Published in J Clin Invest on September 01, 1966
The role of the kidney in the catabolism of Bence Jones proteins and immunoglobulin fragments. J Exp Med (1967) 3.06
The mechanism of intestinal uptake and transcellular transport of IgG in the neonatal rat. J Clin Invest (1972) 2.88
Catabolism of human gammaG-immunoglobulins of different heavy chain subclasses. I. Catabolism of gammaG-myeloma proteins in man. J Clin Invest (1968) 1.71
Serum IgD and IgE concentrations in immunodeficiency diseases. J Clin Invest (1975) 1.57
Immunoglobulin D in serum, body fluids and lymphoid tissues. Clin Exp Immunol (1968) 1.34
Hypogammaglobulinemia associated with accelerated catabolism of IgG secondary to its inteaction with an IgG-reactive monoclonal IgM. J Clin Invest (1971) 1.29
Human prothrombin metabolism in normal man and in hypocoagulable subjects. J Clin Invest (1969) 1.09
Metabolism of immunoglobulin E in patients with markedly elevated serum immunoglobulin E levels. J Clin Invest (1987) 1.08
Immunoglobulin D enhances the release of tumor necrosis factor-alpha, and interleukin-1 beta as well as interleukin-1 receptor antagonist from human mononuclear cells. Immunology (1996) 1.07
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IgM and IgD concentrations in the serum and secretions of children with selective IgA deficiency. Clin Exp Immunol (1983) 1.03
Serum IgD concentrations in sarcoidosis and tuberculosis. Clin Exp Immunol (1972) 1.00
Monoclonal immunoglobulins from random mutations. Br J Cancer (1968) 0.96
Younger age of presentation and extraosseous tumour in IgD myelomatosis. Br Med J (1969) 0.89
Human plasma protein N-glycosylation. Glycoconj J (2015) 0.88
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Changes in serum IgD in cigarette smokers. Clin Exp Immunol (1983) 0.78
IgD antibodies to DNP are specifically induced in ascitic fluid after intraperitoneal immunization. Immunology (1988) 0.75
Efficient trace-labelling of proteins with iodine. Nature (1958) 23.16
QUANTITATIVE DETERMINATION OF SERUM IMMUNOGLOBULINS IN ANTIBODY-AGAR PLATES. J Immunol (1965) 16.97
Gamma-globulin and acquired immunity to human malaria. Nature (1961) 13.07
Tracer experiments with I131 labeled human serum albumin: distribution and degradation studies. J Clin Invest (1953) 8.08
The theory of tracer experiments with 131I-labelled plasma proteins. Phys Med Biol (1957) 7.66
IN VIVO BEHAVIOR OF I-FIBRINOGEN. J Clin Invest (1963) 5.03
PREPARATION OF ANTISERA SPECIFIC FOR 6.6 S GAMMA-GLOBULINS, BETA 2A-GLOBULINS, GAMMA-1.-MACROGLOBULINS, AND FOR TYPE I AND II COMMON GAMMA-GLOBULIN DETERMINANTS. J Immunol (1963) 3.72
A NEW CLASS OF HUMAN IMMUNOGLOBULINS. I. A UNIQUE MYELOMA PROTEIN. J Exp Med (1965) 3.42
METABOLISM OF HUMAN GAMMA MACROGLOBULINS. J Clin Invest (1964) 3.38
A NEW CLASS OF HUMAN IMMUNOGLOBULINS. II. NORMAL SERUM IGD. J Exp Med (1965) 3.31
Clinical and experimental metabolism of normal 6.6s gamma-globulin in normal subjects and in patients with macroglobulinemia and multiple myeloma. J Lab Clin Med (1963) 2.96
Accelerated breakdown of immunoglobulin G (IgG) in myotonic dystrophy: a hereditary error of immunoglobulin catabolism. J Clin Invest (1966) 2.91
Metabolic heterogeneity of human gamma-globulin. Biochem J (1960) 2.84
FACTORS CONTROLLING SERUM GAMMA-GLOBULIN CONCENTRATION. J Exp Med (1963) 2.78
THE METABOLISM OF NORMAL PLASMA PROTEINS AND GAMMA-MYELOMA PROTEIN IN MICE BEARING PLASMA-CELL TUMORS. J Clin Invest (1961) 2.32
Comparative studies on the half-life of I 131-labeled albumins and nonradioactive human serum albumin in a case of analbuminemia. J Clin Invest (1959) 2.22
Turnover of labeled normal gamma globulin in multiple myeloma. J Clin Invest (1960) 2.09
Studies of the metabolism of I-131-labeled human transferrin. J Lab Clin Med (1963) 1.43
Analysis of the behaviour of I 131-albumin in the normal subject and nephrotic patient. Strahlentherapie (1958) 1.19
GAMMA-GLOBULIN METABOLISM. Br Med Bull (1963) 1.15
AN ANTIBODY DEFICIENCY SYNDROME. SELECTIVE IMMUNOGLOBULIN DEFICIENCY WITH REDUCED SYNTHESIS OF GAMMA AND ALPHA IMMUNOGLOBULIN POLYPEPTIDE CHAINS. Am J Med (1965) 1.13
