Published in J Biol Chem on June 10, 1981
A 12-base-pair DNA motif that is repeated several times in metallothionein gene promoters confers metal regulation to a heterologous gene. Proc Natl Acad Sci U S A (1984) 5.08
Dramatic growth of mice that develop from eggs microinjected with metallothionein-growth hormone fusion genes. Nature (1982) 4.30
Somatic expression of herpes thymidine kinase in mice following injection of a fusion gene into eggs. Cell (1981) 4.23
Characterization and use of the Drosophila metallothionein promoter in cultured Drosophila melanogaster cells. Nucleic Acids Res (1988) 3.66
Building a metal-responsive promoter with synthetic regulatory elements. Mol Cell Biol (1985) 3.39
Regulation, linkage, and sequence of mouse metallothionein I and II genes. Mol Cell Biol (1984) 3.25
Regulation of a metallothionein-growth hormone hybrid gene in bovine papilloma virus. Proc Natl Acad Sci U S A (1983) 3.06
Changes in liver-specific compared to common gene transcription during primary culture of mouse hepatocytes. Mol Cell Biol (1983) 3.01
An RNA polymerase I enhancer in Saccharomyces cerevisiae. Mol Cell Biol (1986) 2.85
Neoplastic transformation induced by an activated lymphocyte-specific protein tyrosine kinase (pp56lck). Mol Cell Biol (1988) 2.80
Duplicated heavy metal control sequences of the mouse metallothionein-I gene. Proc Natl Acad Sci U S A (1984) 2.69
Heavy metal toxicity and the environment. EXS (2012) 2.28
Mammalian SWI-SNF complexes contribute to activation of the hsp70 gene. Mol Cell Biol (2000) 2.10
Induction of mouse metallothionein-I mRNA by bacterial endotoxin is independent of metals and glucocorticoid hormones. Proc Natl Acad Sci U S A (1984) 2.03
Metal-regulated transcription in eukaryotes. Nucleic Acids Res (1992) 1.98
Replication-defective chimeric helper proviruses and factors affecting generation of competent virus: expression of Moloney murine leukemia virus structural genes via the metallothionein promoter. Mol Cell Biol (1987) 1.94
Targeting and germ-line transmission of a null mutation at the metallothionein I and II loci in mouse. Proc Natl Acad Sci U S A (1993) 1.88
Calmodulin is required for cell-cycle progression during G1 and mitosis. EMBO J (1989) 1.73
An analysis of the rate of metallothionein mRNA poly(A)-shortening using RNA blot hybridization. Nucleic Acids Res (1985) 1.67
Lines of BPV-transformed murine cells that constitutively express influenza virus hemagglutinin. EMBO J (1985) 1.66
Introduction of genes into the germ line of animals. Harvey Lect (1988) 1.64
Expression and regulation of a human metallothionein gene carried on an autonomously replicating shuttle vector. Proc Natl Acad Sci U S A (1983) 1.54
SV40 T antigen and the exocytotic pathway. EMBO J (1985) 1.52
Coordinate regulation of stromelysin and collagenase genes determined with cDNA probes. Proc Natl Acad Sci U S A (1987) 1.52
The exocrine protein trypsinogen is targeted into the secretory granules of an endocrine cell line: studies by gene transfer. J Cell Biol (1985) 1.50
Structure, organization, and regulation of human metallothionein IF gene: differential and cell-type-specific expression in response to heavy metals and glucocorticoids. Mol Cell Biol (1986) 1.49
High blood pressure in transgenic mice carrying the rat angiotensinogen gene. EMBO J (1992) 1.48
Characterization of isoprotein patterns in tissue extracts and isolated samples of metallothioneins by reverse-phase high-pressure liquid chromatography. Biochem J (1983) 1.38
Coordinate regulation of mouse metallothionein I and II genes by heavy metals and glucocorticoids. Mol Cell Biol (1985) 1.38
Isolation and structural organization of the Neurospora crassa copper metallothionein gene. EMBO J (1985) 1.37
Induction of metallothionein-I mRNA in cultured cells by heavy metals and iodoacetate: evidence for gratuitous inducers. Mol Cell Biol (1984) 1.37
Transcriptional induction of the mouse metallothionein-I gene in hydrogen peroxide-treated Hepa cells involves a composite major late transcription factor/antioxidant response element and metal response promoter elements. Nucleic Acids Res (1994) 1.35
