Published in Nucleic Acids Res on June 25, 1983
Compilation of published signal sequences. Nucleic Acids Res (1984) 11.33
Two genes required for cell fusion during yeast conjugation: evidence for a pheromone-induced surface protein. Mol Cell Biol (1987) 7.38
Life cycle of the budding yeast Saccharomyces cerevisiae. Microbiol Rev (1988) 4.55
Nucleotide sequences of STE2 and STE3, cell type-specific sterile genes from Saccharomyces cerevisiae. EMBO J (1985) 4.37
Loss of BiP/GRP78 function blocks translocation of secretory proteins in yeast. J Cell Biol (1990) 4.19
The a-factor pheromone of Saccharomyces cerevisiae is essential for mating. Mol Cell Biol (1988) 3.62
Identification of a DNA segment that is necessary and sufficient for alpha-specific gene control in Saccharomyces cerevisiae: implications for regulation of alpha-specific and a-specific genes. Mol Cell Biol (1988) 2.79
The yeast ARD1 gene product is required for repression of cryptic mating-type information at the HML locus. Mol Cell Biol (1987) 2.30
Multiple regulation of STE2, a mating-type-specific gene of Saccharomyces cerevisiae. Mol Cell Biol (1986) 2.11
The Saccharomyces cerevisiae SPT13/GAL11 gene has both positive and negative regulatory roles in transcription. Mol Cell Biol (1989) 2.09
Alpha-factor structural gene mutations in Saccharomyces cerevisiae: effects on alpha-factor production and mating. Mol Cell Biol (1985) 1.97
Yeast STE7, STE11, and STE12 genes are required for expression of cell-type-specific genes. Mol Cell Biol (1988) 1.73
Detection of secreted peptides by using hypothesis-driven multistage mass spectrometry. Proc Natl Acad Sci U S A (2003) 1.63
The killer toxin of Kluyveromyces lactis: characterization of the toxin subunits and identification of the genes which encode them. EMBO J (1986) 1.56
Evidence from comparative genomics for a complete sexual cycle in the 'asexual' pathogenic yeast Candida glabrata. Genome Biol (2003) 1.52
The yeast SSS1 gene is essential for secretory protein translocation and encodes a conserved protein of the endoplasmic reticulum. EMBO J (1993) 1.50
Fungal lipopeptide mating pheromones: a model system for the study of protein prenylation. Microbiol Rev (1995) 1.48
Sexual pheromones and mating responses in fungi. Plant Cell (1993) 1.48
Secretion in yeast: structural features influencing the post-translational translocation of prepro-alpha-factor in vitro. EMBO J (1987) 1.47
Differential effectiveness of yeast cytochrome c oxidase subunit genes results from differences in expression not function. Mol Cell Biol (1987) 1.35
The nucleotide sequence of the yeast MEL1 gene. Nucleic Acids Res (1985) 1.28
Glycosylation and structure of the yeast MF alpha 1 alpha-factor precursor is important for efficient transport through the secretory pathway. J Bacteriol (1991) 1.26
Characterization of the yeast KEX1 gene product: a carboxypeptidase involved in processing secreted precursor proteins. Mol Cell Biol (1989) 1.25
Mutations in Saccharomyces cerevisiae that block meiotic prophase chromosome metabolism and confer cell cycle arrest at pachytene identify two new meiosis-specific genes SAE1 and SAE3. Genetics (1997) 1.25
Multiple genes coding for precursors of rhodotorucine A, a farnesyl peptide mating pheromone of the basidiomycetous yeast Rhodosporidium toruloides. Mol Cell Biol (1989) 1.21
The asexual yeast Candida glabrata maintains distinct a and alpha haploid mating types. Eukaryot Cell (2008) 1.16
Identification of sequence elements that confer cell-type-specific control of MF alpha 1 expression in Saccharomyces cerevisiae. Mol Cell Biol (1987) 1.13
Analysis of the structural genes encoding M-factor in the fission yeast Schizosaccharomyces pombe: identification of a third gene, mfm3. Mol Cell Biol (1994) 1.12
Secretion of foreign proteins from Saccharomyces cerevisiae directed by alpha-factor gene fusions. Proc Natl Acad Sci U S A (1984) 1.07
Fungal mating pheromones: choreographing the dating game. Fungal Genet Biol (2011) 1.04
