PubRank

Augustine Kong

Author PubWeight™ 673.96‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Finding the missing heritability of complex diseases. Nature 2009 67.95
2 Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet 2008 35.06
3 Genetics of gene expression and its effect on disease. Nature 2008 21.35
4 Large recurrent microdeletions associated with schizophrenia. Nature 2008 20.25
5 Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24. Nat Genet 2007 19.18
6 Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nat Genet 2006 19.03
7 A common variant on chromosome 9p21 affects the risk of myocardial infarction. Science 2007 18.96
8 New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet 2010 17.89
9 Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet 2010 16.96
10 Missing heritability and strategies for finding the underlying causes of complex disease. Nat Rev Genet 2010 14.81
11 A common inversion under selection in Europeans. Nat Genet 2005 13.66
12 A common variant associated with prostate cancer in European and African populations. Nat Genet 2006 13.47
13 A variant in CDKAL1 influences insulin response and risk of type 2 diabetes. Nat Genet 2007 13.28
14 Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet 2011 13.25
15 Many sequence variants affecting diversity of adult human height. Nat Genet 2008 12.80
16 Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes. Nat Genet 2007 12.65
17 Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. Nat Genet 2008 12.43
18 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet 2012 11.09
19 Variants in MTNR1B influence fasting glucose levels. Nat Genet 2008 10.85
20 Common variants on chromosomes 2q35 and 16q12 confer susceptibility to estrogen receptor-positive breast cancer. Nat Genet 2007 10.81
21 Common variants conferring risk of schizophrenia. Nature 2009 10.37
22 Variant of TREM2 associated with the risk of Alzheimer's disease. N Engl J Med 2012 10.16
23 A mutation in APP protects against Alzheimer's disease and age-related cognitive decline. Nature 2012 8.10
24 Variants conferring risk of atrial fibrillation on chromosome 4q25. Nature 2007 8.03
25 Common variants on chromosome 5p12 confer susceptibility to estrogen receptor-positive breast cancer. Nat Genet 2008 7.65
26 Common sequence variants in the LOXL1 gene confer susceptibility to exfoliation glaucoma. Science 2007 7.55
27 Neuregulin 1 and susceptibility to schizophrenia. Am J Hum Genet 2002 7.40
28 The gene encoding phosphodiesterase 4D confers risk of ischemic stroke. Nat Genet 2003 7.37
29 Mapping cis- and trans-regulatory effects across multiple tissues in twins. Nat Genet 2012 6.97
30 Sequence variants at the TERT-CLPTM1L locus associate with many cancer types. Nat Genet 2009 6.91
31 Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction. Nat Genet 2009 6.83
32 The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm. Nat Genet 2008 6.72
33 Sequence variant on 8q24 confers susceptibility to urinary bladder cancer. Nat Genet 2008 6.69
34 Multiple genetic loci for bone mineral density and fractures. N Engl J Med 2008 6.35
35 Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer. Nat Genet 2008 6.10
36 Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution. Nat Genet 2007 5.88
37 Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet 2009 5.81
38 A genetic risk factor for periodic limb movements in sleep. N Engl J Med 2007 5.77
39 Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies. Nat Genet 2009 5.32
40 The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke. Nat Genet 2004 5.31
41 Genome-wide association and replication studies identify four variants associated with prostate cancer susceptibility. Nat Genet 2009 5.06
42 Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nat Genet 2012 4.73
43 A variant of the gene encoding leukotriene A4 hydrolase confers ethnicity-specific risk of myocardial infarction. Nat Genet 2005 4.45
44 New common variants affecting susceptibility to basal cell carcinoma. Nat Genet 2009 4.15
45 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet 2014 4.13
46 A sequence variant in ZFHX3 on 16q22 associates with atrial fibrillation and ischemic stroke. Nat Genet 2009 4.11
47 Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways. Diabetes 2010 4.07
48 A rare variant in MYH6 is associated with high risk of sick sinus syndrome. Nat Genet 2011 3.94
49 ASIP and TYR pigmentation variants associate with cutaneous melanoma and basal cell carcinoma. Nat Genet 2008 3.90
50 Risk variants for atrial fibrillation on chromosome 4q25 associate with ischemic stroke. Ann Neurol 2008 3.75
51 Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in European populations. Nat Genet 2009 3.46
52 New sequence variants associated with bone mineral density. Nat Genet 2008 3.43
53 Several common variants modulate heart rate, PR interval and QRS duration. Nat Genet 2010 3.34
54 Two newly identified genetic determinants of pigmentation in Europeans. Nat Genet 2008 3.31
55 Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet 2012 3.21
56 Identification of an imprinted master trans regulator at the KLF14 locus related to multiple metabolic phenotypes. Nat Genet 2011 3.20
57 Mutations in BRIP1 confer high risk of ovarian cancer. Nat Genet 2011 3.06
58 Allegro version 2. Nat Genet 2005 2.98
59 Genetic correction of PSA values using sequence variants associated with PSA levels. Sci Transl Med 2010 2.83
60 Collaborative meta-analysis: associations of 150 candidate genes with osteoporosis and osteoporotic fracture. Ann Intern Med 2009 2.80
61 Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma. Nat Genet 2010 2.75
