Published in EMBO J on March 01, 1987
Compilation of transcription regulating proteins. Nucleic Acids Res (1988) 9.71
Synergistic action of the glucocorticoid receptor with transcription factors. EMBO J (1988) 3.34
Cloning by recognition site screening of two novel GT box binding proteins: a family of Sp1 related genes. Nucleic Acids Res (1992) 2.89
A 13 bp palindrome is a functional estrogen responsive element and interacts specifically with estrogen receptor. Nucleic Acids Res (1988) 2.67
Isolation and characterization of the cDNA encoding BKLF/TEF-2, a major CACCC-box-binding protein in erythroid cells and selected other cells. Mol Cell Biol (1996) 2.31
Characterization of a complex glucocorticoid response unit in the phosphoenolpyruvate carboxykinase gene. Mol Cell Biol (1990) 2.12
The BRG1 transcriptional coregulator. Nucl Recept Signal (2008) 2.00
A common motif within the negative regulatory regions of multiple factors inhibits their transcriptional synergy. Mol Cell Biol (2000) 1.90
Cell-specific activity of a GGTCA half-palindromic oestrogen-responsive element in the chicken ovalbumin gene promoter. EMBO J (1988) 1.78
Nuclear proteins that bind the human gamma-globin gene promoter: alterations in binding produced by point mutations associated with hereditary persistence of fetal hemoglobin. Mol Cell Biol (1988) 1.63
Activation of the tyrosine aminotransferase gene is dependent on synergy between liver-specific and hormone-responsive elements. Proc Natl Acad Sci U S A (1993) 1.51
Location and characterization of two widely separated glucocorticoid response elements in the phosphoenolpyruvate carboxykinase gene. Mol Cell Biol (1988) 1.26
The role of glucocorticoid action in the pathophysiology of the Metabolic Syndrome. Nutr Metab (Lond) (2005) 1.23
Structure of human glutathione S-transferase class Mu genes. Biochem J (1991) 1.19
Two remote glucocorticoid responsive units interact cooperatively to promote glucocorticoid induction of rat tyrosine aminotransferase gene expression. Nucleic Acids Res (1989) 1.17
Expression of a human 7S K RNA gene in vivo requires a novel pol III upstream element. EMBO J (1990) 1.17
Participation of Ets transcription factors in the glucocorticoid response of the rat tyrosine aminotransferase gene. Mol Cell Biol (1994) 1.11
A progesterone responsive element maps to the far upstream steroid dependent DNase hypersensitive site of chicken lysozyme chromatin. EMBO J (1988) 1.08
Identification of a glucocorticoid-responsive element in Epstein-Barr virus. J Virol (1990) 1.05
Dual function of a nuclear factor I binding site in MMTV transcription regulation. Nucleic Acids Res (1989) 1.04
Glucocorticoids play a key role in circadian cell cycle rhythms. PLoS Biol (2007) 1.01
Paradoxical transcriptional activation of rat liver cytochrome P-450 3A1 by dexamethasone and the antiglucocorticoid pregnenolone 16 alpha-carbonitrile: analysis by transient transfection into primary monolayer cultures of adult rat hepatocytes. Proc Natl Acad Sci U S A (1992) 0.99
Isolation of a thyroid hormone-responsive gene by immunoprecipitation of thyroid hormone receptor-DNA complexes. Mol Cell Biol (1994) 0.99
Reciprocal antagonism of steroid hormones and BZLF1 in switch between Epstein-Barr virus latent and productive cycle gene expression. J Virol (1992) 0.99
The presence of both negative and positive elements in the 5'-flanking sequence of the rat Na,K-ATPase alpha 3 subunit gene are required for brain expression in transgenic mice. Nucleic Acids Res (1994) 0.97
Estrogen and progesterone receptor-binding sites on the chicken vitellogenin II gene: synergism of steroid hormone action. Mol Cell Biol (1988) 0.94
β2-Adrenergic receptor signaling in osteoblasts contributes to the catabolic effect of glucocorticoids on bone. Endocrinology (2011) 0.91
The human estrogen receptor can regulate exogenous but not endogenous vitellogenin gene promoters in a Xenopus cell line. Nucleic Acids Res (1988) 0.90
Protein kinase A activation of glucocorticoid-mediated signaling in the developing retina. Proc Natl Acad Sci U S A (1993) 0.89
Rat gene 33: analysis of its structure, messenger RNA and basal promoter activity. Nucleic Acids Res (1989) 0.88
