PubRank

R L Brinster

Author PubWeight™ 388.36‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice. Nature 1986 14.56
2 Germ-line transformation of mice. Annu Rev Genet 1986 8.67
3 Factors affecting the efficiency of introducing foreign DNA into mice by microinjecting eggs. Proc Natl Acad Sci U S A 1985 7.32
4 Erythroid-specific expression of human beta-globin genes in transgenic mice. EMBO J 1985 5.84
5 Regulation of metallothionein--thymidine kinase fusion plasmids injected into mouse eggs. Nature 1982 5.14
6 A 12-base-pair DNA motif that is repeated several times in metallothionein gene promoters confers metal regulation to a heterologous gene. Proc Natl Acad Sci U S A 1984 5.08
7 A single erythroid-specific DNase I super-hypersensitive site activates high levels of human beta-globin gene expression in transgenic mice. Genes Dev 1989 4.60
8 Differential regulation of metallothionein-thymidine kinase fusion genes in transgenic mice and their offspring. Cell 1982 4.60
9 An albumin enhancer located 10 kb upstream functions along with its promoter to direct efficient, liver-specific expression in transgenic mice. Genes Dev 1987 4.48
10 Dramatic growth of mice that develop from eggs microinjected with metallothionein-growth hormone fusion genes. Nature 1982 4.30
11 Somatic expression of herpes thymidine kinase in mice following injection of a fusion gene into eggs. Cell 1981 4.23
12 Overexpression of TGF alpha in transgenic mice: induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast. Cell 1990 4.05
13 Human gamma- to beta-globin gene switching in transgenic mice. Genes Dev 1990 4.04
14 Metallothionein-human GH fusion genes stimulate growth of mice. Science 1983 4.03
15 Cell lineage ablation in transgenic mice by cell-specific expression of a toxin gene. Cell 1987 4.02
16 Two 3' sequences direct adult erythroid-specific expression of human beta-globin genes in transgenic mice. Proc Natl Acad Sci U S A 1987 3.81
17 The E mu-myc transgenic mouse. A model for high-incidence spontaneous lymphoma and leukemia of early B cells. J Exp Med 1988 3.80
18 Molecular pathogenesis of hepatocellular carcinoma in hepatitis B virus transgenic mice. Cell 1989 3.60
19 Transgenic mice harboring SV40 T-antigen genes develop characteristic brain tumors. Cell 1984 3.56
20 Diversity of alpha-fetoprotein gene expression in mice is generated by a combination of separate enhancer elements. Science 1987 3.44
21 Heterologous introns can enhance expression of transgenes in mice. Proc Natl Acad Sci U S A 1991 3.34
22 Complete hepatic regeneration after somatic deletion of an albumin-plasminogen activator transgene. Cell 1991 3.31
23 Immunobiology and pathogenesis of hepatocellular injury in hepatitis B virus transgenic mice. Science 1990 3.26
24 Replacement of diseased mouse liver by hepatic cell transplantation. Science 1994 3.18
25 The effect of cells transferred into the mouse blastocyst on subsequent development. J Exp Med 1974 3.17
26 Transplantation of testis germinal cells into mouse seminiferous tubules. Int J Dev Biol 1997 3.10
27 Expression of hepatitis B virus large envelope polypeptide inhibits hepatitis B surface antigen secretion in transgenic mice. J Virol 1986 2.94
28 beta1- and alpha6-integrin are surface markers on mouse spermatogonial stem cells. Proc Natl Acad Sci U S A 1999 2.91
29 Specific expression of an elastase-human growth hormone fusion gene in pancreatic acinar cells of transgenic mice. Nature 1985 2.77
30 Tissue-specific expression of the rat pancreatic elastase I gene in transgenic mice. Cell 1984 2.59
31 A transgenic mouse model of the chronic hepatitis B surface antigen carrier state. Science 1985 2.47
32 Genetically haploid spermatids are phenotypically diploid. Nature 1989 2.45
33 Transplantation of male germ line stem cells restores fertility in infertile mice. Nat Med 2000 2.37
34 The dopamine beta-hydroxylase gene promoter directs expression of E. coli lacZ to sympathetic and other neurons in adult transgenic mice. Neuron 1991 2.37
