Published in Dev Cell on April 14, 2014
Implications of the Hybrid Epithelial/Mesenchymal Phenotype in Metastasis. Front Oncol (2015) 1.15
Tumor Budding: The Name is EMT. Partial EMT. J Clin Med (2016) 1.00
Stability of the hybrid epithelial/mesenchymal phenotype. Oncotarget (2016) 0.99
OVOL guides the epithelial-hybrid-mesenchymal transition. Oncotarget (2015) 0.93
Quantification of regenerative potential in primary human mammary epithelial cells. Development (2015) 0.93
A Grainyhead-Like 2/Ovo-Like 2 Pathway Regulates Renal Epithelial Barrier Function and Lumen Expansion. J Am Soc Nephrol (2015) 0.90
Coupling the modules of EMT and stemness: A tunable 'stemness window' model. Oncotarget (2015) 0.86
An Ovol2-Zeb1 Mutual Inhibitory Circuit Governs Bidirectional and Multi-step Transition between Epithelial and Mesenchymal States. PLoS Comput Biol (2015) 0.86
Mechanisms of TGFβ-Induced Epithelial-Mesenchymal Transition. J Clin Med (2016) 0.82
Reinforcing targeted therapeutics with phenotypic stability factors. Cell Cycle (2014) 0.81
OVO-like 1 regulates progenitor cell fate in human trophoblast development. Proc Natl Acad Sci U S A (2015) 0.80
A pooled shRNA screen for regulators of primary mammary stem and progenitor cells identifies roles for Asap1 and Prox1. BMC Cancer (2015) 0.79
Ovol proteins: guardians against EMT during epithelial differentiation. Dev Cell (2014) 0.79
Identification of Potentially Pathogenic Variants in the Posterior Polymorphous Corneal Dystrophy 1 Locus. PLoS One (2016) 0.79
Heterotypic control of basement membrane dynamics during branching morphogenesis. Dev Biol (2014) 0.77
Inflammatory breast cancer: a model for investigating cluster-based dissemination. NPJ Breast Cancer (2017) 0.76
Expression of Ovol2 is related to epithelial characteristics and shows a favorable clinical outcome in hepatocellular carcinoma. Onco Targets Ther (2016) 0.76
Grainyhead-like 2 inhibits the coactivator p300, suppressing tubulogenesis and the epithelial-mesenchymal transition. Mol Biol Cell (2016) 0.76
Suppression of the grainyhead transcription factor 2 gene (GRHL2) inhibits the proliferation, migration, invasion and mediates cell cycle arrest of ovarian cancer cells. Cell Cycle (2017) 0.75
Investigating the Molecular Basis of PPCD3: Characterization of ZEB1 Regulation of COL4A3 Expression. Invest Ophthalmol Vis Sci (2016) 0.75
Cell Fate Decisions During Breast Cancer Development. J Dev Biol (2016) 0.75
Revisiting epithelial-mesenchymal transition in cancer metastasis: the connection between epithelial plasticity and stemness. Mol Oncol (2017) 0.75
Phenotypic Plasticity and Cell Fate Decisions in Cancer: Insights from Dynamical Systems Theory. Cancers (Basel) (2017) 0.75
Cancer Is to Embryology as Mutation Is to Genetics: Hypothesis of the Cancer as Embryological Phenomenon. ScientificWorldJournal (2017) 0.75
Epithelial-mesenchymal plasticity: How have quantitative mathematical models helped improve our understanding? Mol Oncol (2017) 0.75
EMT: Present and future in clinical oncology. Mol Oncol (2017) 0.75
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci U S A (2005) 167.46
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell (2006) 120.51
The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell (2008) 46.08
Epithelial-mesenchymal transitions in development and disease. Cell (2009) 39.17
The basics of epithelial-mesenchymal transition. J Clin Invest (2009) 32.82
Generation of a functional mammary gland from a single stem cell. Nature (2006) 18.30
Purification and unique properties of mammary epithelial stem cells. Nature (2006) 15.98
Tumor metastasis: molecular insights and evolving paradigms. Cell (2011) 10.34
A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts. Cell Stem Cell (2010) 7.94
TGF-beta-induced epithelial to mesenchymal transition. Cell Res (2009) 7.88
Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice. Cell (1988) 6.48
Distinct stem cells contribute to mammary gland development and maintenance. Nature (2011) 6.32
In vivo antitumor activity of MEK and phosphatidylinositol 3-kinase inhibitors in basal-like breast cancer models. Clin Cancer Res (2009) 4.81
Slug and Sox9 cooperatively determine the mammary stem cell state. Cell (2012) 4.77
Collective epithelial migration and cell rearrangements drive mammary branching morphogenesis. Dev Cell (2008) 4.18
The ZEB/miR-200 feedback loop--a motor of cellular plasticity in development and cancer? EMBO Rep (2010) 4.05
Poised chromatin at the ZEB1 promoter enables breast cancer cell plasticity and enhances tumorigenicity. Cell (2013) 3.61
In situ identification of bipotent stem cells in the mammary gland. Nature (2014) 2.71
Mammary development in the embryo and adult: a journey of morphogenesis and commitment. Development (2008) 2.69
