Peptide sequencing and site-directed mutagenesis identify tyrosine-727 as the active site tyrosine of Saccharomyces cerevisiae DNA topoisomerase I.

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Published in Proc Natl Acad Sci U S A on May 01, 1989

Authors

R M Lynn1, M A Bjornsti, P R Caron, J C Wang

Author Affiliations

1: Department of Biochemistry and Molecular Biology, Harvard University, Cambridge, MA 02138.

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