Published in Inflamm Allergy Drug Targets on October 01, 2013
Molecular mechanism and therapeutic modulation of high mobility group box 1 release and action: an updated review. Expert Rev Clin Immunol (2014) 0.94
Novel Mechanisms of Herbal Therapies for Inhibiting HMGB1 Secretion or Action. Evid Based Complement Alternat Med (2015) 0.84
EGCG induces G-CSF expression and neutrophilia in experimental sepsis. Immunol Res (2015) 0.75
An ongoing search for potential targets and therapies for lethal sepsis. Mil Med Res (2015) 0.75
Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med (2001) 46.58
EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers. Nat Struct Mol Biol (2008) 5.32
Green tea composition, consumption, and polyphenol chemistry. Prev Med (1992) 3.46
EGCG remodels mature alpha-synuclein and amyloid-beta fibrils and reduces cellular toxicity. Proc Natl Acad Sci U S A (2010) 2.48
A receptor for green tea polyphenol EGCG. Nat Struct Mol Biol (2004) 2.46
Antioxidant activity of tea polyphenols in vivo: evidence from animal studies. J Nutr (2003) 2.17
Antiviral effect of catechins in green tea on influenza virus. Antiviral Res (2005) 2.10
Bactericidal catechins damage the lipid bilayer. Biochim Biophys Acta (1993) 2.06
Mechanism of synergy between epigallocatechin gallate and beta-lactams against methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother (2001) 2.05
Modulation of beta-lactam resistance in Staphylococcus aureus by catechins and gallates. Int J Antimicrob Agents (2004) 1.63
A review of the health effects of green tea catechins in in vivo animal models. J Nutr (2004) 1.54
Inhibition of the infectivity of influenza virus by tea polyphenols. Antiviral Res (1993) 1.51
EGCG stimulates autophagy and reduces cytoplasmic HMGB1 levels in endotoxin-stimulated macrophages. Biochem Pharmacol (2011) 1.41
Role of hydrogen peroxide in bactericidal action of catechin. Biol Pharm Bull (2004) 1.35
Anti-infective properties of epigallocatechin-3-gallate (EGCG), a component of green tea. Br J Pharmacol (2013) 1.33
Mechanisms of quenching of Alexa fluorophores by natural amino acids. J Am Chem Soc (2010) 1.31
A major ingredient of green tea rescues mice from lethal sepsis partly by inhibiting HMGB1. PLoS One (2007) 1.30
The role of quercetin, flavonols and flavones in modulating inflammatory cell function. Inflamm Allergy Drug Targets (2010) 1.30
A hepatic protein, fetuin-A, occupies a protective role in lethal systemic inflammation. PLoS One (2011) 1.25
Inhibition of penicillinase by epigallocatechin gallate resulting in restoration of antibacterial activity of penicillin against penicillinase-producing Staphylococcus aureus. Antimicrob Agents Chemother (2002) 1.15
Interaction of tea catechin (-)-epigallocatechin gallate with lipid bilayers. Biophys J (2009) 1.14
Epigallocatechin-gallate enhances the activity of tetracycline in staphylococci by inhibiting its efflux from bacterial cells. Antimicrob Agents Chemother (2004) 1.10
Epigallocatechin gallate synergy with ampicillin/sulbactam against 28 clinical isolates of methicillin-resistant Staphylococcus aureus. J Antimicrob Chemother (2001) 1.09
Tea consumption and cardiovascular disease: effects on endothelial function. J Nutr (2003) 1.09
Bioassay-guided purification and identification of antimicrobial components in Chinese green tea extract. J Chromatogr A (2006) 1.08
Antimicrobial activity of the green tea polyphenol (-)-epigallocatechin-3-gallate (EGCG) against clinical isolates of Stenotrophomonas maltophilia. Int J Antimicrob Agents (2010) 1.08
Green tea catechins inhibit bacterial DNA gyrase by interaction with its ATP binding site. J Med Chem (2007) 1.05
Different susceptibilities of Staphylococcus and Gram-negative rods to epigallocatechin gallate. J Infect Chemother (2004) 1.05
Epigallocatechin gallate inactivates clinical isolates of herpes simplex virus. Antimicrob Agents Chemother (2008) 1.04
Carbenoxolone blocks endotoxin-induced protein kinase R (PKR) activation and high mobility group box 1 (HMGB1) release. Mol Med (2013) 0.92
