Published in EMBO J on November 01, 1989
The ompA 5' untranslated RNA segment functions in Escherichia coli as a growth-rate-regulated mRNA stabilizer whose activity is unrelated to translational efficiency. J Bacteriol (1990) 2.68
Control of replication of plasmid R1: the duplex between the antisense RNA, CopA, and its target, CopT, is processed specifically in vivo and in vitro by RNase III. EMBO J (1990) 2.31
mRNA decay in Escherichia coli comes of age. J Bacteriol (2002) 2.20
Regulation of ribonuclease III processing by double-helical sequence antideterminants. Proc Natl Acad Sci U S A (1997) 2.04
RNA processing and degradation in Bacillus subtilis. Microbiol Mol Biol Rev (2003) 1.86
Emerging features of mRNA decay in bacteria. RNA (2000) 1.68
Analysis of mRNA decay and rRNA processing in Escherichia coli multiple mutants carrying a deletion in RNase III. J Bacteriol (1993) 1.59
Transcription and decay of the lac messenger: role of an intergenic terminator. J Bacteriol (1991) 1.58
The phylogenetic distribution of bacterial ribonucleases. Nucleic Acids Res (2002) 1.54
Cleavages in the 5' region of the ompA and bla mRNA control stability: studies with an E. coli mutant altering mRNA stability and a novel endoribonuclease. EMBO J (1990) 1.49
The universally conserved prokaryotic GTPases. Microbiol Mol Biol Rev (2011) 1.47
The cleavage specificity of RNase III. Nucleic Acids Res (1990) 1.46
Suppression of insertions in the complex pdxJ operon of Escherichia coli K-12 by lon and other mutations. J Bacteriol (1992) 1.40
Locating essential Escherichia coli genes by using mini-Tn10 transposons: the pdxJ operon. J Bacteriol (1992) 1.40
S. pombe pac1+, whose overexpression inhibits sexual development, encodes a ribonuclease III-like RNase. EMBO J (1991) 1.39
A GTP-binding protein (Era) has an essential role in growth rate and cell cycle control in Escherichia coli. J Bacteriol (1991) 1.37
Analysis of Escherichia coli RNase E and RNase III activity in vivo using tiling microarrays. Nucleic Acids Res (2010) 1.32
PNPase autocontrols its expression by degrading a double-stranded structure in the pnp mRNA leader. EMBO J (2001) 1.27
A conserved sequence element in ribonuclease III processing signals is not required for accurate in vitro enzymatic cleavage. Nucleic Acids Res (1991) 1.25
tmRNA regulates synthesis of the ArfA ribosome rescue factor. Mol Microbiol (2011) 1.24
A Streptomyces coelicolor antibiotic regulatory gene, absB, encodes an RNase III homolog. J Bacteriol (1999) 1.20
Global regulatory functions of the Staphylococcus aureus endoribonuclease III in gene expression. PLoS Genet (2012) 1.17
Bacillus subtilis RNase III gene: cloning, function of the gene in Escherichia coli, and construction of Bacillus subtilis strains with altered rnc loci. J Bacteriol (1997) 1.14
Polyadenylation of a functional mRNA controls gene expression in Escherichia coli. Nucleic Acids Res (2007) 1.12
Translation elongation factor Tu cleaved by a phage-exclusion system. Proc Natl Acad Sci U S A (1994) 1.07
Characterization of the biochemical properties of recombinant ribonuclease III. Nucleic Acids Res (1990) 1.07
mRNA processing independent of RNase III and RNase E in the expression of the F1845 fimbrial adhesin of Escherichia coli. Proc Natl Acad Sci U S A (1993) 1.07
Initiation of mRNA decay in bacteria. Cell Mol Life Sci (2013) 1.04
Translation of the adhE transcript to produce ethanol dehydrogenase requires RNase III cleavage in Escherichia coli. J Bacteriol (1996) 1.02
Degradation of pufLMX mRNA in Rhodobacter capsulatus is initiated by nonrandom endonucleolytic cleavage. J Bacteriol (1990) 1.00
A novel endoribonuclease, RNase LS, in Escherichia coli. Genetics (2005) 0.97
Metabolic engineering in the -omics era: elucidating and modulating regulatory networks. Microbiol Mol Biol Rev (2005) 0.97
