Published in Genome Res on November 06, 2012
Retrotransposons and pseudogenes regulate mRNAs and lncRNAs via the piRNA pathway in the germline. Genome Res (2014) 1.07
piRNAs derived from ancient viral processed pseudogenes as transgenerational sequence-specific immune memory in mammals. RNA (2015) 0.88
shRNA off-target effects in vivo: impaired endogenous siRNA expression and spermatogenic defects. PLoS One (2015) 0.80
Guardian small RNAs and sex determination. RNA Biol (2014) 0.79
The small RNA content of human sperm reveals pseudogene-derived piRNAs complementary to protein-coding genes. RNA (2015) 0.78
Endogenous non-retroviral RNA virus elements evidence a novel type of antiviral immunity. Mob Genet Elements (2016) 0.75
Artificial "ping-pong" cascade of PIWI-interacting RNA in silkworm cells. RNA (2016) 0.75
Characterization of piRNAs across postnatal development in mouse brain. Sci Rep (2016) 0.75
Intact piRNA pathway prevents L1 mobilization in male meiosis. Proc Natl Acad Sci U S A (2017) 0.75
Initial sequencing and comparative analysis of the mouse genome. Nature (2002) 96.15
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature (1998) 72.56
SeqMap: mapping massive amount of oligonucleotides to the genome. Bioinformatics (2008) 24.32
Biogenesis of small RNAs in animals. Nat Rev Mol Cell Biol (2009) 19.99
Discrete small RNA-generating loci as master regulators of transposon activity in Drosophila. Cell (2007) 18.35
MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies. Nat Cell Biol (2005) 12.12
Mobile elements: drivers of genome evolution. Science (2004) 11.78
A distinct small RNA pathway silences selfish genetic elements in the germline. Science (2006) 11.63
A slicer-mediated mechanism for repeat-associated siRNA 5' end formation in Drosophila. Science (2007) 10.73
A germline-specific class of small RNAs binds mammalian Piwi proteins. Nature (2006) 9.88
The Piwi-piRNA pathway provides an adaptive defense in the transposon arms race. Science (2007) 9.36
A novel class of small RNAs bind to MILI protein in mouse testes. Nature (2006) 8.80
Disruption of overlapping transcripts in the ROSA beta geo 26 gene trap strain leads to widespread expression of beta-galactosidase in mouse embryos and hematopoietic cells. Proc Natl Acad Sci U S A (1997) 8.35
Characterization of the piRNA complex from rat testes. Science (2006) 7.86
Developmentally regulated piRNA clusters implicate MILI in transposon control. Science (2007) 7.68
MIWI2 is essential for spermatogenesis and repression of transposons in the mouse male germline. Dev Cell (2007) 7.66
A piRNA pathway primed by individual transposons is linked to de novo DNA methylation in mice. Mol Cell (2008) 6.35
A novel class of small RNAs in mouse spermatogenic cells. Genes Dev (2006) 5.85
miwi, a murine homolog of piwi, encodes a cytoplasmic protein essential for spermatogenesis. Dev Cell (2002) 5.85
PIWI-interacting small RNAs: the vanguard of genome defence. Nat Rev Mol Cell Biol (2011) 5.59
DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes. Genes Dev (2008) 5.58
Mili, a mammalian member of piwi family gene, is essential for spermatogenesis. Development (2004) 5.47
Transcriptional disruption by the L1 retrotransposon and implications for mammalian transcriptomes. Nature (2004) 5.15
Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes. Genes Dev (2006) 4.97
Biogenesis and germline functions of piRNAs. Development (2007) 4.37
A novel reporter mouse strain that expresses enhanced green fluorescent protein upon Cre-mediated recombination. FEBS Lett (2000) 4.03
Maternal and zygotic Dnmt1 are necessary and sufficient for the maintenance of DNA methylation imprints during preimplantation development. Genes Dev (2008) 2.99
MIWI associates with translational machinery and PIWI-interacting RNAs (piRNAs) in regulating spermatogenesis. Proc Natl Acad Sci U S A (2006) 2.80
Conserved themes in small-RNA-mediated transposon control. Trends Cell Biol (2008) 2.67
Role for piRNAs and noncoding RNA in de novo DNA methylation of the imprinted mouse Rasgrf1 locus. Science (2011) 2.17
Miwi catalysis is required for piRNA amplification-independent LINE1 transposon silencing. Nature (2011) 2.11
Cytoplasmic compartmentalization of the fetal piRNA pathway in mice. PLoS Genet (2009) 2.11
Two mouse piwi-related genes: miwi and mili. Mech Dev (2001) 2.05
3' end formation of PIWI-interacting RNAs in vitro. Mol Cell (2011) 2.05
The endonuclease activity of Mili fuels piRNA amplification that silences LINE1 elements. Nature (2011) 1.77
