Published in J Cell Biol on December 01, 1996
The dynamin-related GTPase, Dnm1p, controls mitochondrial morphology in yeast. J Cell Biol (1998) 4.72
AP-2/Eps15 interaction is required for receptor-mediated endocytosis. J Cell Biol (1998) 3.30
Binding specificity and in vivo targets of the EH domain, a novel protein-protein interaction module. Genes Dev (1997) 3.01
Vacuole biogenesis in Saccharomyces cerevisiae: protein transport pathways to the yeast vacuole. Microbiol Mol Biol Rev (1998) 2.59
Monoubiquitin carries a novel internalization signal that is appended to activated receptors. EMBO J (2000) 2.54
Pan1p, yeast eps15, functions as a multivalent adaptor that coordinates protein-protein interactions essential for endocytosis. J Cell Biol (1998) 2.43
Genetic analysis of endocytosis in Caenorhabditis elegans: coelomocyte uptake defective mutants. Genetics (2001) 2.35
She2p is a novel RNA-binding protein that recruits the Myo4p-She3p complex to ASH1 mRNA. EMBO J (2000) 2.17
The myosin motor, Myo4p, binds Ash1 mRNA via the adapter protein, She3p. Proc Natl Acad Sci U S A (2000) 2.09
Signalling to actin assembly via the WASP (Wiskott-Aldrich syndrome protein)-family proteins and the Arp2/3 complex. Biochem J (2004) 2.08
Synthesis and function of membrane phosphoinositides in budding yeast, Saccharomyces cerevisiae. Biochim Biophys Acta (2007) 2.08
Role for Drs2p, a P-type ATPase and potential aminophospholipid translocase, in yeast late Golgi function. J Cell Biol (1999) 2.07
She2p, a novel RNA-binding protein tethers ASH1 mRNA to the Myo4p myosin motor via She3p. EMBO J (2000) 2.06
Sphingoid base synthesis requirement for endocytosis in Saccharomyces cerevisiae. EMBO J (2000) 2.06
Live cell imaging of the assembly, disassembly, and actin cable-dependent movement of endosomes and actin patches in the budding yeast, Saccharomyces cerevisiae. J Cell Biol (2004) 1.87
Identification of a novel domain shared by putative components of the endocytic and cytoskeletal machinery. Protein Sci (1999) 1.84
Regulation of Fab1 phosphatidylinositol 3-phosphate 5-kinase pathway by Vac7 protein and Fig4, a polyphosphoinositide phosphatase family member. Mol Biol Cell (2002) 1.84
The yeast actin-related protein Arp2p is required for the internalization step of endocytosis. Mol Biol Cell (1997) 1.83
The EH and SH3 domain Ese proteins regulate endocytosis by linking to dynamin and Eps15. EMBO J (1999) 1.82
Arp2 links autophagic machinery with the actin cytoskeleton. Mol Biol Cell (2008) 1.80
EH domain proteins Pan1p and End3p are components of a complex that plays a dual role in organization of the cortical actin cytoskeleton and endocytosis in Saccharomyces cerevisiae. Mol Cell Biol (1997) 1.78
Unc-45 mutations in Caenorhabditis elegans implicate a CRO1/She4p-like domain in myosin assembly. J Cell Biol (1998) 1.78
Pan1p, End3p, and S1a1p, three yeast proteins required for normal cortical actin cytoskeleton organization, associate with each other and play essential roles in cell wall morphogenesis. Mol Cell Biol (2000) 1.76
The F-box protein Rcy1p is involved in endocytic membrane traffic and recycling out of an early endosome in Saccharomyces cerevisiae. J Cell Biol (2000) 1.70
Eps15 and Dap160 control synaptic vesicle membrane retrieval and synapse development. J Cell Biol (2007) 1.64
The Khd1 protein, which has three KH RNA-binding motifs, is required for proper localization of ASH1 mRNA in yeast. EMBO J (2002) 1.62
An exclusively nuclear RNA-binding protein affects asymmetric localization of ASH1 mRNA and Ash1p in yeast. J Cell Biol (2001) 1.58
Sla1p serves as the targeting signal recognition factor for NPFX(1,2)D-mediated endocytosis. J Cell Biol (2002) 1.56
mRNAs encoding polarity and exocytosis factors are cotransported with the cortical endoplasmic reticulum to the incipient bud in Saccharomyces cerevisiae. Mol Cell Biol (2007) 1.51
Morphology of the yeast endocytic pathway. Mol Biol Cell (1998) 1.43
Regulation of the actin cytoskeleton organization in yeast by a novel serine/threonine kinase Prk1p. J Cell Biol (1999) 1.42