Regulated RNA stability in the Gram positives. Curr Opin Microbiol (2011) 0.96
RNA-Seq and RNA immunoprecipitation analyses of the transcriptome of Streptomyces coelicolor identify substrates for RNase III. J Bacteriol (2012) 0.94
Characterization of mutations affecting the Escherichia coli essential GTPase era that suppress two temperature-sensitive dnaG alleles. J Bacteriol (1997) 0.94
Rescue of the RNA phage genome from RNase III cleavage. Nucleic Acids Res (1997) 0.93
The Escherichia coli mrsC gene is required for cell growth and mRNA decay. J Bacteriol (1998) 0.92
MicroRNA-independent roles of the RNase III enzymes Drosha and Dicer. Open Biol (2013) 0.91
Escherichia coli endoribonucleases involved in cleavage of bacteriophage T4 mRNAs. J Bacteriol (2003) 0.90
Ethidium-dependent uncoupling of substrate binding and cleavage by Escherichia coli ribonuclease III. Nucleic Acids Res (2001) 0.86
Escherichia coli mrsC is an allele of hflB, encoding a membrane-associated ATPase and protease that is required for mRNA decay. J Bacteriol (1998) 0.86
When ribonucleases come into play in pathogens: a survey of gram-positive bacteria. Int J Microbiol (2012) 0.85
How bacterial cells keep ribonucleases under control. FEMS Microbiol Rev (2015) 0.84
Ribonuclease M5 has few, if any, mRNA substrates in Bacillus subtilis. J Bacteriol (2002) 0.84
Importance of cis determinants and nitrogenase activity in regulated stability of the Klebsiella pneumoniae nitrogenase structural gene mRNA. J Bacteriol (1999) 0.84
RNase III controls the degradation of corA mRNA in Escherichia coli. J Bacteriol (2012) 0.84
IscR regulates RNase LS activity by repressing rnlA transcription. Genetics (2010) 0.83
RNA Degradation in Staphylococcus aureus: Diversity of Ribonucleases and Their Impact. Int J Genomics (2015) 0.82
Cloning and analysis of the rnc-era-recO operon from Pseudomonas aeruginosa. J Bacteriol (1999) 0.81
Processing in the 5' region of the pnp transcript facilitates the site-specific endonucleolytic cleavages of mRNA. Nucleic Acids Res (1992) 0.79
RNA Sequencing Identifies New RNase III Cleavage Sites in Escherichia coli and Reveals Increased Regulation of mRNA. MBio (2017) 0.77
RNase III is required for actinomycin production in Streptomyces antibioticus. Appl Environ Microbiol (2013) 0.77
Combined computational and experimental analysis of a complex of ribonuclease III and the regulatory macrodomain protein, YmdB. Proteins (2015) 0.77
The sequences and activities of RegB endoribonucleases of T4-related bacteriophages. Nucleic Acids Res (2004) 0.77
Mapping of internal monophosphate 5' ends of Bacillus subtilis messenger RNAs and ribosomal RNAs in wild-type and ribonuclease-mutant strains. Nucleic Acids Res (2016) 0.76
Mechanism of Ribonuclease III Catalytic Regulation by Serine Phosphorylation. Sci Rep (2016) 0.75
Optimal computer folding of large RNA sequences using thermodynamics and auxiliary information. Nucleic Acids Res (1981) 61.59
Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene. Nature (1984) 24.45
Complete nucleotide sequence of bacteriophage T7 DNA and the locations of T7 genetic elements. J Mol Biol (1983) 19.98
Vectors for selective expression of cloned DNAs by T7 RNA polymerase. Gene (1987) 17.98
Evidence for two functional gal promoters in intact Escherichia coli cells. J Biol Chem (1981) 17.42
Unstable ribonucleic acid revealed by pulse labelling of Escherichia coli. Nature (1961) 11.20
Consensus sequence for Escherichia coli heat shock gene promoters. Proc Natl Acad Sci U S A (1985) 6.04
Complementary sequences 1700 nucleotides apart form a ribonuclease III cleavage site in Escherichia coli ribosomal precursor RNA. Proc Natl Acad Sci U S A (1978) 4.90
The ribonuclease III site flanking 23S sequences in the 30S ribosomal precursor RNA of E. coli. Cell (1980) 4.19