35 Spermatid-specific expression of protamine 1 in transgenic mice. Proc Natl Acad Sci U S A 1987 2.36
36 Diabetes and tolerance in transgenic mice expressing class II MHC molecules in pancreatic beta cells. Cell 1988 2.36
37 Pancreatic neoplasia induced by SV40 T-antigen expression in acinar cells of transgenic mice. Science 1987 2.35
38 Targeted disruption of metallothionein I and II genes increases sensitivity to cadmium. Proc Natl Acad Sci U S A 1994 2.34
39 Pancreatic neoplasia induced by ras expression in acinar cells of transgenic mice. Cell 1987 2.32
40 Transgenic mice. Cell 1985 2.30
41 Spermatogonial stem cell enrichment by multiparameter selection of mouse testis cells. Proc Natl Acad Sci U S A 2000 2.30
42 Production of transgenic rabbits, sheep and pigs by microinjection. Nature 1985 2.26
43 High-level erythroid expression of human alpha-globin genes in transgenic mice. Proc Natl Acad Sci U S A 1989 2.26
44 Structural and pathological effects of synthesis of hepatitis B virus large envelope polypeptide in transgenic mice. Proc Natl Acad Sci U S A 1987 2.24
45 Pattern and kinetics of mouse donor spermatogonial stem cell colonization in recipient testes. Biol Reprod 1999 2.21
46 Abnormal sexual development in transgenic mice chronically expressing müllerian inhibiting substance. Nature 1990 2.20
47 Oncogene-induced liver neoplasia in transgenic mice. Oncogene 1989 2.20
48 The rat elastase I regulatory element is an enhancer that directs correct cell specificity and developmental onset of expression in transgenic mice. Mol Cell Biol 1987 2.12
49 SV40 enhancer and large-T antigen are instrumental in development of choroid plexus tumours in transgenic mice. Nature 1985 2.10
50 A novel MHC class II epitope expressed in thymic medulla but not cortex. Nature 1989 2.06
51 Human beta-globin locus control region: analysis of the 5' DNase I hypersensitive site HS 2 in transgenic mice. Proc Natl Acad Sci U S A 1991 2.06
52 Protamine 3'-untranslated sequences regulate temporal translational control and subcellular localization of growth hormone in spermatids of transgenic mice. Genes Dev 1989 2.06
53 Induction of mouse metallothionein-I mRNA by bacterial endotoxin is independent of metals and glucocorticoid hormones. Proc Natl Acad Sci U S A 1984 2.03
54 Reconstitution of spermatogenesis from frozen spermatogonial stem cells. Nat Med 1996 2.00
55 Expression of a microinjected immunoglobulin gene in the spleen of transgenic mice. Nature 1984 2.00
56 Culture of mouse spermatogonial stem cells. Tissue Cell 1998 1.98
57 T-cell tolerance by clonal anergy in transgenic mice with nonlymphoid expression of MHC class II I-E. Nature 1989 1.95
58 Developmental regulation of alpha-fetoprotein genes in transgenic mice. Mol Cell Biol 1985 1.94
59 Insulin-like growth factor I increases brain growth and central nervous system myelination in transgenic mice. Neuron 1993 1.93
60 Allelic exclusion and control of endogenous immunoglobulin gene rearrangement in kappa transgenic mice. Nature 1985 1.91
61 Peripheral tolerance to an islet cell-specific hemagglutinin transgene affects both CD4+ and CD8+ T cells. Eur J Immunol 1992 1.83
62 Neonatal bleeding in transgenic mice expressing urokinase-type plasminogen activator. Cell 1990 1.83
63 Transgenic mice produced by retroviral transduction of male germ-line stem cells. Proc Natl Acad Sci U S A 2001 1.83
64 Rat spermatogenesis in mouse testis. Nature 1996 1.76
65 Distal regulatory elements from the mouse metallothionein locus stimulate gene expression in transgenic mice. Mol Cell Biol 1993 1.75
66 Dwarf mice produced by genetic ablation of growth hormone-expressing cells. Genes Dev 1988 1.74
67 Germ cell transplantation from large domestic animals into mouse testes. Mol Reprod Dev 2000 1.74
68 Transgenic mice selectively lacking MHC class II (I-E) antigen expression on B cells: an in vivo approach to investigate Ia gene function. Cell 1987 1.74