Relationship between antibacterial activity of (+)-catechin derivatives and their interaction with a model membrane. J Agric Food Chem (2004) 0.92
Inhibitory effects of green tea catechins on protein tyrosine phosphatase in Prevotella intermedia. Oral Microbiol Immunol (2003) 0.91
(-)Epigallocatechin-3-gallate inhibits gelatinase activity of some bacterial isolates from ocular infection, and limits their invasion through gelatine. Biochim Biophys Acta (2003) 0.90
Epigallocatechin gallate inhibits intracellular survival of Listeria monocytogenes in macrophages. Biochem Biophys Res Commun (2007) 0.87
Legionella pneumophila replication in macrophages inhibited by selective immunomodulatory effects on cytokine formation by epigallocatechin gallate, a major form of tea catechins. Infect Immun (2001) 0.85
Antifungal susceptibility of epigallocatechin 3-O-gallate (EGCg) on clinical isolates of pathogenic yeasts. Biochem Biophys Res Commun (2006) 0.84
Economics of antibiotic resistance. Expert Rev Anti Infect Ther (2008) 0.84
Increase in sepsis due to multi-resistant enteric gram-negative bacilli in Papua New Guinea. Lancet (1999) 0.84
Synergistic anti-bacterial and proteomic effects of epigallocatechin gallate on clinical isolates of imipenem-resistant Klebsiella pneumoniae. Phytomedicine (2011) 0.82
Use of animal model of sepsis to evaluate novel herbal therapies. J Vis Exp (2012) 0.81
Novel bactericidal surface: Catechin-loaded surface-erodible polymer prevents biofilm formation. J Biomed Mater Res A (2005) 0.81
Mechanisms for epigallocatechin gallate induced inhibition of drug metabolizing enzymes in rat liver microsomes. Toxicol Lett (2012) 0.81
Green tea polyphenol epigallocatechin-3-gallate (EGCG) induced intermolecular cross-linking of membrane proteins. Arch Biochem Biophys (2011) 0.80
Interaction of tea catechins with lipid bilayers investigated by a quartz-crystal microbalance analysis. Biosci Biotechnol Biochem (2008) 0.80
Fluorescence of Alexa fluor dye tracks protein folding. PLoS One (2012) 0.79
Antibiotics in the intensive care unit: focus on agents for resistant pathogens. Emerg Med Clin North Am (2008) 0.78
A proprietary topical preparation containing EGCG-stearate and glycerin with inhibitory effects on herpes simplex virus: case study. Inflamm Allergy Drug Targets (2012) 0.78
Protective effects of green tea catechins on alveolar macrophages against bacterial infections. Biofactors (2004) 0.78
Interaction of (-)-epigallocatechin gallate with lysozyme-conjugated silver nanoparticles. Appl Spectrosc (2012) 0.76
Limitations of inhibitory activities of polyphenols on furin-mediated substrate processing. Curr Med Chem (2012) 0.76
Model-based analysis of ChIP-Seq (MACS). Genome Biol (2008) 51.63
A draft sequence of the rice genome (Oryza sativa L. ssp. indica). Science (2002) 42.78
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Genome-wide analysis of estrogen receptor binding sites. Nat Genet (2006) 18.63
Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1. Cell (2005) 14.32
FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription. Cell (2008) 14.18
Model-based analysis of tiling-arrays for ChIP-chip. Proc Natl Acad Sci U S A (2006) 13.68
Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation. Nature (2002) 12.09
High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal. Nat Rev Immunol (2005) 11.57
Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases. Cancer Cell (2011) 11.44
Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex. Nature (2002) 10.96
Genome-wide association studies of 14 agronomic traits in rice landraces. Nat Genet (2010) 8.75
The role of microRNA genes in papillary thyroid carcinoma. Proc Natl Acad Sci U S A (2005) 8.60
Extensive promoter-centered chromatin interactions provide a topological basis for transcription regulation. Cell (2012) 8.41
Model-based analysis of two-color arrays (MA2C). Genome Biol (2007) 7.28
Reversing established sepsis with antagonists of endogenous high-mobility group box 1. Proc Natl Acad Sci U S A (2003) 7.14
Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer. Cell (2009) 7.09
Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications. Nat Biotechnol (2010) 7.00
The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion. J Exp Med (2005) 6.86
PlasmoDB: a functional genomic database for malaria parasites. Nucleic Acids Res (2008) 6.73
iPS cells produce viable mice through tetraploid complementation. Nature (2009) 6.51
Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis. Nat Med (2004) 6.38
HMGB1 is a therapeutic target for sterile inflammation and infection. Annu Rev Immunol (2011) 6.23
Origin and diversity of novel avian influenza A H7N9 viruses causing human infection: phylogenetic, structural, and coalescent analyses. Lancet (2013) 6.10
A hierarchical network of transcription factors governs androgen receptor-dependent prostate cancer growth. Mol Cell (2007) 5.99
Acetylcholine-synthesizing T cells relay neural signals in a vagus nerve circuit. Science (2011) 5.87
BSMAP: whole genome bisulfite sequence MAPping program. BMC Bioinformatics (2009) 5.67
Sepsis definitions: time for change. Lancet (2013) 5.63
Evidence that ternary complex (eIF2-GTP-tRNA(i)(Met))-deficient preinitiation complexes are core constituents of mammalian stress granules. Mol Biol Cell (2002) 5.20
Bone marrow edema and its relation to progression of knee osteoarthritis. Ann Intern Med (2003) 4.98
Cardiovascular risk and events in 17 low-, middle-, and high-income countries. N Engl J Med (2014) 4.88
Association of urinary sodium and potassium excretion with blood pressure. N Engl J Med (2014) 4.86
Dnmt3a is essential for hematopoietic stem cell differentiation. Nat Genet (2011) 4.85
Endogenous HMGB1 regulates autophagy. J Cell Biol (2010) 4.71
A G protein-coupled receptor is a plasma membrane receptor for the plant hormone abscisic acid. Science (2007) 4.61
HMGB1 signals through toll-like receptor (TLR) 4 and TLR2. Shock (2006) 4.53
A gene expression network model of type 2 diabetes links cell cycle regulation in islets with diabetes susceptibility. Genome Res (2008) 4.33
RSeQC: quality control of RNA-seq experiments. Bioinformatics (2012) 4.31
Productivity is a poor predictor of plant species richness. Science (2011) 4.21
A novel influenza A (H1N1) vaccine in various age groups. N Engl J Med (2009) 4.20
Systematic evaluation of variability in ChIP-chip experiments using predefined DNA targets. Genome Res (2008) 4.08
A broadly implementable research course in phage discovery and genomics for first-year undergraduate students. MBio (2014) 3.93
Association between adverse clinical outcome in human disease caused by novel influenza A H7N9 virus and sustained viral shedding and emergence of antiviral resistance. Lancet (2013) 3.83
A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release. Proc Natl Acad Sci U S A (2010) 3.80
TriTrypDB: a functional genomic resource for the Trypanosomatidae. Nucleic Acids Res (2009) 3.79
Future research directions in acute lung injury: summary of a National Heart, Lung, and Blood Institute working group. Am J Respir Crit Care Med (2003) 3.75
Receptor-like cytoplasmic kinases integrate signaling from multiple plant immune receptors and are targeted by a Pseudomonas syringae effector. Cell Host Microbe (2010) 3.73
Ethyl pyruvate prevents lethality in mice with established lethal sepsis and systemic inflammation. Proc Natl Acad Sci U S A (2002) 3.68
Splenectomy inactivates the cholinergic antiinflammatory pathway during lethal endotoxemia and polymicrobial sepsis. J Exp Med (2006) 3.66
Simultaneous generation and germline transmission of multiple gene mutations in rat using CRISPR-Cas systems. Nat Biotechnol (2013) 3.65
Selective alpha7-nicotinic acetylcholine receptor agonist GTS-21 improves survival in murine endotoxemia and severe sepsis. Crit Care Med (2007) 3.63
Sexual cycle of Cryptococcus neoformans var. grubii and virulence of congenic a and alpha isolates. Infect Immun (2003) 3.61
Persistent elevation of high mobility group box-1 protein (HMGB1) in patients with severe sepsis and septic shock. Crit Care Med (2005) 3.58
A PCR-based strategy to generate integrative targeting alleles with large regions of homology. Microbiology (2002) 3.58