Differential expression of photosynthesis genes in R. capsulata results from segmental differences in stability within the polycistronic rxcA transcript. Cell (1985) 4.15
Attenuation and processing of RNA from the rplJL--rpoBC transcription unit of Escherichia coli. Proc Natl Acad Sci U S A (1980) 3.86
Differential stringent control of the tandem E. coli ribosomal RNA promoters from the rrnA operon expressed in vivo in multicopy plasmids. Cell (1983) 3.33
Estrogen stabilizes vitellogenin mRNA against cytoplasmic degradation. Cell (1983) 3.13
Growth-rate dependent regulation of mRNA stability in Escherichia coli. Nature (1984) 3.06
Differential mRNA stability controls relative gene expression within a polycistronic operon. Cell (1987) 2.79
The first step in the functional inactivation of the Escherichia coli polynucleotide phosphorylase messenger is a ribonuclease III processing at the 5' end. EMBO J (1987) 2.77
Genetic analysis of the rnc operon of Escherichia coli. J Bacteriol (1989) 2.72
Nucleolytic processing of ribonucleic acid transcripts in procaryotes. Microbiol Rev (1986) 2.70
Site-specific endonucleolytic cleavages and the regulation of stability of E. coli ompA mRNA. Cell (1988) 2.68
An intercistronic stem-loop structure functions as an mRNA decay terminator necessary but insufficient for puf mRNA stability. Cell (1988) 2.53
Genetic mapping of a mutation that causes ribonucleases III deficiency in Escherichia coli. J Bacteriol (1975) 2.50
Maturation of Escherichia coli tryptophan operon mRNA: evidence for 3' exonucleolytic processing after rho-dependent termination. EMBO J (1985) 2.46
Processing of mRNA by ribonuclease III regulates expression of gene 1.2 of bacteriophage T7. Cell (1981) 2.44
Translation and mRNA decay. Mol Gen Genet (1978) 2.40
A GTP-binding protein of Escherichia coli has homology to yeast RAS proteins. Proc Natl Acad Sci U S A (1986) 2.32
Effect of premature termination of translation on mRNA stability depends on the site of ribosome release. Proc Natl Acad Sci U S A (1987) 2.24
Removal of a terminator structure by RNA processing regulates int gene expression. J Mol Biol (1984) 2.13
Induced mRNA stability in Bacillus subtilis. Proc Natl Acad Sci U S A (1987) 2.13
Initiation, attenuation and RNase III processing of transcripts from the Escherichia coli operon encoding ribosomal protein S15 and polynucleotide phosphorylase. J Mol Biol (1986) 2.06
The stability of bacteriophage T4 gene 32 mRNA: a 5' leader sequence that can stabilize mRNA transcripts. Cell (1985) 1.98
E. coli RNases: making sense of alphabet soup. Cell (1985) 1.86
The DNA sequence of the gene (rnc) encoding ribonuclease III of Escherichia coli. Nucleic Acids Res (1985) 1.72
Inefficient translation initiation causes premature transcription termination in the lacZ gene. Cell (1986) 1.63
Evidence for endonucleolytic attack in decay of lac messenger RNA in Escherichia coli. J Mol Biol (1974) 1.58
OOP RNA, produced from multicopy plasmids, inhibits lambda cII gene expression through an RNase III-dependent mechanism. Genes Dev (1987) 1.57
DNA sequencing of the Escherichia coli ribonuclease III gene and its mutations. Mol Gen Genet (1985) 1.56
The synthesis of some proteins is affected in RNA processing mutants of Escherichia coli. Biochem Biophys Res Commun (1980) 1.56
RNase III stimulates the translation of the cIII gene of bacteriophage lambda. Proc Natl Acad Sci U S A (1987) 1.54
Stability of RNA in developing Xenopus embryos and identification of a destabilizing sequence in TFIIIA messenger RNA. Development (1988) 1.51
Molecular analysis of the Escherichia coli recO gene. J Bacteriol (1989) 1.43
RNA processing by RNase III is involved in the synthesis of Escherichia coli polynucleotide phosphorylase. Mol Gen Genet (1987) 1.24
Bacteriophage lambda N gene leader RNA. RNA processing and translational initiation signals. J Biol Chem (1987) 1.18