Adaptation to P element transposon invasion in Drosophila melanogaster. Cell (2011) 1.76
Interplay of PIWI/Argonaute protein MIWI and kinesin KIF17b in chromatoid bodies of male germ cells. J Cell Sci (2006) 1.52
Ultrastructural characterization of spermatogenesis and its evolutionary conservation in the germline: germinal granules in mammals. Mol Cell Endocrinol (2008) 1.51
piRNAs mediate posttranscriptional retroelement silencing and localization to pi-bodies in the Drosophila germline. J Cell Biol (2009) 1.46
Production of artificial piRNAs in flies and mice. RNA (2011) 1.37
Functional redundancy among Nanos proteins and a distinct role of Nanos2 during male germ cell development. Development (2006) 1.36
piRNAs and their involvement in male germline development in mice. Dev Growth Differ (2012) 1.31
Limiting Ago protein restricts RNAi and microRNA biogenesis during early development in Xenopus laevis. Genes Dev (2011) 1.30
Rapid repetitive element-mediated expansion of piRNA clusters in mammalian evolution. Proc Natl Acad Sci U S A (2009) 1.14
Mice deficient for a small cluster of Piwi-interacting RNAs implicate Piwi-interacting RNAs in transposon control. Biol Reprod (2008) 1.05
Overexpression of ubiquitin carboxyl-terminal hydrolase L1 arrests spermatogenesis in transgenic mice. Mol Reprod Dev (2006) 0.97
Identification of presomitic mesoderm (PSM)-specific Mesp1 enhancer and generation of a PSM-specific Mesp1/Mesp2-null mouse using BAC-based rescue technology. Mech Dev (2008) 0.87
Analysis of small RNA profiles during development. Methods Enzymol (2007) 0.83
Comparative metagenomics revealed commonly enriched gene sets in human gut microbiomes. DNA Res (2007) 13.08
Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes. Nature (2008) 10.11
A novel class of small RNAs bind to MILI protein in mouse testes. Nature (2006) 8.80
The Physcomitrella genome reveals evolutionary insights into the conquest of land by plants. Science (2007) 8.12
The amphioxus genome and the evolution of the chordate karyotype. Nature (2008) 8.03
Characterization of the piRNA complex from rat testes. Science (2006) 7.86
Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting. Nature (2004) 7.42
The medaka draft genome and insights into vertebrate genome evolution. Nature (2007) 5.77
Size-selective loosening of the blood-brain barrier in claudin-5-deficient mice. J Cell Biol (2003) 5.74
5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming. Nat Commun (2011) 5.66
DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes. Genes Dev (2008) 5.58
Mili, a mammalian member of piwi family gene, is essential for spermatogenesis. Development (2004) 5.47
A large-scale full-length cDNA analysis to explore the budding yeast transcriptome. Proc Natl Acad Sci U S A (2006) 5.24
Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes. Genes Dev (2006) 4.97
A map of rice genome variation reveals the origin of cultivated rice. Nature (2012) 4.92
ZO-1 and ZO-2 independently determine where claudins are polymerized in tight-junction strand formation. Cell (2006) 4.61
Clinical significance of circulating tumor cells, including cancer stem-like cells, in peripheral blood for recurrence and prognosis in patients with Dukes' stage B and C colorectal cancer. J Clin Oncol (2011) 4.48
Targets and dynamics of promoter DNA methylation during early mouse development. Nat Genet (2010) 4.27
Negligible immunogenicity of terminally differentiated cells derived from induced pluripotent or embryonic stem cells. Nature (2013) 4.19
Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas. J Clin Invest (2004) 3.92
Comparative analysis of chimpanzee and human Y chromosomes unveils complex evolutionary pathway. Nat Genet (2006) 3.76
Notch-RBP-J signaling is involved in cell fate determination of marginal zone B cells. Nat Immunol (2002) 3.75
CLASP1 and CLASP2 bind to EB1 and regulate microtubule plus-end dynamics at the cell cortex. J Cell Biol (2005) 3.54
PGC7/Stella protects against DNA demethylation in early embryogenesis. Nat Cell Biol (2006) 3.54
Role of the Dnmt3 family in de novo methylation of imprinted and repetitive sequences during male germ cell development in the mouse. Hum Mol Genet (2007) 3.27
Using the Acropora digitifera genome to understand coral responses to environmental change. Nature (2011) 3.26
The mechanism selecting the guide strand from small RNA duplexes is different among argonaute proteins. Plant Cell Physiol (2008) 3.15
Selective molecular imaging of viable cancer cells with pH-activatable fluorescence probes. Nat Med (2008) 3.15
