Published in Science on June 11, 1993
The nuts and bolts of AGC protein kinases. Nat Rev Mol Cell Biol (2010) 6.91
The S-R issue: its status in behavior analysis and in Donahoe and Palmer's learning and complex behavior. J Exp Anal Behav (1997) 3.63
Signaling networks: the origins of cellular multitasking. Cell (2000) 2.99
Toward a molecular definition of long-term memory storage. Proc Natl Acad Sci U S A (1996) 2.81
Different training procedures recruit either one or two critical periods for contextual memory consolidation, each of which requires protein synthesis and PKA. Learn Mem (1999) 2.72
Interactive cloning with the SH3 domain of N-src identifies a new brain specific ion channel protein, with homology to eag and cyclic nucleotide-gated channels. Proc Natl Acad Sci U S A (1997) 2.48
The molecular biology of memory: cAMP, PKA, CRE, CREB-1, CREB-2, and CPEB. Mol Brain (2012) 2.43
D1/D5 receptor agonists induce a protein synthesis-dependent late potentiation in the CA1 region of the hippocampus. Proc Natl Acad Sci U S A (1995) 2.42
Age-related defects in spatial memory are correlated with defects in the late phase of hippocampal long-term potentiation in vitro and are attenuated by drugs that enhance the cAMP signaling pathway. Proc Natl Acad Sci U S A (1999) 2.39
Epigenetic mechanisms in cognition. Neuron (2011) 2.31
Rolipram, a type IV-specific phosphodiesterase inhibitor, facilitates the establishment of long-lasting long-term potentiation and improves memory. Proc Natl Acad Sci U S A (1998) 2.31
Matrix metalloproteinase-9 is required for hippocampal late-phase long-term potentiation and memory. J Neurosci (2006) 2.23
Forward and reverse genetic approaches to behavior in the mouse. Science (1994) 2.20
Involvement of hippocampal cAMP/cAMP-dependent protein kinase signaling pathways in a late memory consolidation phase of aversively motivated learning in rats. Proc Natl Acad Sci U S A (1997) 2.20
Memory consolidation for contextual and auditory fear conditioning is dependent on protein synthesis, PKA, and MAP kinase. Learn Mem (1999) 2.06
A neoHebbian framework for episodic memory; role of dopamine-dependent late LTP. Trends Neurosci (2011) 2.04
Neuromodulation of thought: flexibilities and vulnerabilities in prefrontal cortical network synapses. Neuron (2012) 1.99
Activity-dependent regulation of synaptic clustering in a hippocampal culture system. Proc Natl Acad Sci U S A (1999) 1.97
Altered behavior and long-term potentiation in type I adenylyl cyclase mutant mice. Proc Natl Acad Sci U S A (1995) 1.94
Ubiquitination in postsynaptic function and plasticity. Annu Rev Cell Dev Biol (2010) 1.94
Spine expansion and stabilization associated with long-term potentiation. J Neurosci (2008) 1.91
Hippocampal synaptic plasticity: role in spatial learning or the automatic recording of attended experience? Philos Trans R Soc Lond B Biol Sci (1997) 1.91
Time-restricted role for dendritic activation of the mTOR-p70S6K pathway in the induction of late-phase long-term potentiation in the CA1. Proc Natl Acad Sci U S A (2003) 1.89
Age-dependent requirement of AKAP150-anchored PKA and GluR2-lacking AMPA receptors in LTP. EMBO J (2007) 1.88
Culturing pyramidal neurons from the early postnatal mouse hippocampus and cortex. Nat Protoc (2012) 1.79
The dendritic branch is the preferred integrative unit for protein synthesis-dependent LTP. Neuron (2011) 1.75
Interactions between membrane conductances underlying thalamocortical slow-wave oscillations. Physiol Rev (2003) 1.64
Epac2 induces synapse remodeling and depression and its disease-associated forms alter spines. Nat Neurosci (2009) 1.58
The function of activity-regulated genes in the nervous system. Physiol Rev (2009) 1.54