Probing the membrane environment of the TOR kinases reveals functional interactions between TORC1, actin, and membrane trafficking in Saccharomyces cerevisiae. Mol Biol Cell (2007) 1.41
Visualization of receptor-mediated endocytosis in yeast. Mol Biol Cell (1999) 1.39
Eps15 is recruited to the plasma membrane upon epidermal growth factor receptor activation and localizes to components of the endocytic pathway during receptor internalization. Mol Biol Cell (1999) 1.36
Actin-binding verprolin is a polarity development protein required for the morphogenesis and function of the yeast actin cytoskeleton. J Cell Biol (1997) 1.33
Mot3 is a transcriptional repressor of ergosterol biosynthetic genes and is required for normal vacuolar function in Saccharomyces cerevisiae. EMBO J (2002) 1.29
She4p/Dim1p interacts with the motor domain of unconventional myosins in the budding yeast, Saccharomyces cerevisiae. Mol Biol Cell (2003) 1.29
Caenorhabditis elegans UNC-45 is a component of muscle thick filaments and colocalizes with myosin heavy chain B, but not myosin heavy chain A. J Cell Biol (2000) 1.28
Lessons from yeast for clathrin-mediated endocytosis. Nat Cell Biol (2011) 1.28
Daughter-specific repression of Saccharomyces cerevisiae HO: Ash1 is the commander. EMBO Rep (2004) 1.23
The yeast GRD20 gene is required for protein sorting in the trans-Golgi network/endosomal system and for polarization of the actin cytoskeleton. Mol Biol Cell (1999) 1.23
Receptor internalization in yeast requires the Tor2-Rho1 signaling pathway. Mol Biol Cell (2003) 1.23
Aggregation of expanded polyglutamine domain in yeast leads to defects in endocytosis. Mol Cell Biol (2003) 1.21
Distinct functions of calmodulin are required for the uptake step of receptor-mediated endocytosis in yeast: the type I myosin Myo5p is one of the calmodulin targets. EMBO J (1998) 1.19
In vivo role for actin-regulating kinases in endocytosis and yeast epsin phosphorylation. Mol Biol Cell (2001) 1.17
Distinct roles for Khd1p in the localization and expression of bud-localized mRNAs in yeast. RNA (2008) 1.16
Scd5p and clathrin function are important for cortical actin organization, endocytosis, and localization of sla2p in yeast. Mol Biol Cell (2002) 1.16
A novel fluorescence-based genetic strategy identifies mutants of Saccharomyces cerevisiae defective for nuclear pore complex assembly. Mol Biol Cell (1998) 1.12
Morphology and dynamics of the endocytic pathway in Dictyostelium discoideum. Mol Biol Cell (2002) 1.12
A homologue of the yeast SHE4 gene is essential for the transition between the syncytial and cellular stages during sexual reproduction of the fungus Podospora anserina. EMBO J (1998) 1.08
Generation of an isogenic collection of yeast actin mutants and identification of three interrelated phenotypes. Genetics (2001) 1.03
Negative regulation of yeast Eps15-like Arp2/3 complex activator, Pan1p, by the Hip1R-related protein, Sla2p, during endocytosis. Mol Biol Cell (2006) 1.03
ASH1 mRNA localization in three acts. Mol Biol Cell (2001) 1.01
Functional interactions between the p35 subunit of the Arp2/3 complex and calmodulin in yeast. Mol Biol Cell (2000) 1.01
Actin and endocytosis in budding yeast. Genetics (2015) 0.99
Identification of novel recognition motifs and regulatory targets for the yeast actin-regulating kinase Prk1p. Mol Biol Cell (2003) 0.98
RNA asymmetric distribution and daughter/mother differentiation in yeast. Curr Opin Microbiol (2003) 0.97
Yeast Vps55p, a functional homolog of human obesity receptor gene-related protein, is involved in late endosome to vacuole trafficking. Mol Biol Cell (2002) 0.96
Isolation of yeast mutants defective for localization of vacuolar vital dyes. Proc Natl Acad Sci U S A (1998) 0.95
Interaction of the endocytic scaffold protein Pan1 with the type I myosins contributes to the late stages of endocytosis. Mol Biol Cell (2007) 0.93
mRNA trafficking in fungi. Mol Genet Genomics (2007) 0.93
Coupling actin dynamics to the endocytic process in Saccharomyces cerevisiae. Protoplasma (2005) 0.90
