Published in J Biol Chem on February 25, 1984
Ca2+-dependent hydrophobic-interaction chromatography. Isolation of a novel Ca2+-binding protein and protein kinase C from bovine brain. Biochem J (1984) 1.45
Ca2+-binding proteins from bovine brain including a potent inhibitor of protein kinase C. Biochem J (1985) 1.26
Purification and properties of a 23 kDa Ca2(+)-binding protein from Drosophila melanogaster. Biochem J (1990) 0.83
Purification, immunological and biochemical characterization of rat 28 kDa cholecalcin (cholecalciferol-induced calcium-binding proteins). Identity between renal and cerebellar cholecalcins. Biochem J (1985) 0.75
Solution structure of a calmodulin-target peptide complex by multidimensional NMR. Science (1992) 6.16
Calmodulin. Annu Rev Biochem (1980) 4.22
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Identification of the NH2-terminal blocking group of calcineurin B as myristic acid. FEBS Lett (1982) 3.42
Solution structure of calcium-free calmodulin. Nat Struct Biol (1995) 3.36
Calcineurin: a calcium- and calmodulin-binding protein of the nervous system. Proc Natl Acad Sci U S A (1979) 3.33
Solution structure of Ca(2+)-calmodulin reveals flexible hand-like properties of its domains. Nat Struct Biol (2001) 3.18
Inhibition of T cell signaling by immunophilin-ligand complexes correlates with loss of calcineurin phosphatase activity. Biochemistry (1992) 3.05
Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A. Proc Natl Acad Sci U S A (1992) 2.98
Purification of cyclic 3',5'-nucleotide phosphodiesterase inhibitory protein by affinity chromatography on activator protein coupled to Sepharose. Biochemistry (1978) 2.89
Purification and characterization of smooth muscle myosin light chain kinase. J Biol Chem (1981) 2.84
Discovery of a Ca2+- and calmodulin-dependent protein phosphatase: probable identity with calcineurin (CaM-BP80). FEBS Lett (1982) 2.75
Changes in D(--)-beta-hydroxybutyric dehydrogenase activity during brain maturation in the rat. J Biol Chem (1967) 2.55
Conformational transition accompanying the binding of Ca2+ to the protein activator of 3',5'-cyclic adenosine monophosphate phosphodiesterase. Biochemistry (1977) 2.34
Phosphorylation of smooth muscle myosin light chain kinase by the catalytic subunit of adenosine 3': 5'-monophosphate-dependent protein kinase. J Biol Chem (1978) 2.33
Calcineurin: from structure to function. Curr Top Cell Regul (2000) 2.10
Positive cooperative binding of calcium to bovine brain calmodulin. Biochemistry (1980) 2.08
Dual calcium ion regulation of calcineurin by calmodulin and calcineurin B. Biochemistry (1994) 2.02
Effects of cations on affinity of calmodulin for calcium: ordered binding of calcium ions allows the specific activation of calmodulin-stimulated enzymes. Biochemistry (1981) 1.87
Functional domain structure of calcineurin A: mapping by limited proteolysis. Biochemistry (1989) 1.86
Activation of calcineurin by limited proteolysis. Proc Natl Acad Sci U S A (1983) 1.85
Calmodulin. Adv Cyclic Nucleotide Protein Phosphorylation Res (1984) 1.65
Ca2+ binding and conformational change in two series of point mutations to the individual Ca(2+)-binding sites of calmodulin. J Biol Chem (1992) 1.64
Inhibition of neutrophil chemokinesis on vitronectin by inhibitors of calcineurin. Science (1992) 1.53
Cloning of human calcineurin A: evidence for two isozymes and identification of a polyproline structural domain. Proc Natl Acad Sci U S A (1989) 1.52
Superoxide dismutase protects calcineurin from inactivation. Nature (1996) 1.32
Subunit structure and catalytic properties of bovine brain Ca2+-dependent cyclic nucleotide phosphodiesterase. Biochemistry (1979) 1.29
The processive degradation of individual polyribonucleotide chains. II. Micrococcus lysodeikticus polynucleotide phosphorylase. J Biol Chem (1968) 1.26
Isolation and characterization of bovine brain calcineurin: a calmodulin-stimulated protein phosphatase. Methods Enzymol (1983) 1.23
Calmodulin binding by calcineurin. Ligand-induced renaturation of protein immobilized on nitrocellulose. J Biol Chem (1987) 1.22
Purification of smooth muscle myosin light-chain kinase. Methods Enzymol (1982) 1.21