69 Remodeling of the postnatal mouse testis is accompanied by dramatic changes in stem cell number and niche accessibility. Proc Natl Acad Sci U S A 2001 1.74
70 Growth enhancement of transgenic mice expressing human insulin-like growth factor I. Endocrinology 1988 1.72
71 Transgenic mice with mu and kappa genes encoding antiphosphorylcholine antibodies. J Exp Med 1986 1.72
72 Pancreatic tumor pathogenesis reflects the causative genetic lesion. Proc Natl Acad Sci U S A 1991 1.72
73 Transmission distortion and mosaicism in an unusual transgenic mouse pedigree. Cell 1984 1.71
74 Tolerance in transgenic mice expressing class II major histocompatibility complex on pancreatic acinar cells. J Exp Med 1989 1.67
75 Complete reconstitution of mouse liver with xenogeneic hepatocytes. Proc Natl Acad Sci U S A 1995 1.65
76 Introduction of genes into the germ line of animals. Harvey Lect 1988 1.64
77 Elastase I promoter directs expression of human growth hormone and SV40 T antigen genes to pancreatic acinar cells in transgenic mice. Cold Spring Harb Symp Quant Biol 1985 1.63
78 Expression of a mouse Zfy-1/lacZ transgene in the somatic cells of the embryonic gonad and germ cells of the adult testis. Development 1994 1.62
79 Inhibition of mammary gland involution is associated with transforming growth factor alpha but not c-myc-induced tumorigenesis in transgenic mice. Cancer Res 1995 1.60
80 Expression of the chicken transferrin gene in transgenic mice. Cell 1983 1.59
81 Antigen presenting function of class II MHC expressing pancreatic beta cells. Nature 1988 1.56
82 Human sickle hemoglobin in transgenic mice. Science 1990 1.54
83 Synthesis of functional human hemoglobin in transgenic mice. Science 1989 1.53
84 Computer assisted image analysis to assess colonization of recipient seminiferous tubules by spermatogonial stem cells from transgenic donor mice. Mol Reprod Dev 1999 1.53
85 Recipient preparation is critical for spermatogonial transplantation in the rat. Tissue Cell 1999 1.49
86 Genetic engineering of livestock. Science 1989 1.48
87 Metallothionein III is expressed in neurons that sequester zinc in synaptic vesicles. J Neurosci 1994 1.48
88 Tissue-specific posttranslational processing of pre-prosomatostatin encoded by a metallothionein-somatostatin fusion gene in transgenic mice. Cell 1985 1.44
89 Germ cell genotype controls cell cycle during spermatogenesis in the rat. Biol Reprod 1998 1.41
90 Primate spermatogonial stem cells colonize mouse testes. Biol Reprod 2001 1.40
91 High expression of cloned immunoglobulin kappa gene in transgenic mice is restricted to B lymphocytes. Nature 1984 1.39
92 Transgenic mice overexpressing the mouse homoeobox-containing gene Hox-1.4 exhibit abnormal gut development. Nature 1989 1.38
93 Functional analysis of spermatogonial stem cells in Steel and cryptorchid infertile mouse models. Dev Biol 2000 1.37
94 Growth allometry of the organs in giant transgenic mice. Endocrinology 1987 1.32
95 Glomerular epithelial, mesangial, and endothelial cell lines from transgenic mice. Kidney Int 1988 1.32
96 Analysis of the mouse protamine 1 promoter in transgenic mice. Proc Natl Acad Sci U S A 1993 1.31
97 Heart and bone tumors in transgenic mice. Proc Natl Acad Sci U S A 1988 1.31
98 Infertility in male transgenic mice: disruption of sperm development by HSV-tk expression in postmeiotic germ cells. Biol Reprod 1990 1.28
99 Induced chimaerism by transplanting embryonic cells into mouse blastocysts. J Exp Zool 1972 1.28
100 Expression of human growth hormone-releasing factor in transgenic mice results in increased somatic growth. Nature 1985 1.28
101 Transplantation of germ cells from rabbits and dogs into mouse testes. Biol Reprod 1999 1.27
102 Histopathology associated with elevated levels of growth hormone and insulin-like growth factor I in transgenic mice. Endocrinology 1989 1.25
103 Peripheral neuropathies, hepatocellular carcinomas and islet cell adenomas in transgenic mice. Nature 1985 1.24