X-ray crystal structure of the UCS domain-containing UNC-45 myosin chaperone from Drosophila melanogaster. Structure (2011) 0.89
Myosin chaperones. Curr Opin Struct Biol (2013) 0.87
A quantitative imaging-based screen reveals the exocyst as a network hub connecting endocytosis and exocytosis. Mol Biol Cell (2015) 0.86
Genome-scale analyses of butanol tolerance in Saccharomyces cerevisiae reveal an essential role of protein degradation. Biotechnol Biofuels (2013) 0.86
Regulation of clathrin-mediated endocytosis by dynamic ubiquitination and deubiquitination. Curr Biol (2014) 0.84
Regulation of clathrin coat assembly by Eps15 homology domain-mediated interactions during endocytosis. Mol Biol Cell (2011) 0.82
Regulation of Alr1 Mg transporter activity by intracellular magnesium. PLoS One (2011) 0.82
Axl2 integrates polarity establishment, maintenance, and environmental stress response in the filamentous fungus Ashbya gossypii. Eukaryot Cell (2011) 0.80
A novel function of Arp2p in mediating Prk1p-specific regulation of actin and endocytosis in yeast. Mol Biol Cell (2007) 0.80
Intracellular glycosylphosphatidylinositols accumulate on endosomes: toxicity of alpha-toxin to Leishmania major. Eukaryot Cell (2005) 0.80
The proteolytic landscape of the yeast vacuole. Cell Logist (2014) 0.80
Dynamin- and Rab5-dependent endocytosis is required to prevent Drosophila photoreceptor degeneration. J Cell Sci (2011) 0.80
Pan1 regulates transitions between stages of clathrin-mediated endocytosis. Mol Biol Cell (2015) 0.79
A Pan1/End3/Sla1 complex links Arp2/3-mediated actin assembly to sites of clathrin-mediated endocytosis. Mol Biol Cell (2015) 0.78
Classifying transcription factor targets and discovering relevant biological features. Biol Direct (2008) 0.78
Mutation of the Ser18 phosphorylation site on the sole Saccharomyces cerevisiae UCS protein, She4, can compromise high-temperature survival. Cell Stress Chaperones (2016) 0.75
Beyond Agar: Gel Substrates with Improved Optical Clarity and Drug Efficiency and Reduced Autofluorescence for Microbial Growth Experiments. Appl Environ Microbiol (2015) 0.75
Selection and stabilization of endocytic sites by Ede1, a yeast functional homolog of the human Eps15. Mol Biol Cell (2017) 0.75
Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors. Gene (1985) 213.67
A Saccharomyces cerevisiae genomic plasmid bank based on a centromere-containing shuttle vector. Gene (1987) 19.68
Structural rearrangements of tubulin and actin during the cell cycle of the yeast Saccharomyces. J Cell Biol (1984) 14.58
Relationship of actin and tubulin distribution to bud growth in wild-type and morphogenetic-mutant Saccharomyces cerevisiae. J Cell Biol (1984) 13.62
Protein sorting in Saccharomyces cerevisiae: isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolases. Mol Cell Biol (1988) 13.27
Caveolin, a protein component of caveolae membrane coats. Cell (1992) 12.50
A new vital stain for visualizing vacuolar membrane dynamics and endocytosis in yeast. J Cell Biol (1995) 12.18
Early stages in the yeast secretory pathway are required for transport of carboxypeptidase Y to the vacuole. Cell (1982) 10.55
Phenotypic analysis of temperature-sensitive yeast actin mutants. Cell (1985) 8.53
Identification of a ten-amino acid proline-rich SH3 binding site. Science (1993) 8.05
Role of the coated endocytic vesicle in the uptake of receptor-bound low density lipoprotein in human fibroblasts. Cell (1977) 7.74
Structural basis for the binding of proline-rich peptides to SH3 domains. Cell (1994) 6.34
Regulated internalization of caveolae. J Cell Biol (1994) 5.77
The Saccharomyces cerevisiae MYO2 gene encodes an essential myosin for vectorial transport of vesicles. J Cell Biol (1991) 5.73
Characterization of VPS34, a gene required for vacuolar protein sorting and vacuole segregation in Saccharomyces cerevisiae. Mol Cell Biol (1990) 5.25
end3 and end4: two mutants defective in receptor-mediated and fluid-phase endocytosis in Saccharomyces cerevisiae. J Cell Biol (1993) 5.22
Ultrastructure of the yeast actin cytoskeleton and its association with the plasma membrane. J Cell Biol (1994) 5.14