Sequence-directed bends of DNA helix axis at the upstream activation sites of alpha-cell-specific genes in yeast. Nucleic Acids Res (1988) 0.99
Apidaecin multipeptide precursor structure: a putative mechanism for amplification of the insect antibacterial response. EMBO J (1993) 0.98
Transcription of alpha-specific genes in Saccharomyces cerevisiae: DNA sequence requirements for activity of the coregulator alpha 1. Mol Cell Biol (1993) 0.95
The Golgi-resident protease Kex2 acts in conjunction with Prm1 to facilitate cell fusion during yeast mating. J Cell Biol (2007) 0.95
The MF alpha 1 gene of Saccharomyces cerevisiae: genetic mapping and mutational analysis of promoter elements. Genetics (1989) 0.93
Functional characterization of an alpha-factor-like Sordaria macrospora peptide pheromone and analysis of its interaction with its cognate receptor in Saccharomyces cerevisiae. Eukaryot Cell (2005) 0.92
Regulation of alpha-factor production in Saccharomyces cerevisiae: a-factor pheromone-induced expression of the MF alpha 1 and STE13 genes. Mol Cell Biol (1989) 0.91
Quantitative assessment of enzyme specificity in vivo: P2 recognition by Kex2 protease defined in a genetic system. Proc Natl Acad Sci U S A (1998) 0.90
Synthesis, secretion and processing of alpha-factor-interferon fusion proteins in yeast. Nucleic Acids Res (1984) 0.89
A novel class of peptide pheromone precursors in ascomycetous fungi. Mol Microbiol (2010) 0.87
Mediation, by Saccharomyces cerevisiae translocation signals, of beta-lactamase transport through the Escherichia coli inner membrane and sensitive method for detection of signal sequences. J Bacteriol (1986) 0.84
Disentangling signaling gradients generated by equivalent sources. J Biol Phys (2011) 0.83
Agglutination and mating activity of the MF alpha 2-encoded alpha-factor analog in Saccharomyces cerevisiae. J Bacteriol (1986) 0.78
Biological activity of the Asn-5,Arg-7 tridecapeptide encoded by MF alpha 2 of Saccharomyces cerevisiae. J Bacteriol (1986) 0.77
Genetically engineered transvestites reveal novel mating genes in budding yeast. Genetics (2013) 0.76
Role of alpha-factor and the MF alpha 1 alpha-factor precursor in mating in yeast. Genetics (1991) 0.75
Expression and secretion of Bacillus amyloliquefaciens alpha-amylase by using the yeast pheromone alpha-factor promoter and leader sequence in Saccharomyces cerevisiae. Appl Environ Microbiol (1993) 0.75
DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci U S A (1977) 790.54
Detection of specific sequences among DNA fragments separated by gel electrophoresis. J Mol Biol (1975) 503.08
Sequencing end-labeled DNA with base-specific chemical cleavages. Methods Enzymol (1980) 287.68
A rapid alkaline extraction procedure for screening recombinant plasmid DNA. Nucleic Acids Res (1979) 214.95
Construction and characterization of new cloning vehicles. II. A multipurpose cloning system. Gene (1977) 114.87
Colony hybridization: a method for the isolation of cloned DNAs that contain a specific gene. Proc Natl Acad Sci U S A (1975) 77.46
Calcium-dependent bacteriophage DNA infection. J Mol Biol (1970) 53.43
A system for shotgun DNA sequencing. Nucleic Acids Res (1981) 52.99
Transformation of yeast. Proc Natl Acad Sci U S A (1978) 46.46
The use of thin acrylamide gels for DNA sequencing. FEBS Lett (1978) 40.52
High-frequency transformation of yeast: autonomous replication of hybrid DNA molecules. Proc Natl Acad Sci U S A (1979) 26.51
Properties of a supercoiled deoxyribonucleic acid-protein relaxation complex and strand specificity of the relaxation event. Biochemistry (1970) 26.22
Codon selection in yeast. J Biol Chem (1982) 19.13
Transformation of yeast by a replicating hybrid plasmid. Nature (1978) 16.35
Construction of plasmids carrying the cI gene of bacteriophage lambda. Proc Natl Acad Sci U S A (1976) 13.10
Reversible arrest of haploid yeast cells in the initiation of DNA synthesis by a diffusible sex factor. Exp Cell Res (1973) 10.93
Mutations affecting sexual conjugation and related processes in Saccharomyces cerevisiae. I. Isolation and phenotypic characterization of nonmating mutants. Genetics (1974) 7.34