The catabolism of plasma albumin in the rabbit: its rate and regulation. J Gen Physiol (1959) 1.12
Metabolism of infused serum albumin in the hypoproteinemia of gastro-intestinal protein loss and in analbuminemia. Trans Assoc Am Physicians (1961) 1.03
A monoclonal antibody (anti-Tac) reactive with activated and functionally mature human T cells. I. Production of anti-Tac monoclonal antibody and distribution of Tac (+) cells. J Immunol (1981) 10.92
A monoclonal antibody that appears to recognize the receptor for human T-cell growth factor; partial characterization of the receptor. Nature (1982) 9.42
Synthesis of infectious poliovirus RNA by purified T7 RNA polymerase. Proc Natl Acad Sci U S A (1986) 8.59
Role of suppressor T cells in pathogenesis of common variable hypogammaglobulinaemia. Lancet (1974) 8.13
Molecular cloning and expression of cDNAs for the human interleukin-2 receptor. Nature (1984) 7.37
A research standard for human serum immunoglobulins IgG, IgA and IgM. Bull World Health Organ (1970) 7.25
Qualitative analysis of immune function in patients with the acquired immunodeficiency syndrome. Evidence for a selective defect in soluble antigen recognition. N Engl J Med (1985) 6.46
Metabolism of immunoglobulins. Prog Allergy (1969) 5.74
Co-adjuvant effects of retinoic acid and IL-15 induce inflammatory immunity to dietary antigens. Nature (2011) 5.41
Cyclosporin A inhibits T-cell growth factor gene expression at the level of mRNA transcription. Proc Natl Acad Sci U S A (1984) 4.90
Clustered arrangement of immunoglobulin lambda constant region genes in man. Nature (1981) 4.87
Immunoglobulin D as a lymphocyte receptor. J Exp Med (1973) 4.62
Demonstration of a non-Tac peptide that binds interleukin 2: a potential participant in a multichain interleukin 2 receptor complex. Proc Natl Acad Sci U S A (1986) 4.61
The gene SCL is expressed during early hematopoiesis and encodes a differentiation-related DNA-binding motif. Proc Natl Acad Sci U S A (1989) 4.22
Human immunodeficiency virus type 1 infection in homosexual men who remain seronegative for prolonged periods. N Engl J Med (1989) 4.20
Interleukin 2 (IL-2) augments transcription of the IL-2 receptor gene. Proc Natl Acad Sci U S A (1985) 3.74
Developmental hierarchy of immunoglobulin gene rearrangements in human leukemic pre-B-cells. Proc Natl Acad Sci U S A (1981) 3.73
Primary immunodeficiencies. Report of a World Health Organization Committee. Pediatrics (1971) 3.69
Human immunoglobulin kappa light-chain genes are deleted or rearranged in lambda-producing B cells. Nature (1981) 3.64
AIDS--an immunologic reevaluation. N Engl J Med (1984) 3.53
Plasma immunoglobulin concentrations in a West African (Gambian) community and in a group of healthy British adults. Clin Exp Immunol (1968) 3.53
The acquired immunodeficiency syndrome. Ann Intern Med (1983) 3.49
Metabolic properties of IgG subclasses in man. J Clin Invest (1970) 3.48
The structure, function, and expression of interleukin-2 receptors on normal and malignant lymphocytes. Science (1986) 3.32
Radioactive single radial diffusion: a method for increasing the sensitivity of immunochemical quantification of proteins in agar gel. Bull World Health Organ (1969) 3.31
Expression of interleukin 2 receptors on activated human B cells. J Exp Med (1984) 3.27
Protein-losing enteropathy. Gastroenterology (1966) 3.21
Predominance of histocompatibility antigen HL-A8 in patients with gluten-sensitive enteropathy. J Clin Invest (1972) 3.09
The role of the kidney in the catabolism of Bence Jones proteins and immunoglobulin fragments. J Exp Med (1967) 3.06
Poliovirus host range is determined by a short amino acid sequence in neutralization antigenic site I. Science (1988) 3.03
Immunoglobulin changes in disease: quantitation on the basis of heavy polypeptide chains, IgG (gammaG), IgA (gammaA), and IgM (gammaM), and of light polypeptide chains, type K (I) and type L (II). J Clin Invest (1965) 3.00
Immunoglobulin-gene rearrangements as unique clonal markers in human lymphoid neoplasms. N Engl J Med (1983) 2.96