Transcription products from the rplKAJL-rpoBC gene cluster. J Mol Biol (1987) 1.15
Posttranscriptional regulation of ribosomal protein S20 and stability of the S20 mRNA species. J Bacteriol (1987) 1.12
Q-mediated late gene transcription of bacteriophage lambda: RNA start point and RNase III processing sites in vivo. Virology (1988) 1.10
Cloned DNA sequences that determine mRNA stability of bacteriophage phi X174 in vivo are functional. Nucleic Acids Res (1985) 1.02
Retroregulation of the bacteriophage lambda int gene: limited secondary degradation of the RNase III-processed transcript. J Bacteriol (1989) 0.96
Decay of RNA in RNA processing mutants of Escherichia coli. Mol Gen Genet (1980) 0.92
Genetic alterations during colorectal-tumor development. N Engl J Med (1988) 26.82
Variable number of tandem repeat (VNTR) markers for human gene mapping. Science (1987) 25.71
An efficient recombination system for chromosome engineering in Escherichia coli. Proc Natl Acad Sci U S A (2000) 17.30
A highly efficient Escherichia coli-based chromosome engineering system adapted for recombinogenic targeting and subcloning of BAC DNA. Genomics (2001) 15.03
Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas. Science (1989) 11.53
Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans. Gene (2001) 11.09
Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients. Science (1991) 9.89
Recombineering: a powerful new tool for mouse functional genomics. Nat Rev Genet (2001) 8.35
Quantum computers. Nature (2010) 6.79
Human granulocytic ehrlichiosis in the upper Midwest United States. A new species emerging? JAMA (1994) 6.55
A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage. Nature (2000) 6.01
When is cancer pain mild, moderate or severe? Grading pain severity by its interference with function. Pain (1995) 5.97
p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53. Cell (2000) 5.64
Allelotype of colorectal carcinomas. Science (1989) 5.54
The action of tetrodotoxin on electrogenic components of squid giant axons. J Gen Physiol (1965) 5.42
AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1. Nat Genet (2000) 5.26
Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor. Science (1993) 5.22
Somatic mutations of the APC gene in colorectal tumors: mutation cluster region in the APC gene. Hum Mol Genet (1992) 5.14
Complete genome structure of the nitrogen-fixing symbiotic bacterium Mesorhizobium loti. DNA Res (2000) 4.94
Interleukin-2 receptor gamma chain: a functional component of the interleukin-4 receptor. Science (1993) 4.63
Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene. Science (1997) 4.62
The gene for familial polyposis coli maps to the long arm of chromosome 5. Science (1987) 4.48
Transient regulation of protein synthesis in Escherichia coli upon shift-up of growth temperature. J Bacteriol (1978) 4.38
High efficiency mutagenesis, repair, and engineering of chromosomal DNA using single-stranded oligonucleotides. Proc Natl Acad Sci U S A (2001) 4.30
Complete genomic sequence of the filamentous nitrogen-fixing cyanobacterium Anabaena sp. strain PCC 7120. DNA Res (2001) 4.27
A primary genetic map of markers of human chromosome 10. Genomics (1988) 4.23
Disruption of the APC gene by a retrotransposal insertion of L1 sequence in a colon cancer. Cancer Res (1992) 4.21
Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis. Nucleic Acids Res (2000) 4.11
Identification and characterization of the potential promoter regions of 1031 kinds of human genes. Genome Res (2001) 4.03
Multiple endocrine neoplasia type 1 gene maps to chromosome 11 and is lost in insulinoma. Nature (1988) 3.96
An ancient retrotransposal insertion causes Fukuyama-type congenital muscular dystrophy. Nature (1998) 3.86
Diverse transcriptional initiation revealed by fine, large-scale mapping of mRNA start sites. EMBO Rep (2001) 3.47