A DNA segment controlling metal-regulated expression of the Drosophila melanogaster metallothionein gene Mtn. Mol Cell Biol (1987) 1.34
Expression of the herpes simplex virus 1 alpha transinducing factor (VP16) does not induce reactivation of latent virus or prevent the establishment of latency in mice. J Virol (1991) 1.31
Dynamic regulation of copper uptake and detoxification genes in Saccharomyces cerevisiae. Mol Cell Biol (1998) 1.23
Human metallothionein genes are clustered on chromosome 16. Proc Natl Acad Sci U S A (1984) 1.23
Interleukin 1 regulates human metallothionein gene expression. Mol Cell Biol (1985) 1.23
Zinc dependent binding of a liver nuclear factor to metal response element MRE-a of the mouse metallothionein-I gene and variant sequences. Nucleic Acids Res (1990) 1.19
Generation of transgenic mice with elevated blood pressure by introduction of the rat renin and angiotensinogen genes. Proc Natl Acad Sci U S A (1990) 1.18
Cell cycle regulation of glucocorticoid receptor function. EMBO J (1992) 1.17
Induction of metallothionein mRNA in rat liver and kidney after copper chloride injection. Biochem J (1985) 1.12
High-frequency deletional rearrangement of immunoglobulin kappa gene segments introduced into a pre-B-cell line. Proc Natl Acad Sci U S A (1987) 1.11
Mosaic expression of a tyrosinase fusion gene in albino mice yields a heritable striped coat color pattern in transgenic homozygotes. Proc Natl Acad Sci U S A (1991) 1.09
Regulation of the rat metallothionein-I gene by sodium butyrate. Nucleic Acids Res (1986) 1.09
Development of a radioimmunoassay for rat liver metallothionein-I and its application to the analysis of rat plasma and kidneys. Biochem J (1983) 1.06
Promoter and enhancer elements from the rat elastase I gene function independently of each other and of heterologous enhancers. Mol Cell Biol (1987) 1.04
A pair of adjacent glucocorticoid response elements regulate expression of two mouse metallothionein genes. Proc Natl Acad Sci U S A (1997) 1.02
Copper-induced ferroportin-1 expression in J774 macrophages is associated with increased iron efflux. Proc Natl Acad Sci U S A (2004) 1.01
Metallothionein mRNA expression in mice homozygous for chromosomal deletions around the albino locus. Proc Natl Acad Sci U S A (1988) 1.00
Induction of reactivation of herpes simplex virus in murine sensory ganglia in vivo by cadmium. J Virol (1993) 0.99
Induction of metallothionein I by phenolic antioxidants requires metal-activated transcription factor 1 (MTF-1) and zinc. Biochem J (2004) 0.98
A primer vector system that allows temperature dependent gene amplification and expression in mammalian cells: regulation of the influenza virus NS1 gene expression. Nucleic Acids Res (1985) 0.98
Metallothionein--aspects related to copper and zinc metabolism. J Inherit Metab Dis (1983) 0.95
Amplification and expression of human alpha-globin genes in Chinese hamster ovary cells. Mol Cell Biol (1984) 0.94
The human metallothionein gene family: structure and expression. Environ Health Perspect (1984) 0.94
Molecular studies of ceruloplasmin deficiency in Wilson's disease. J Clin Invest (1987) 0.94
Unstable expression and amplification of a transfected oncogene in confluent and subconfluent cells. Mol Cell Biol (1985) 0.92
Construction of cell lines that regulate by temperature the amplification and expression of influenza virus non-structural protein genes. EMBO J (1986) 0.92
A mutant mouse (tx) with increased hepatic metallothionein stability and accumulation. Biochem J (1993) 0.91
Transfection of neonatal rat Schwann cells with SV-40 large T antigen gene under control of the metallothionein promoter. J Cell Biol (1987) 0.91
Regulation of gene amplification and expression in cells that constitutively express a temperature sensitive SV40 T-antigen. Nucleic Acids Res (1985) 0.91
Metal-specific posttranscriptional control of human metallothionein genes. Mol Cell Biol (1989) 0.91
Glutathione-mediated transfer of Cu(I) into phytochelatins. Biochem J (1995) 0.90