Nucleotide sequence of cloned cDNA for bovine corticotropin-beta-lipotropin precursor. Nature (1979) 6.56
Saccharomyces cerevisiae: a diffusible sex factor. Science (1970) 6.12
Transient G1 arrest of S. cerevisiae cells of mating type alpha by a factor produced by cells of mating type a. Exp Cell Res (1974) 5.94
Mutations affecting sexual conjugation and related processes in Saccharomyces cerevisiae. II. Genetic analysis of nonmating mutants. Genetics (1974) 5.75
Structure of a yeast pheromone gene (MF alpha): a putative alpha-factor precursor contains four tandem copies of mature alpha-factor. Cell (1982) 5.64
Synchronization of haploid yeast cell cycles, a prelude to conjugation. Exp Cell Res (1973) 4.58
Yeast gene TRP5: structure, function, regulation. J Biol Chem (1982) 4.48
Yeast alpha factor is processed from a larger precursor polypeptide: the essential role of a membrane-bound dipeptidyl aminopeptidase. Cell (1983) 4.24
Synthesis of oligonucleotides on cellulose by a phosphotriester method. Nucleic Acids Res (1980) 4.00
Structural comparison of two nontandemly repeated yeast glyceraldehyde-3-phosphate dehydrogenase genes. J Biol Chem (1980) 3.35
Cloning and sequence analysis of cDNA for porcine beta-neo-endorphin/dynorphin precursor. Nature (1982) 3.09
Primary structure of the human Met- and Leu-enkephalin precursor and its mRNA. Nature (1982) 2.96
The primary structure of a glyceraldehyde-3-phosphate dehydrogenase gene from Saccharomyces cerevisiae. J Biol Chem (1979) 2.96
Isolation of beta-dihydroequilin and alpha-dihydroequilenin from the urine of pregnant mares. Nature (1956) 2.79
Cloning and sequence analysis of cDNA for bovine adrenal preproenkephalin. Nature (1982) 2.79
Molecular cloning establishes proenkephalin as precursor of enkephalin-containing peptides. Nature (1982) 2.53
Primary structural requirements for the enzymatic formation of the N-glycosidic bond in glycoproteins. Studies with alpha-lactalbumin. J Biol Chem (1978) 2.13
Characterization of a common precursor to corticotropin and beta-lipotropin: cell-free synthesis of the precursor and identification of corticotropin peptides in the molecule. Proc Natl Acad Sci U S A (1977) 1.93
Stepwise cleavage of the pro part of promelittin by dipeptidylpeptidase IV. Evidence for a new type of precursor--product conversion. Eur J Biochem (1980) 1.67
Solid phase peptide synthesis of alpha-factor, a yeast mating pheromone. Biochem Biophys Res Commun (1977) 1.66
Isolation and characterization of four related peptides exhibiting alpha factor activity from Saccharomyces cerevisiae. Eur J Biochem (1976) 1.43
Purification and amino acid sequence of mating factor from Saccharomyces cerevisiae. J Biochem (1977) 1.30
Mechanism of alpha factor biosynthesis in Saccharomyces cerevisiae. J Bacteriol (1974) 1.05
A system for shotgun DNA sequencing. Nucleic Acids Res (1981) 52.99
Supercoil sequencing: a fast and simple method for sequencing plasmid DNA. DNA (1985) 40.01
Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes. Nature (1985) 13.79
Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin. Nature (1985) 13.04
Developmental and regional expression in the rat brain and functional properties of four NMDA receptors. Neuron (1994) 11.44
Complete nucleotide sequences of the T24 human bladder carcinoma oncogene and its normal homologue. Nature (1983) 10.64
Human transforming growth factor-beta complementary DNA sequence and expression in normal and transformed cells. Nature (1985) 10.13
Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene. Science (1985) 9.12
Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95. Science (1995) 8.61
Nucleotide sequence and amplification in bacteria of structural gene for rat growth hormone. Nature (1977) 7.97
Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors. Nature (1986) 7.90
The primary structure and genetic organization of the bovine papillomavirus type 1 genome. Nature (1982) 7.24
