Published in Int J Exp Pathol on April 25, 2014
Biomechanical and biochemical remodeling of stromal extracellular matrix in cancer. Trends Biotechnol (2015) 0.99
Flavonoids Affect Host-Microbiota Crosstalk through TLR Modulation. Antioxidants (Basel) (2014) 0.77
MicroRNAs: genomics, biogenesis, mechanism, and function. Cell (2004) 198.59
MicroRNAs: target recognition and regulatory functions. Cell (2009) 92.17
The functions of animal microRNAs. Nature (2004) 64.85
MicroRNA signatures in human cancers. Nat Rev Cancer (2006) 46.29
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat Cell Biol (2007) 37.10
Identification of tissue-specific microRNAs from mouse. Curr Biol (2002) 34.55
Mammalian microRNAs predominantly act to decrease target mRNA levels. Nature (2010) 22.04
NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc Natl Acad Sci U S A (2006) 21.58
Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP. Cell (2010) 17.87
Requirement of bic/microRNA-155 for normal immune function. Science (2007) 16.24
Dicer is essential for mouse development. Nat Genet (2003) 15.87
MicroRNA expression in zebrafish embryonic development. Science (2005) 15.52
Endogenous human microRNAs that suppress breast cancer metastasis. Nature (2008) 14.37
HITS-CLIP yields genome-wide insights into brain alternative RNA processing. Nature (2008) 14.17
A coding-independent function of gene and pseudogene mRNAs regulates tumour biology. Nature (2010) 13.82
Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry. Circ Res (2003) 13.22
Regulation of the germinal center response by microRNA-155. Science (2007) 12.25
Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing. Genes Dev (2005) 12.15
MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts. Nature (2008) 10.73
Retracted A pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis. Cell (2009) 10.51
A ceRNA hypothesis: the Rosetta Stone of a hidden RNA language? Cell (2011) 10.50
A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure. Proc Natl Acad Sci U S A (2006) 10.09
Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis. Proc Natl Acad Sci U S A (2008) 9.86
SMAD proteins control DROSHA-mediated microRNA maturation. Nature (2008) 9.67
DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal. Nat Genet (2007) 9.25
Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury. J Biol Chem (2000) 9.07
Shedding microvesicles: artefacts no more. Trends Cell Biol (2009) 8.84
The extracellular matrix: not just pretty fibrils. Science (2009) 8.52
MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins. Nat Cell Biol (2011) 8.21
Modulation of miR-155 and miR-125b levels following lipopolysaccharide/TNF-alpha stimulation and their possible roles in regulating the response to endotoxin shock. J Immunol (2007) 8.05
miRiad roles for the miR-17-92 cluster in development and disease. Cell (2008) 8.02
The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis. Nat Cell Biol (2008) 7.86
Physiological and pathological roles for microRNAs in the immune system. Nat Rev Immunol (2010) 7.75
A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells. Cell (1991) 7.29
Decoding the patterns of self and nonself by the innate immune system. Science (2002) 7.19
MicroRNA control in the immune system: basic principles. Cell (2009) 7.16
Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAs. Cell (2011) 7.02
Exosomes--vesicular carriers for intercellular communication. Curr Opin Cell Biol (2009) 6.96
The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44. Nat Med (2011) 6.85
Defects in mesoderm, neural tube and vascular development in mouse embryos lacking fibronectin. Development (1993) 6.56
The extracellular matrix: a dynamic niche in cancer progression. J Cell Biol (2012) 6.07
An extensive microRNA-mediated network of RNA-RNA interactions regulates established oncogenic pathways in glioblastoma. Cell (2011) 5.75
Inositol phosphatase SHIP1 is a primary target of miR-155. Proc Natl Acad Sci U S A (2009) 5.30
Export of microRNAs and microRNA-protective protein by mammalian cells. Nucleic Acids Res (2010) 5.29
MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators. Mol Cell Biol (2008) 5.21
Foxp3-dependent microRNA155 confers competitive fitness to regulatory T cells by targeting SOCS1 protein. Immunity (2009) 5.10
MicroRNA-192 in diabetic kidney glomeruli and its function in TGF-beta-induced collagen expression via inhibition of E-box repressors. Proc Natl Acad Sci U S A (2007) 4.92
Integrin ligands at a glance. J Cell Sci (2006) 4.76
miR-221&222 regulate TRAIL resistance and enhance tumorigenicity through PTEN and TIMP3 downregulation. Cancer Cell (2009) 4.48
Osteoarthritis: a disease of the joint as an organ. Arthritis Rheum (2012) 4.28
RIP-Chip: the isolation and identification of mRNAs, microRNAs and protein components of ribonucleoprotein complexes from cell extracts. Nat Protoc (2006) 4.28
Altered expression of MicroRNA in synovial fibroblasts and synovial tissue in rheumatoid arthritis. Arthritis Rheum (2008) 4.08
Circulating microRNAs: novel biomarkers and extracellular communicators in cardiovascular disease? Circ Res (2012) 4.06
MicroRNA 29c is down-regulated in nasopharyngeal carcinomas, up-regulating mRNAs encoding extracellular matrix proteins. Proc Natl Acad Sci U S A (2008) 4.06
miR-212 and miR-132 are required for epithelial stromal interactions necessary for mouse mammary gland development. Nat Genet (2010) 4.06
TGF-beta activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN. Nat Cell Biol (2009) 4.05
Desperately seeking microRNA targets. Nat Struct Mol Biol (2010) 3.85
Two-piconewton slip bond between fibronectin and the cytoskeleton depends on talin. Nature (2003) 3.70
Target mRNA abundance dilutes microRNA and siRNA activity. Mol Syst Biol (2010) 3.37
Redefining microRNA targets. Curr Biol (2009) 3.37
Extracellular matrix degradation and remodeling in development and disease. Cold Spring Harb Perspect Biol (2011) 3.36
Microvesicles: mediators of extracellular communication during cancer progression. J Cell Sci (2010) 3.35
Induction and regulatory function of miR-9 in human monocytes and neutrophils exposed to proinflammatory signals. Proc Natl Acad Sci U S A (2009) 3.27
A novel function for tissue inhibitor of metalloproteinases-3 (TIMP3): inhibition of angiogenesis by blockage of VEGF binding to VEGF receptor-2. Nat Med (2003) 3.20
Versican: a versatile extracellular matrix proteoglycan in cell biology. Curr Opin Cell Biol (2002) 3.00
Up-regulated microRNA-143 transcribed by nuclear factor kappa B enhances hepatocarcinoma metastasis by repressing fibronectin expression. Hepatology (2009) 2.96
Integrin signalling adaptors: not only figurants in the cancer story. Nat Rev Cancer (2010) 2.94
Extracellular matrix metabolism in diabetic nephropathy. J Am Soc Nephrol (2003) 2.85
The extracellular matrix in development and morphogenesis: a dynamic view. Dev Biol (2009) 2.82
The cartilage specific microRNA-140 targets histone deacetylase 4 in mouse cells. FEBS Lett (2006) 2.79
MicroRNA-377 is up-regulated and can lead to increased fibronectin production in diabetic nephropathy. FASEB J (2008) 2.75
CD44 in cancer progression: adhesion, migration and growth regulation. J Mol Histol (2004) 2.71
MicroRNA-140 plays dual roles in both cartilage development and homeostasis. Genes Dev (2010) 2.70
Integrative microRNA and proteomic approaches identify novel osteoarthritis genes and their collaborative metabolic and inflammatory networks. PLoS One (2008) 2.65
Secreted microRNAs: a new form of intercellular communication. Trends Cell Biol (2012) 2.62
MicroRNA-29, a key regulator of collagen expression in systemic sclerosis. Arthritis Rheum (2010) 2.53
MicroRNA MiR-17 retards tissue growth and represses fibronectin expression. Nat Cell Biol (2009) 2.49
Tumor-host interactions: a far-reaching relationship. J Clin Oncol (2010) 2.48
MicroRNA-133a protects against myocardial fibrosis and modulates electrical repolarization without affecting hypertrophy in pressure-overloaded adult hearts. Circ Res (2009) 2.40
Expression of CD44 variant proteins in human colorectal cancer is related to tumor progression. Cancer Res (1993) 2.39
MicroRNA miR-93 promotes tumor growth and angiogenesis by targeting integrin-β8. Oncogene (2010) 2.37