Receptor-mediated endocytosis of transferrin in developmentally totipotent mouse teratocarcinoma stem cells. J Biol Chem (1981) 4.86
Multilamellar endosome-like compartment accumulates in the yeast vps28 vacuolar protein sorting mutant. Mol Biol Cell (1996) 4.71
Actin and fimbrin are required for the internalization step of endocytosis in yeast. EMBO J (1993) 4.39
The role of Myo2, a yeast class V myosin, in vesicular transport. J Cell Biol (1995) 4.11
Synthetic-lethal interactions identify two novel genes, SLA1 and SLA2, that control membrane cytoskeleton assembly in Saccharomyces cerevisiae. J Cell Biol (1993) 4.03
Actin microfilaments play a critical role in endocytosis at the apical but not the basolateral surface of polarized epithelial cells. J Cell Biol (1993) 4.00
The glycophospholipid-linked folate receptor internalizes folate without entering the clathrin-coated pit endocytic pathway. J Cell Biol (1990) 3.96
Clathrin-independent pinocytosis is induced in cells overexpressing a temperature-sensitive mutant of dynamin. J Cell Biol (1995) 3.92
Homology of a yeast actin-binding protein to signal transduction proteins and myosin-I. Nature (1990) 3.90
Distinct endocytotic pathways in epidermal growth factor-stimulated human carcinoma A431 cells. J Cell Biol (1989) 3.58
Mother cell-specific HO expression in budding yeast depends on the unconventional myosin myo4p and other cytoplasmic proteins. Cell (1996) 3.51
Construction and genetic characterization of temperature-sensitive mutant alleles of the yeast actin gene. Proc Natl Acad Sci U S A (1984) 3.47
The END3 gene encodes a protein that is required for the internalization step of endocytosis and for actin cytoskeleton organization in yeast. Mol Biol Cell (1994) 3.43
Comparative study of the properties of the purified internal and external invertases from yeast. J Biol Chem (1968) 3.42
Endocytosis is required for the growth of vacuolar H(+)-ATPase-defective yeast: identification of six new END genes. J Cell Biol (1994) 3.27
Patterns of bud-site selection in the yeast Saccharomyces cerevisiae. J Cell Biol (1995) 3.25
Yeast endocytosis assays. Methods Enzymol (1991) 3.24
Translation initiation requires the PAB-dependent poly(A) ribonuclease in yeast. Cell (1992) 3.20
The coated pit and macropinocytic pathways serve distinct endosome populations. J Cell Biol (1994) 3.09
end5, end6, and end7: mutations that cause actin delocalization and block the internalization step of endocytosis in Saccharomyces cerevisiae. Mol Biol Cell (1995) 3.08
Detection of an intermediate compartment involved in transport of alpha-factor from the plasma membrane to the vacuole in yeast. J Cell Biol (1990) 3.06
eps15, a novel tyrosine kinase substrate, exhibits transforming activity. Mol Cell Biol (1993) 3.03
Modulation of membrane dynamics and cell motility by membrane tension. Trends Cell Biol (1996) 2.94
Protein transport to the vacuole and receptor-mediated endocytosis by clathrin heavy chain-deficient yeast. J Cell Biol (1988) 2.86
Characterization of TPM1 disrupted yeast cells indicates an involvement of tropomyosin in directed vesicular transport. J Cell Biol (1992) 2.76
Structure and assembly of coated vesicles. Annu Rev Biophys Biophys Chem (1987) 2.65
The yeast Pan2 protein is required for poly(A)-binding protein-stimulated poly(A)-nuclease activity. J Biol Chem (1996) 2.62
Genetic and biochemical characterization of clathrin-deficient Saccharomyces cerevisiae. Mol Cell Biol (1987) 2.50
DNM1, a dynamin-related gene, participates in endosomal trafficking in yeast. J Cell Biol (1995) 2.46
A test of clathrin function in protein secretion and cell growth. Science (1985) 2.36
Alteration of a yeast SH3 protein leads to conditional viability with defects in cytoskeletal and budding patterns. Mol Cell Biol (1993) 2.23
Clathrin facilitates the internalization of seven transmembrane segment receptors for mating pheromones in yeast. J Cell Biol (1993) 2.14
Disruption of genes encoding subunits of yeast vacuolar H(+)-ATPase causes conditional lethality. Proc Natl Acad Sci U S A (1990) 2.14
