Published in Proc Natl Acad Sci U S A on April 01, 1989
Induction of antibodies to the envelope protein of the human immunodeficiency virus by immunization with monoclonal anti-idiotypes. Proc Natl Acad Sci U S A (1991) 0.91
Ig Constant Region Effects on Variable Region Structure and Function. Front Microbiol (2016) 0.90
Generation and analysis of clonal IgM- and IgG-producing human B cell lines expressing an anti-DNA-associated idiotype. J Clin Invest (1991) 0.87
Nucleotide changes in sequential variants of influenza virus hemagglutinin genes and molecular structures of corresponding monoclonal antibodies specific for each variant. Proc Natl Acad Sci U S A (1989) 0.79
New nucleotide sequence data on the EMBL File Server. Nucleic Acids Res (1989) 0.75
Molecular characterization of monoclonal CRIA-positive anti-arsonate antibodies derived from idiotype-negative mice bearing a light chain polymorphism. Proc Natl Acad Sci U S A (1993) 0.75
New nucleotide sequence data on the EMBL File Server. Nucleic Acids Res (1989) 0.75
Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry (1979) 180.95
Purification of biologically active globin messenger RNA by chromatography on oligothymidylic acid-cellulose. Proc Natl Acad Sci U S A (1972) 83.88
Prediction of protein antigenic determinants from amino acid sequences. Proc Natl Acad Sci U S A (1981) 32.98
Organization, structure, and assembly of immunoglobulin heavy chain diversity DNA segments. J Exp Med (1982) 5.37
Clusters of point mutations are found exclusively around rearranged antibody variable genes. Proc Natl Acad Sci U S A (1983) 2.38
Idiotype-anti-idiotype regulation. I. Immunization with a levan-binding myeloma protein leads to the appearance of auto-anti-(anti-idiotype) antibodies and to the activation of silent clones. J Exp Med (1981) 2.28
Variable region sequences of murine IgM anti-IgG monoclonal autoantibodies (rheumatoid factors). A structural explanation for the high frequency of IgM anti-IgG B cells. J Exp Med (1986) 2.04
VH genes encoding the immune response to beta-(1,6)-galactan: somatic mutation in IgM molecules. EMBO J (1984) 1.98
Immune response to levan. I. Kinetics and ontogeny of anti-levan and anti-inulin antibody response and of expression of cross-reactive idiotype. J Immunol (1978) 1.57
Shared idiotypes and restricted immunoglobulin variable region heavy chain genes characterize murine autoantibodies of various specificities. J Clin Invest (1986) 1.48
Idiotype-anti-idiotype network. II. Activation of silent clones by treatment at birth with idiotypes is associated with the expansion of idiotype-specific helper T cells. J Exp Med (1982) 1.43
Novel V genes encode virtually identical variable regions of six murine monoclonal anti-bromelain-treated red blood cell autoantibodies. J Immunol (1987) 1.33
Different VL and VH germ-line genes are used to produce similar combining sites with specificity for alpha(1----6)dextrans. J Immunol (1987) 1.27
Neonatal treatment with low doses of anti-idiotypic antibody leads to the expression of a silent clone. J Exp Med (1981) 1.24
Specificities and V genes encoding monoclonal autoantibodies from viable motheaten mice. J Exp Med (1988) 1.23
Fine specificity, idiotypy, and nature of cloned heavy-chain variable region genes of murine monoclonal rheumatoid factor antibodies. Proc Natl Acad Sci U S A (1986) 1.10
Generation of monoclonal rheumatoid factors after immunization with collagen II-anti-collagen II immune complexes. An anti-idiotypic antibody to anti-collagen II is also a rheumatoid factor. Scand J Immunol (1986) 1.07
Idiotype-anti-idiotype interactions and the control of the anti-beta (2 leads to 6) polyfructosan response in the mouse: specificity and idiotypy of anti-ABPC48 anti-idiotypic monoclonal antibodies. Eur J Immunol (1981) 1.03
Characterization of variable-region genes and shared crossreactive idiotypes of antibodies specific for antigens of various influenza viruses. Viral Immunol (1987) 1.01
Towards a unified theory of immunoglobulin structure-function relations. Immunol Rev (1986) 1.00
The complete V domain amino acid sequences of two myeloma inulin-binding proteins. J Immunol (1982) 0.98
Identity of the V kappa 10-Ars-A gene segments of the A/J and BALB/c strains. Proc Natl Acad Sci U S A (1987) 0.95
High frequency of autoantibodies bearing cross-reactive idiotopes among hybridomas using VH7183 genes prepared from normal and autoimmune murine strains. J Clin Invest (1987) 0.95
