Published in Cell on January 01, 1982
Simian virus 40 large T antigen is phosphorylated at multiple sites clustered in two separate regions. J Virol (1982) 3.18
Initiation of simian virus 40 DNA replication in vitro. J Virol (1983) 2.88
Topography of simian virus 40 A protein-DNA complexes: arrangement of protein bound to the origin of replication. J Virol (1983) 2.79
Regulation of SV40 DNA replication by phosphorylation of T antigen. EMBO J (1987) 2.17
Consensus topography in the ATP binding site of the simian virus 40 and polyomavirus large tumor antigens. Proc Natl Acad Sci U S A (1987) 2.15
Monoclonal antibodies against simian virus 40 nuclear large T tumour antigen: epitope mapping, papova virus cross-reaction and cell surface staining. EMBO J (1984) 2.08
DNA-binding activity of simian virus 40 large T antigen correlates with a distinct phosphorylation state. J Virol (1984) 2.01
Genetic and biochemical analysis of transformation-competent, replication-defective simian virus 40 large T antigen mutants. J Virol (1985) 1.92
DNA-binding properties of simian virus 40 T-antigen mutants defective in viral DNA replication. Mol Cell Biol (1983) 1.76
Different forms of simian virus 40 large tumor antigen varying in their affinities for DNA. J Virol (1982) 1.72
DNA-binding region of the simian virus 40 tumor antigen. J Virol (1986) 1.62
Monomers through trimers of large tumor antigen bind in region I and monomers through tetramers bind in region II of simian virus 40 origin of replication DNA as stable structures in solution. Proc Natl Acad Sci U S A (1985) 1.59
Polyomavirus and simian virus 40 large T antigens bind to common DNA sequences. J Virol (1984) 1.56
Acylated simian virus 40 large T-antigen: a new subclass associated with a detergent-resistant lamina of the plasma membrane. EMBO J (1983) 1.55
Phosphorylation downregulates the DNA-binding activity of simian virus 40 T antigen. J Virol (1986) 1.50
DNA binding activity of polyoma virus large tumor antigen. Proc Natl Acad Sci U S A (1984) 1.47
Subclasses of simian virus 40 large T antigen: differential binding of two subclasses of T antigen from productively infected cells to viral and cellular DNA. EMBO J (1982) 1.46
Improved localization of phosphorylation sites in simian virus 40 large T antigen. J Virol (1983) 1.42
Simian virus 40 tumor antigen: isolation of the origin-specific DNA-binding domain. J Virol (1983) 1.42
Human adenovirus early region 4 open reading frame 1 genes encode growth-transforming proteins that may be distantly related to dUTP pyrophosphatase enzymes. J Virol (1997) 1.39
Specific in vitro adenylylation of the simian virus 40 large tumor antigen. Proc Natl Acad Sci U S A (1984) 1.38
Mutational analysis of simian virus 40 large T antigen DNA binding sites. EMBO J (1984) 1.31
Two separable functional domains of simian virus 40 large T antigen: carboxyl-terminal region of simian virus 40 large T antigen is required for efficient capsid protein synthesis. J Virol (1985) 1.31
DNA polymerase alpha from the nuclear matrix of cells infected with simian virus 40. Nucleic Acids Res (1982) 1.27
Assembly of T-antigen double hexamers on the simian virus 40 core origin requires only a subset of the available binding sites. Mol Cell Biol (1998) 1.25
Characterization of human papillomavirus type 11 E1 and E2 proteins expressed in insect cells. J Virol (1993) 1.17
trans-dominant defective mutants of simian virus 40 T antigen. J Virol (1987) 1.14
Purification and functional properties of simian virus 40 large and small T antigens overproduced in insect cells. J Virol (1988) 1.14
Role of single-stranded DNA binding activity of T antigen in simian virus 40 DNA replication. J Virol (2001) 1.13
Replication and transformation functions of in vitro-generated simian virus 40 large T antigen mutants. J Virol (1986) 1.08
Structure and biochemical functions of four simian virus 40 truncated large-T antigens. J Virol (1982) 1.07
Activities of polyomavirus large-T-antigen proteins expressed by mutant genes. J Virol (1984) 1.04
Replicative functions of minute virus of mice NS1 protein are regulated in vitro by phosphorylation through protein kinase C. J Virol (1998) 1.04
Structural prerequisites of simian virus 40 large T antigen for the maintenance of cell transformation. EMBO J (1985) 1.03
Linker insertion mutants of simian virus 40 large T antigen that show trans-dominant interference with wild-type large T antigen map to multiple sites within the T-antigen gene. J Virol (1989) 1.01