Impaired dexamethasone-mediated induction of tryptophan 2,3-dioxygenase in heme-deficient rat hepatocytes: translational control by a hepatic eIF2alpha kinase, the heme-regulated inhibitor. J Pharmacol Exp Ther (2007) 0.88
The role of placental tryptophan catabolism. Front Immunol (2014) 0.88
Transcriptional regulation by triiodothyronine requires synergistic action of the thyroid receptor with another trans-acting factor. Mol Cell Biol (1992) 0.87
Stress-induced increase in kynurenic acid as a potential biomarker for patients with schizophrenia and distress intolerance. JAMA Psychiatry (2014) 0.86
Regulation of human renin expression in chorion cell primary cultures. Proc Natl Acad Sci U S A (1990) 0.84
Developmental control of glucocorticoid receptor transcriptional activity in embryonic retina. Proc Natl Acad Sci U S A (1993) 0.82
Effect of dipterinyl calcium pentahydrate on hepatitis B virus replication in transgenic mice. J Transl Med (2010) 0.82
Involvement of a C/EBP-like protein in the acquisition of responsiveness to glucocorticoid hormones during chick neural retina development. Mol Cell Biol (1993) 0.81
Regulation of the chicken ovalbumin gene by estrogen and corticosterone requires a novel DNA element that binds a labile protein, Chirp-1. Mol Cell Biol (1996) 0.80
GATA4 inhibits expression of the tryptophan oxygenase gene by binding to the TATA box in fetal hepatocytes. Cytotechnology (2008) 0.78
Induction of TDO2 and IDO2 in Liver by High-Fat Feeding in Mice: Discrepancies with Human Obesity. Int J Tryptophan Res (2013) 0.78
Kynurenine and uric acid levels in chronic myeloid leukemia patients. Oncoimmunology (2015) 0.77
Microbiota alteration is associated with the development of stress-induced despair behavior. Sci Rep (2017) 0.75
Prenatal kynurenine exposure in rats: age-dependent changes in NMDA receptor expression and conditioned fear responding. Psychopharmacology (Berl) (2016) 0.75
Sequencing end-labeled DNA with base-specific chemical cleavages. Methods Enzymol (1980) 287.68
Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. Mol Cell Biol (1982) 116.75
The pUC plasmids, an M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers. Gene (1982) 102.30
Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter. Nucleic Acids Res (1984) 86.56
Purification of mouse immunoglobulin heavy-chain messenger RNAs from total myeloma tumor RNA. Eur J Biochem (1980) 26.55
Biochemical transfer of single-copy eucaryotic genes using total cellular DNA as donor. Cell (1978) 19.44
Identification of two distinct regulatory regions adjacent to the human beta-interferon gene. Cell (1983) 17.60
Host-specific activation of transcription by tandem repeats from simian virus 40 and Moloney murine sarcoma virus. Proc Natl Acad Sci U S A (1982) 12.30
Steroid receptor regulated transcription of specific genes and gene networks. Annu Rev Genet (1985) 10.62
Glucocorticoids regulate expression of dihydrofolate reductase cDNA in mouse mammary tumour virus chimaeric plasmids. Nature (1981) 8.66
Characterization of DNA sequences through which cadmium and glucocorticoid hormones induce human metallothionein-IIA gene. Nature (1984) 7.57
DNA sequences bound specifically by glucocorticoid receptor in vitro render a heterologous promoter hormone responsive in vivo. Cell (1983) 7.39
Fine structure genetic analysis of a beta-globin promoter. Science (1986) 6.36
Sequence-specific binding of glucocorticoid receptor to MTV DNA at sites within and upstream of the transcribed region. Cell (1983) 6.01
The glucocorticoid receptor binds to defined nucleotide sequences near the promoter of mouse mammary tumour virus. Nature (1983) 5.76
Glucocorticoid regulation of the Ha-MuSV p21 gene conferred by sequences from mouse mammary tumor virus. Cell (1981) 4.67
Hormone-responsive expression of an endogenous proviral gene of mouse mammary tumor virus after molecular cloning and gene transfer into cultured cells. Proc Natl Acad Sci U S A (1981) 4.30
Glucocorticoid and progesterone receptors bind to the same sites in two hormonally regulated promoters. Nature (1985) 3.45
Subfragments of the large terminal repeat cause glucocorticoid-responsive expression of mouse mammary tumor virus and of an adjacent gene. Proc Natl Acad Sci U S A (1983) 3.42