The emergence of clathrin-independent pinocytic pathways. Curr Opin Cell Biol (1995) 2.12
The tyrosine kinase substrate eps15 is constitutively associated with the plasma membrane adaptor AP-2. J Cell Biol (1995) 2.06
Role of type I myosins in receptor-mediated endocytosis in yeast. Science (1996) 2.03
The ear of alpha-adaptin interacts with the COOH-terminal domain of the Eps 15 protein. J Biol Chem (1996) 1.93
A protein-binding domain, EH, identified in the receptor tyrosine kinase substrate Eps15 and conserved in evolution. Proc Natl Acad Sci U S A (1995) 1.87
Multiple classes of yeast mutants are defective in vacuole partitioning yet target vacuole proteins correctly. Mol Biol Cell (1996) 1.83
Actin cytoskeleton and budding pattern are altered in the yeast rvs161 mutant: the Rvs161 protein shares common domains with the brain protein amphiphysin. Mol Gen Genet (1995) 1.78
Regulating the HO endonuclease in yeast. Curr Opin Genet Dev (1993) 1.73
The EH-domain-containing protein Pan1 is required for normal organization of the actin cytoskeleton in Saccharomyces cerevisiae. Mol Cell Biol (1996) 1.69
Transit of epidermal growth factor through coated pits of the Golgi system. J Cell Biol (1982) 1.66
Cytosol- and clathrin-dependent stimulation of endocytosis in vitro by purified adaptors. J Cell Biol (1992) 1.63
An immunophilin that binds M(r) 90,000 heat shock protein: main structural features of a mammalian p59 protein. Proc Natl Acad Sci U S A (1992) 1.56
Pathways followed by membrane recovered from the surface of plasma cells and myeloma cells. J Exp Med (1980) 1.55
Calcium-independent calmodulin requirement for endocytosis in yeast. EMBO J (1994) 1.45
Endocytosis without clathrin. Trends Cell Biol (1994) 1.39
Isolation of vacuolar membrane H(+)-ATPase-deficient yeast mutants; the VMA5 and VMA4 genes are essential for assembly and activity of the vacuolar H(+)-ATPase. J Biol Chem (1993) 1.37
The SH3 domain of Crk binds specifically to a conserved proline-rich motif in Eps15 and Eps15R. J Biol Chem (1995) 1.36
Identification of coated vesicles in Saccharomyces cerevisiae. J Cell Biol (1984) 1.28
Mutations altering the mitochondrial-cytoplasmic distribution of Mod5p implicate the actin cytoskeleton and mRNA 3' ends and/or protein synthesis in mitochondrial delivery. Mol Cell Biol (1995) 1.26
Receptor signalling and the regulation of endocytic membrane transport. Curr Opin Cell Biol (1996) 1.25
Characterization of yeast clathrin and anticlathrin heavy-chain monoclonal antibodies. J Cell Biochem (1988) 1.22
Transferrin uptake and release by reticulocytes treated with proteolytic enzymes and neuraminidase. Biochim Biophys Acta (1976) 1.19
Kinetics of histone endocytosis in Chinese hamster ovary cells. A flow cytofluorometric analysis. J Biol Chem (1982) 1.05
Nucleotide sequence and analysis of the centromeric region of yeast chromosome IX. Yeast (1995) 0.93
Isolation by fluorescence-activated cell sorting of Chinese hamster ovary cell lines with pleiotropic, temperature-conditional defects in receptor recycling. J Biol Chem (1991) 0.86
Use of electron-opaque tracers for studies on endocytosis and membrane recycling. Methods Enzymol (1983) 0.83
A heat shock gene from Saccharomyces cerevisiae encoding a secretory glycoprotein. Proc Natl Acad Sci U S A (1992) 0.81
Fluorescent indicators for Ca2+ based on green fluorescent proteins and calmodulin. Nature (1997) 18.83
Autophagy as a regulated pathway of cellular degradation. Science (2000) 17.27
Protein sorting in Saccharomyces cerevisiae: isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolases. Mol Cell Biol (1988) 13.27
A new vital stain for visualizing vacuolar membrane dynamics and endocytosis in yeast. J Cell Biol (1995) 12.18
Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I. Cell (2001) 9.08
Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting. Science (1993) 7.86
The Vps4p AAA ATPase regulates membrane association of a Vps protein complex required for normal endosome function. EMBO J (1998) 7.68