104 P0 promoter directs expression of reporter and toxin genes to Schwann cells of transgenic mice. Neuron 1992 1.23
105 Somatic hypermutation of an immunoglobulin transgene in kappa transgenic mice. Nature 1987 1.23
106 Transgenic mice express the human phenylethanolamine N-methyltransferase gene in adrenal medulla and retina. Proc Natl Acad Sci U S A 1988 1.22
107 An experimental protocol for fertility preservation in prepubertal boys recently diagnosed with cancer: a report of acceptability and safety. Hum Reprod 2009 1.22
108 Transforming growth factor alpha dramatically enhances oncogene-induced carcinogenesis in transgenic mouse pancreas and liver. Mol Cell Biol 1993 1.21
109 Partial correction of murine hereditary growth disorder by germ-line incorporation of a new gene. Nature 1984 1.21
110 Xenogeneic spermatogenesis following transplantation of hamster germ cells to mouse testes. Biol Reprod 1999 1.20
111 Spermatogonial transplantation and reconstitution of donor cell spermatogenesis in recipient mice. APMIS 1998 1.19
112 Ig lambda-producing B cells do not show feedback inhibition of gene rearrangement. J Immunol 1988 1.19
113 Germline and somatic mosaicism in transgenic mice. Dev Biol 1986 1.18
114 Expression of human beta-globin genes in transgenic mice: effects of a flanking metallothionein-human growth hormone fusion gene. Mol Cell Biol 1985 1.18
115 Glomerular lesions in mice transgenic for growth hormone and insulinlike growth factor-I. I. Relationship between increased glomerular size and mesangial sclerosis. Am J Pathol 1990 1.17
116 Immortalized differentiated hepatocyte lines derived from transgenic mice harboring SV40 T-antigen genes. Exp Cell Res 1988 1.15
117 Energy metabolism in primordial germ cells of the mouse. Exp Cell Res 1977 1.13
118 Tissue-specific, inducible and functional expression of the E alpha d MHC class II gene in transgenic mice. EMBO J 1985 1.13
119 Development of germ cell transplants in mice. Biol Reprod 1998 1.12
120 Differential immunofluorescence of fertilized mouse eggs with H-2 and non-H-2 antibody. J Exp Med 1971 1.11
121 Mouse oocytes transcribe injected Xenopus 5S RNA gene. Science 1981 1.10
122 Glomerulosclerosis and renal cysts in mice transgenic for the early region of SV40. Kidney Int 1987 1.10
123 Sequences 5' of the homeobox of the Hox-1.4 gene direct tissue-specific expression of lacZ during mouse development. Development 1993 1.08
124 Dramatic pituitary hyperplasia in transgenic mice expressing a human growth hormone-releasing factor gene. Mol Endocrinol 1988 1.07
125 Clonal deletion of V beta 5+ T cells by transgenic I-E restricted to thymic medullary epithelium. J Immunol 1993 1.06
126 In vitro development of mouse oocytes. Biol Reprod 1970 1.06
127 Studies on the development of mouse embryos in vitro. IV. Interaction of energy sources. J Reprod Fertil 1965 1.06
128 Expression of mouse protamine 1 genes in transgenic mice. Ann N Y Acad Sci 1989 1.04
129 Directed expression of an oncogene to Sertoli cells in transgenic mice using mullerian inhibiting substance regulatory sequences. Mol Endocrinol 1992 1.04
130 Promoter and enhancer elements from the rat elastase I gene function independently of each other and of heterologous enhancers. Mol Cell Biol 1987 1.04
131 Expression of insulin-like growth factor I in transgenic mice with elevated levels of growth hormone is correlated with growth. Endocrinology 1988 1.03
132 Effect of iso-antibody on pre-implantation mouse embryos. Nature 1969 1.03
133 Pre-B cells in kappa-transgenic mice. Nature 1985 1.02
134 Expression of insulin-like growth factor I stimulates normal somatic growth in growth hormone-deficient transgenic mice. Endocrinology 1990 1.02
135 A pair of adjacent glucocorticoid response elements regulate expression of two mouse metallothionein genes. Proc Natl Acad Sci U S A 1997 1.02
136 Development of eight-cell mouse embryos in vitro. Exp Cell Res 1966 1.01
137 DNA rearrangement causes hepatocarcinogenesis in albumin-plasminogen activator transgenic mice. Proc Natl Acad Sci U S A 1992 1.01