Immunochemical and molecular characterization of regulatory idiotopes expressed by monoclonal antibodies exhibiting or lacking beta 2-6 fructosan binding activity. J Exp Med (1985) 0.92
Alternative splicing patterns in an aberrantly rearranged immunoglobulin kappa-light-chain gene. Proc Natl Acad Sci U S A (1985) 0.91
Localized deletion-insertion mutations: a major factor in the evolution of immunoglobulin structural variability. J Immunol (1976) 0.89
Correlation between D region structure and antigen-binding specificity: evidences from the comparison of closely related immunoglobulin VH sequences. Ann Immunol (Paris) (1982) 0.83
The VK gene expressed by BALB/c ABPC48 cross-reactive idiotypes induced by anti-idiotypic immunization is identical to that of BALB/c anti-oxazolone and A/J anti-arsonate antibodies. J Immunol (1985) 0.80
Oligomeric structure of gp41, the transmembrane protein of human immunodeficiency virus type 1. J Virol (1989) 4.07
Defining criteria for autoimmune diseases (Witebsky's postulates revisited) Immunol Today (1993) 3.81
Repair of DNA double strand breaks by non-homologous end joining. Biochimie (2003) 2.65
Cellular basis of regulation of expression of idiotype. I. T-suppressor cells specific for MOPC 460 idiotype regulate the expression of cells secreting anti-TNP antibodies bearing 460 idiotype. J Exp Med (1979) 2.53
Mitogenic effect of bacterial peptidoglycans possessing adjuvant activity. J Immunol (1975) 2.15
Presentation of a viral T cell epitope expressed in the CDR3 region of a self immunoglobulin molecule. Science (1993) 1.96
Influenza A virus transfectants with chimeric hemagglutinins containing epitopes from different subtypes. J Virol (1992) 1.88
The XRCC4 gene product is a target for and interacts with the DNA-dependent protein kinase. J Biol Chem (1998) 1.87
Cellular basis of regulation of expression of idiotype. II. Immunity to anti-MOPC-460 idiotype antibodies increases the level of anti-trinitrophenyl antibodies bearing 460 idiotypes. J Exp Med (1979) 1.76
Chimeric influenza virus induces neutralizing antibodies and cytotoxic T cells against human immunodeficiency virus type 1. J Virol (1993) 1.70
Both V(D)J recombination and radioresistance require DNA-PK kinase activity, though minimal levels suffice for V(D)J recombination. Nucleic Acids Res (2000) 1.65
Blastic transformtion of mouse spleen lymphocytes by a water-soluble mitogen extracted from Nocardia. Proc Natl Acad Sci U S A (1974) 1.62
Immune response to levan. I. Kinetics and ontogeny of anti-levan and anti-inulin antibody response and of expression of cross-reactive idiotype. J Immunol (1978) 1.57
Proteases as mitogens. The Effect of trypsin and pronase on mouse and human lymphocytes. Exp Cell Res (1974) 1.56
Isolation of mitogenic and adjuvant active fractions from various species of Nocardiae. Infect Immun (1975) 1.54
Identification of a new V kappa gene family that is highly expressed in hybridomas from an autoimmune mouse strain. J Immunol (1990) 1.46
Conditions that induce tolerance in mature CD4+ T cells. J Exp Med (1997) 1.45
A kinase-negative mutation of DNA-PK(CS) in equine SCID results in defective coding and signal joint formation. J Immunol (1997) 1.41
Mitogenic effect of a water-soluble extract of Nocardia opaca: a comparative study with some bacterial adjuvants on spleen and peripheral lymphocytes of four mammalian species. J Immunol (1974) 1.40
Target cells for the activity of a synthetic adjuvant: muramyl dipeptide. Cell Immunol (1977) 1.36
Immune response to levan. III. The capacity to produce anti-inulin antibodies and cross-reactive idiotypes appears late in ontogeny. J Immunol (1979) 1.34
A human T-independent B lymphocyte mitogen extracted from Nocardia opaca. J Immunol (1976) 1.33
Equine severe combined immunodeficiency: a defect in V(D)J recombination and DNA-dependent protein kinase activity. Proc Natl Acad Sci U S A (1995) 1.27
Blast transformation of rabbit B-derived lymphocytes by a mitogen extracted from Nocardia. J Immunol (1975) 1.25
Neonatal treatment with low doses of anti-idiotypic antibody leads to the expression of a silent clone. J Exp Med (1981) 1.24
[Serological evolution of infection by Plasmodium malariae: variations of fluorescent antibody titre after radical treatment]. Bull World Health Organ (1969) 1.22
Regulation of human B cell function by recombinant CD40 ligand and other TNF-related ligands. J Immunol (1995) 1.19
Polyclonal activation of human B lymphocytes by Nocardia water soluble mitogen (NWSM). Immunol Rev (1979) 1.19