The kinase activity of SV40 large T antigen is mediated by a cellular kinase. EMBO J (1986) 1.01
Characterization of simian virus 40 large T antigen by using different monoclonal antibodies: T-p53 complexes are preferentially ATPase active and adenylylated. J Virol (1988) 1.00
Protein kinase activities in immune complexes of simian virus 40 large T-antigen and transformation-associated cellular p53 protein. Mol Cell Biol (1984) 0.99
Association of simian virus 40 T antigen with the nuclear matrix of infected and transformed monkey cells. Mol Cell Biol (1984) 0.96
The abnormal location of cytoplasmic SV40 large T is not caused by failure to bind to DNA or to p53. EMBO J (1985) 0.96
Self-assembly of simian virus 40 large T antigen oligomers by divalent cations. J Virol (1983) 0.95
Oligomerization and origin DNA-binding activity of simian virus 40 large T antigen. J Virol (1987) 0.93
Free and viral chromosome-bound simian virus 40 T antigen: changes in reactivity of specific antigenic determinants during lytic infection. J Virol (1986) 0.93
Stoichiometry of large T antigen and pp53 in complexes isolated from simian virus 40-transformed rat cells. J Virol (1983) 0.90
Oligomerization of simian virus 40 large T antigen is not necessarily repressed by temperature-sensitive A gene lesions. J Virol (1984) 0.89
Activation of ATPase activity of simian virus 40 large T antigen by the covalent affinity analog of ATP, fluorosulfonylbenzoyl 5'-adenosine. J Virol (1990) 0.88
A kinase activity associated with simian virus 40 large T antigen phosphorylates upstream binding factor (UBF) and promotes formation of a stable initiation complex between UBF and SL1. Mol Cell Biol (1999) 0.88
Immunoprecipitation of some forms of simian virus 40 large-T antigen by antibodies to synthetic peptides. J Virol (1984) 0.86
Functional implications of oligomerization of simian virus 40 large T antigen during lytic virus infection. J Virol (1985) 0.85
The origin DNA-binding and single-stranded DNA-binding domains of simian virus 40 large T antigen are distinct. J Virol (1998) 0.84
Specific mutation of a regulatory site within the ATP-binding region of simian virus 40 large T antigen. J Virol (1991) 0.83
Biochemical properties of the 145,000-dalton super-T antigen from simian virus 40-transformed BALB/c 3T3 clone 20 cells. J Virol (1983) 0.82
A subclass of polyomavirus middle tumor antigen binds to DNA cellulose. J Virol (1986) 0.82
Polyomavirus large T antigen binds cooperatively to its multiple binding sites in the viral origin of DNA replication. J Virol (1998) 0.80
Mechanisms of interference with simian virus 40 (SV40) DNA replication by trans-dominant mutants of SV40 large T antigen. J Virol (1992) 0.80
Characterization of am404, an amber mutation in the simian virus 40 T antigen gene. J Virol (1983) 0.80
Expression of 100,000-Mr simian virus 40 (SV40) tumor antigen in mouse fibroblasts transfected with replication-defective SV40 genomes. J Virol (1986) 0.80
Preferential binding of simian virus 40 T-antigen dimers to origin region I. J Virol (1989) 0.79
MC29 virus-coded protein occurs as monomers and dimers in transformed cells. J Virol (1985) 0.79
Dimers and complexes with p53 are the prevalent oligomeric forms of a transforming nonkaryophilic T antigen of simian virus 40. J Virol (1987) 0.77
Topoisomerase activity is associated with purified SV40 T antigen. Nucleic Acids Res (1993) 0.77
Simian virus 40 large T antigen oligomers: analysis of electrophoresis in the absence of detergent. J Virol (1985) 0.75
SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene. Cell (1988) 12.69
Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor. Genes Dev (1994) 8.92
Association of BRCA1 with Rad51 in mitotic and meiotic cells. Cell (1997) 8.28
Functional interactions of the retinoblastoma protein with mammalian D-type cyclins. Cell (1993) 7.19
Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300. Cell (1998) 6.73
Identification of cellular proteins that can interact specifically with the T/E1A-binding region of the retinoblastoma gene product. Cell (1991) 6.55
The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element. Cell (1989) 6.43
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Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage. Cell (1997) 5.92
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T antigen repression of SV40 early transcription from two promoters. Cell (1981) 4.83
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