Glucocorticoid responsiveness of the transcriptional enhancer of Moloney murine sarcoma virus. Cell (1986) 3.31
Sequences in the promoter region of the chicken lysozyme gene required for steroid regulation and receptor binding. Cell (1984) 3.01
Contacts between hormone receptor and DNA double helix within a glucocorticoid regulatory element of mouse mammary tumor virus. Proc Natl Acad Sci U S A (1984) 2.64
Purified glucocorticoid receptors bind selectively in vitro to a cloned DNA fragment whose transcription is regulated by glucocorticoids in vivo. Proc Natl Acad Sci U S A (1981) 2.63
Regulated expression of human growth hormone genes in mouse cells. Cell (1982) 2.58
Hormonal response region in the mouse mammary tumor virus long terminal repeat can be dissociated from the proviral promoter and has enhancer properties. Proc Natl Acad Sci U S A (1985) 2.47
Distinct sequence elements involved in the glucocorticoid regulation of the mouse mammary tumor virus promoter identified by linker scanning mutagenesis. J Mol Biol (1986) 2.30
Hormonal inducibility of rat alpha 2u globulin genes in transfected mouse cells. Nature (1981) 2.05
The first intron of the human growth hormone gene contains a binding site for glucocorticoid receptor. Proc Natl Acad Sci U S A (1985) 2.03
New cosmid vectors developed for eukaryotic DNA cloning. Gene (1984) 1.97
Purified glucocorticoid receptor-hormone complex from rat liver cytosol binds specifically to cloned mouse mammary tumor virus long terminal repeats in vitro. Proc Natl Acad Sci U S A (1982) 1.97
Rapid and quantitative recovery of DNA fragments from gels by displacement electrophoresis (isotachophoresis). Biochim Biophys Acta (1984) 1.97
Messenger RNA for hepatic tryptophan oxygenase: its partial purification, its translation in a heterologous cell-free system, and its control by glucocorticoid hormones. Proc Natl Acad Sci U S A (1973) 1.84
A 5'-flanking sequence essential for progesterone regulation of an ovalbumin fusion gene. Nature (1983) 1.70
The adaptive increase of the tryptophan peroxidase-oxidase system of liver. Science (1951) 1.63
The nucleotide sequences recognized by the glucocorticoid receptor in the rabbit uteroglobin gene region are located far upstream from the initiation of transcription. EMBO J (1984) 1.51
Transcriptional regulation of the tryptophan oxygenase gene in rat liver by glucocorticoids. J Biol Chem (1983) 1.48
RU 38486: potent antiglucocorticoid activity correlated with strong binding to the cytosolic glucocorticoid receptor followed by an impaired activation. J Steroid Biochem (1984) 1.46
Expression of a chicken lysozyme recombinant gene is regulated by progesterone and dexamethasone after microinjection into oviduct cells. Cell (1982) 1.37
Isolation and characterization of the rat tryptophan oxygenase gene. EMBO J (1982) 1.26
Androgen-regulated expression of a cloned rat prostatic c3 gene transfected into mouse mammary tumor cells. Cell (1983) 1.12
Developmental control of messenger RNA for hepatic tryptophan 2,3-dioxygenase. Proc Natl Acad Sci U S A (1977) 0.91
Phosphorylation of rat liver glucocorticoid receptor. J Biol Chem (1985) 0.89
The nuclear receptor superfamily: the second decade. Cell (1995) 24.99
CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements. Nucleic Acids Res (1987) 15.65
Conditional gene targeting in macrophages and granulocytes using LysMcre mice. Transgenic Res (1999) 12.83
Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety. Nat Genet (1999) 11.79
Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor. Nature (1995) 11.53
A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors. Cell (1996) 11.02
5'-Terminal sequences of eucaryotic mRNA can be cloned with high efficiency. Nucleic Acids Res (1981) 8.10
Steroid hormone receptors: many actors in search of a plot. Cell (1995) 7.22
CTCF is a uniquely versatile transcription regulator linked to epigenetics and disease. Trends Genet (2001) 6.80
Resetting of circadian time in peripheral tissues by glucocorticoid signaling. Science (2000) 6.55
DNA binding of the glucocorticoid receptor is not essential for survival. Cell (1998) 6.40