Murine V kappa gene expression does not follow the VH paradigm. J Exp Med (1989) 1.19
Cell suppression in PPD-induced blast specific response of human peripheral blood lymphocytes. Clin Exp Immunol (1976) 1.18
Presence and subcellular localization of two distinct mitogenic fractions in the cells of Nocardia rubra and Nocardia opaca: preparation of soluble mitogenic peptidoglycan fractions. Infect Immun (1976) 1.18
The fluorescent antibody technique in the estimation of immunity in patients infected with Plasmodium malariae. Trans R Soc Trop Med Hyg (1966) 1.17
[The value of the immunofluorescent reaction in the detection of asymptomatic parasitemia due to Plasmodium malariae]. Bull World Health Organ (1967) 1.17
Ligation of CD40 induces sterile transcripts of multiple Ig H chain isotypes in human B cells. J Immunol (1994) 1.14
Regulation of the anti-inulin antibody response by a nonallotype-linked gene. J Exp Med (1980) 1.14
Lack of skin fibrosis in tight skin (TSK) mice with targeted mutation in the interleukin-4R alpha and transforming growth factor-beta genes. J Invest Dermatol (2001) 1.13
Mitogenic analysis of murine B-cell heterogeneity. J Exp Med (1978) 1.13
T cell receptor V beta gene bias in rheumatoid arthritis. J Clin Invest (1993) 1.12
Modulation of terminal deoxynucleotidyltransferase activity by the DNA-dependent protein kinase. J Immunol (1999) 1.12
Pharmacokinetics and tolerability of a new intravenous immunoglobulin preparation, IGIV-C, 10% (Gamunex, 10%). Vox Sang (2003) 1.10
Genetic and cellular regulation of the expression of specific antibody idiotypes in the anti-polyfructosan immune response. Ann Immunol (Paris) (1979) 1.10
Transfer of antigenic macromolecules from macrophages to lymphocytes. I. Autoradiographic and quantitative study of ( 14 C)endotoxin and ( 125 I)haemocyanin transfer. Immunology (1972) 1.09
Anti-immunoglobulin antibodies. I. Expression of cross-reactive idiotypes and Ir gene control of the response to IgG2a of the b allotype. J Exp Med (1980) 1.08
Idiotypic determinants of rabbit B- and T-derived lymphocytes. Immunol Rev (1977) 1.04
Cellular mechanisms involved in protection against influenza virus infection in transgenic mice expressing a TCR receptor specific for class II hemagglutinin peptide in CD4+ and CD8+ T cells. J Immunol (1998) 1.03
Immune response to levan. II. T independence of suppression of cross-reactive idiotypes by anti-idiotype antibodies. J Immunol (1979) 1.02
Enhanced protection against influenza virus of mice immunized as newborns with a mixture of plasmids expressing hemagglutinin and nucleoprotein. Vaccine (1998) 1.01
DNA immunization of newborn mice with a plasmid-expressing nucleoprotein of influenza virus. Viral Immunol (1996) 0.99
Idiotype vaccines. Ann Inst Pasteur Immunol (1985) 0.98
Direct and indirect suppression induced by anti-idiotype antibody in the inulin-bacterial levan antigenic system. Mol Immunol (1979) 0.98
IgM anti-Fc gamma R autoantibodies trigger neutrophil degranulation. J Exp Med (1991) 0.96
Synergistic genetic defect in B-lymphocyte function. I. Defective responses to B-cell stimulants and their genetic basis. J Exp Med (1980) 0.96
Cells expressing an H chain Ig gene carrying a viral T cell epitope are lysed by specific cytolytic T cells. J Immunol (1992) 0.96
Identity of the V kappa 10-Ars-A gene segments of the A/J and BALB/c strains. Proc Natl Acad Sci U S A (1987) 0.95
High frequency of autoantibodies bearing cross-reactive idiotopes among hybridomas using VH7183 genes prepared from normal and autoimmune murine strains. J Clin Invest (1987) 0.95
Stochastic pairing of heavy-chain and kappa light-chain variable gene families occurs in polyclonally activated B cells. Proc Natl Acad Sci U S A (1990) 0.94
Pinocytosis of some exotoxins by leucocytes. Pinocytosis of diphtheria toxin and of dick erythrotoxin. Exp Cell Res (1966) 0.94
Stimulation of lymphocytes by purified protein derivative: suppression by cells from human vaccinated with Bacille Calmette-Guérin. J Infect Dis (1976) 0.94
Histochemical and cytoenzymological studies in myositis ossificans. Acta Histochem (1967) 0.93
Transfer of antigen from macrophages to lymphocytes. II. Immunological significance of the transfer of lipopolysaccharide. Immunology (1973) 0.93
DNA-dependent protein kinase phosphorylation of IkappaB alpha and IkappaB beta regulates NF-kappaB DNA binding properties. Mol Cell Biol (1998) 0.93