Mice lacking the gene encoding tissue-type plasminogen activator show a selective interference with late-phase long-term potentiation in both Schaffer collateral and mossy fiber pathways. Proc Natl Acad Sci U S A (1996) 1.54
"Silent" metaplasticity of the late phase of long-term potentiation requires protein phosphatases. Learn Mem (2002) 1.52
TORC1 is a calcium- and cAMP-sensitive coincidence detector involved in hippocampal long-term synaptic plasticity. Proc Natl Acad Sci U S A (2007) 1.52
Environmental enrichment modifies the PKA-dependence of hippocampal LTP and improves hippocampus-dependent memory. Learn Mem (2001) 1.50
Strain-dependent differences in LTP and hippocampus-dependent memory in inbred mice. Learn Mem (2000) 1.48
Prolonged wakefulness induces experience-dependent synaptic plasticity in mouse hypocretin/orexin neurons. J Clin Invest (2007) 1.45
Subcellular dynamics of type II PKA in neurons. Neuron (2009) 1.43
Synapses and memory storage. Cold Spring Harb Perspect Biol (2012) 1.39
Hippocampal long-term depression and depotentiation are defective in mice carrying a targeted disruption of the gene encoding the RI beta subunit of cAMP-dependent protein kinase. Proc Natl Acad Sci U S A (1995) 1.39
Repeated pulses of serotonin required for long-term facilitation activate mitogen-activated protein kinase in sensory neurons of Aplysia. Proc Natl Acad Sci U S A (1998) 1.37
Influence of actinomycin D, a RNA synthesis inhibitor, on long-term potentiation in rat hippocampal neurons in vivo and in vitro. J Physiol (1996) 1.34
Rheb interacts with Raf-1 kinase and may function to integrate growth factor- and protein kinase A-dependent signals. Mol Cell Biol (1997) 1.33
Mechanisms and function of dendritic exocytosis. Neuron (2011) 1.28
In search of general mechanisms for long-lasting plasticity: Aplysia and the hippocampus. Philos Trans R Soc Lond B Biol Sci (2003) 1.27
Expression of the circadian clock gene Period2 in the hippocampus: possible implications for synaptic plasticity and learned behaviour. ASN Neuro (2009) 1.26
Consolidation of memory for odor-reward association: beta-adrenergic receptor involvement in the late phase. Learn Mem (1999) 1.25
LRRK2 regulates synaptogenesis and dopamine receptor activation through modulation of PKA activity. Nat Neurosci (2014) 1.24
Disrupted sleep without sleep curtailment induces sleepiness and cognitive dysfunction via the tumor necrosis factor-α pathway. J Neuroinflammation (2012) 1.23
Presynaptic mechanisms underlying cannabinoid inhibition of excitatory synaptic transmission in rat striatal neurons. J Physiol (2001) 1.22
Persistence of coordinated long-term potentiation and dendritic spine enlargement at mature hippocampal CA1 synapses requires N-cadherin. J Neurosci (2010) 1.22
Impaired hippocampal plasticity in mice lacking the Cbeta1 catalytic subunit of cAMP-dependent protein kinase. Proc Natl Acad Sci U S A (1996) 1.21
Proteasome inhibition enhances the induction and impairs the maintenance of late-phase long-term potentiation. Learn Mem (2008) 1.20
Requirement of beta-adrenergic receptor activation and protein synthesis for LTP-reinforcement by novelty in rat dentate gyrus. J Physiol (2003) 1.20
5-Hydroxytryptamine (5-HT)4 receptors in post mortem human brain tissue: distribution, pharmacology and effects of neurodegenerative diseases. Br J Pharmacol (1995) 1.18
Phosphorylation of presynaptic and postsynaptic calcium channels by cAMP-dependent protein kinase in hippocampal neurons. EMBO J (1995) 1.18
Epac mediates PACAP-dependent long-term depression in the hippocampus. J Physiol (2008) 1.17
Alpha2A-adrenoceptor stimulation improves prefrontal cortical regulation of behavior through inhibition of cAMP signaling in aging animals. Learn Mem (2006) 1.14