Cooperativity of glucocorticoid response elements located far upstream of the tyrosine aminotransferase gene. Cell (1987) 6.12
Genomic footprinting reveals cell type-specific DNA binding of ubiquitous factors. Cell (1987) 4.91
Modular structure of a chicken lysozyme silencer: involvement of an unusual thyroid hormone receptor binding site. Cell (1990) 4.13
The hormone regulatory element of mouse mammary tumour virus mediates progesterone induction. EMBO J (1986) 4.04
Exons encode functional and structural units of chicken lysozyme. Proc Natl Acad Sci U S A (1980) 4.01
Oestrogen and glucocorticoid responsive elements are closely related but distinct. Nature (1987) 3.95
Cooperativity of the glucocorticoid receptor and the CACCC-box binding factor. Nature (1988) 3.69
The micronucleus test. Mutat Res (1975) 3.53
Many transcription factors interact synergistically with steroid receptors. Science (1988) 3.49
Glucocorticoid and progesterone receptors bind to the same sites in two hormonally regulated promoters. Nature (1985) 3.45
Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation. Genes Dev (1995) 3.41
In vivo protein-DNA interactions in a glucocorticoid response element require the presence of the hormone. Nature (1987) 3.39
Synergistic action of the glucocorticoid receptor with transcription factors. EMBO J (1988) 3.34
Glucocorticoid responsiveness of the transcriptional enhancer of Moloney murine sarcoma virus. Cell (1986) 3.31
Postimplantation expression patterns indicate a role for the mouse forkhead/HNF-3 alpha, beta and gamma genes in determination of the definitive endoderm, chordamesoderm and neuroectoderm. Development (1993) 3.25
Hallux duplication, postaxial polydactyly, absence of the corpus callosum, severe mental retardation, and additional anomalies in two unrelated patients: a new syndrome. Am J Med Genet (1980) 3.18
A DNA sequence of 15 base pairs is sufficient to mediate both glucocorticoid and progesterone induction of gene expression. Proc Natl Acad Sci U S A (1987) 3.07
Sequences in the promoter region of the chicken lysozyme gene required for steroid regulation and receptor binding. Cell (1984) 3.01
A transferable silencing domain is present in the thyroid hormone receptor, in the v-erbA oncogene product and in the retinoic acid receptor. EMBO J (1992) 2.93
Mouse lysozyme M gene: isolation, characterization, and expression studies. Proc Natl Acad Sci U S A (1988) 2.84
Severe impairment of spermatogenesis in mice lacking the CREM gene. Nature (1996) 2.63
Functional analysis of alternatively spliced tyrosinase gene transcripts. EMBO J (1988) 2.60
Nucleotide sequence of cloned cDNA encoding bovine arginine vasopressin-neurophysin II precursor. Nature (1982) 2.54
Hepatocyte-specific expression of Cre recombinase. Genesis (2000) 2.52
Multiple mRNAs are generated from the chicken lysozyme gene. Cell (1981) 2.46
Magnetic vortex core reversal by excitation with short bursts of an alternating field. Nature (2006) 2.45
Regulation of retinoid signalling by receptor polarity and allosteric control of ligand binding. Nature (1994) 2.43
Tissue-specific DNaseI hypersensitive sites in the 5'-flanking sequences of the tryptophan oxygenase and the tyrosine aminotransferase genes. EMBO J (1984) 2.42
Negative protein 1, which is required for function of the chicken lysozyme gene silencer in conjunction with hormone receptors, is identical to the multivalent zinc finger repressor CTCF. Mol Cell Biol (1997) 2.37
Repression of inflammatory responses in the absence of DNA binding by the glucocorticoid receptor. EMBO J (2001) 2.34
Recent gene conversion involving bovine vasopressin and oxytocin precursor genes suggested by nucleotide sequence. Nature (1984) 2.34
The thyroid hormone receptor-beta-selective agonist GC-1 differentially affects plasma lipids and cardiac activity. Endocrinology (2000) 2.26
FHL2, a novel tissue-specific coactivator of the androgen receptor. EMBO J (2000) 2.25
Glucocorticoid hormones inhibit food-induced phase-shifting of peripheral circadian oscillators. EMBO J (2001) 2.24
Targeted mutation of the CREB gene: compensation within the CREB/ATF family of transcription factors. Proc Natl Acad Sci U S A (1994) 2.24
