Published in Proc Natl Acad Sci U S A on March 04, 2013
Mammary stem cells and the differentiation hierarchy: current status and perspectives. Genes Dev (2014) 1.86
The proper criteria for identification and sorting of very small embryonic-like stem cells, and some nomenclature issues. Stem Cells Dev (2014) 1.70
A continuous molecular roadmap to iPSC reprogramming through progression analysis of single-cell mass cytometry. Cell Stem Cell (2015) 1.67
Hallmarks of pluripotency. Nature (2015) 1.60
Taxonomy of breast cancer based on normal cell phenotype predicts outcome. J Clin Invest (2014) 1.58
Therapeutic Potential of Stem Cells from Human Exfoliated Deciduous Teeth in Models of Acute Kidney Injury. PLoS One (2015) 1.42
Rethinking differentiation: stem cells, regeneration, and plasticity. Cell (2014) 1.41
Dedifferentiation and reprogramming: origins of cancer stem cells. EMBO Rep (2014) 1.16
Mammary morphogenesis and regeneration require the inhibition of EMT at terminal end buds by Ovol2 transcriptional repressor. Dev Cell (2014) 1.03
Loss of CD73-mediated actin polymerization promotes endometrial tumor progression. J Clin Invest (2015) 0.94
Epigenetic and transcriptional determinants of the human breast. Nat Commun (2015) 0.89
Expression of the Pluripotency Transcription Factor OCT4 in the Normal and Aberrant Mammary Gland. Front Oncol (2013) 0.88
Gene expression in breastmilk cells is associated with maternal and infant characteristics. Sci Rep (2015) 0.84
Profiling gene promoter occupancy of Sox2 in two phenotypically distinct breast cancer cell subsets using chromatin immunoprecipitation and genome-wide promoter microarrays. Breast Cancer Res (2014) 0.83
Models of breast morphogenesis based on localization of stem cells in the developing mammary lobule. Stem Cell Reports (2015) 0.83
p53 loss increases the osteogenic differentiation of bone marrow stromal cells. Stem Cells (2015) 0.83
Wip1 phosphatase in breast cancer. Oncogene (2014) 0.83
At the dawn of a new discovery: the potential of breast milk stem cells. Adv Nutr (2014) 0.82
A co-culture genome-wide RNAi screen with mammary epithelial cells reveals transmembrane signals required for growth and differentiation. Breast Cancer Res (2015) 0.81
Phenotypic plasticity in normal breast derived epithelial cells. BMC Cell Biol (2014) 0.80
Senescence-Inflammatory Regulation of Reparative Cellular Reprogramming in Aging and Cancer. Front Cell Dev Biol (2017) 0.80
Pluripotency Genes and Their Functions in the Normal and Aberrant Breast and Brain. Int J Mol Sci (2015) 0.80
Triple negative breast cancers comprise a highly tumorigenic cell subpopulation detectable by its high responsiveness to a Sox2 regulatory region 2 (SRR2) reporter. Oncotarget (2015) 0.78
Of Mice and Women: A Comparative Tissue Biology Perspective of Breast Stem Cells and Differentiation. J Mammary Gland Biol Neoplasia (2015) 0.77
Changes in human pluripotent stem cell gene expression after genotoxic stress exposures. World J Stem Cells (2014) 0.77
Bidirectional interconversion of stem and non-stem cancer cell populations: A reassessment of theoretical models for tumor heterogeneity. Mol Cell Oncol (2015) 0.77
A mystery unraveled: nontumorigenic pluripotent stem cells in human adult tissues. Expert Opin Biol Ther (2014) 0.77
Molecular expression of vascular endothelial growth factor, prokineticin receptor-1 and other biomarkers in infiltrating canalicular carcinoma of the breast. Oncol Lett (2016) 0.76
Induction of multipotency in umbilical cord-derived mesenchymal stem cells cultivated under suspension conditions. Cell Stress Chaperones (2014) 0.75
SOX2, OCT3/4 and NANOG expression and cellular plasticity in rare human somatic cells requires CD73. Cell Signal (2016) 0.75
Stem cells news update: a personal perspective. Balkan J Med Genet (2013) 0.75
Cell cycle proliferation decisions: the impact of single cell analyses. FEBS J (2016) 0.75