Results of surgical and nonsurgical treatment for small-sized hepatocellular carcinomas: a retrospective and nationwide survey in Japan. The Liver Cancer Study Group of Japan. Hepatology (2000) 3.42
Altered urinary bladder function in mice lacking the vanilloid receptor TRPV1. Nat Neurosci (2002) 3.28
Rapid confirmation of single copy lambda prophage integration by PCR. Nucleic Acids Res (1994) 3.19
Genome-wide analysis of gene expression in human hepatocellular carcinomas using cDNA microarray: identification of genes involved in viral carcinogenesis and tumor progression. Cancer Res (2001) 3.18
A high-throughput SNP typing system for genome-wide association studies. J Hum Genet (2001) 3.18
Isolation and mapping of a polymorphic DNA sequence (pTHH22) on chromosome 9 [D9S12]. Nucleic Acids Res (1988) 3.17
IL-6 is produced by osteoblasts and induces bone resorption. J Immunol (1990) 3.14
Gene organization deduced from the complete sequence of liverwort Marchantia polymorpha mitochondrial DNA. A primitive form of plant mitochondrial genome. J Mol Biol (1992) 3.11
Rapid engineering of bacterial artificial chromosomes using oligonucleotides. Genesis (2001) 3.07
Genetic analysis of a class of polymyxin resistant partial revertants of stage O sporulation mutants of Bacillus subtilis: map of the chromosome region near the origin of replication. Mol Gen Genet (1979) 3.03
Molecular detection of microscopic and submicroscopic deletions associated with Miller-Dieker syndrome. Am J Hum Genet (1988) 2.97
Mapping of mutation causing Friedreich's ataxia to human chromosome 9. Nature (1988) 2.96
A tripeptide 'anticodon' deciphers stop codons in messenger RNA. Nature (2000) 2.90
Localisation of atopy and beta subunit of high-affinity IgE receptor (Fc epsilon RI) on chromosome 11q. Lancet (1993) 2.88
Specific deficit of the ON response in visual transmission by targeted disruption of the mGluR6 gene. Cell (1995) 2.81
A mapped set of genetic markers for human chromosome 9. Genomics (1988) 2.80
Ultrastructural variation of cultured Ehrlichia chaffeensis. J Med Microbiol (1995) 2.78
Genetic mapping of autosomal dominant Charcot-Marie-Tooth disease in a large French-Acadian kindred: identification of new linked markers on chromosome 17. Am J Hum Genet (1990) 2.77
Mutation in Npps in a mouse model of ossification of the posterior longitudinal ligament of the spine. Nat Genet (1998) 2.77
The first step in the functional inactivation of the Escherichia coli polynucleotide phosphorylase messenger is a ribonuclease III processing at the 5' end. EMBO J (1987) 2.77
Experimental investigation of geologically produced antineutrinos with KamLAND. Nature (2005) 2.75
Genetic analysis of the rnc operon of Escherichia coli. J Bacteriol (1989) 2.72
Sequence of the initiation factor IF2 gene: unusual protein features and homologies with elongation factors. Proc Natl Acad Sci U S A (1984) 2.72
Correlation between the location of germ-line mutations in the APC gene and the number of colorectal polyps in familial adenomatous polyposis patients. Cancer Res (1992) 2.72
A primary genetic linkage map for human chromosome 12. Genomics (1987) 2.72
Feedback regulation of rRNA synthesis in Escherichia coli. Requirement for initiation factor IF2. J Mol Biol (1987) 2.70
Requirement of CD9 on the egg plasma membrane for fertilization. Science (2000) 2.65
Enhanced expression of a glyceraldehyde-3-phosphate dehydrogenase gene in human lung cancers. Cancer Res (1987) 2.65
Complete structure of the chloroplast genome of Arabidopsis thaliana. DNA Res (1999) 2.63
Mutations of the APC (adenomatous polyposis coli) gene. Hum Mutat (1993) 2.63
A new mutation, aly, that induces a generalized lack of lymph nodes accompanied by immunodeficiency in mice. Eur J Immunol (1994) 2.62