138 The fate of transplanted cells in mouse blastocysts in vitro. J Exp Zool 1972 1.01
139 Use of gene transfer to increase animal growth. Cold Spring Harb Symp Quant Biol 1985 1.01
140 Relative growth of the skull and postcranium in giant transgenic mice. Genet Res 1990 1.01
141 Development of porcine ova that were centrifuged to permit visualization of pronuclei and nuclei. Biol Reprod 1985 1.00
142 Immortalized retinal neurons derived from SV40 T-antigen-induced tumors in transgenic mice. Neuron 1990 1.00
143 Insertion, expression and physiology of growth-regulating genes in ruminants. J Reprod Fertil Suppl 1990 1.00
144 Active chloride transport in the isolated rabbit oviduct. Am J Physiol 1971 0.99
145 Expression from the transferrin gene promoter in transgenic mice. Mol Cell Biol 1989 0.99
146 Leuprolide, a gonadotropin-releasing hormone agonist, enhances colonization after spermatogonial transplantation into mouse testes. Tissue Cell 1998 0.98
147 Lactate dehydrogenase activity in the preimplanted mouse embryo. Biochim Biophys Acta 1965 0.98
148 Expression of NGF in sympathetic neurons leads to excessive axon outgrowth from ganglia but decreased terminal innervation within tissues. Neuron 1993 0.98
149 Integration, expression and germ-line transmission of growth-related genes in pigs. J Reprod Fertil Suppl 1990 0.97
150 Translation of globin messenger RNA by the mouse ovum. Nature 1980 0.97
151 Retrovirus-mediated gene delivery into male germ line stem cells. FEBS Lett 2000 0.96
152 Expression of human HPRT in the central nervous system of transgenic mice. Nature 1985 0.96
153 Synthesis of tubulin and actin during the preimplantation development of the mouse. Exp Cell Res 1978 0.96
154 Expression and performance in transgenic pigs. J Reprod Fertil Suppl 1990 0.95
155 A chicken transferrin gene in transgenic mice escapes X-chromosome inactivation. Science 1987 0.95
156 Ultrastructural observations of spermatogenesis in mice resulting from transplantation of mouse spermatogonia. J Androl 1997 0.95
157 A recessive defect in lymphocyte or granulocyte function caused by an integrated transgene. Am J Pathol 1992 0.94
158 Simian virus 40 (SV40)-transgenic mice that develop tumors are specifically tolerant to SV40 T antigen. J Exp Med 1987 0.92
159 Estrogen regulation of the avian transferrin gene in transgenic mice. Mol Cell Biol 1986 0.92
160 Leukemia inhibitory factor induces neurotransmitter switching in transgenic mice. Proc Natl Acad Sci U S A 1994 0.91
161 Poly(A) and synthesis of polyadenylated RNA in the preimplantation mouse embryo. Dev Biol 1978 0.91
162 Selective expression of class II E alpha d gene in transgenic mice. J Immunol 1989 0.90
163 Hypomyelinating peripheral neuropathies and schwannomas in transgenic mice expressing SV40 T-antigen. J Neurosci 1994 0.89
164 Some neuronal cell populations express human dopamine beta-hydroxylase-lacZ transgenes transiently during embryonic development. Neuron 1991 0.89
165 Regulation of fat and muscle development by transforming growth factor alpha in transgenic mice and in cultured cells. Cell Growth Differ 1993 0.89
166 Actin and tubulin synthesis in murine blastocyst outgrowths. Exp Cell Res 1978 0.88
167 In vitro culture of mammalian embryos. J Anim Sci 1968 0.88
168 Enrichment and transplantation of spermatogonial stem cells. Int J Androl 2000 0.88
169 Protein degradation in the mouse blastocyst. J Biol Chem 1979 0.88
170 Gonadotroph-specific expression of metallothionein fusion genes in pituitaries of transgenic mice. Science 1986 0.87
171 Expression of creatine kinase isoenzyme during oogenesis and embryogenesis in the mouse. Dev Biol 1983 0.87
172 Visualization and ablation of phenylethanolamine N-methyltransferase producing cells in transgenic mice. Transgenic Res 1994 0.87
173 Hexokinase activity in the preimplantation mouse embryo. Enzymologia 1968 0.86