62 Cancer as a complex phenotype: pattern of cancer distribution within and beyond the nuclear family. PLoS Med 2004 2.67
63 Association of neuregulin 1 with schizophrenia confirmed in a Scottish population. Am J Hum Genet 2002 2.64
64 Genome-wide association study identifies sequence variants on 6q21 associated with age at menarche. Nat Genet 2009 2.58
65 A sequence variant at 4p16.3 confers susceptibility to urinary bladder cancer. Nat Genet 2010 2.56
66 Nonsense mutation in the LGR4 gene is associated with several human diseases and other traits. Nature 2013 2.55
67 Single-tissue and cross-tissue heritability of gene expression via identity-by-descent in related or unrelated individuals. PLoS Genet 2011 2.53
68 Familial risk of lung carcinoma in the Icelandic population. JAMA 2004 2.50
69 Identification of low-frequency variants associated with gout and serum uric acid levels. Nat Genet 2011 2.48
70 A germline variant in the TP53 polyadenylation signal confers cancer susceptibility. Nat Genet 2011 2.43
71 A direct characterization of human mutation based on microsatellites. Nat Genet 2012 2.38
72 The association of a SNP upstream of INSIG2 with body mass index is reproduced in several but not all cohorts. PLoS Genet 2007 2.35
73 Variant in the sequence of the LINGO1 gene confers risk of essential tremor. Nat Genet 2009 2.29
74 A study based on whole-genome sequencing yields a rare variant at 8q24 associated with prostate cancer. Nat Genet 2012 2.29
75 Common variants at VRK2 and TCF4 conferring risk of schizophrenia. Hum Mol Genet 2011 2.21
76 CFH Y402H confers similar risk of soft drusen and both forms of advanced AMD. PLoS Med 2005 2.01
77 Effects of a 5-lipoxygenase-activating protein inhibitor on biomarkers associated with risk of myocardial infarction: a randomized trial. JAMA 2005 1.94
78 A susceptibility gene for late-onset idiopathic Parkinson's disease. Ann Neurol 2002 1.92
79 The impact of divergence time on the nature of population structure: an example from Iceland. PLoS Genet 2009 1.89
80 Male-pattern baldness susceptibility locus at 20p11. Nat Genet 2008 1.87
81 Common variants on 1p36 and 1q42 are associated with cutaneous basal cell carcinoma but not with melanoma or pigmentation traits. Nat Genet 2008 1.84
82 Discovery of common variants associated with low TSH levels and thyroid cancer risk. Nat Genet 2012 1.81
83 Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm. Nat Genet 2010 1.79
84 A sequence variant on 17q21 is associated with age at onset and severity of asthma. Eur J Hum Genet 2010 1.74
85 Sequence variants in the CLDN14 gene associate with kidney stones and bone mineral density. Nat Genet 2009 1.73
86 A novel TEAD1 mutation is the causative allele in Sveinsson's chorioretinal atrophy (helicoid peripapillary chorioretinal degeneration). Hum Mol Genet 2004 1.72
87 A genome-wide association search for type 2 diabetes genes in African Americans. PLoS One 2012 1.72
88 Localization of a susceptibility gene for common forms of stroke to 5q12. Am J Hum Genet 2002 1.67
89 Linkage of osteoporosis to chromosome 20p12 and association to BMP2. PLoS Biol 2003 1.64
90 Localization of a susceptibility gene for type 2 diabetes to chromosome 5q34-q35.2. Am J Hum Genet 2003 1.62
91 European genome-wide association study identifies SLC14A1 as a new urinary bladder cancer susceptibility gene. Hum Mol Genet 2011 1.58
92 Association of variants at UMOD with chronic kidney disease and kidney stones-role of age and comorbid diseases. PLoS Genet 2010 1.57
93 Genomewide scan for hand osteoarthritis: a novel mutation in matrilin-3. Am J Hum Genet 2003 1.56
94 The BARD1 Cys557Ser variant and breast cancer risk in Iceland. PLoS Med 2006 1.53
95 A susceptibility gene for psoriatic arthritis maps to chromosome 16q: evidence for imprinting. Am J Hum Genet 2002 1.45
96 Anxiety with panic disorder linked to chromosome 9q in Iceland. Am J Hum Genet 2003 1.44
97 A major susceptibility gene for asthma maps to chromosome 14q24. Am J Hum Genet 2002 1.36
98 European bone mineral density loci are also associated with BMD in East-Asian populations. PLoS One 2010 1.29
99 A rare nonsynonymous sequence variant in C3 is associated with high risk of age-related macular degeneration. Nat Genet 2013 1.23
100 Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets. PLoS Genet 2013 1.04
101 Sequence variants at CYP1A1-CYP1A2 and AHR associate with coffee consumption. Hum Mol Genet 2011 1.03
102 Linkage of essential hypertension to chromosome 18q. Hypertension 2002 1.03
103 Support for involvement of the AHI1 locus in schizophrenia. Eur J Hum Genet 2007 1.03
104 Localization of a gene for peripheral arterial occlusive disease to chromosome 1p31. Am J Hum Genet 2002 1.02
105 Localization of a gene for migraine without aura to chromosome 4q21. Am J Hum Genet 2003 0.99
106 A common variant at 8q24.21 is associated with renal cell cancer. Nat Commun 2013 0.96
107 Genome-wide significant association between a sequence variant at 15q15.2 and lung cancer risk. Cancer Res 2011 0.92
108 Germline sequence variants in TGM3 and RGS22 confer risk of basal cell carcinoma. Hum Mol Genet 2014 0.90
109 Measuring the relative information in allele-sharing linkage studies. Biometrics 2004 0.87
110 Familial predisposition and cosegregation analysis of adult obstructive sleep apnea and the sudden infant death syndrome. Am J Respir Crit Care Med 2002 0.84
111 Comment on the phosphodiesterase 4D replication study by Bevan et al. Stroke 2005 0.75
112 Corrigendum: Whole-genome sequencing identifies rare genotypes in COMP and CHADL associated with high risk of hip osteoarthritis. Nat Genet 2017 0.75