Spike timing dependent plasticity: a consequence of more fundamental learning rules. Front Comput Neurosci (2010) 1.13
Activity-regulated genes as mediators of neural circuit plasticity. Prog Neurobiol (2011) 1.13
Melatonin inhibits hippocampal long-term potentiation. Eur J Neurosci (2005) 1.12
Considerations for the use of SH-SY5Y neuroblastoma cells in neurobiology. Methods Mol Biol (2013) 1.12
AMPA receptor regulation during synaptic plasticity in hippocampus and neocortex. Semin Cell Dev Biol (2011) 1.11
Activation of exchange protein activated by cyclic-AMP enhances long-lasting synaptic potentiation in the hippocampus. Learn Mem (2008) 1.11
PKA has a critical role in synaptic delivery of GluR1- and GluR4-containing AMPARs during initial stages of acquisition of in vitro classical conditioning. J Neurophysiol (2009) 1.10
Cyclic AMP-dependent protein kinase phosphorylates group III metabotropic glutamate receptors and inhibits their function as presynaptic receptors. J Neurochem (2001) 1.09
Identification of transmitter systems and learning tag molecules involved in behavioral tagging during memory formation. Proc Natl Acad Sci U S A (2011) 1.09
Steel mutant mice are deficient in hippocampal learning but not long-term potentiation. Proc Natl Acad Sci U S A (1996) 1.07
Forskolin induction of late-LTP and up-regulation of 5' TOP mRNAs translation via mTOR, ERK, and PI3K in hippocampal pyramidal cells. J Neurochem (2008) 1.07
The long-term stability of new hippocampal place fields requires new protein synthesis. Proc Natl Acad Sci U S A (2004) 1.06
Dopaminergic modulation of the hippocampal neuropil proteome identified by bioorthogonal noncanonical amino acid tagging (BONCAT). Proteomics (2012) 1.05
NMDA receptor-dependent long-term potentiation comprises a family of temporally overlapping forms of synaptic plasticity that are induced by different patterns of stimulation. Philos Trans R Soc Lond B Biol Sci (2013) 1.05
Dopaminergic modulation of auditory cortex-dependent memory consolidation through mTOR. Cereb Cortex (2008) 1.05
Genetic disruption of protein kinase A anchoring reveals a role for compartmentalized kinase signaling in theta-burst long-term potentiation and spatial memory. J Neurosci (2007) 1.04
Cdk5 is required for memory function and hippocampal plasticity via the cAMP signaling pathway. PLoS One (2011) 1.04
Parallel somatic and synaptic processing in the induction of intermediate-term and long-term synaptic facilitation in Aplysia. Proc Natl Acad Sci U S A (2004) 1.04
AKAP79/150 interacts with AC8 and regulates Ca2+-dependent cAMP synthesis in pancreatic and neuronal systems. J Biol Chem (2010) 1.03
Regulation of AMPA receptor trafficking in the nucleus accumbens by dopamine and cocaine. Neurotox Res (2010) 1.01
GEBR-7b, a novel PDE4D selective inhibitor that improves memory in rodents at non-emetic doses. Br J Pharmacol (2011) 1.00
Bidirectional synaptic plasticity and spatial memory flexibility require Ca2+-stimulated adenylyl cyclases. J Neurosci (2011) 1.00
Selective PDE inhibitors rolipram and sildenafil improve object retrieval performance in adult cynomolgus macaques. Psychopharmacology (Berl) (2007) 1.00
A model of the roles of essential kinases in the induction and expression of late long-term potentiation. Biophys J (2006) 1.00
Inhibition of phosphodiesterase-4 reverses memory deficits produced by Aβ25-35 or Aβ1-40 peptide in rats. Psychopharmacology (Berl) (2010) 0.99
Temporal sensitivity of protein kinase a activation in late-phase long term potentiation. PLoS Comput Biol (2010) 0.99
Compartmentalized PKA signaling events are required for synaptic tagging and capture during hippocampal late-phase long-term potentiation. Eur J Cell Biol (2006) 0.99