Impairment of suckling response, trigeminal neuronal pattern formation, and hippocampal LTD in NMDA receptor epsilon 2 subunit mutant mice. Neuron (1996) 2.62
Allelotype of breast cancer: cumulative allele losses promote tumor progression in primary breast cancer. Cancer Res (1990) 2.57
Host factor Hfq of Escherichia coli stimulates elongation of poly(A) tails by poly(A) polymerase I. Proc Natl Acad Sci U S A (2000) 2.57
New dye-labeled terminators for improved DNA sequencing patterns. Nucleic Acids Res (1997) 2.55
Extracellular ATP or ADP induce chemotaxis of cultured microglia through Gi/o-coupled P2Y receptors. J Neurosci (2001) 2.54
A radiation hybrid map of the rat genome containing 5,255 markers. Nat Genet (1999) 2.54
Association studies of 33 single nucleotide polymorphisms (SNPs) in 29 candidate genes for bronchial asthma: positive association a T924C polymorphism in the thromboxane A2 receptor gene. Hum Genet (2000) 2.50
ATR/ATM-mediated phosphorylation of human Rad17 is required for genotoxic stress responses. Nature (2001) 2.50
p53DINP1, a p53-inducible gene, regulates p53-dependent apoptosis. Mol Cell (2001) 2.47
Helium-3 emission related to volcanic activity. Science (1984) 2.43
Activation of the beta-catenin gene in primary hepatocellular carcinomas by somatic alterations involving exon 3. Cancer Res (1998) 2.42
Crystallographic and modeling studies of RNase III suggest a mechanism for double-stranded RNA cleavage. Structure (2001) 2.40
Loss of imprinting of the insulin-like growth factor II gene occurs by biallelic methylation in a core region of H19-associated CTCF-binding sites in colorectal cancer. Proc Natl Acad Sci U S A (2000) 2.38
Musashi1: an evolutionally conserved marker for CNS progenitor cells including neural stem cells. Dev Neurosci (2000) 2.36
A large scale analysis of cDNA in Arabidopsis thaliana: generation of 12,028 non-redundant expressed sequence tags from normalized and size-selected cDNA libraries. DNA Res (2000) 2.33
Genetic analysis of an inherited predisposition to colon cancer in a family with a variable number of adenomatous polyps. N Engl J Med (1990) 2.32
The human CCG1 gene, essential for progression of the G1 phase, encodes a 210-kilodalton nuclear DNA-binding protein. Mol Cell Biol (1991) 2.30
Clinical and pathological associations with allelic loss in colorectal carcinoma [corrected]. JAMA (1989) 2.29
Biochemical and genetic analysis of the effects of amylose-extender mutation in rice endosperm. Plant Physiol (2001) 2.28
Genetic approaches in mice to understand Rel/NF-kappaB and IkappaB function: transgenics and knockouts. Oncogene (1999) 2.27
Growth-suppressive effects of BPOZ and EGR2, two genes involved in the PTEN signaling pathway. Oncogene (2001) 2.25
Developmentally regulated postsynaptic localization of a metabotropic glutamate receptor in rat rod bipolar cells. Cell (1994) 2.20
Virus associated with S.M.O.N. in Japan. Lancet (1971) 2.19
Mutation analysis in the BRCA2 gene in primary breast cancers. Nat Genet (1996) 2.18
Novel proteins of the phosphotransferase system encoded within the rpoN operon of Escherichia coli. Enzyme IIANtr affects growth on organic nitrogen and the conditional lethality of an erats mutant. J Biol Chem (1995) 2.17
Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Nature (2000) 2.17
Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Nature (2000) 2.16
Genetic diagnosis of lymph-node metastasis in colorectal cancer. Lancet (1995) 2.15
A genome-wide association study identifies an association of a common variant in TERT with susceptibility to idiopathic pulmonary fibrosis. J Med Genet (2008) 2.15
Cloning, characterization and nucleotide sequences of two cDNAs encoding human pancreatic trypsinogens. Gene (1986) 2.14
A detailed genetic map of the long arm of chromosome 11. Genomics (1990) 2.11
Coherent dynamics of a flux qubit coupled to a harmonic oscillator. Nature (2004) 2.07