Metallothionein and brain inflammation. J Biol Inorg Chem (2011) 0.90
A potential role for alterations of zinc and zinc transport proteins in the progression of Alzheimer's disease. J Alzheimers Dis (2009) 0.90
Testis-specific expression of a metallothionein I-driven transgene correlates with undermethylation of the locus in testicular DNA. Proc Natl Acad Sci U S A (1993) 0.90
Metallothionein messenger RNA regulation in the mottled mouse and Menkes kinky hair syndrome. J Clin Invest (1987) 0.90
Simultaneous induction of Pb-metallothionein-like protein and Zn-thionein in the liver of rats given lead acetate. Biochem J (1986) 0.90
Alternative inducers of the rat metallothionein I gene cause distinct changes in chromatin structure in the 5' region of the gene. Mol Cell Biol (1986) 0.89
Mouse hepatic metallothionein-I gene cleavage by micrococcal nuclease is enhanced after induction by cadmium. Nucleic Acids Res (1983) 0.88
Zinc rapidly induces a metal response element-binding factor. Proc Natl Acad Sci U S A (1992) 0.88
Tissue-specific expression from a compound TATA-dependent and TATA-independent promoter. Mol Cell Biol (1990) 0.88
The bulk chromatin structure of a murine transgene does not vary with its transcriptional or DNA methylation status. Mol Cell Biol (1995) 0.87
Molecular cloning of chicken metallothionein. Deduction of the complete amino acid sequence and analysis of expression using cloned cDNA. Nucleic Acids Res (1988) 0.87
The zinc-sensing mechanism of mouse MTF-1 involves linker peptides between the zinc fingers. Mol Cell Biol (2006) 0.87
Acute treatment of mice with cadmium salts results in amplification of the metallothionein-1 gene in liver. Nucleic Acids Res (1985) 0.85
Regulation of metallothionein gene expression by 1 alpha,25-dihydroxyvitamin D3 in cultured cells and in mice. Proc Natl Acad Sci U S A (1987) 0.84
Metal-inducible pathology in the liver, pancreas, and kidney of transgenic mice expressing SV40 early region genes. Am J Pathol (1989) 0.83
Uptake and binding of cadmium and mercury to metallothionein in rat hepatocyte primary cultures. Biochem J (1982) 0.81
Interaction of cadmium and oestradiol-17 beta on metallothionein and vitellogenin synthesis in rainbow trout (Oncorhynchus mykiss). Biochem J (1995) 0.81
Properties of cadmium-binding proteins in rat testes. Characteristics unlike metallothionein. Biochem J (1985) 0.80
Interactions of the zinc-regulated factor (ZiRF1) with the mouse metallothionein Ia promoter. Biochem J (1997) 0.80
Isolation and partial characterization of the low-molecular-mass zinc/cadmium-binding protein from the testes of the patas monkey (Erythrocebus patas). Distinction from metallothionein. Biochem J (1988) 0.79
Augmentation of dexamethasone induction of rat liver metallothionein by zinc. Biochem J (1984) 0.79
Cd2+-induced synthesis of metallothionein in HeLa cells. Biochem J (1985) 0.79
Roles of synthesis and degradation in the regulation of metallothionein accretion in a chicken macrophage-cell line. Biochem J (1990) 0.79
Use of metallothioneins as biomarkers for environmental quality assessment in the Gulf of Gabès (Tunisia). Environ Monit Assess (2011) 0.78
Heavy metal-induced metallothionein expression is regulated by specific protein phosphatase 2A complexes. J Biol Chem (2014) 0.78
Metallothionein mRNA and protein induction by cadmium in peripheral-blood leucocytes. Biochem J (1989) 0.78
Zinc inhibits the reproductive toxicity of Zearalenone in immortalized murine ovarian granular KK-1 cells. Sci Rep (2015) 0.77
Mechanism of cadmium ion substitution in mammalian zinc metallothionein and metallothionein alpha domain: kinetic and structural studies. Inorg Chem (2010) 0.77
Metallothioneins and brain injury: What transgenic mice tell us. Environ Health Prev Med (2004) 0.77
Mutations in humans and animals which affect copper metabolism. J Inherit Metab Dis (1983) 0.77
Effects of dietary copper supplementation of rats on the occurrence of metallothionein-I in liver and its secretion into blood, bile and urine. Biochem J (1986) 0.77
Decreased carbonic anhydrase III levels in the liver of the mouse mutant 'toxic milk' (tx) due to copper accumulation. Biochem J (1997) 0.75