Interaction of calmodulin with myosin light chain kinase and cAMP-dependent protein kinase in bovine brain. J Biol Chem (1981) 1.21
Characterization of [3H](+/-)carazolol binding to beta-adrenergic receptors. Application to study of beta-adrenergic receptor subtypes in canine ventricular myocardium and lung. Circ Res (1981) 1.19
Identification, characterization, and functional correlation of calmodulin-dependent protein phosphatase in sperm. J Cell Biol (1988) 1.19
Calcium modulation of inositol 1,4,5-trisphosphate-induced calcium release from neuroblastoma x glioma hybrid (NG108-15) microsomes. J Biol Chem (1986) 1.17
The effects of deletions in the central helix of calmodulin on enzyme activation and peptide binding. J Biol Chem (1989) 1.16
Phosphorylase kinase from rabbit skeletal muscle: identification of the calmodulin-binding subunits. Eur J Biochem (1980) 1.16
A convenient method for the preparation of primer-dependent polynucleotide phosphorylase from Micrococcus lysodeikticus. Biochem Biophys Res Commun (1967) 1.14
Agonist and antagonist properties of calmodulin fragments. J Biol Chem (1984) 1.13
Ultrastructural immunocytochemical localization of calmodulin in cultured cells. J Histochem Cytochem (1983) 1.13
Isotope-edited multidimensional NMR of calcineurin B in the presence of the non-deuterated detergent CHAPS. J Biomol NMR (1993) 1.11
The role of alpha-lactalbumin in lactose synthetase. Biochem Biophys Res Commun (1970) 1.10
Anticholinergic effects of disopyramide and quinidine on guinea pig myocardium. Mediation by direct muscarinic receptor blockade. Circ Res (1980) 1.10
The structure of the B subunit of calcineurin. Eur J Biochem (1984) 1.09
Calmodulin activates the isolated catalytic unit of brain adenylate cyclase. J Biol Chem (1981) 1.08
The proteolytic conversion of polynucleotide phosphorylase to a primer-dependent form. J Biol Chem (1969) 1.06
Characterization of the intrinsic cAMP-dependent protein kinase activity and endogenous substrates in highly purified cardiac sarcolemmal vesicles. J Biol Chem (1982) 1.04
Interaction of 125I-labeled Ca2+-dependent regulator protein with cyclic nucleotide phosphodiesterase and its inhibitory protein. J Biol Chem (1978) 1.04
Low affinity Ca2+-binding sites of calcineurin B mediate conformational changes in calcineurin A. Biochemistry (2000) 1.04
Exocytosis induction in Paramecium tetraurelia cells by exogenous phosphoprotein phosphatase in vivo and in vitro: possible involvement of calcineurin in exocytotic membrane fusion. J Cell Biol (1987) 1.03
Activation of phosphorylase kinase from rabbit skeletal muscle by calmodulin and troponin. FEBS Lett (1979) 1.03
Calcineurin A alpha (PPP3CA), calcineurin A beta (PPP3CB) and calcineurin B (PPP3R1) are located on human chromosomes 4, 10q21-->q22 and 2p16-->p15 respectively. Cytogenet Cell Genet (1996) 0.99
Serine/threonine phosphatases in the nervous system. Curr Opin Neurobiol (1991) 0.98
Genetically engineered calmodulins differentially activate target enzymes. J Biol Chem (1986) 0.98
1H, 13C, 15N nuclear magnetic resonance backbone assignments and secondary structure of human calcineurin B. Biochemistry (1994) 0.97
Reversible and irreversible activation of cyclic nucleotide phosphodiesterase: separation of the regulatory and catalytic domains by limited proteolysis. Adv Cyclic Nucleotide Protein Phosphorylation Res (1984) 0.97
Specific perturbation by Ca2+ of tyrosyl residue 138 of calmodulin. J Biol Chem (1979) 0.94
Identification and quantification of calcium-binding proteins in squid axoplasm. J Neurosci (1988) 0.94
Solution structure of calmodulin and its complex with a myosin light chain kinase fragment. Cell Calcium (1992) 0.94
Polynucleotide phosphorylase of Micrococcus luteus (Micrococcus lysodeikticus). The effect of sulfhydryl compounds on the ability to catalyze the polymerization reaction. J Biol Chem (1968) 0.93
The interaction of -lactalbumin and the A protein of lactose synthetase. J Biol Chem (1972) 0.92
Reversible polymerization of histidine ammonia lyase. The role of sulfhydryl groups in the activity and polymeric state of the enzyme. J Biol Chem (1970) 0.90