Cell therapy in Brazil: time for reflection. Rev Bras Hematol Hemoter (2013) 0.75
Epigenetic Reprogramming of Lineage-Committed Human Mammary Epithelial Cells Requires DNMT3A and Loss of DOT1L. Stem Cell Reports (2017) 0.75
Unraveling cell-to-cell signaling networks with chemical biology. Nat Chem Biol (2017) 0.75
Matrix elasticity directs stem cell lineage specification. Cell (2006) 43.00
In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells. Genes Dev (2003) 20.77
Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells. Nature (2003) 14.35
The NIH Roadmap Epigenomics Mapping Consortium. Nat Biotechnol (2010) 13.99
The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus. Nature (1999) 12.60
Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell. Cell (2001) 12.42
Direct isolation of human central nervous system stem cells. Proc Natl Acad Sci U S A (2000) 10.88
Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers. Nat Med (2009) 10.88
Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo. Nat Biotechnol (2008) 10.60
Isolation of amniotic stem cell lines with potential for therapy. Nat Biotechnol (2007) 9.67
Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells. Proc Natl Acad Sci U S A (1992) 8.69
Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis. Nat Med (2005) 8.01
Reconstruction of functionally normal and malignant human breast tissues in mice. Proc Natl Acad Sci U S A (2004) 7.96
The functions of E(Z)/EZH2-mediated methylation of lysine 27 in histone H3. Curr Opin Genet Dev (2004) 7.89
AC133, a novel marker for human hematopoietic stem and progenitor cells. Blood (1997) 7.84
The Polycomb Ezh2 methyltransferase regulates muscle gene expression and skeletal muscle differentiation. Genes Dev (2004) 6.20
Characterization of bipotent mammary epithelial progenitor cells in normal adult human breast tissue. Breast Cancer Res Treat (2001) 3.96
Characterization and enrichment of cardiomyocytes derived from human embryonic stem cells. Circ Res (2002) 3.69
Endothelial cells derived from human embryonic stem cells. Proc Natl Acad Sci U S A (2002) 3.66
A method for quantifying normal human mammary epithelial stem cells with in vivo regenerative ability. Nat Med (2008) 3.64
shRNA knockdown of Bmi-1 reveals a critical role for p21-Rb pathway in NSC self-renewal during development. Cell Stem Cell (2007) 3.40
The interplay of matrix metalloproteinases, morphogens and growth factors is necessary for branching of mammary epithelial cells. Development (2001) 3.04
Reconstruction of human mammary tissues in a mouse model. Nat Protoc (2006) 2.03
Tumor suppressor p16INK4A regulates polycomb-mediated DNA hypermethylation in human mammary epithelial cells. J Biol Chem (2006) 1.93
Paneth cells in intestinal homeostasis and tissue injury. PLoS One (2012) 1.57
Serum-free derivation of human embryonic stem cell lines on human placental fibroblast feeders. Fertil Steril (2005) 1.39
Human neural crest cells display molecular and phenotypic hallmarks of stem cells. Hum Mol Genet (2008) 1.23
Osseous metaplasia in a tubular adenoma of the colon. J Clin Pathol (2005) 1.07
Intracranial ectopic pancreatic tissue. Islets (2010) 0.95
Ectopic liver nodules: a rare finding during cholecystectomy. G Chir (2011) 0.94
The mammary gland microenvironment directs progenitor cell fate in vivo. Int J Cell Biol (2011) 0.85
The clonal and mutational evolution spectrum of primary triple-negative breast cancers. Nature (2012) 11.91
TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia. Science (2004) 10.23
Blockade of TGF-beta inhibits mammary tumor cell viability, migration, and metastases. J Clin Invest (2002) 4.64
Biomarker expression and risk of subsequent tumors after initial ductal carcinoma in situ diagnosis. J Natl Cancer Inst (2010) 4.57
Abrogated response to cellular stress identifies DCIS associated with subsequent tumor events and defines basal-like breast tumors. Cancer Cell (2007) 3.44