The fungal vacuole: composition, function, and biogenesis. Microbiol Rev (1990) 6.98
Measurement of cytosolic, mitochondrial, and Golgi pH in single living cells with green fluorescent proteins. Proc Natl Acad Sci U S A (1998) 6.73
Coatomer is essential for retrieval of dilysine-tagged proteins to the endoplasmic reticulum. Cell (1994) 6.57
Suppressor mutations that restore export of a protein with a defective signal sequence. Cell (1981) 6.33
The dynamin-related GTPase Dnm1 regulates mitochondrial fission in yeast. Nat Cell Biol (1999) 6.26
Mechanisms of protein localization. Microbiol Rev (1983) 6.12
Fab1p PtdIns(3)P 5-kinase function essential for protein sorting in the multivesicular body. Cell (1998) 6.07
Distinct sequence determinants direct intracellular sorting and modification of a yeast vacuolar protease. Cell (1987) 5.92
Dnm1p GTPase-mediated mitochondrial fission is a multi-step process requiring the novel integral membrane component Fis1p. J Cell Biol (2000) 5.86
Compartmental organization of Golgi-specific protein modification and vacuolar protein sorting events defined in a yeast sec18 (NSF) mutant. J Cell Biol (1991) 5.76
Isolation of yeast mutants defective in protein targeting to the vacuole. Proc Natl Acad Sci U S A (1986) 5.71
Intracellular sorting and processing of a yeast vacuolar hydrolase: proteinase A propeptide contains vacuolar targeting information. Mol Cell Biol (1988) 5.42
Characterization of VPS34, a gene required for vacuolar protein sorting and vacuole segregation in Saccharomyces cerevisiae. Mol Cell Biol (1990) 5.25
Membrane protein sorting: biosynthesis, transport and processing of yeast vacuolar alkaline phosphatase. EMBO J (1989) 5.12
The sorting receptor for yeast vacuolar carboxypeptidase Y is encoded by the VPS10 gene. Cell (1994) 5.10
Endosomal transport function in yeast requires a novel AAA-type ATPase, Vps4p. EMBO J (1997) 5.05
Organelle assembly in yeast: characterization of yeast mutants defective in vacuolar biogenesis and protein sorting. J Cell Biol (1988) 4.90
Multilamellar endosome-like compartment accumulates in the yeast vps28 vacuolar protein sorting mutant. Mol Biol Cell (1996) 4.71
Novel syntaxin homologue, Pep12p, required for the sorting of lumenal hydrolases to the lysosome-like vacuole in yeast. Mol Biol Cell (1996) 4.58
A membrane coat complex essential for endosome-to-Golgi retrograde transport in yeast. J Cell Biol (1998) 4.41
Mammalian tumor susceptibility gene 101 (TSG101) and the yeast homologue, Vps23p, both function in late endosomal trafficking. Traffic (2000) 4.17
A multispecificity syntaxin homologue, Vam3p, essential for autophagic and biosynthetic protein transport to the vacuole. J Cell Biol (1997) 4.16
Phosphoinositides as regulators in membrane traffic. Science (1996) 4.13
The amino terminus of the yeast F1-ATPase beta-subunit precursor functions as a mitochondrial import signal. J Cell Biol (1986) 4.07
Phosphatidylinositol(3)-phosphate signaling mediated by specific binding to RING FYVE domains. Mol Cell (1998) 4.01
An MF alpha 1-SUC2 (alpha-factor-invertase) gene fusion for study of protein localization and gene expression in yeast. Proc Natl Acad Sci U S A (1983) 3.95
Characterization of a component of the yeast secretion machinery: identification of the SEC18 gene product. Mol Cell Biol (1988) 3.74
New component of the vacuolar class C-Vps complex couples nucleotide exchange on the Ypt7 GTPase to SNARE-dependent docking and fusion. J Cell Biol (2000) 3.69
Mutations affecting localization of an Escherichia coli outer membrane protein, the bacteriophage lambda receptor. J Mol Biol (1980) 3.62
Endosome to Golgi retrieval of the vacuolar protein sorting receptor, Vps10p, requires the function of the VPS29, VPS30, and VPS35 gene products. J Cell Biol (1997) 3.61
The role of phosphoinositides in membrane transport. Curr Opin Cell Biol (2001) 3.57
The Saccharomyces cerevisiae SEC14 gene encodes a cytosolic factor that is required for transport of secretory proteins from the yeast Golgi complex. J Cell Biol (1989) 3.55