174 A C/EBP-binding site in the transferrin promoter is essential for expression in the liver but not the brain of transgenic mice. Mol Cell Biol 1993 0.86
175 Effect of the GnRH-agonist leuprolide on colonization of recipient testes by donor spermatogonial stem cells after transplantation in mice. Tissue Cell 2001 0.86
176 Malic dehydrogenase activity in the preimplantation mouse embryo. Exp Cell Res 1966 0.86
177 Cloning of a gamma 2b gene encoding anti-Pseudomonas aeruginosa H chains and its introduction into the germ line of mice. J Immunol 1988 0.85
178 Tumorigenesis in transgenic mice by a nuclear transport-defective SV40 large T-antigen gene. Virology 1987 0.85
179 Oxidation of pyruvate and glucose by oocytes of the mouse and rhesus monkey. J Reprod Fertil 1971 0.85
180 c-myc-induced lymphomagenesis in transgenic mice and the role of the Pvt-1 locus in lymphoid neoplasia. Curr Top Microbiol Immunol 1986 0.85
181 Expression of human metallothionein-III in transgenic mice. Neurochem Int 1995 0.85
182 No simple solution for making transgenic mice. Cell 1989 0.85
183 Ultrastructural observations of spermatogenesis following transplantation of rat testis cells into mouse seminiferous tubules. J Androl 1997 0.84
184 Oncogene expression in retinal horizontal cells of transgenic mice results in a cascade of neurodegeneration. Neuron 1993 0.84
185 Cell-specific expression from the human dopamine beta-hydroxylase promoter in transgenic mice is controlled via a combination of positive and negative regulatory elements. J Neurosci 1994 0.84
186 Immunohistochemical analysis of human growth hormone-releasing hormone gene expression in transgenic mice. Endocrinology 1989 0.84
187 Developmental study of SV40 large T antigen expression in transgenic mice with choroid plexus neoplasia. Oncogene Res 1988 0.84
188 Carbon dioxide production from glucose by the preimplantation mouse embryo. Exp Cell Res 1967 0.84
189 Protein content of the mouse embryo during the first five days of development. J Reprod Fertil 1967 0.83
190 Metallothionein-vasopressin fusion gene expression in transgenic mice. Nephrogenic diabetes insipidus and brain transcripts localized to magnocellular neurons. J Biol Chem 1989 0.83
191 Role of growth hormone in regulating T-dependent immune events in aged, nude, and transgenic rodents. J Neurosci Res 1987 0.83
192 Requirements for blastocyst development in vitro. J Anim Sci 1979 0.83
193 Expression of mouse IgA by transgenic mice, pigs and sheep. Eur J Immunol 1991 0.83
194 Effects of alpha-amanitin on RNA synthesis by mouse embryos in culture. J Exp Zool 1978 0.83
195 Protein degradation during preimplantation development of the mouse. J Reprod Fertil 1981 0.83
196 Transgenic progeny inherit tissue-specific expression of rat elastase I genes. DNA 1986 0.82
197 Glucose 6-phosphate-dehydrogenase activity in the preimplantation mouse embryo. Biochem J 1966 0.82
198 Progress on gene transfer in farm animals. Vet Immunol Immunopathol 1987 0.82
199 Changes in membrane potential during mouse egg development. Dev Biol 1973 0.82
200 Tissue distribution and molecular heterogeneity of human growth hormone-releasing factor in the transgenic mouse. Endocrinology 1990 0.81
201 Glycogen content of preimplantation mouse embryos. Anat Rec 1966 0.81
202 Stimulation of growth hormone synthesis by glucose in islets of Langerhans isolated from transgenic mice. J Biol Chem 1986 0.81
203 Influence of reduced glucose levels on the in vitro hatching, attachment, and trophoblast outgrowth of the mouse blastocyst. Dev Biol 1976 0.81
204 The myc oncogene and lymphoid neoplasia: from translocations to transgenic mice. Haematol Blood Transfus 1987 0.81
205 Tissue-specific expression of pancreatic genes in transgenic mice. Ann N Y Acad Sci 1986 0.81
206 Ectopic expression of metallothionein-III causes pancreatic acinar cell necrosis in transgenic mice. Toxicol Appl Pharmacol 1998 0.80
207 Trans membrane potential of the rabbit blastocyst trophoblast. Exp Cell Res 1969 0.80