Transient response of amplified metallothionein genes in CHO cells to induction by alpha interferon. Mol Cell Biol (1987) 0.75
Characterization of a polypurine/polypyrimidine sequence upstream of the mouse metallothionein-I gene. Nucleic Acids Res (1998) 0.75
The effects of acute waterborne exposure to sublethal concentrations of molybdenum on the stress response in rainbow trout, Oncorhynchus mykiss. PLoS One (2015) 0.75
The Role of Nuclear Factor-E2-Related Factor 1 in the Oxidative Stress Response in MC3T3-E1 Osteoblastic Cells. Endocrinol Metab (Seoul) (2016) 0.75
Regulation of growth hormone-releasing hormone gene expression and biosynthesis. Yale J Biol Med (1990) 0.75
The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice. Nature (1986) 14.56
Magnesium precipitation of ribonucleoprotein complexes. Expedient techniques for the isolation of undergraded polysomes and messenger ribonucleic acid. Biochemistry (1974) 11.67
Transcriptional regulation of the ovalbumin and conalbumin genes by steroid hormones in chick oviduct. J Biol Chem (1979) 9.48
Germ-line transformation of mice. Annu Rev Genet (1986) 8.67
Factors affecting the efficiency of introducing foreign DNA into mice by microinjecting eggs. Proc Natl Acad Sci U S A (1985) 7.32
Leptin-regulated endocannabinoids are involved in maintaining food intake. Nature (2001) 6.36
Erythroid-specific expression of human beta-globin genes in transgenic mice. EMBO J (1985) 5.84
Introns increase transcriptional efficiency in transgenic mice. Proc Natl Acad Sci U S A (1988) 5.18
Regulation of metallothionein--thymidine kinase fusion plasmids injected into mouse eggs. Nature (1982) 5.14
A 12-base-pair DNA motif that is repeated several times in metallothionein gene promoters confers metal regulation to a heterologous gene. Proc Natl Acad Sci U S A (1984) 5.08
Structure of mouse metallothionein-I gene and its mRNA. Nature (1981) 5.06
Late endosomal membranes rich in lysobisphosphatidic acid regulate cholesterol transport. Nat Cell Biol (1999) 4.76
A single erythroid-specific DNase I super-hypersensitive site activates high levels of human beta-globin gene expression in transgenic mice. Genes Dev (1989) 4.60
Differential regulation of metallothionein-thymidine kinase fusion genes in transgenic mice and their offspring. Cell (1982) 4.60
The mouse metallothionein-I gene is transcriptionally regulated by cadmium following transfection into human or mouse cells. Cell (1982) 4.55
An albumin enhancer located 10 kb upstream functions along with its promoter to direct efficient, liver-specific expression in transgenic mice. Genes Dev (1987) 4.48
Ovalbumin: a secreted protein without a transient hydrophobic leader sequence. Proc Natl Acad Sci U S A (1978) 4.46
Dramatic growth of mice that develop from eggs microinjected with metallothionein-growth hormone fusion genes. Nature (1982) 4.30
Somatic expression of herpes thymidine kinase in mice following injection of a fusion gene into eggs. Cell (1981) 4.23
Overexpression of TGF alpha in transgenic mice: induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast. Cell (1990) 4.05
Human gamma- to beta-globin gene switching in transgenic mice. Genes Dev (1990) 4.04
Metallothionein-human GH fusion genes stimulate growth of mice. Science (1983) 4.03
Cell lineage ablation in transgenic mice by cell-specific expression of a toxin gene. Cell (1987) 4.02
Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y. Nature (1996) 3.99
Two 3' sequences direct adult erythroid-specific expression of human beta-globin genes in transgenic mice. Proc Natl Acad Sci U S A (1987) 3.81
DNA methylation controls the inducibility of the mouse metallothionein-I gene lymphoid cells. Cell (1981) 3.67
Molecular pathogenesis of hepatocellular carcinoma in hepatitis B virus transgenic mice. Cell (1989) 3.60
Transgenic mice harboring SV40 T-antigen genes develop characteristic brain tumors. Cell (1984) 3.56
Building a metal-responsive promoter with synthetic regulatory elements. Mol Cell Biol (1985) 3.39