RNA editing in brain controls a determinant of ion flow in glutamate-gated channels. Cell (1991) 6.97
Point mutation in an AMPA receptor gene rescues lethality in mice deficient in the RNA-editing enzyme ADAR2. Nature (2000) 6.67
Heteromeric NMDA receptors: molecular and functional distinction of subtypes. Science (1992) 6.49
Biological properties of human c-Ha-ras1 genes mutated at codon 12. Nature (1984) 6.21
Structure and organization of the human Ki-ras proto-oncogene and a related processed pseudogene. Nature (1983) 5.90
Human leukocyte interferon produced by E. coli is biologically active. Nature (1980) 5.86
Shuttle mutagenesis: a method of transposon mutagenesis for Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1986) 5.75
RNA editing of AMPA receptor subunit GluR-B: a base-paired intron-exon structure determines position and efficiency. Cell (1993) 5.62
Human transforming growth factor-alpha: precursor structure and expression in E. coli. Cell (1984) 5.39
Characterization of the human factor VIII gene. Nature (1984) 5.37
Cloning and expression of human tissue-type plasminogen activator cDNA in E. coli. Nature (1983) 5.27
Control of kinetic properties of AMPA receptor channels by nuclear RNA editing. Science (1994) 5.21
The distribution of 13 GABAA receptor subunit mRNAs in the rat brain. I. Telencephalon, diencephalon, mesencephalon. J Neurosci (1992) 5.02
Tripartite structure of the avian erythroblastosis virus E26 transforming gene. Nature (1984) 4.99
Oligodeoxynucleotides containing synthetic abasic sites. Model substrates for DNA polymerases and apurinic/apyrimidinic endonucleases. J Biol Chem (1987) 4.97
Interaction of RNA polymerase with promoters from bacteriophage fd. Eur J Biochem (1977) 4.94
Mutations in GPC3, a glypican gene, cause the Simpson-Golabi-Behmel overgrowth syndrome. Nat Genet (1996) 4.62
Importance of AMPA receptors for hippocampal synaptic plasticity but not for spatial learning. Science (1999) 4.56
Translocation of proteins across membranes: the signal hypothesis and beyond. Symp Soc Exp Biol (1979) 4.54
cDNA sequence of human apolipoprotein(a) is homologous to plasminogen. Nature (1987) 4.54
Divalent ion permeability of AMPA receptor channels is dominated by the edited form of a single subunit. Neuron (1992) 4.53
The structure of eight distinct cloned human leukocyte interferon cDNAs. Nature (1981) 4.50
The distribution of thirteen GABAA receptor subunit mRNAs in the rat brain. III. Embryonic and postnatal development. J Neurosci (1992) 4.45
Importance of a novel GABAA receptor subunit for benzodiazepine pharmacology. Nature (1989) 4.45
Expression of active human factor VIII from recombinant DNA clones. Nature (1984) 4.36
Relative abundance of subunit mRNAs determines gating and Ca2+ permeability of AMPA receptors in principal neurons and interneurons in rat CNS. Neuron (1995) 4.24
Activation of Ki-ras2 gene in human colon and lung carcinomas by two different point mutations. Nature (1983) 4.15
A parathyroid hormone-related protein implicated in malignant hypercalcemia: cloning and expression. Science (1987) 4.09
Identification and nucleotide sequence of a human locus homologous to the v-myc oncogene of avian myelocytomatosis virus MC29. Nature (1983) 4.06
Cloning, nucleotide sequence, and expression in Escherichia coli of the exotoxin A structural gene of Pseudomonas aeruginosa. Proc Natl Acad Sci U S A (1984) 3.98
X-linked anhidrotic (hypohidrotic) ectodermal dysplasia is caused by mutation in a novel transmembrane protein. Nat Genet (1996) 3.90
A mammalian RNA editing enzyme. Nature (1996) 3.90
Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease. Science (2000) 3.89
A family of AMPA-selective glutamate receptors. Science (1990) 3.85
Direct expression in Escherichia coli of a DNA sequence coding for human growth hormone. Nature (1979) 3.80
Cloning and expression of cDNAs for two distinct murine tumor necrosis factor receptors demonstrate one receptor is species specific. Proc Natl Acad Sci U S A (1991) 3.76
