine level is associated with aortic stiffness in elderly: cross-sectional results from the B-PROOF study. J Hypertens 2013 1.52
70 Common variants at 6q22 and 17q21 are associated with intracranial volume. Nat Genet 2012 1.51
71 Genome-wide association studies of MRI-defined brain infarcts: meta-analysis from the CHARGE Consortium. Stroke 2009 1.47
72 Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2. Arterioscler Thromb Vasc Biol 2014 1.45
73 The M235T polymorphism in the angiotensinogen gene is associated with the risk of malignant hypertension in white patients. J Hypertens 2007 1.44
74 Loci for regulation of bone mineral density in men and women identified by genome wide linkage scan: the FAMOS study. Hum Mol Genet 2005 1.42
75 Association of novel genetic Loci with circulating fibrinogen levels: a genome-wide association study in 6 population-based cohorts. Circ Cardiovasc Genet 2009 1.41
76 Common genetic determinants of intraocular pressure and primary open-angle glaucoma. PLoS Genet 2012 1.33
77 A functional variant in the CFI gene confers a high risk of age-related macular degeneration. Nat Genet 2013 1.29
78 Genome-wide association and functional studies identify the DOT1L gene to be involved in cartilage thickness and hip osteoarthritis. Proc Natl Acad Sci U S A 2012 1.28
79 Polymorphisms near IL28B and serologic response to peginterferon in HBeAg-positive patients with chronic hepatitis B. Gastroenterology 2011 1.28
80 The Generation R Study: Biobank update 2015. Eur J Epidemiol 2014 1.26
81 Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation. Blood 2012 1.26
82 Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies. Circ Cardiovasc Genet 2011 1.26
83 Glucocorticoid receptor gene and risk of cardiovascular disease. Arch Intern Med 2008 1.25
84 Genetic determination of human facial morphology: links between cleft-lips and normal variation. Eur J Hum Genet 2011 1.17
85 Influence of LRP5 polymorphisms on normal variation in BMD. J Bone Miner Res 2004 1.14
86 Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function. Hum Mol Genet 2012 1.14
87 Interleukin-6 receptor pathways in abdominal aortic aneurysm. Eur Heart J 2012 1.12
88 Integrating genetic, transcriptional, and functional analyses to identify 5 novel genes for atrial fibrillation. Circulation 2014 1.11
89 Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease. Am J Clin Nutr 2013 1.08
90 The Generation R Study: a review of design, findings to date, and a study of the 5-HTTLPR by environmental interaction from fetal life onward. J Am Acad Child Adolesc Psychiatry 2012 1.06
91 Dopaminergic, serotonergic, and oxytonergic candidate genes associated with infant attachment security and disorganization? In search of main and interaction effects. J Child Psychol Psychiatry 2011 1.05
92 Genetic predictors of fibrin D-dimer levels in healthy adults. Circulation 2011 1.05
93 Complement component C3 and risk of age-related macular degeneration. Ophthalmology 2009 1.05
94 A new polymorphism in the type II deiodinase gene is associated with circulating thyroid hormone parameters. Am J Physiol Endocrinol Metab 2005 1.04
95 Genetics of cortisol secretion and depressive symptoms: a candidate gene and genome wide association approach. Psychoneuroendocrinology 2011 1.03
96 A genome-wide association study of early-onset breast cancer identifies PFKM as a novel breast cancer gene and supports a common genetic spectrum for breast cancer at any age. Cancer Epidemiol Biomarkers Prev 2014 1.03
97 A study of the SORL1 gene in Alzheimer's disease and cognitive function. J Alzheimers Dis 2009 1.02
98 Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium. Hum Mol Genet 2014 1.02
99 Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations. PLoS Genet 2013 1.02
100 Genome-wide study links MTMR7 gene to variant Creutzfeldt-Jakob risk. Neurobiol Aging 2011 0.95
101 A common polymorphism renders the luteinizing hormone receptor protein more active by improving signal peptide function and predicts adverse outcome in breast cancer patients. J Clin Endocrinol Metab 2006 0.95
102 Mapping of gene expression reveals CYP27A1 as a susceptibility gene for sporadic ALS. PLoS One 2012 0.95
103 Genetic determinants of treatment benefit of the angiotensin-converting enzyme-inhibitor perindopril in patients with stable coronary artery disease. Eur Heart J 2010 0.94
104 Identification of a candidate gene for astigmatism. Invest Ophthalmol Vis Sci 2013 0.92
105 A large genome scan for rare CNVs in amyotrophic lateral sclerosis. Hum Mol Genet 2010 0.92
106 Nucleotide excision DNA repair is associated with age-related vascular dysfunction. Circulation 2012 0.90