Elf5 inhibits the epithelial-mesenchymal transition in mammary gland development and breast cancer metastasis by transcriptionally repressing Snail2. Nat Cell Biol (2012) 2.46
Amphiregulin is an essential mediator of estrogen receptor alpha function in mammary gland development. Proc Natl Acad Sci U S A (2007) 2.32
Lentiviral transduction of mammary stem cells for analysis of gene function during development and cancer. Cell Stem Cell (2008) 2.24
ECM microenvironment regulates collective migration and local dissemination in normal and malignant mammary epithelium. Proc Natl Acad Sci U S A (2012) 2.20
Candidate regulators of mammary branching morphogenesis identified by genome-wide transcript analysis. Dev Dyn (2006) 2.03
GATA3 suppresses metastasis and modulates the tumour microenvironment by regulating microRNA-29b expression. Nat Cell Biol (2013) 2.03
The MAPK(ERK-1,2) pathway integrates distinct and antagonistic signals from TGFalpha and FGF7 in morphogenesis of mouse mammary epithelium. Dev Biol (2007) 1.98
The ovo gene required for cuticle formation and oogenesis in flies is involved in hair formation and spermatogenesis in mice. Genes Dev (1998) 1.78
TGF-beta biology in mammary development and breast cancer. Cold Spring Harb Perspect Biol (2011) 1.75
Pygo2 expands mammary progenitor cells by facilitating histone H3 K4 methylation. J Cell Biol (2009) 1.65
Lumen formation during mammary epithelial morphogenesis: insights from in vitro and in vivo models. Cell Cycle (2007) 1.62
Suppression of the epithelial-mesenchymal transition by Grainyhead-like-2. Cancer Res (2012) 1.50
Ovol1 regulates the growth arrest of embryonic epidermal progenitor cells and represses c-myc transcription. J Cell Biol (2006) 1.42
Transcription factors OVOL1 and OVOL2 induce the mesenchymal to epithelial transition in human cancer. PLoS One (2013) 1.32
Mammary collective cell migration involves transient loss of epithelial features and individual cell migration within the epithelium. J Cell Sci (2012) 1.32
Rare somatic cells from human breast tissue exhibit extensive lineage plasticity. Proc Natl Acad Sci U S A (2013) 1.31
Cell polarity in motion: redefining mammary tissue organization through EMT and cell polarity transitions. J Mammary Gland Biol Neoplasia (2010) 1.17
Genome-wide profiles of CtBP link metabolism with genome stability and epithelial reprogramming in breast cancer. Nat Commun (2013) 1.13
Ovol1 regulates meiotic pachytene progression during spermatogenesis by repressing Id2 expression. Development (2005) 1.12
EMT in developmental morphogenesis. Cancer Lett (2013) 1.08
Ovol2 suppresses cell cycling and terminal differentiation of keratinocytes by directly repressing c-Myc and Notch1. J Biol Chem (2009) 1.05
Transcriptional mechanisms link epithelial plasticity to adhesion and differentiation of epidermal progenitor cells. Dev Cell (2014) 1.04
The zinc finger transcription factor Ovol2 acts downstream of the bone morphogenetic protein pathway to regulate the cell fate decision between neuroectoderm and mesendoderm. J Biol Chem (2013) 1.03
Chromatin effector Pygo2 mediates Wnt-notch crosstalk to suppress luminal/alveolar potential of mammary stem and basal cells. Cell Stem Cell (2013) 1.00
Ovol2/Movo, a homologue of Drosophila ovo, is required for angiogenesis, heart formation and placental development in mice. Genes Cells (2007) 0.99
Ovol2, a mammalian homolog of Drosophila ovo: gene structure, chromosomal mapping, and aberrant expression in blind-sterile mice. Genomics (2002) 0.98
Slug controls stem/progenitor cell growth dynamics during mammary gland morphogenesis. PLoS One (2012) 0.98
Changes in adhesive properties of epithelial cells during early morphogenesis of the mammary gland. Dev Growth Differ (2001) 0.97
Snail/Gfi-1 (SNAG) family zinc finger proteins in transcription regulation, chromatin dynamics, cell signaling, development, and disease. Cytokine Growth Factor Rev (2012) 0.94
To grow mouse mammary epithelial cells in culture. J Cell Biol (1984) 0.92
Ovol1 represses its own transcription by competing with transcription activator c-Myb and by recruiting histone deacetylase activity. Nucleic Acids Res (2007) 0.90
Ovo1 links Wnt signaling with N-cadherin localization during neural crest migration. Development (2010) 0.88
Chromatin effector Pygo2 regulates mammary tumor initiation and heterogeneity in MMTV-Wnt1 mice. Oncogene (2013) 0.87
A noncoding point mutation of Zeb1 causes multiple developmental malformations and obesity in Twirler mice. PLoS Genet (2011) 0.87
Gene expression in murine mammary epithelial stem cell-like cells shows similarities to human breast cancer gene expression. Breast Cancer Res (2009) 0.85
Proteomic analysis of mouse mammary terminal end buds identifies axonal growth cone proteins. Proteomics (2004) 0.78