A membrane-associated complex containing the Vps15 protein kinase and the Vps34 PI 3-kinase is essential for protein sorting to the yeast lysosome-like vacuole. EMBO J (1993) 3.49
Sequence analysis of mutations that prevent export of lambda receptor, an Escherichia coli outer membrane protein. Nature (1980) 3.36
Signal-mediated retrieval of a membrane protein from the Golgi to the ER in yeast. J Cell Biol (1994) 3.32
The AP-3 adaptor complex is essential for cargo-selective transport to the yeast vacuole. Cell (1997) 3.30
Class C Vps protein complex regulates vacuolar SNARE pairing and is required for vesicle docking/fusion. Mol Cell (2000) 3.30
A novel RING finger protein complex essential for a late step in protein transport to the yeast vacuole. Mol Biol Cell (1997) 3.27
Yeast vacuolar proenzymes are sorted in the late Golgi complex and transported to the vacuole via a prevacuolar endosome-like compartment. J Cell Biol (1993) 3.25
Vesicular stomatitis virus glycoprotein is sorted and concentrated during export from the endoplasmic reticulum. Cell (1994) 3.25
Fab1p is essential for PtdIns(3)P 5-kinase activity and the maintenance of vacuolar size and membrane homeostasis. J Cell Biol (1998) 3.24
Vesicle-mediated protein transport: regulatory interactions between the Vps15 protein kinase and the Vps34 PtdIns 3-kinase essential for protein sorting to the vacuole in yeast. J Cell Biol (1995) 3.16
Phox domain interaction with PtdIns(3)P targets the Vam7 t-SNARE to vacuole membranes. Nat Cell Biol (2001) 3.14
The dynamin-related GTPase, Mgm1p, is an intermembrane space protein required for maintenance of fusion competent mitochondria. J Cell Biol (2000) 3.14
Intracellular targeting and import of an F1-ATPase beta-subunit-beta-galactosidase hybrid protein into yeast mitochondria. Proc Natl Acad Sci U S A (1984) 3.02
Receptor-mediated protein sorting to the vacuole in yeast: roles for a protein kinase, a lipid kinase and GTP-binding proteins. Annu Rev Cell Dev Biol (1995) 2.93
A mechanism of protein localization: the signal hypothesis and bacteria. J Cell Biol (1980) 2.91
VPS21 encodes a rab5-like GTP binding protein that is required for the sorting of yeast vacuolar proteins. EMBO J (1994) 2.90
Distinct roles for the yeast phosphatidylinositol 4-kinases, Stt4p and Pik1p, in secretion, cell growth, and organelle membrane dynamics. Mol Biol Cell (2000) 2.87
Localization and processing of outer membrane and periplasmic proteins in Escherichia coli strains harboring export-specific suppressor mutations. J Biol Chem (1982) 2.85
A previously unidentified gene in the spc operon of Escherichia coli K12 specifies a component of the protein export machinery. Cell (1982) 2.84
Vam7p, a SNAP-25-like molecule, and Vam3p, a syntaxin homolog, function together in yeast vacuolar protein trafficking. Mol Cell Biol (1998) 2.80
Cytoplasm to vacuole trafficking of aminopeptidase I requires a t-SNARE-Sec1p complex composed of Tlg2p and Vps45p. EMBO J (1999) 2.77
Role for phosphatidylinositol 3-kinase in the sorting and transport of newly synthesized lysosomal enzymes in mammalian cells. J Cell Biol (1995) 2.74
Phosphoinositide signaling and the regulation of membrane trafficking in yeast. Trends Biochem Sci (2000) 2.72
Vps34p required for yeast vacuolar protein sorting is a multiple specificity kinase that exhibits both protein kinase and phosphatidylinositol-specific PI 3-kinase activities. J Biol Chem (1994) 2.66
Novel PI(4)P 5-kinase homologue, Fab1p, essential for normal vacuole function and morphology in yeast. Mol Biol Cell (1995) 2.64
A novel protein kinase homolog essential for protein sorting to the yeast lysosome-like vacuole. Cell (1991) 2.64
Mutations in the VPS45 gene, a SEC1 homologue, result in vacuolar protein sorting defects and accumulation of membrane vesicles. J Cell Sci (1994) 2.61
Novel Golgi to vacuole delivery pathway in yeast: identification of a sorting determinant and required transport component. EMBO J (1997) 2.60
The cytoplasmic tail domain of the vacuolar protein sorting receptor Vps10p and a subset of VPS gene products regulate receptor stability, function, and localization. Mol Biol Cell (1995) 2.50