Basal subtype and MAPK/ERK kinase (MEK)-phosphoinositide 3-kinase feedback signaling determine susceptibility of breast cancer cells to MEK inhibition. Cancer Res (2009) 3.14
Sustained induction of epithelial to mesenchymal transition activates DNA methylation of genes silenced in basal-like breast cancers. Proc Natl Acad Sci U S A (2008) 2.53
CD36 repression activates a multicellular stromal program shared by high mammographic density and tumor tissues. Cancer Discov (2012) 2.51
p16(INK4a) prevents centrosome dysfunction and genomic instability in primary cells. PLoS Biol (2006) 2.39
Methylation of p16(INK4a) promoters occurs in vivo in histologically normal human mammary epithelia. Cancer Res (2003) 2.03
Tumor suppressor p16INK4A regulates polycomb-mediated DNA hypermethylation in human mammary epithelial cells. J Biol Chem (2006) 1.93
Overexpression of HER2 (erbB2) in human breast epithelial cells unmasks transforming growth factor beta-induced cell motility. J Biol Chem (2004) 1.72
Histologically normal human mammary epithelia with silenced p16(INK4a) overexpress COX-2, promoting a premalignant program. Cancer Cell (2004) 1.66
DNA hypomethylation within specific transposable element families associates with tissue-specific enhancer landscape. Nat Genet (2013) 1.64
Dual role of transforming growth factor beta in mammary tumorigenesis and metastatic progression. Clin Cancer Res (2005) 1.62
Ionizing radiation predisposes nonmalignant human mammary epithelial cells to undergo transforming growth factor beta induced epithelial to mesenchymal transition. Cancer Res (2007) 1.60
An analogy between the evolution of drug resistance in bacterial communities and malignant tissues. Nat Rev Cancer (2011) 1.58
Tumor microenvironment and progression. J Surg Oncol (2011) 1.54
Novel interstitial 2.6 Mb deletion on 9q21 associated with multiple congenital anomalies. Am J Med Genet A (2014) 1.47
p16(INK4a) expression and breast cancer risk in women with atypical hyperplasia. Cancer Prev Res (Phila) (2011) 1.45
Clinical utility of LC3 and p62 immunohistochemistry in diagnosis of drug-induced autophagic vacuolar myopathies: a case-control study. PLoS One (2012) 1.43
Dermatomyositis with inclusion body myositis pathology. Muscle Nerve (2009) 1.39
Functional DNA methylation differences between tissues, cell types, and across individuals discovered using the M&M algorithm. Genome Res (2013) 1.33
A physical sciences network characterization of non-tumorigenic and metastatic cells. Sci Rep (2013) 1.33
No paradox, no progress: inverse cancer comorbidity in people with other complex diseases. Lancet Oncol (2011) 1.30
Identification of Siglec-9 as the receptor for MUC16 on human NK cells, B cells, and monocytes. Mol Cancer (2010) 1.30
Simulating properties of in vitro epithelial cell morphogenesis. PLoS Comput Biol (2006) 1.24
Quantitative genetic background of the host influences gut microbiomes in chickens. Sci Rep (2013) 1.20
Rapamycin potentiates transforming growth factor beta-induced growth arrest in nontransformed, oncogene-transformed, and human cancer cells. Mol Cell Biol (2002) 1.18
p38 regulates cyclooxygenase-2 in human mammary epithelial cells and is activated in premalignant tissue. Cancer Res (2005) 1.15
Neuronal activity regulates astrocytic Nrf2 signaling. Proc Natl Acad Sci U S A (2013) 1.13
p16INK4a modulates p53 in primary human mammary epithelial cells. Cancer Res (2006) 1.13
Breast fibroblasts modulate early dissemination, tumorigenesis, and metastasis through alteration of extracellular matrix characteristics. Neoplasia (2013) 1.11
Distinct distribution of specific members of protein 4.1 gene family in the mouse nephron. Kidney Int (2003) 1.07
The impact of diabetes on patient outcomes after ankle fracture. J Bone Joint Surg Am (2005) 1.06