Rabbit FKBP-59/HBI does not inhibit calcineurin activity in vitro. Biochem Biophys Res Commun (1994) 0.89
Regulation of the calcium signal by calmodulin. Ciba Found Symp (1986) 0.88
Characterization of the lanthanide ion-binding properties of calcineurin-B using laser-induced luminescence spectroscopy. Biochemistry (1994) 0.87
Spurious protein activators of Bordetella pertussis adenylate cyclase. Eur J Biochem (1981) 0.86
Isolation and sequence of a cDNA clone for human calcineurin B, the Ca2+-binding subunit of the Ca2+/calmodulin-stimulated protein phosphatase. DNA (1989) 0.86
Domain II of calmodulin is involved in activation of calcineurin. FEBS Lett (1988) 0.86
Heteronuclear 3D NMR and isotopic labeling of calmodulin. Towards the complete assignment of the 1H NMR spectrum. Biochem Pharmacol (1990) 0.86
Molecular cloning and characterization of the genes encoding the two subunits of Drosophila melanogaster calcineurin. J Biol Chem (1992) 0.86
Conformation-dependent nitration of the protein activator of cyclic adenosine 3',5'-monophosphate phosphodiesterase. Biochemistry (1978) 0.85
Calcium-induced sensitization of the central helix of calmodulin to proteolysis. Biochemistry (1991) 0.85
Isolation of a cysteine-peptide at the active site of histidine ammonia-lyase. J Biol Chem (1972) 0.84
Calcium ion dependent covalent modification of calmodulin with norchlorpromazine isothiocyanate. Biochemistry (1983) 0.84
Cardiac autonomic receptors. Recent concepts from radiolabeled ligand-binding studies. Circ Res (1982) 0.82
Metal activation of histidine ammonia-lyase. Metal ion-sulfhydryl group relationship. J Biol Chem (1972) 0.82
Concerted role of calmodulin and calcineurin in calcium regulation. Ann N Y Acad Sci (1980) 0.81
Enrichment, solubilization, and partial characterization of digitonin-solubilized muscarinic receptors derived from canine ventricular myocardium. Circ Res (1983) 0.81
Calcium control of muscle phosphorylase kinase through the combined action of calmodulin and troponin. Ann N Y Acad Sci (1980) 0.81
Phenothiazine-binding and attachment sites of CAPP1-calmodulin. Biochemistry (1989) 0.80
Characterization of a high-affinity monoclonal antibody to calcineurin whose epitope defines a new structural domain of calcineurin A. Eur J Biochem (1989) 0.80
Affinity selection of chemically modified proteins: role of lysyl residues in the binding of calmodulin to calcineurin. Biochemistry (1987) 0.80
The regulation of muscle phosphorylase kinase by calcium ions, calmodulin and troponin-C. Cell Calcium (1981) 0.79
Selective affinity chromatography with calmodulin fragments coupled to sepharose. J Biol Chem (1985) 0.79
The phosphorylation of calmodulin and calmodulin fragments by kinase fractions from bovine brain. Biochim Biophys Acta (1988) 0.79
4-Nitro-L-histidine as a substrate for histidine ammonia-lyase: the role of beta-hydrogen acidity in the rate-limiting step. Biochem Biophys Res Commun (1979) 0.78
Histidine ammonia-lyase. The use of 4-fluorohistidine in identification of the rate-determining step. J Biol Chem (1975) 0.78
There is communication between all four Ca(2+)-bindings sites of calcineurin B. Biochemistry (2001) 0.78
Large scale preparation of calmodulin. Prep Biochem (1988) 0.78
A deoxyadenylate kinase activity associated with polynucleotide phosphorylase from Micrococcus luteus. Nucleic Acids Res (1976) 0.78
The effect of thyroid on protein synthesis in brain and other organs. Res Publ Assoc Res Nerv Ment Dis (1966) 0.78
Stereospecific irreversible inhibition of histidine ammonia-lyase by L-cysteine. Biochemistry (1974) 0.76
Multiple forms of calcineurin, a brain isozyme of the calmodulin-stimulated protein phosphatase. Adv Second Messenger Phosphoprotein Res (1990) 0.76
NMR identification of calcineurin B residues affected by binding of a calcineurin A peptide. FEBS Lett (1995) 0.76
Calcineurin: a member of a family of calmodulin-stimulated protein phosphatases. Proc Soc Exp Biol Med (1984) 0.76
Activation of Bordetella pertussis adenylate cyclase by the carboxyl-terminal tryptic fragment of calmodulin. Biochemistry (1986) 0.76