Response of melanocortin-4 receptor-deficient mice to anorectic and orexigenic peptides. Nat Genet (1999) 3.37
Complete hepatic regeneration after somatic deletion of an albumin-plasminogen activator transgene. Cell (1991) 3.31
A practical approach for quantitating specific mRNAs by solution hybridization. Anal Biochem (1983) 3.30
Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y. Science (1996) 3.28
Immunobiology and pathogenesis of hepatocellular injury in hepatitis B virus transgenic mice. Science (1990) 3.26
Regulation, linkage, and sequence of mouse metallothionein I and II genes. Mol Cell Biol (1984) 3.25
Replacement of diseased mouse liver by hepatic cell transplantation. Science (1994) 3.18
Isolation and characterization of the mouse metallothionein-I gene. Proc Natl Acad Sci U S A (1980) 3.17
Ovalbumin messenger ribonucleic acid translation. Comparable rates of polypeptide initiation and elongation on ovalbumin and globin messenger ribonucleic acid in a rabbit reticulocyte lysate. J Biol Chem (1973) 3.13
Amplification of the metallothionein-I gene in cadmium-resistant mouse cells. Proc Natl Acad Sci U S A (1981) 3.11
Identification and isolation of ovalbumin-synthesizing polysomes. I. Specific binding of 125 I-anti-ovalbumin to polysomes. J Biol Chem (1972) 2.96
Expression of hepatitis B virus large envelope polypeptide inhibits hepatitis B surface antigen secretion in transgenic mice. J Virol (1986) 2.94
Dopamine-deficient mice are severely hypoactive, adipsic, and aphagic. Cell (1995) 2.89
Correlation of procollagen mRNA levels in normal and transformed chick embryo fibroblasts with different rates of procollagen synthesis. Biochemistry (1978) 2.85
Noradrenaline is essential for mouse fetal development. Nature (1995) 2.84
Specific expression of an elastase-human growth hormone fusion gene in pancreatic acinar cells of transgenic mice. Nature (1985) 2.77
Regulation of protein synthesis in chick oviduct. I. Independent regulation of ovalbumin, conalbumin, ovomucoid, and lysozyme induction. J Biol Chem (1972) 2.76
Quantitation of parameters that determine the rate of ovalbumin synthesis. Cell (1975) 2.74
Modulation of ovalbumin synthesis by estradiol-17 beta and actinomycin D as studied in explants of chick oviduct in culture. J Biol Chem (1971) 2.73
Identification of multiple metal regulatory elements in mouse metallothionein-I promoter by assaying synthetic sequences. Nature (1985) 2.58
Transcriptional regulation of mouse liver metallothionein-I gene by glucocorticoids. Nature (1981) 2.58
Ethanol consumption and resistance are inversely related to neuropeptide Y levels. Nature (1998) 2.57
Elimination of zinc from synaptic vesicles in the intact mouse brain by disruption of the ZnT3 gene. Proc Natl Acad Sci U S A (1999) 2.50
Thermoregulatory and metabolic phenotypes of mice lacking noradrenaline and adrenaline. Nature (1997) 2.47
A transgenic mouse model of the chronic hepatitis B surface antigen carrier state. Science (1985) 2.47
Genetically haploid spermatids are phenotypically diploid. Nature (1989) 2.45
Prevention of NH2-terminal acetylation of proteins synthesized in cell-free systems. J Biol Chem (1977) 2.38
Targeted disruption of the tyrosine hydroxylase gene reveals that catecholamines are required for mouse fetal development. Nature (1995) 2.37
The dopamine beta-hydroxylase gene promoter directs expression of E. coli lacZ to sympathetic and other neurons in adult transgenic mice. Neuron (1991) 2.37
Spermatid-specific expression of protamine 1 in transgenic mice. Proc Natl Acad Sci U S A (1987) 2.36
Diabetes and tolerance in transgenic mice expressing class II MHC molecules in pancreatic beta cells. Cell (1988) 2.36
Pancreatic neoplasia induced by SV40 T-antigen expression in acinar cells of transgenic mice. Science (1987) 2.35
Targeted disruption of metallothionein I and II genes increases sensitivity to cadmium. Proc Natl Acad Sci U S A (1994) 2.34
Pancreatic neoplasia induced by ras expression in acinar cells of transgenic mice. Cell (1987) 2.32
Transgenic mice. Cell (1985) 2.30