Guanfacine for the treatment of cognitive disorders: a century of discoveries at Yale. Yale J Biol Med (2012) 0.99
Cytokine responses to LTP induction in the rat hippocampus: a comparison of in vitro and in vivo techniques. Learn Mem (2001) 0.99
Metaplasticity of the late-phase of long-term potentiation: a critical role for protein kinase A in synaptic tagging. Eur J Neurosci (2006) 0.98
Cognitive and emotional information processing: protein synthesis and gene expression. J Physiol (2007) 0.97
D1/5 receptor-mediated enhancement of LTP requires PKA, Src family kinases, and NR2B-containing NMDARs. Neuropharmacology (2008) 0.97
Sildenafil restores cognitive function without affecting β-amyloid burden in a mouse model of Alzheimer's disease. Br J Pharmacol (2011) 0.96
Long-term potentiation decay and memory loss are mediated by AMPAR endocytosis. J Clin Invest (2014) 0.96
Long-term potentiation and long-term depression: a clinical perspective. Clinics (Sao Paulo) (2011) 0.95
Platelet-derived growth factor-mediated induction of the synaptic plasticity gene Arc/Arg3.1. J Biol Chem (2010) 0.94
Dual acylation of PDE2A splice variant 3: targeting to synaptic membranes. J Biol Chem (2009) 0.94
Mechanisms of induction and maintenance of spike-timing dependent plasticity in biophysical synapse models. Front Comput Neurosci (2010) 0.94
Distinct prefrontal molecular mechanisms for information storage lasting seconds versus minutes. Learn Mem (2005) 0.94
Long-Term Potentiation at CA3-CA1 Hippocampal Synapses with Special Emphasis on Aging, Disease, and Stress. Front Aging Neurosci (2011) 0.94
The role of the direct perforant path input to the CA1 subregion of the dorsal hippocampus in memory retention and retrieval. Hippocampus (2007) 0.94
Histaminergic mechanisms for modulation of memory systems. Neural Plast (2011) 0.94
Gravin orchestrates protein kinase A and β2-adrenergic receptor signaling critical for synaptic plasticity and memory. J Neurosci (2012) 0.94
Acute stress causes rapid synaptic insertion of Ca2+ -permeable AMPA receptors to facilitate long-term potentiation in the hippocampus. Brain (2013) 0.93
Subregion- and cell type-restricted gene knockout in mouse brain. Cell (1996) 8.02
Control of memory formation through regulated expression of a CaMKII transgene. Science (1996) 7.56
Cognitive neuroscience and the study of memory. Neuron (1998) 6.22
Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice. Neuron (1996) 5.19
Genetic demonstration of a role for PKA in the late phase of LTP and in hippocampus-based long-term memory. Cell (1997) 4.83
Impaired long-term potentiation, spatial learning, and hippocampal development in fyn mutant mice. Science (1992) 4.58
Molecular biology of learning: modulation of transmitter release. Science (1982) 4.44
Synapse-specific, long-term facilitation of aplysia sensory to motor synapses: a function for local protein synthesis in memory storage. Cell (1997) 3.93
Identification of a gene encoding a hyperpolarization-activated pacemaker channel of brain. Cell (1998) 3.90
Requirement of a critical period of transcription for induction of a late phase of LTP. Science (1994) 3.85
The long and the short of long-term memory--a molecular framework. Nature (1986) 3.68
Serotonin and cyclic AMP close single K+ channels in Aplysia sensory neurones. Nature (1982) 3.61
p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage. Nature (1999) 3.55
A critical period for macromolecular synthesis in long-term heterosynaptic facilitation in Aplysia. Science (1986) 3.30
Tissue-plasminogen activator is induced as an immediate-early gene during seizure, kindling and long-term potentiation. Nature (1993) 3.23
Anomalous rectification in the metacerebral giant cells and its consequences for synaptic transmission. J Physiol (1966) 3.18