208 SV40 T-antigen is a histocompatibility antigen of SV40-transgenic mice. Immunogenetics 1988 0.80
209 Development of germ cell transplants: morphometric and ultrastructural studies. Tissue Cell 1999 0.80
210 Effect of glutathione on the development of two-cell mouse embryos in vitro. J Reprod Fertil 1968 0.80
211 Clonal anergy of I-E-tolerant T cells in transgenic mice with pancreatic expression of MHC class II I-E. Cold Spring Harb Symp Quant Biol 1989 0.80
212 Transferrin- and albumin-directed expression of growth-related peptides in transgenic sheep. J Anim Sci 1991 0.80
213 Somatostatin is targeted to the regulated secretory pathway of gonadotrophs in transgenic mice expressing a metallothionein-somatostatin gene. J Biol Chem 1986 0.80
214 Protein metabolism in preimplanted mouse ova. Dev Biol 1976 0.80
215 Rabbit alpha-globin messenger RNA translation by the mouse ovum. J Embryol Exp Morphol 1983 0.80
216 Lactate dehydrogenase isozymes in the early mouse embryo. Exp Cell Res 1967 0.80
217 In-vitro fertilization of mouse ova within the explanted fallopian tube. J Reprod Fertil 1965 0.80
218 Embryo development. J Anim Sci 1974 0.79
219 Peripheral tolerance in transgenic mice: tolerance to class II MHC and non-MHC transgene antigens. Immunol Rev 1991 0.79
220 The sensitivity of one-cell mouse embryos to pyruvate and lactate. Exp Cell Res 1973 0.79
221 Influence of ions, inhibitors and anoxia on transtrophoblast potential of rabbit blastocyst. Exp Cell Res 1970 0.79
222 High plasma levels of immunoreactive somatostatin in transgenic mice expressing a metallothionein-somatostatin fusion gene. Trans Assoc Am Physicians 1984 0.78
223 Translation and stability of ovalbumin messenger RNA injected into growing oocytes and fertilized ova of mice. J Embryol Exp Morphol 1984 0.78
224 Effects of cordycepin on macromolecular synthesis and development in the preimplantation mouse embryo. Exp Cell Res 1977 0.78
225 Delay of early B-lymphocyte development by gamma 2b immunoglobulin transgene: effect on differentiation-specific molecules. Dev Immunol 1990 0.78
226 Effect of oxygen concentration on the development of two-cell mouse embryos. Nature 1968 0.78
227 Genetic engineering of mammalian embryos. J Anim Sci 1986 0.78
228 Carbon dioxide production from pyruvate and glucose by bovine oocytes. Exp Cell Res 1973 0.78
229 Transgenic mice containing growth hormone fusion genes. Philos Trans R Soc Lond B Biol Sci 1984 0.78
230 Histologic characterization of hepatic carcinogenesis in transgenic mice expressing SV40 T-antigens. Vet Pathol 1993 0.78
231 Expression of an avian protamine in transgenic mice disrupts chromatin structure in spermatozoa. Biol Reprod 1995 0.78
232 Odontogenic tumors in mice carrying albumin-myc and albumin-rats transgenes. Calcif Tissue Int 1992 0.77
233 Lactate dehydrogenase isozymes in mouse blastocyst cultures. Exp Cell Res 1968 0.77
234 Radioactive carbon dioxide production from pyruvate and lactate by the preimplantation rabbit embryo. Exp Cell Res 1969 0.77
235 Lactic dehydrogenase activity in preimplantation rat embryo. Nature 1967 0.77
236 Alteration of neurotransmitter phenotype in noradrenergic neurons of transgenic mice. Mol Endocrinol 1992 0.77
237 Pulmonary carcinogenesis in transgenic mice. Exp Lung Res 1991 0.77
238 Expression of human or bovine growth hormone gene with a mouse metallothionein-1 promoter in transgenic swine alters the secretion of porcine growth hormone and insulin-like growth factor-I. J Endocrinol 1989 0.76
239 The uptake of hexoses by pre-implantation mouse embryos in vitro. J Reprod Fertil 1968 0.76
240 Dramatic growth of mice that develop from eggs microinjected with metallothionein-growth hormone fusion genes. 1982. Biotechnology 1992 0.76
241 Incorporation of carbon from glucose and pyruvate into the preimplantation mouse embryo. Exp Cell Res 1969 0.76
242 Embryo culture, stem cells and experimental modification of the embryonic genome. An interview with Professor Ralph Brinster.. Interview by Juan Aréchaga. Int J Dev Biol 1998 0.76