Cloning, sequencing, and secretion of Bacillus amyloliquefaciens subtilisin in Bacillus subtilis. Nucleic Acids Res (1983) 3.70
The murine transforming growth factor-beta precursor. J Biol Chem (1986) 3.67
Severe acute mountain sickness (AMS) in a permanent resident of Shimla. J Assoc Physicians India (1988) 3.59
Flip and flop: a cell-specific functional switch in glutamate-operated channels of the CNS. Science (1990) 3.53
Detection of prokaryotic signal peptidase in an Escherichia coli membrane fraction: endoproteolytic cleavage of nascent f1 pre-coat protein. Proc Natl Acad Sci U S A (1978) 3.48
A 24-base-pair DNA sequence from the MAT locus stimulates intergenic recombination in yeast. Proc Natl Acad Sci U S A (1986) 3.40
Differential signal transduction by five splice variants of the PACAP receptor. Nature (1993) 3.38
Epitope mapping of CCR5 reveals multiple conformational states and distinct but overlapping structures involved in chemokine and coreceptor function. J Biol Chem (1999) 3.35
Structural determinants of ion flow through recombinant glutamate receptor channels. Science (1991) 3.18
Membrane biogenesis: cotranslational integration of the bacteriophage f1 coat protein into an Escherichia coli membrane fraction. Proc Natl Acad Sci U S A (1979) 3.15
Construction and analysis of recombinant DNA for human chorionic somatomammotropin. Nature (1977) 3.13
Determinants of Ca2+ permeability in both TM1 and TM2 of high affinity kainate receptor channels: diversity by RNA editing. Neuron (1993) 3.08
Lutropin-choriogonadotropin receptor: an unusual member of the G protein-coupled receptor family. Science (1989) 3.03
Phenotypic suppression and misreading Saccharomyces cerevisiae. Nature (1979) 3.01
The complete sequence of the mucosal pathogen Ureaplasma urealyticum. Nature (2000) 3.01
The sequence of human serum albumin cDNA and its expression in E. coli. Nucleic Acids Res (1981) 2.97
Primary structure of the human Met- and Leu-enkephalin precursor and its mRNA. Nature (1982) 2.96
Codon-improved Cre recombinase (iCre) expression in the mouse. Genesis (2002) 2.92
Nucleotide sequence of the alkaline phosphatase gene of Escherichia coli. Gene (1986) 2.89
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Radiofrequency catheter ablation of idiopathic left ventricular tachycardia guided by a Purkinje potential. Circulation (1993) 2.71
Comparative analysis of the human type 1a and bovine type 1 papillomavirus genomes. J Virol (1983) 2.69
The primary structure of the Saccharomyces cerevisiae gene for 3-phosphoglycerate kinase. Nucleic Acids Res (1982) 2.67
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New colorimetric method for the quantitative estimation of phospholipids without acid digestion. J Lipid Res (1973) 2.66
Nucleotide sequence to the v-myc oncogene of avian retrovirus MC29. Proc Natl Acad Sci U S A (1983) 2.66
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RED2, a brain-specific member of the RNA-specific adenosine deaminase family. J Biol Chem (1996) 2.64
Functional and molecular distinction between recombinant rat GABAA receptor subtypes by Zn2+. Neuron (1990) 2.60
cDNA cloning of human liver monoamine oxidase A and B: molecular basis of differences in enzymatic properties. Proc Natl Acad Sci U S A (1988) 2.59
Molecular characterization of cryptosporidium oocysts in samples of raw surface water and wastewater. Appl Environ Microbiol (2001) 2.58
Regulated expression of human growth hormone genes in mouse cells. Cell (1982) 2.58
A standardized nomenclature for adenosine deaminases that act on RNA. RNA (1997) 2.50
Cerebellar GABAA receptor selective for a behavioural alcohol antagonist. Nature (1990) 2.50
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Expression of a human gene for interferon in yeast. Nature (1981) 2.46
Mapping and characterization of promoters in bacteriophages fd, f1 and m13. J Mol Biol (1975) 2.46
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Neurosteroids act on recombinant human GABAA receptors. Neuron (1990) 2.44