U-Series dating of Liujiang hominid site in Guangxi, Southern China. J Hum Evol (2002) 1.06
MUC16 provides immune protection by inhibiting synapse formation between NK and ovarian tumor cells. Mol Cancer (2010) 1.06
Morphologically normal-appearing mammary epithelial cells obtained from high-risk women exhibit methylation silencing of INK4a/ARF. Clin Cancer Res (2007) 1.05
Complex formation with the Type B gamma-aminobutyric acid receptor affects the expression and signal transduction of the extracellular calcium-sensing receptor. Studies with HEK-293 cells and neurons. J Biol Chem (2007) 1.04
Primary cilia regulate branching morphogenesis during mammary gland development. Curr Biol (2010) 1.03
Graphical methods for quantifying macromolecules through bright field imaging. Bioinformatics (2008) 1.02
Plasmid-templated shape control of condensed DNA-block copolymer nanoparticles. Adv Mater (2012) 1.02
Infant botulism, type F, presenting at 54 hours of life. Pediatr Neurol (2005) 1.02
Cyclooxygenase-2 expression is related to nuclear grade in ductal carcinoma in situ and is increased in its normal adjacent epithelium. Cancer Res (2003) 1.00
Cell motility and drug gradients in the emergence of resistance to chemotherapy. Proc Natl Acad Sci U S A (2013) 0.99
Cell-extrinsic consequences of epithelial stress: activation of protumorigenic tissue phenotypes. Breast Cancer Res (2012) 0.97
Evaluation of epidermal growth factor receptor (EGFR) by chromogenic in situ hybridization (CISH) and immunohistochemistry (IHC) in archival gliomas using bright-field microscopy. Diagn Mol Pathol (2004) 0.97
Human mammary cancer progression model recapitulates methylation events associated with breast premalignancy. Breast Cancer Res (2009) 0.97
Klotho endows hepatoma cells with resistance to anoikis via VEGFR2/PAK1 activation in hepatocellular carcinoma. PLoS One (2013) 0.95
Type B gamma-aminobutyric acid receptors modulate the function of the extracellular Ca2+-sensing receptor and cell differentiation in murine growth plate chondrocytes. Endocrinology (2007) 0.95
Comparative utility of LC3, p62 and TDP-43 immunohistochemistry in differentiation of inclusion body myositis from polymyositis and related inflammatory myopathies. Acta Neuropathol Commun (2013) 0.94
Conceptualizing a tool to optimize therapy based on dynamic heterogeneity. Phys Biol (2012) 0.93
Knockdown of the transforming growth factor-beta type III receptor impairs motility and invasion of metastatic cancer cells. Cancer Res (2008) 0.92
N-acetylglucosaminyltransferase V confers hepatoma cells with resistance to anoikis through EGFR/PAK1 activation. Glycobiology (2013) 0.92
Lactobacillus plantarum CCFM8661 alleviates lead toxicity in mice. Biol Trace Elem Res (2012) 0.92
Premalignant breast neoplasia: a paradigm of interlesional and intralesional molecular heterogeneity and its biological and clinical ramifications. Cancer Prev Res (Phila) (2010) 0.91
Identification of a third Protein 4.1 tumor suppressor, Protein 4.1R, in meningioma pathogenesis. Neurobiol Dis (2003) 0.91
Cross-cultural adaptation and validation of the Brazilian Portuguese version of the short musculoskeletal function assessment questionnaire: the SMFA-BR. J Bone Joint Surg Am (2005) 0.91
Method of x-ray anomalous diffraction for lipid structures. Biophys J (2006) 0.90
Chromogenic in situ hybridization is a reliable method for detecting HER2 gene status in breast cancer: a multicenter study using conventional scoring criteria and the new ASCO/CAP recommendations. Am J Clin Pathol (2009) 0.90
National trends in health care utilization and racial and socioeconomic disparities in pediatric pyogenic arthritis. J Pediatr Orthop (2006) 0.90
Sorafenib suppresses growth and survival of hepatoma cells by accelerating degradation of enhancer of zeste homolog 2. Cancer Sci (2013) 0.88
Protective effects of Lactobacillus plantarum CCFM8610 against acute cadmium toxicity in mice. Appl Environ Microbiol (2012) 0.88