Acute toxicity and biodistribution of different sized titanium dioxide particles in mice after oral administration. Toxicol Lett (2006) 3.06
Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells. J Cell Biol (2005) 3.05
Maternal and zygotic Dnmt1 are necessary and sufficient for the maintenance of DNA methylation imprints during preimplantation development. Genes Dev (2008) 2.99
SNP and haplotype mapping for genetic analysis in the rat. Nat Genet (2008) 2.96
The TDRD9-MIWI2 complex is essential for piRNA-mediated retrotransposon silencing in the mouse male germline. Dev Cell (2009) 2.96
Correlations between lymph node metastasis and depth of submucosal invasion in submucosal invasive colorectal carcinoma: a Japanese collaborative study. J Gastroenterol (2004) 2.88
Construction and analysis of a human-chimpanzee comparative clone map. Science (2002) 2.83
A broadly conserved pathway generates 3'UTR-directed primary piRNAs. Curr Biol (2009) 2.69
Contribution of Asian mouse subspecies Mus musculus molossinus to genomic constitution of strain C57BL/6J, as defined by BAC-end sequence-SNP analysis. Genome Res (2004) 2.55
PGC7 binds histone H3K9me2 to protect against conversion of 5mC to 5hmC in early embryos. Nature (2012) 2.38
Stella is a maternal effect gene required for normal early development in mice. Curr Biol (2003) 2.38
Impeding Xist expression from the active X chromosome improves mouse somatic cell nuclear transfer. Science (2010) 2.34
Dynamic stage-specific changes in imprinted differentially methylated regions during early mammalian development and prevalence of non-CpG methylation in oocytes. Development (2011) 2.28
Complete genome of the uncultured Termite Group 1 bacteria in a single host protist cell. Proc Natl Acad Sci U S A (2008) 2.21
Sequence analysis of the genome of an oil-bearing tree, Jatropha curcas L. DNA Res (2010) 2.19
The PTEN/PI3K pathway governs normal vascular development and tumor angiogenesis. Genes Dev (2005) 2.18
Genome sequence of an Australian kangaroo, Macropus eugenii, provides insight into the evolution of mammalian reproduction and development. Genome Biol (2011) 2.18
Role for piRNAs and noncoding RNA in de novo DNA methylation of the imprinted mouse Rasgrf1 locus. Science (2011) 2.17
Critical roles of Pten in B cell homeostasis and immunoglobulin class switch recombination. J Exp Med (2003) 2.16
Synergistic function of DNA methyltransferases Dnmt3a and Dnmt3b in the methylation of Oct4 and Nanog. Mol Cell Biol (2007) 2.15
Chromosome-wide assessment of replication timing for human chromosomes 11q and 21q: disease-related genes in timing-switch regions. Hum Mol Genet (2002) 2.12
Unregulated expression of the imprinted genes H19 and Igf2r in mouse uniparental fetuses. J Biol Chem (2002) 2.01
Pluripotential competence of cells associated with Nanog activity. Mech Dev (2005) 2.01
Identification of RNF213 as a susceptibility gene for moyamoya disease and its possible role in vascular development. PLoS One (2011) 2.01
Mutations for Gaucher disease confer high susceptibility to Parkinson disease. Arch Neurol (2009) 2.00
Tsix silences Xist through modification of chromatin structure. Dev Cell (2005) 1.97
Genome of an endosymbiont coupling N2 fixation to cellulolysis within protist cells in termite gut. Science (2008) 1.96
Clinicopathological and prognostic value of microRNA-21 and microRNA-155 in colorectal cancer. Oncology (2011) 1.96
Multi-PDZ domain protein 1 (MUPP1) is concentrated at tight junctions through its possible interaction with claudin-1 and junctional adhesion molecule. J Biol Chem (2001) 1.96
External antigen uptake by Langerhans cells with reorganization of epidermal tight junction barriers. J Exp Med (2009) 1.95
MITOPLD is a mitochondrial protein essential for nuage formation and piRNA biogenesis in the mouse germline. Dev Cell (2011) 1.94
Oncogenic BRAF(V600E) promotes stromal cell-mediated immunosuppression via induction of interleukin-1 in melanoma. Clin Cancer Res (2012) 1.94
Establishment and characterization of cultured epithelial cells lacking expression of ZO-1. J Biol Chem (2004) 1.94
Identification of PGC7, a new gene expressed specifically in preimplantation embryos and germ cells. Mech Dev (2002) 1.94
MILI, a PIWI-interacting RNA-binding protein, is required for germ line stem cell self-renewal and appears to positively regulate translation. J Biol Chem (2008) 1.93
Epigallocatechin gallate, the main component of tea polyphenol, binds to CD4 and interferes with gp120 binding. J Allergy Clin Immunol (2003) 1.87