243 Production of transgenic sheep with growth-regulating genes. Mol Reprod Dev 1989 0.75
244 Elevation of 1,2-diacylglycerol in ras-transformed neonatal liver and pancreas of transgenic mice. Oncogene 1989 0.75
245 Antisense oligodeoxynucleoside methylphosphonate inhibition of mouse c-myc p65 protein expression in E mu-c-myc transgenic mice. Nucleic Acids Symp Ser 1991 0.75
246 Leucine uptake and incorporation at three stages of mouse oocyte maturation. Exp Cell Res 1974 0.75
247 Activity of mitochondrial enzymes in mouse embryos. J Reprod Fertil 1973 0.75
248 Activity of 6-phosphogluconate dehydrogenase in the preimplantation mouse and rabbit embryo. Experientia 1971 0.75
249 Effects of alpha-amanitin on the development of mouse ova in culture. J Reprod Fertil 1977 0.75
250 Culture of two-cell rabbit embryos to morulae. J Reprod Fertil 1970 0.75
251 De novo pyrimidine nucleotide synthesis in the preimplantation mouse embryo. Exp Cell Res 1981 0.75
252 Stability of rabbit globin and its messenger RNA in the mouse ovum. Exp Cell Res 1982 0.75
253 Lactate dehydrogenase activity in the preimplantation rabbit embryo. Biochim Biophys Acta 1967 0.75
254 Blastocyst development of mouse pre-implantation embryos in the rabbit Fallopian tube. J Reprod Fertil 1969 0.75
255 Glucose 6-phosphate dehydrogenase activity in the early rbbit and mouse embryo. Biochem Genet 1970 0.75
256 Multiple sequences regulate human beta-globin gene expression in transgenic mice. Prog Clin Biol Res 1987 0.75
257 Antigen presentation in MHC class II transgenic mice: stimulation versus tolerization. Immunol Rev 1990 0.75
258 Secretion of protein by the fertilized mouse ovum. Exp Cell Res 1981 0.75
259 Lactate dehydrogenase isozymes in the preimplantation rabbit embryo. Biochem Genet 1973 0.75
260 Uptake and incorporation of amino acids by the preimplantation mouse embryo. J Reprod Fertil 1971 0.75
261 Expression of a metallothionein-vasopressin fusion gene in transgenic mice produces hypervasopressinemia and manifestations of nephrogenic diabetes insipidus. Trans Assoc Am Physicians 1988 0.75
262 Tolerance to class II MHC in transgenic mice. Semin Immunol 1989 0.75
263 Effect of copper on the preimplantation mouse embryo. Nature 1972 0.75
264 Atrial natriuretic peptide synthesis in atrial tumors of transgenic mice. Am J Physiol 1992 0.75
265 I-E transgenic mice: a model system to dissect the regulation and function of MHC class II genes in vivo. Immunol Res 1990 0.75
266 Parental glucose phosphate isomerase activity in three-day mouse embryos. Biochem Genet 1973 0.75
267 Synthesis and secretion of ovalbumin by mouse-growing oocytes following microinjection of chick ovalbumin mRNA. Exp Cell Res 1983 0.75
268 Effects of a nonsteroidal antifertility agent (U-11100A) on pregnancy in mice. J Reprod Fertil 1969 0.75
269 Carbon dioxide production from lactate and pyruvate by the preimplantation mouse embryo. Exp Cell Res 1967 0.75
270 The regulation of alpha-foetoprotein minigene expression in the germline of mice. J Embryol Exp Morphol 1986 0.75
271 DNase I super-hypersensitive sites direct high level erythroid expression of human alpha-, beta- and beta s- globin genes in transgenic mice. Prog Clin Biol Res 1989 0.75
272 Lactate dehydrogenase activity in the oocytes of mammals. J Reprod Fertil 1968 0.75
273 Somatic expression of herpes thymidine kinase in mice following injection of a fusion gene into eggs. 1982. Biotechnology 1992 0.75
274 Gene transplants into germ cells. Hosp Pract (Off Ed) 1987 0.75
275 Effect of bovine growth hormone gene expression, sex and age on plasma gonadotropins, estrone and testosterone in prepuberal pigs. Domest Anim Endocrinol 1991 0.75
276 Participation of teratocarcinoma cells in mouse embryo development. Cancer Res 1976 0.75
277 Targeted expression of cloned genes in transgenic mice. Prog Brain Res 1987 0.75
278 Changes in protein synthesis following fertilization of the mouse ovum. J Exp Zool 1980 0.75