Immunoglobulin gene rearrangement and cell surface antigen expression in acute lymphocytic leukemias of T cell and B cell precursor origins. J Clin Invest (1983) 2.91
Accelerated breakdown of immunoglobulin G (IgG) in myotonic dystrophy: a hereditary error of immunoglobulin catabolism. J Clin Invest (1966) 2.91
The mechanism of intestinal uptake and transcellular transport of IgG in the neonatal rat. J Clin Invest (1972) 2.88
An international reference preparation for human serum immunoglobulins G, A and M: content of immunoglobulins by weight. Bull World Health Organ (1972) 2.82
IL-2-induced activation-induced cell death is inhibited in IL-15 transgenic mice. Proc Natl Acad Sci U S A (2000) 2.80
The interleukin (IL) 2 receptor beta chain is shared by IL-2 and a cytokine, provisionally designated IL-T, that stimulates T-cell proliferation and the induction of lymphokine-activated killer cells. Proc Natl Acad Sci U S A (1994) 2.79
Limited periods of gene expression in immunoglobulin-synthesizing cells. Science (1969) 2.77
Characterization of the human receptor for T-cell growth factor. Proc Natl Acad Sci U S A (1983) 2.76
Variable amplification of immunoglobulin lambda light-chain genes in human populations. Nature (1983) 2.75
Rearrangement and expression of immunoglobulin genes and expression of Tac antigen in hairy cell leukemia. Proc Natl Acad Sci U S A (1983) 2.73
Blockade of the interleukin-2 receptor by anti-Tac antibody: inhibition of human lymphocyte activation. J Immunol (1983) 2.65
The Wiskott-Aldrich syndrome. A disorder with a possible defect in antigen processing or recognition. Lancet (1968) 2.61
Quantitative changes in T helper or T suppressor/cytotoxic lymphocyte subsets that distinguish acquired immune deficiency syndrome from other immune subset disorders. Am J Med (1984) 2.60
Thalidomide for the treatment of oral aphthous ulcers in patients with human immunodeficiency virus infection. National Institute of Allergy and Infectious Diseases AIDS Clinical Trials Group. N Engl J Med (1997) 2.55
A lymphokine, provisionally designated interleukin T and produced by a human adult T-cell leukemia line, stimulates T-cell proliferation and the induction of lymphokine-activated killer cells. Proc Natl Acad Sci U S A (1994) 2.51
Ataxia-telangiectasia. Medicine (Baltimore) (1972) 2.50
Relation between sexual practices and T-cell subsets in homosexually active men. Lancet (1983) 2.46
The international spread of methicillin-resistant Staphylococcus aureus. J Hosp Infect (1987) 2.46
The mechanism of appearance of immunoglobulin A in nasal secretions in man. J Clin Invest (1967) 2.45
Accelerated course of human immunodeficiency virus infection in gay men who conceal their homosexual identity. Psychosom Med (1996) 2.40
Malignant melanoma. Effects of an early structured psychiatric intervention, coping, and affective state on recurrence and survival 6 years later. Arch Gen Psychiatry (1993) 2.38
Use of complementary therapies for arthritis among patients of rheumatologists. Ann Intern Med (1999) 2.35
The Sézary syndrome: a malignant proliferation of helper T cells. J Clin Invest (1976) 2.32
Reactive haemolysis--a distinctive form of red cell lysis. Immunology (1968) 2.32
THE METABOLISM OF NORMAL PLASMA PROTEINS AND GAMMA-MYELOMA PROTEIN IN MICE BEARING PLASMA-CELL TUMORS. J Clin Invest (1961) 2.32
Induction of IL-6 (B cell stimulatory factor-2/IFN-beta 2) production by HIV. J Immunol (1989) 2.27
Prope tolerance, perioperative campath 1H, and low-dose cyclosporin monotherapy in renal allograft recipients. Lancet (1998) 2.26
IL-15: a pleiotropic cytokine with diverse receptor/signaling pathways whose expression is controlled at multiple levels. Immunity (1996) 2.23
A humanized antibody that binds to the interleukin 2 receptor. Proc Natl Acad Sci U S A (1989) 2.23
Chromosomal translocation in a human leukemic stem-cell line disrupts the T-cell antigen receptor delta-chain diversity region and results in a previously unreported fusion transcript. Proc Natl Acad Sci U S A (1989) 2.23
The p75 peptide is the receptor for interleukin 2 expressed on large granular lymphocytes and is responsible for the interleukin 2 activation of these cells. Proc Natl Acad Sci U S A (1987) 2.22