107 Genome-wide profiling of blood pressure in adults and children. Hypertension 2011 0.89
108 PTHR1 polymorphisms influence BMD variation through effects on the growing skeleton. Calcif Tissue Int 2007 0.87
109 CYP1A2 and coffee intake and the modifying effect of sex, age, and smoking. Am J Clin Nutr 2012 0.86
110 The effect of catechol-O-methyltransferase Met/Val functional polymorphism on smoking cessation: retrospective and prospective analyses in a cohort study. Pharmacogenet Genomics 2009 0.85
111 Low prevalence of NOD2 SNPs in Behçet's disease suggests protective association in Caucasians. Rheumatology (Oxford) 2009 0.85
112 A genetic variant in the seed region of miR-4513 shows pleiotropic effects on lipid and glucose homeostasis, blood pressure, and coronary artery disease. Hum Mutat 2014 0.85
113 Polymorphisms in the interleukin 6 and transforming growth factor beta1 gene and risk of dementia. The Rotterdam Study. Neurosci Lett 2006 0.83
114 Association of HSP70 and its co-chaperones with Alzheimer's disease. J Alzheimers Dis 2011 0.83
115 Variation at the ANP32A gene is associated with risk of hip osteoarthritis in women. Arthritis Rheum 2009 0.82
116 A polymorphism in type I deiodinase is associated with circulating free insulin-like growth factor I levels and body composition in humans. J Clin Endocrinol Metab 2004 0.82
117 Common variants in Mendelian kidney disease genes and their association with renal function. J Am Soc Nephrol 2013 0.82
118 Breast-feeding modifies the association of PPARgamma2 polymorphism Pro12Ala with growth in early life: the Generation R Study. Diabetes 2009 0.81
119 Genetic architecture of open angle glaucoma and related determinants. J Med Genet 2010 0.81
120 Associations of polymorphisms of eight muscle- or metabolism-related genes with performance in Mount Olympus marathon runners. J Appl Physiol (1985) 2009 0.81
121 A pharmacogenetic analysis of determinants of hypertension and blood pressure response to angiotensin-converting enzyme inhibitor therapy in patients with vascular disease and healthy individuals. J Hypertens 2011 0.81
122 Efficient strategy for detecting gene × gene joint action and its application in schizophrenia. Genet Epidemiol 2013 0.80
123 Genetic loci for retinal arteriolar microcirculation. PLoS One 2013 0.80
124 A genetic epidemiologic study of candidate genes involved in the optic nerve head morphology. Invest Ophthalmol Vis Sci 2012 0.80
125 Mendelian randomization study of interleukin-6 in chronic obstructive pulmonary disease. Respiration 2011 0.79
126 Effects of 2-year vitamin B12 and folic acid supplementation in hyperhomocysteinemic elderly on arterial stiffness and cardiovascular outcomes within the B-PROOF trial. J Hypertens 2015 0.78
127 A genetic risk score for thyroid peroxidase antibodies associates with clinical thyroid disease in community-based populations. J Clin Endocrinol Metab 2015 0.78
128 Type 2 diabetes gene TCF7L2 polymorphism is not associated with fetal and postnatal growth in two birth cohort studies. BMC Med Genet 2009 0.78
129 Genome-wide association study of retinopathy in individuals without diabetes. PLoS One 2013 0.78
130 International Genome-Wide Association Study Consortium Identifies Novel Loci Associated With Blood Pressure in Children and Adolescents. Circ Cardiovasc Genet 2016 0.77
131 Corrigendum: Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine. Nat Genet 2016 0.77
132 Oscillometry and applanation tonometry measurements in older individuals with elevated levels of arterial stiffness. Blood Press Monit 2013 0.76
133 Association of heat shock proteins with Parkinson's disease. Eur J Epidemiol 2011 0.76
134 Finger length pattern as a biomarker for osteoarthritis and chronic joint pain: a population-based study and meta-analysis after systematic review. Arthritis Care Res (Hoboken) 2014 0.76
135 Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis. Circ Cardiovasc Genet 2016 0.75
136 Vitamin D and retinal microvascular damage: The Rotterdam Study. Medicine (Baltimore) 2016 0.75
137 Correction: Susceptibility to chronic mucus hypersecretion, a genome wide association study. PLoS One 2015 0.75
138 Erratum: Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation. Nat Genet 2017 0.75
139 Corrigendum: 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function. Sci Rep 2017 0.75
140 Lower sex hormone levels are associated with more chronic musculoskeletal pain in community-dwelling elderly women. Pain 2016 0.75
141 Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS. Sci Transl Med 2022 0.75