Induction of antihemagglutinin antibodies by polyclonal antiidiotype antibodies. Viral Immunol (1993) 0.92
Immunochemical and molecular characterization of regulatory idiotopes expressed by monoclonal antibodies exhibiting or lacking beta 2-6 fructosan binding activity. J Exp Med (1985) 0.92
[Ultrastructure of guinea pig macrophages]. Ann Inst Pasteur (Paris) (1971) 0.92
CD27-CD27 ligand/CD70 interactions enhance alloantigen-induced proliferation and cytolytic activity in CD8+ T lymphocytes. J Immunol (1995) 0.92
Primary immunodeficiency diseases: a practical guide for clinicians. Postgrad Med J (2009) 0.92
Induction of antibodies to the envelope protein of the human immunodeficiency virus by immunization with monoclonal anti-idiotypes. Proc Natl Acad Sci U S A (1991) 0.91
A novel point mutation in CD18 causing the expression of dysfunctional CD11/CD18 leucocyte integrins in a patient with leucocyte adhesion deficiency (LAD). Clin Exp Immunol (2000) 0.91
Biased usage of certain Vk gene families by autoantibodies and their polymorphism in autoimmune mice. Mol Immunol (1988) 0.91
New perspectives on immunointervention in autoimmune diseases. Immunol Today (1990) 0.90
The molecular genetics of the arsonate idiotypic system of A/J mice. Adv Immunol (1988) 0.90
Biological activities of endotoxins detoxified by alkylation. Infect Immun (1975) 0.90
Internal antigen and immune network. Proc Soc Exp Biol Med (1985) 0.90
Anti-immunoglobulin antibodies. II. Expression of individual and cross-reactive idiotypes on syngeneic and homologous anti-idiotype antibodies. J Immunol (1981) 0.90
Autoantibodies of various specificities encoded by genes from the VH J558 family bind to foreign antigens and share idiotopes of antibodies specific for self and foreign antigens. J Exp Med (1987) 0.89
Sequences of the VH and VL regions of murine monoclonal antibodies against 3-fucosyllactosamine. J Immunol (1988) 0.89
Induction of humoral and cellular immunity against influenza virus by immunization of newborn mice with a plasmid bearing a hemagglutinin gene. Int Immunol (1997) 0.88
[Endocytotic capacity of normal and in vitro transformed guinea pig lymph node lymphocytes]. Ann Inst Pasteur (Paris) (1969) 0.88
Induction of skin fibrosis in mice expressing a mutated fibrillin-1 gene. Mol Med (2000) 0.88
Inhibition of mitogen induced blastogenesis by 5'-deoxy-5'-S-iso-butyl adenosine. Biochem Biophys Res Commun (1976) 0.88
Immunoglobulin D(H) recombination signal sequence targeting: effect of D(H) coding and flanking regions and recombination partner. J Immunol (1996) 0.88
Migration inhibition factor and blast transformation in human lymphoid cultures stimulated by different agents. Clin Exp Immunol (1974) 0.88
The mitogenic effect of lipopolysaccharide. Metabolic processing of lipopolysaccharide by mouse lymphocytes. Cell Immunol (1977) 0.88
[Localization by ultrastructural autoradiography of 3H-galactose in transformed lymphocytes]. C R Acad Sci Hebd Seances Acad Sci D (1969) 0.87
Assembly of IgH CDR3: mechanism, regulation, and influence on antibody diversity. Int Rev Immunol (1992) 0.87
Origin of the autoreactive anti-type II collagen response. II. Specificities, antibody isotypes and usage of V gene families of anti-type II collagen B cells. J Immunol (1989) 0.86
Autoantibodies directed against different classes of Fc gamma R are found in sera of autoimmune patients. J Immunol (1993) 0.86
Immune response of neonates elicited by somatic transgene vaccination with naked DNA. Front Biosci (1997) 0.85
Kinetics of generation and persistence on membrane class II molecules of a viral peptide expressed on foreign and self proteins. J Immunol (1996) 0.85
Collagen as a model system to investigate the use of aspirin as an inhibitor of protein glycation and crosslinking. Micron (2001) 0.85
Primary structure of IgE monoclonal antibodies expressing an intrastrain crossreactive idiotype. J Exp Med (1986) 0.85
The human and murine influenza-specific B cell repertoires share a common idiotope. J Immunol (1987) 0.84
[Antitumoral effect of peritoneal macrophages activated by a water-soluble adjuvant of mycobacterial origin]. C R Acad Sci Hebd Seances Acad Sci D (1974) 0.84
Structure of the lymphocyte membrane. IV. Cell coat of lymphocytes obtained from various lymphoid organs in chicken and mice. Ann Immunol (Paris) (1973) 0.84
Differential regional distribution of mucopolysaccharides in the human epiphyseal cartilage matrix in normal and pathologic conditions. Virchows Arch Pathol Anat Physiol Klin Med (1967) 0.84