Separation of human blood monocytes and lymphocytes on a continuous Percoll gradient. J Immunol Methods (1980) 2.21
The Golgi association of endothelial nitric oxide synthase is necessary for the efficient synthesis of nitric oxide. J Biol Chem (1995) 2.20
Regulation of interleukin 2 receptor expression: effects of phorbol diester, phospholipase C, and reexposure to lectin or antigen. J Immunol (1984) 2.20
Dynamic, yet structured: The cell membrane three decades after the Singer-Nicolson model. Proc Natl Acad Sci U S A (2003) 2.20
IgD on the surface of peripheral blood lymphocytes of the human newborn. Nat New Biol (1973) 2.19
Comparison of ipecac-induced emesis with gastric lavage in the treatment of acute salicylate ingestion. J Pediatr (1969) 2.18
Requirement for IRF-1 in the microenvironment supporting development of natural killer cells. Nature (1998) 2.17
Variables that affect assays for plasma cytokines and soluble activation markers. Clin Diagn Lab Immunol (1999) 2.15
Treatment of noninfectious intermediate and posterior uveitis with the humanized anti-Tac mAb: a phase I/II clinical trial. Proc Natl Acad Sci U S A (1999) 2.14
A recombinant immunotoxin consisting of two antibody variable domains fused to Pseudomonas exotoxin. Nature (1989) 2.13
Only high-affinity receptors for interleukin 2 mediate internalization of ligand. Proc Natl Acad Sci U S A (1986) 2.12
Infection with the human immunodeficiency virus (HIV) is associated with an in vivo increase in B lymphocyte activation and immaturity. J Immunol (1987) 2.11
CD4 percentage, CD4 number, and CD4:CD8 ratio in HIV infection: which to choose and how to use. J Acquir Immune Defic Syndr (1989) 2.10
Antibodies and immunoglobulins. II. Normal development and changes in disease. JAMA (1965) 2.10
NIH conference. T-cell lymphoproliferative syndrome associated with human T-cell leukemia/lymphoma virus. Ann Intern Med (1984) 2.10
A research standard for human serum immunoglobulin D. Bull World Health Organ (1970) 2.09
The immunoglobulins of mice. VI. Response to immunization. J Immunol (1965) 2.08
Systemic capillary leak syndrome and monoclonal IgG gammopathy; studies in a sixth patient and a review of the literature. Medicine (Baltimore) (1977) 2.07
A research standard for human serum immunoglobulin E. Bull World Health Organ (1970) 2.05
T-lymphocyte interleukin 2-dependent tyrosine protein kinase signal transduction involves the activation of p56lck. Proc Natl Acad Sci U S A (1991) 2.03
Characterization of common variable immunodeficiency: identification of a subset of patients with distinctive immunophenotypic and clinical features. Blood (1990) 2.02
Novel T-lymphocyte population in combined immunodeficiency with features of graft-versus-host disease. N Engl J Med (1989) 1.99
Suppressor cells in the regulation of the immune response. Prog Clin Immunol (1977) 1.99
Augmented T cell growth factor receptor expression in HTLV-1-infected human leukemic T cells. J Immunol (1984) 1.99
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Phase I trial of recombinant immunotoxin anti-Tac(Fv)-PE38 (LMB-2) in patients with hematologic malignancies. J Clin Oncol (2000) 1.95
The native rat olfactory cyclic nucleotide-gated channel is composed of three distinct subunits. J Neurosci (1999) 1.93
Immunological studies of homosexual men with immunodeficiency and Kaposi's sarcoma. Clin Immunol Immunopathol (1983) 1.91
Norepinephrine accelerates HIV replication via protein kinase A-dependent effects on cytokine production. J Immunol (1998) 1.90
Intestinal lymphangiectasia: a protein-losing enteropathy with hypogammaglobulinemia, lymphocytopenia and impaired homograft rejection. J Clin Invest (1967) 1.88
Early effects of HIV on CD4 lymphocytes in vivo. J Immunol (1987) 1.87
Elevated IFN-gamma and decreased IL-2 gene expression are associated with HIV infection. J Immunol (1993) 1.86
Polyclonal B-cell activators in the study of the regulation of immunoglobulin synthesis in the human system. Adv Immunol (1982) 1.85
Defective lymphocyte transformation and delayed hypersensitivity in Wiskott-Aldrich syndrome. J Immunol (1970) 1.85