Phosphorylation of CREB affects its binding to high and low affinity sites: implications for cAMP induced gene transcription. EMBO J (1992) 2.23
High frequency of partial SPAST deletions in autosomal dominant hereditary spastic paraplegia. Neurology (2006) 2.09
A CamKIIalpha iCre BAC allows brain-specific gene inactivation. Genesis (2001) 2.08
Spaced training induces normal long-term memory in CREB mutant mice. Curr Biol (1997) 2.07
Activity of two different silencer elements of the chicken lysozyme gene can be compensated by enhancer elements. EMBO J (1987) 2.07
A yeast artificial chromosome covering the tyrosinase gene confers copy number-dependent expression in transgenic mice. Nature (1993) 2.06
Defective limbic system in mice lacking the tailless gene. Nature (1997) 2.05
Reporter constructs with low background activity utilizing the cat gene. Gene (1992) 2.02
Impaired fetal T cell development and perinatal lethality in mice lacking the cAMP response element binding protein. Proc Natl Acad Sci U S A (1998) 2.02
Reduction of morphine abstinence in mice with a mutation in the gene encoding CREB. Science (1996) 2.01
New cosmid vectors developed for eukaryotic DNA cloning. Gene (1984) 1.97
Characterization of the mouse HNF-4 gene and its expression during mouse embryogenesis. Mech Dev (1994) 1.96
Cloning and characterization of a second AP-2 transcription factor: AP-2 beta. Development (1995) 1.95
The glucocorticoid receptor is required for stress erythropoiesis. Genes Dev (1999) 1.92
Rescue of the albino phenotype by introduction of a functional tyrosinase gene into mice. EMBO J (1990) 1.91
Regulation of Cre recombinase activity by the synthetic steroid RU 486. Nucleic Acids Res (1996) 1.91
mRNA complexity and egg white protein mRNA content in mature and hormone-withdrawn oviduct. Cell (1977) 1.91
Mineralocorticoid receptor knockout mice: pathophysiology of Na+ metabolism. Proc Natl Acad Sci U S A (1998) 1.90
Camptothecin-induced in vivo topoisomerase I cleavages in the transcriptionally active tyrosine aminotransferase gene. Cell (1987) 1.90
Processing and quality control of DNA array hybridization data. Bioinformatics (2000) 1.86
Inactivation of the winged helix transcription factor HNF3alpha affects glucose homeostasis and islet glucagon gene expression in vivo. Genes Dev (1999) 1.86
Gene shuttling: moving of cloned DNA into and out of eukaryotic cells. Nucleic Acids Res (1982) 1.85
Multiple transcripts of the mouse tyrosinase gene are generated by alternative splicing. EMBO J (1988) 1.82
Cloning of chicken lysozyme structural gene sequences synthesized in vitro. Nucleic Acids Res (1978) 1.80
CREB is activated by UVC through a p38/HOG-1-dependent protein kinase. EMBO J (1997) 1.78
Isolation and characterization of the rat tyrosine aminotransferase gene. Proc Natl Acad Sci U S A (1984) 1.77
P-Lim, a LIM homeodomain factor, is expressed during pituitary organ and cell commitment and synergizes with Pit-1. Proc Natl Acad Sci U S A (1995) 1.77
The HNF-3 gene family of transcription factors in mice: gene structure, cDNA sequence, and mRNA distribution. Genomics (1994) 1.74
Transcriptional repression by the insulator protein CTCF involves histone deacetylases. Nucleic Acids Res (2000) 1.74
During negative regulation of the human papillomavirus-16 E6 promoter, the viral E2 protein can displace Sp1 from a proximal promoter element. Nucleic Acids Res (1992) 1.69
Lipopolysaccharide and ceramide docking to CD14 provokes ligand-specific receptor clustering in rafts. Eur J Immunol (2001) 1.68
A cyclic AMP response element mediates repression of tyrosine aminotransferase gene transcription by the tissue-specific extinguisher locus Tse-1. Cell (1990) 1.67
Multiple mRNA isoforms of the transcription activator protein CREB: generation by alternative splicing and specific expression in primary spermatocytes. EMBO J (1992) 1.66
Isolation of cDNA clones coding for rat tyrosine aminotransferase. Proc Natl Acad Sci U S A (1982) 1.65
Negative transcriptional regulation mediated by thyroid hormone response element 144 requires binding of the multivalent factor CTCF to a novel target DNA sequence. J Biol Chem (1999) 1.62