Structural changes accompanying memory storage. Annu Rev Physiol (1993) 3.11
Injection of the cAMP-responsive element into the nucleus of Aplysia sensory neurons blocks long-term facilitation. Nature (1990) 2.85
Toward a molecular definition of long-term memory storage. Proc Natl Acad Sci U S A (1996) 2.81
A transient, neuron-wide form of CREB-mediated long-term facilitation can be stabilized at specific synapses by local protein synthesis. Cell (1999) 2.77
Aplysia CREB2 represses long-term facilitation: relief of repression converts transient facilitation into long-term functional and structural change. Cell (1995) 2.75
Different training procedures recruit either one or two critical periods for contextual memory consolidation, each of which requires protein synthesis and PKA. Learn Mem (1999) 2.72
Synaptic facilitation and behavioral sensitization in Aplysia: possible role of serotonin and cyclic AMP. Science (1976) 2.72
The 3'-untranslated region of CaMKII alpha is a cis-acting signal for the localization and translation of mRNA in dendrites. Proc Natl Acad Sci U S A (1996) 2.70
Presynaptic modulation of voltage-dependent Ca2+ current: mechanism for behavioral sensitization in Aplysia californica. Proc Natl Acad Sci U S A (1978) 2.68
Tests of the roles of two diffusible substances in long-term potentiation: evidence for nitric oxide as a possible early retrograde messenger. Proc Natl Acad Sci U S A (1991) 2.64
Inducible and reversible enhancement of learning, memory, and long-term potentiation by genetic inhibition of calcineurin. Cell (2001) 2.62
cAMP contributes to mossy fiber LTP by initiating both a covalently mediated early phase and macromolecular synthesis-dependent late phase. Cell (1994) 2.59
Some forms of cAMP-mediated long-lasting potentiation are associated with release of BDNF and nuclear translocation of phospho-MAP kinase. Neuron (2001) 2.59
Spatially resolved dynamics of cAMP and protein kinase A subunits in Aplysia sensory neurons. Science (1993) 2.51
MAP kinase translocates into the nucleus of the presynaptic cell and is required for long-term facilitation in Aplysia. Neuron (1997) 2.50
A serotonin transporter gene promoter polymorphism (5-HTTLPR) and prefrontal cortical binding in major depression and suicide. Arch Gen Psychiatry (2000) 2.50
Ubiquitin C-terminal hydrolase is an immediate-early gene essential for long-term facilitation in Aplysia. Cell (1997) 2.50
Interactive cloning with the SH3 domain of N-src identifies a new brain specific ion channel protein, with homology to eag and cyclic nucleotide-gated channels. Proc Natl Acad Sci U S A (1997) 2.48
Neuronal mechanisms of habituation and dishabituation of the gill-withdrawal reflex in Aplysia. Science (1970) 2.43
C/EBP is an immediate-early gene required for the consolidation of long-term facilitation in Aplysia. Cell (1994) 2.42
D1/D5 receptor agonists induce a protein synthesis-dependent late potentiation in the CA1 region of the hippocampus. Proc Natl Acad Sci U S A (1995) 2.42
Recruitment of long-lasting and protein kinase A-dependent long-term potentiation in the CA1 region of hippocampus requires repeated tetanization. Learn Mem (1999) 2.41
Age-related defects in spatial memory are correlated with defects in the late phase of hippocampal long-term potentiation in vitro and are attenuated by drugs that enhance the cAMP signaling pathway. Proc Natl Acad Sci U S A (1999) 2.39
Lipoxygenase metabolites of arachidonic acid as second messengers for presynaptic inhibition of Aplysia sensory cells. Nature (1987) 2.32
APP processing and synaptic plasticity in presenilin-1 conditional knockout mice. Neuron (2001) 2.31