Effect of complete protein 4.1R deficiency on ion transport properties of murine erythrocytes. Am J Physiol Cell Physiol (2006) 0.87
New insights into potential functions for the protein 4.1 superfamily of proteins in kidney epithelium. Front Biosci (2006) 0.87
Coordinate transcriptional and translational repression of p53 by TGF-β1 impairs the stress response. Mol Cell (2013) 0.87
Evidence for a protective role of the Gardos channel against hemolysis in murine spherocytosis. Blood (2005) 0.87
Charge density and molecular weight of polyphosphoramidate gene carrier are key parameters influencing its DNA compaction ability and transfection efficiency. Biomacromolecules (2010) 0.86
Unprecedented opportunities and promise for cancer prevention research. Cancer Prev Res (Phila) (2010) 0.86
Effect of a novel proteoglycan PTP1B inhibitor from Ganoderma lucidum on the amelioration of hyperglycaemia and dyslipidaemia in db/db mice. Br J Nutr (2012) 0.86
Increased autophagy accelerates colchicine-induced muscle toxicity. Autophagy (2013) 0.85
Cutting edge: Smad2 and Smad4 regulate TGF-β-mediated Il9 gene expression via EZH2 displacement. J Immunol (2013) 0.85
Tumor miR-125b predicts recurrence and survival of patients with clear-cell renal cell carcinoma after surgical resection. Cancer Sci (2014) 0.83
A protein tyrosine phosphatase 1B activity inhibitor from the fruiting bodies of Ganoderma lucidum (Fr.) Karst and its hypoglycemic potency on streptozotocin-induced type 2 diabetic mice. J Agric Food Chem (2011) 0.83
Directionally-controlled periodic collimated beams of surface plasmon polaritons on metal film in Ag nanowire/Al2O3/Ag film composite structure. Nano Lett (2014) 0.83
Direct interrogation of DNA content distribution in nanoparticles by a novel microfluidics-based single-particle analysis. Nano Lett (2014) 0.83
Role of the phenylalanine-hydroxylating system in aromatic substance degradation and lipid metabolism in the oleaginous fungus Mortierella alpina. Appl Environ Microbiol (2013) 0.82
Modulation of peanut-induced allergic immune responses by oral lactic acid bacteria-based vaccines in mice. Appl Microbiol Biotechnol (2014) 0.82
Microencapsulation of Bifidobacterium bifidum F-35 in whey protein-based microcapsules by transglutaminase-induced gelation. J Food Sci (2012) 0.82
Characterization of cytoskeletal protein 4.1R interaction with NHE1 (Na(+)/H(+) exchanger isoform 1). Biochem J (2012) 0.82
LC3 and p62 as diagnostic markers of drug-induced autophagic vacuolar cardiomyopathy: a study of 3 cases. Am J Surg Pathol (2013) 0.81
Identification of the thymidylate synthase within the genome of white spot syndrome virus. J Gen Virol (2004) 0.81
Erythropoietin receptor expression and its relationship with trastuzumab response and resistance in HER2-positive breast cancer cells. Breast Cancer Res Treat (2012) 0.80
Protein profiling of active cysteine cathepsins in living cells using an activity-based probe containing a cell-penetrating peptide. J Proteome Res (2012) 0.80
Selection of single chain fragment variables with direct coating of aflatoxin B1 to enzyme-linked immunosorbent assay plates. J Agric Food Chem (2009) 0.80
Effects of cryoprotectants on viability of Lactobacillus reuteri CICC6226. Appl Microbiol Biotechnol (2011) 0.80
Similarities and differences in the structure and function of 4.1G and 4.1R135, two protein 4.1 paralogues expressed in erythroid cells. Biochem J (2010) 0.80
Reflections on miR-ing effects in metastasis. Cancer Cell (2009) 0.78
Luminal cells GATA have it. Nat Cell Biol (2007) 0.78
Chitosan ameliorates the severity of steatohepatitis induced by high fat diet in rats. Scand J Gastroenterol (2008) 0.78
Biochemical characterization of the tetrahydrobiopterin synthesis pathway in the oleaginous fungus Mortierella alpina. Microbiology (2011) 0.78