The VPS16 gene product associates with a sedimentable protein complex and is essential for vacuolar protein sorting in yeast. J Biol Chem (1993) 2.50
Pan1p, yeast eps15, functions as a multivalent adaptor that coordinates protein-protein interactions essential for endocytosis. J Cell Biol (1998) 2.43
A putative zinc finger protein, Saccharomyces cerevisiae Vps18p, affects late Golgi functions required for vacuolar protein sorting and efficient alpha-factor prohormone maturation. Mol Cell Biol (1991) 2.38
Mutations altering the cellular localization of the phage lambda receptor, an Escherichia coli outer membrane protein. Proc Natl Acad Sci U S A (1978) 2.37
Telomerase reverse transcriptase gene is a direct target of c-Myc but is not functionally equivalent in cellular transformation. Oncogene (1999) 2.34
Characterization of yeast Vps33p, a protein required for vacuolar protein sorting and vacuole biogenesis. Mol Cell Biol (1990) 2.32
ARF is required for maintenance of yeast Golgi and endosome structure and function. Mol Biol Cell (1998) 2.32
Alternative pathways for the sorting of soluble vacuolar proteins in yeast: a vps35 null mutant missorts and secretes only a subset of vacuolar hydrolases. Mol Biol Cell (1992) 2.32
GAL2 codes for a membrane-bound subunit of the galactose permease in Saccharomyces cerevisiae. J Bacteriol (1986) 2.30
Mmm1p, a mitochondrial outer membrane protein, is connected to mitochondrial DNA (mtDNA) nucleoids and required for mtDNA stability. J Cell Biol (2001) 2.28
A novel Sec18p/NSF-dependent complex required for Golgi-to-endosome transport in yeast. Mol Biol Cell (1997) 2.24
Resistin is not associated with insulin sensitivity or the metabolic syndrome in humans. Diabetologia (2005) 2.23
Mutants of Saccharomyces cerevisiae that block intervacuole vesicular traffic and vacuole division and segregation. Proc Natl Acad Sci U S A (1990) 2.18
Yeast epsins contain an essential N-terminal ENTH domain, bind clathrin and are required for endocytosis. EMBO J (1999) 2.18
Division of mitochondria requires a novel DMN1-interacting protein, Net2p. Mol Biol Cell (2001) 2.17
COPI-independent anterograde transport: cargo-selective ER to Golgi protein transport in yeast COPI mutants. J Cell Biol (1997) 2.16
Vac1p coordinates Rab and phosphatidylinositol 3-kinase signaling in Vps45p-dependent vesicle docking/fusion at the endosome. Curr Biol (1999) 2.15
A sorting nexin-1 homologue, Vps5p, forms a complex with Vps17p and is required for recycling the vacuolar protein-sorting receptor. Mol Biol Cell (1997) 2.14
Protein traffic in the yeast endocytic and vacuolar protein sorting pathways. Curr Opin Cell Biol (1998) 2.13
COPII vesicles derived from mammalian endoplasmic reticulum microsomes recruit COPI. J Cell Biol (1996) 2.11
Drosophila roadblock and Chlamydomonas LC7: a conserved family of dynein-associated proteins involved in axonal transport, flagellar motility, and mitosis. J Cell Biol (1999) 2.09
Location, location, location: membrane targeting directed by PX domains. Science (2001) 2.09
Sac1 lipid phosphatase and Stt4 phosphatidylinositol 4-kinase regulate a pool of phosphatidylinositol 4-phosphate that functions in the control of the actin cytoskeleton and vacuole morphology. Mol Biol Cell (2001) 1.99
Importance of secondary structure in the signal sequence for protein secretion. Proc Natl Acad Sci U S A (1983) 1.98
Fatal embryonic bleeding events in mice lacking tissue factor, the cell-associated initiator of blood coagulation. Proc Natl Acad Sci U S A (1996) 1.93
A genetic and structural analysis of the yeast Vps15 protein kinase: evidence for a direct role of Vps15p in vacuolar protein delivery. EMBO J (1991) 1.93
The AP-3 complex: a coat of many colours. Trends Cell Biol (1998) 1.92
Invertase beta-galactosidase hybrid proteins fail to be transported from the endoplasmic reticulum in Saccharomyces cerevisiae. Mol Cell Biol (1984) 1.91
D-ribose metabolism in Escherichia coli K-12: genetics, regulation, and transport. J Bacteriol (1984) 1.89