Transforming growth factor-beta and fibrosis. World J Gastroenterol (2007) 2.35
TGFbeta-mediated upregulation of hepatic miR-181b promotes hepatocarcinogenesis by targeting TIMP3. Oncogene (2009) 2.33
A 3'-untranslated region (3'UTR) induces organ adhesion by regulating miR-199a* functions. PLoS One (2009) 2.24
MicroRNA-21 is overexpressed in human cholangiocarcinoma and regulates programmed cell death 4 and tissue inhibitor of metalloproteinase 3. Hepatology (2009) 2.23
Tenascin-C induced signaling in cancer. Cancer Lett (2006) 2.21
Up-regulation of microRNA-155 in macrophages contributes to increased tumor necrosis factor {alpha} (TNF{alpha}) production via increased mRNA half-life in alcoholic liver disease. J Biol Chem (2010) 2.16
Expression of CD44 3'-untranslated region regulates endogenous microRNA functions in tumorigenesis and angiogenesis. Nucleic Acids Res (2010) 2.15
Prognostic breast cancer signature identified from 3D culture model accurately predicts clinical outcome across independent datasets. PLoS One (2008) 2.12
Expression of distinct RNAs from 3' untranslated regions. Nucleic Acids Res (2010) 2.08
Type I transforming growth factor beta receptor binds to and activates phosphatidylinositol 3-kinase. J Biol Chem (2005) 2.04
GATA3 suppresses metastasis and modulates the tumour microenvironment by regulating microRNA-29b expression. Nat Cell Biol (2013) 2.03
MicroRNA-140 is expressed in differentiated human articular chondrocytes and modulates interleukin-1 responses. Arthritis Rheum (2009) 1.99
Expression of versican 3'-untranslated region modulates endogenous microRNA functions. PLoS One (2010) 1.94
MicroRNA miR-378 regulates nephronectin expression modulating osteoblast differentiation by targeting GalNT-7. PLoS One (2009) 1.88
The skeleton: a multi-functional complex organ: the growth plate chondrocyte and endochondral ossification. J Endocrinol (2011) 1.85
Collagen type I induces disruption of E-cadherin-mediated cell-cell contacts and promotes proliferation of pancreatic carcinoma cells. Cancer Res (2006) 1.84
Expression of MicroRNA-146a in osteoarthritis cartilage. Arthritis Rheum (2009) 1.84
Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c. Circ Res (2013) 1.81
The role of tenascin-C in tissue injury and tumorigenesis. J Cell Commun Signal (2009) 1.72
Plasma and cellular fibronectin: distinct and independent functions during tissue repair. Fibrogenesis Tissue Repair (2011) 1.41
Intrinsic danger: activation of Toll-like receptors in rheumatoid arthritis. Rheumatology (Oxford) (2011) 1.29
Transcriptional regulation of the endogenous danger signal tenascin-C: a novel autocrine loop in inflammation. J Immunol (2010) 1.25
Expression and immune function of tenascin-C. Crit Rev Immunol (2011) 1.04
Endogenous control of immunity against infection: tenascin-C regulates TLR4-mediated inflammation via microRNA-155. Cell Rep (2012) 1.04
Unraveling the signaling pathways promoting fibrosis in Dupuytren's disease reveals TNF as a therapeutic target. Proc Natl Acad Sci U S A (2013) 1.03
Self-assembled monolayers of alpha,omega-diphosphonic acids on Ti enable complete or spatially controlled surface derivatization. Langmuir (2004) 0.97
The alarmin IL-33 is a notch target in quiescent endothelial cells. Am J Pathol (2012) 0.94
Endogenous activation of adaptive immunity: tenascin-C drives interleukin-17 synthesis in murine arthritic joint disease. Arthritis Rheum (2012) 0.89
Toll-like receptor signaling: common pathways that drive cardiovascular disease and rheumatoid arthritis. Arthritis Care Res (Hoboken) (2011) 0.85
Cryptic domains of tenascin-C differentially control fibronectin fibrillogenesis. Matrix Biol (2010) 0.85
Tenascin-C: Form versus function. Cell Adh Migr (2015) 0.83
Identification of novel and distinct binding sites within tenascin-C for soluble and fibrillar fibronectin. J Biol Chem (2011) 0.82
Isometric contraction of Dupuytren's myofibroblasts is inhibited by blocking intercellular junctions. J Invest Dermatol (2013) 0.82
Raised circulating tenascin-C in rheumatoid arthritis. Arthritis Res Ther (2012) 0.80