Long-term potentiation in the hippocampus using depolarizing current pulses as the conditioning stimulus to single volley synaptic potentials. J Neurosci (1987) 2.30
CREB1 encodes a nuclear activator, a repressor, and a cytoplasmic modulator that form a regulatory unit critical for long-term facilitation. Cell (1998) 2.27
Presynaptic facilitation as a mechanism for behavioral sensitization in Aplysia. Science (1976) 2.27
Mechanism of calcium current modulation underlying presynaptic facilitation and behavioral sensitization in Aplysia. Proc Natl Acad Sci U S A (1980) 2.26
Abolition of long-term stability of new hippocampal place cell maps by NMDA receptor blockade. Science (1998) 2.25
A cellular mechanism of classical conditioning in Aplysia: activity-dependent amplification of presynaptic facilitation. Science (1983) 2.25
Intracellular injection of t he catalytic subunit of cyclic AMP-dependent protein kinase simulates facilitation of transmitter release underlying behavioral sensitization in Aplysia. Proc Natl Acad Sci U S A (1980) 2.24
Selective elimination of mRNAs in vivo: complementary oligodeoxynucleotides promote RNA degradation by an RNase H-like activity. Proc Natl Acad Sci U S A (1987) 2.23
Serotonin modulates a specific potassium current in the sensory neurons that show presynaptic facilitation in Aplysia. Proc Natl Acad Sci U S A (1982) 2.19
Impairment of spatial but not contextual memory in CaMKII mutant mice with a selective loss of hippocampal LTP in the range of the theta frequency. Cell (1995) 2.19
CaMKII regulates the frequency-response function of hippocampal synapses for the production of both LTD and LTP. Cell (1995) 2.16
Tissue plasminogen activator contributes to the late phase of LTP and to synaptic growth in the hippocampal mossy fiber pathway. Neuron (1998) 2.13
Cyclic AMP induces functional presynaptic boutons in hippocampal CA3-CA1 neuronal cultures. Nat Neurosci (1999) 2.08
Activation of cAMP-responsive genes by stimuli that produce long-term facilitation in Aplysia sensory neurons. Neuron (1993) 2.05
Presynaptic facilitation revisited: state and time dependence. J Neurosci (1996) 2.04
Genetic and pharmacological evidence for a novel, intermediate phase of long-term potentiation suppressed by calcineurin. Cell (1998) 2.04
cAMP response element-binding protein is activated by Ca2+/calmodulin- as well as cAMP-dependent protein kinase. Proc Natl Acad Sci U S A (1991) 2.04
A quantal analysis of the synaptic depression underlying habituation of the gill-withdrawal reflex in Aplysia. Proc Natl Acad Sci U S A (1974) 2.04
Study of Dengue virus infection in SCID mice engrafted with human K562 cells. J Virol (1998) 2.03
Long-term potentiation in the hippocampus is blocked by tyrosine kinase inhibitors. Nature (1991) 2.02
Aggressivity, suicide attempts, and depression: relationship to cerebrospinal fluid monoamine metabolite levels. Biol Psychiatry (2001) 2.00
Mutation in the phosphorylation sites of MAP kinase blocks learning-related internalization of apCAM in Aplysia sensory neurons. Neuron (1997) 1.98
ERK plays a regulatory role in induction of LTP by theta frequency stimulation and its modulation by beta-adrenergic receptors. Neuron (1999) 1.97
Long-term sensitization of a defensive withdrawal reflex in Aplysia. Science (1973) 1.90
Long-term habituation of a defensive withdrawal reflex in aplysia. Science (1972) 1.89
Nitric oxide and carbon monoxide produce activity-dependent long-term synaptic enhancement in hippocampus. Science (1993) 1.89
Postsynaptic induction and PKA-dependent expression of LTP in the lateral amygdala. Neuron (1998) 1.87
Restricted and regulated overexpression reveals calcineurin as a key component in the transition from short-term to long-term memory. Cell (1998) 1.85