Production of transgenic rabbits, sheep and pigs by microinjection. Nature (1985) 2.26
High-level erythroid expression of human alpha-globin genes in transgenic mice. Proc Natl Acad Sci U S A (1989) 2.26
Dopamine production in the caudate putamen restores feeding in dopamine-deficient mice. Neuron (2001) 2.24
Structural and pathological effects of synthesis of hepatitis B virus large envelope polypeptide in transgenic mice. Proc Natl Acad Sci U S A (1987) 2.24
Abnormal sexual development in transgenic mice chronically expressing müllerian inhibiting substance. Nature (1990) 2.20
Oncogene-induced liver neoplasia in transgenic mice. Oncogene (1989) 2.20
Organization of polysomes from pre-existing ribosomes in chick oviduct by a secondary administration of either estradiol or progesterone. J Biol Chem (1970) 2.12
The rat elastase I regulatory element is an enhancer that directs correct cell specificity and developmental onset of expression in transgenic mice. Mol Cell Biol (1987) 2.12
Glucocorticoid regulation of metallothionein-I mRNA synthesis in cultured mouse cells. J Biol Chem (1981) 2.12
SV40 enhancer and large-T antigen are instrumental in development of choroid plexus tumours in transgenic mice. Nature (1985) 2.10
Human beta-globin locus control region: analysis of the 5' DNase I hypersensitive site HS 2 in transgenic mice. Proc Natl Acad Sci U S A (1991) 2.06
Protamine 3'-untranslated sequences regulate temporal translational control and subcellular localization of growth hormone in spermatids of transgenic mice. Genes Dev (1989) 2.06
Restoration of norepinephrine and reversal of phenotypes in mice lacking dopamine beta-hydroxylase. J Neurochem (1998) 2.03
Induction of mouse metallothionein-I mRNA by bacterial endotoxin is independent of metals and glucocorticoid hormones. Proc Natl Acad Sci U S A (1984) 2.03
A metabolic defect promotes obesity in mice lacking melanocortin-4 receptors. Proc Natl Acad Sci U S A (2000) 2.02
The action of estrogen and progesterone on the expression of the transferrin gene. A comparison of the response in chick liver and oviduct. J Biol Chem (1978) 2.01
Altered behavior and long-term potentiation in type I adenylyl cyclase mutant mice. Proc Natl Acad Sci U S A (1995) 1.94
Precursor of egg white lysozyme. Amino acid sequence of an NH2-terminal extension. J Biol Chem (1977) 1.93
Induction of a new metallothionein isoform (MT-IV) occurs during differentiation of stratified squamous epithelia. Biochemistry (1994) 1.91
The NH2-terminal sequence of the avian oncovirus gag precursor polyprotein (Pr76gag). Virology (1978) 1.90
Ultrastructural localization of zinc transporter-3 (ZnT-3) to synaptic vesicle membranes within mossy fiber boutons in the hippocampus of mouse and monkey. Proc Natl Acad Sci U S A (1997) 1.89
A significant lag in the induction of ovalbumin messenger RNA by steroid hormones: a receptor translocation hypothesis. Cell (1976) 1.89
MT-III, a brain-specific member of the metallothionein gene family. Proc Natl Acad Sci U S A (1992) 1.84
Peripheral tolerance to an islet cell-specific hemagglutinin transgene affects both CD4+ and CD8+ T cells. Eur J Immunol (1992) 1.83
Neonatal bleeding in transgenic mice expressing urokinase-type plasminogen activator. Cell (1990) 1.83
Climate change and the integrity of science. Science (2010) 1.80
Islet amyloid formation associated with hyperglycemia in transgenic mice with pancreatic beta cell expression of human islet amyloid polypeptide. Proc Natl Acad Sci U S A (1996) 1.80
Targeted correction of a major histocompatibility class II E alpha gene by DNA microinjected into mouse eggs. Proc Natl Acad Sci U S A (1989) 1.77
Dwarf mice produced by genetic ablation of growth hormone-expressing cells. Genes Dev (1988) 1.74
Transgenic mice selectively lacking MHC class II (I-E) antigen expression on B cells: an in vivo approach to investigate Ia gene function. Cell (1987) 1.74
Growth enhancement of transgenic mice expressing human insulin-like growth factor I. Endocrinology (1988) 1.72
Pancreatic tumor pathogenesis reflects the causative genetic lesion. Proc Natl Acad Sci U S A (1991) 1.72