Meta-analysis of traditional Chinese patent medicine for ischemic stroke. Stroke (2007) 3.46
Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in European populations. Nat Genet (2009) 3.46
Theoretical, empirical and practical approaches to resolving the unmet information needs of clinical information system users. Proc AMIA Symp (2002) 3.45
Metabolic syndrome in childhood predicts adult metabolic syndrome and type 2 diabetes mellitus 25 to 30 years later. J Pediatr (2007) 3.45
Circulating high-mobility group box 1 (HMGB1) concentrations are elevated in both uncomplicated pneumonia and pneumonia with severe sepsis. Crit Care Med (2007) 3.27
The Felodipine Event Reduction (FEVER) Study: a randomized long-term placebo-controlled trial in Chinese hypertensive patients. J Hypertens (2005) 3.27
Role of HMGB1 in apoptosis-mediated sepsis lethality. J Exp Med (2006) 3.26
Effectiveness of first eight methadone maintenance treatment clinics in China. AIDS (2007) 3.18
CEAS: cis-regulatory element annotation system. Nucleic Acids Res (2006) 3.15
Novel role of PKR in inflammasome activation and HMGB1 release. Nature (2012) 3.13
A novel role for HMGB1 in TLR9-mediated inflammatory responses to CpG-DNA. Blood (2007) 3.09
The cytokine activity of HMGB1. J Leukoc Biol (2005) 3.02
Cholinergic stimulation blocks endothelial cell activation and leukocyte recruitment during inflammation. J Exp Med (2005) 3.01
Analysis of the human endogenous coregulator complexome. Cell (2011) 2.97
SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation. Nature (2012) 2.96
Integrative analysis of HIF binding and transactivation reveals its role in maintaining histone methylation homeostasis. Proc Natl Acad Sci U S A (2009) 2.95
HMGB1 B box increases the permeability of Caco-2 enterocytic monolayers and impairs intestinal barrier function in mice. Gastroenterology (2002) 2.95
The "cytokine profile": a code for sepsis. Trends Mol Med (2005) 2.89
Mutually exclusive redox forms of HMGB1 promote cell recruitment or proinflammatory cytokine release. J Exp Med (2012) 2.89
CPAT: Coding-Potential Assessment Tool using an alignment-free logistic regression model. Nucleic Acids Res (2013) 2.88
Inflammasome-dependent release of the alarmin HMGB1 in endotoxemia. J Immunol (2010) 2.88
Crystal structure of a stable dimer reveals the molecular basis of serpin polymerization. Nature (2008) 2.88
Right ventricular function in adults with repaired tetralogy of Fallot assessed with cardiovascular magnetic resonance imaging: detrimental role of right ventricular outflow aneurysms or akinesia and adverse right-to-left ventricular interaction. J Am Coll Cardiol (2002) 2.87
Poly[bis[aquaneodymium(III)]-mu2-oxalato-di-mu4-succinato]. Acta Crystallogr C (2007) 2.84
Prolonged diabetes reversal after intraportal xenotransplantation of wild-type porcine islets in immunosuppressed nonhuman primates. Nat Med (2006) 2.83
Pharmacological stimulation of the cholinergic antiinflammatory pathway. J Exp Med (2002) 2.83
Redox modification of cysteine residues regulates the cytokine activity of high mobility group box-1 (HMGB1). Mol Med (2012) 2.79
Function annotation of the rice transcriptome at single-nucleotide resolution by RNA-seq. Genome Res (2010) 2.73
NMDA-mediated activation of the tyrosine phosphatase STEP regulates the duration of ERK signaling. Nat Neurosci (2003) 2.70
The PSA(-/lo) prostate cancer cell population harbors self-renewing long-term tumor-propagating cells that resist castration. Cell Stem Cell (2012) 2.69
A C. elegans model of nicotine-dependent behavior: regulation by TRP-family channels. Cell (2006) 2.68
Scaling up the national methadone maintenance treatment program in China: achievements and challenges. Int J Epidemiol (2010) 2.65
MicroRNA-21 and microRNA-148a contribute to DNA hypomethylation in lupus CD4+ T cells by directly and indirectly targeting DNA methyltransferase 1. J Immunol (2010) 2.63
Genetic networks of liver metabolism revealed by integration of metabolic and transcriptional profiling. PLoS Genet (2008) 2.63