Inducible and reversible gene expression with the rtTA system for the study of memory. Neuron (1998) 1.81
Nitric oxide signaling contributes to late-phase LTP and CREB phosphorylation in the hippocampus. J Neurosci (1999) 1.79
Modulation of an NCAM-related adhesion molecule with long-term synaptic plasticity in Aplysia. Science (1992) 1.78
Functioning of identified neurons and synapses in abdominal ganglion of Aplysia in absence of protein synthesis. J Neurophysiol (1971) 1.77
Both protein kinase A and mitogen-activated protein kinase are required in the amygdala for the macromolecular synthesis-dependent late phase of long-term potentiation. J Neurosci (2000) 1.77
Memory suppressor genes: inhibitory constraints on the storage of long-term memory. Science (1998) 1.76
Rescuing impairment of long-term potentiation in fyn-deficient mice by introducing Fyn transgene. Proc Natl Acad Sci U S A (1997) 1.75
A macromolecular synthesis-dependent late phase of long-term potentiation requiring cAMP in the medial perforant pathway of rat hippocampal slices. J Neurosci (1996) 1.74
Cyclic AMP-dependent protein kinase closes the serotonin-sensitive K+ channels of Aplysia sensory neurones in cell-free membrane patches. Nature (1985) 1.73
Electrophysiological properties and functional interconnections of two symmetrical neurosecretory clusters (bag cells) in abdominal ganglion of Aplysia. J Neurophysiol (1970) 1.71
Persistence of Japanese encephalitis virus is associated with abnormal expression of the nonstructural protein NS1 in host cells. Virology (1996) 1.69
Depletion of serotonin in the nervous system of Aplysia reduces the behavioral enhancement of gill withdrawal as well as the heterosynaptic facilitation produced by tail shock. J Neurosci (1989) 1.69
Role of guanylyl cyclase and cGMP-dependent protein kinase in long-term potentiation. Nature (1994) 1.68
Mice expressing activated CaMKII lack low frequency LTP and do not form stable place cells in the CA1 region of the hippocampus. Cell (1996) 1.67
Calcineurin-mediated LTD of GABAergic inhibition underlies the increased excitability of CA1 neurons associated with LTP. Neuron (2000) 1.67
Intrasomatic injection of radioactive precursors for studying transmitter synthesis in identified neurons of Aplysia californica. Proc Natl Acad Sci U S A (1973) 1.66
Direct and common connections among identified neurons in Aplysia. J Neurophysiol (1967) 1.65
Nitric oxide acts directly in the presynaptic neuron to produce long-term potentiation in cultured hippocampal neurons. Cell (1996) 1.63
Genetic approaches to memory storage. Trends Genet (1999) 1.63
Activity-dependent long-term enhancement of transmitter release by presynaptic 3',5'-cyclic GMP in cultured hippocampal neurons. Nature (1995) 1.63
Heterosynaptic facilitation in neurones of the abdominal ganglion of Aplysia depilans. J Physiol (1965) 1.62
Serotonin-mediated endocytosis of apCAM: an early step of learning-related synaptic growth in Aplysia. Science (1992) 1.62
Long-term potentiation is reduced in mice that are doubly mutant in endothelial and neuronal nitric oxide synthase. Cell (1996) 1.61
Is heterosynaptic modulation essential for stabilizing Hebbian plasticity and memory? Nat Rev Neurosci (2000) 1.60
Drought-induced increases in abscisic Acid levels in the root apex of sunflower. Plant Physiol (1985) 1.59
A VAMP-binding protein from Aplysia required for neurotransmitter release. Science (1995) 1.57
Endothelial NOS and the blockade of LTP by NOS inhibitors in mice lacking neuronal NOS. Science (1994) 1.56
Mice lacking the gene encoding tissue-type plasminogen activator show a selective interference with late-phase long-term potentiation in both Schaffer collateral and mossy fiber pathways. Proc Natl Acad Sci U S A (1996) 1.54