Cloning and characterization of two Toll/Interleukin-1 receptor-like genes TIL3 and TIL4: evidence for a multi-gene receptor family in humans.

PubWeight™: 2.33‹?› | Rank: Top 2%

🔗 View Article (PMID 9596645)

Published in Blood on June 01, 1998

Authors

P M Chaudhary1, C Ferguson, V Nguyen, O Nguyen, H F Massa, M Eby, A Jasmin, B J Trask, L Hood, P S Nelson

Author Affiliations

1: Department of Medicine and Molecular Biotechnology, University of Washington, Seattle, WA 98195, USA.

Articles citing this

The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors. Proc Natl Acad Sci U S A (2000) 9.67

MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4. J Exp Med (1999) 9.23

Toll-like receptor-2 mediates mycobacteria-induced proinflammatory signaling in macrophages. Proc Natl Acad Sci U S A (1999) 4.49

Human toll-like receptor 2 confers responsiveness to bacterial lipopolysaccharide. J Exp Med (1998) 4.17

Herpes simplex virus 1 interaction with Toll-like receptor 2 contributes to lethal encephalitis. Proc Natl Acad Sci U S A (2004) 3.74

TLR2 is expressed on activated T cells as a costimulatory receptor. Proc Natl Acad Sci U S A (2004) 3.04

Toll receptor-mediated Drosophila immune response requires Dif, an NF-kappaB factor. Genes Dev (1999) 2.64

Role of Toll-like receptors in pathogen recognition. Clin Microbiol Rev (2003) 2.59

Inducible expression of human beta-defensin 2 by Fusobacterium nucleatum in oral epithelial cells: multiple signaling pathways and role of commensal bacteria in innate immunity and the epithelial barrier. Infect Immun (2000) 2.55

Toll-related receptors and the control of antimicrobial peptide expression in Drosophila. Proc Natl Acad Sci U S A (2000) 2.45

Toll, a new piece in the puzzle of innate immunity. J Exp Med (1999) 2.36

ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway. Genes Dev (1999) 2.17

Intact gram-negative Helicobacter pylori, Helicobacter felis, and Helicobacter hepaticus bacteria activate innate immunity via toll-like receptor 2 but not toll-like receptor 4. Infect Immun (2004) 1.72

Cytosolic signaling protein Ecsit also localizes to mitochondria where it interacts with chaperone NDUFAF1 and functions in complex I assembly. Genes Dev (2007) 1.53

Hepatitis C virus induces toll-like receptor 4 expression, leading to enhanced production of beta interferon and interleukin-6. J Virol (2006) 1.38

Role of innate immune factors in the adjuvant activity of monophosphoryl lipid A. Infect Immun (2003) 1.37

Differential constitutive and cytokine-modulated expression of human Toll-like receptors in primary neutrophils, monocytes, and macrophages. Int J Med Sci (2008) 1.24

Structural study of binding of flagellin by Toll-like receptor 5. J Bacteriol (2003) 1.19

Membrane-associated proteins of a lipopolysaccharide-deficient mutant of Neisseria meningitidis activate the inflammatory response through toll-like receptor 2. Infect Immun (2001) 1.11

Oral inflammatory diseases and systemic inflammation: role of the macrophage. Front Immunol (2012) 1.07

Role of Toll-like receptors in health and diseases of gastrointestinal tract. World J Gastroenterol (2006) 1.06

TLR4-mediated activation of dendritic cells by the heat shock protein DnaK from Francisella tularensis. J Leukoc Biol (2008) 1.01

Bench-to-bedside review: Toll-like receptors and their role in septic shock. Crit Care (2002) 1.01

Toll-like receptor triggering in cord blood mesenchymal stem cells. J Cell Mol Med (2009) 0.92

Anti-CD14 monoclonal antibodies inhibit the production of tumor necrosis factor alpha and interleukin-10 by human monocytes stimulated with killed and live Haemophilus influenzae or Streptococcus pneumoniae organisms. Infect Immun (1999) 0.90

Toward a modern synthesis of immunity: Charles A. Janeway Jr. and the immunologist's dirty little secret. Yale J Biol Med (2011) 0.87

A toll for T cell costimulation. Ann Rheum Dis (2004) 0.86

The involvement of the Toll-like receptor family in ovulation. J Assist Reprod Genet (2008) 0.85

Toll-like receptors 2 and 4 and their mutations in patients with otitis media and middle ear effusion. Clin Exp Otorhinolaryngol (2008) 0.85

Toll-like receptor 4 (TLR4) and typhoid fever in Vietnam. PLoS One (2009) 0.80

Moesin-induced signaling in response to lipopolysaccharide in macrophages. J Periodontal Res (2010) 0.77

Evolution of an intronic microsatellite polymorphism in Toll-like receptor 2 among primates. Immunogenetics (2006) 0.75

Molecular characterization and analysis of TLR-1 in rabbit tissues. Cent Eur J Immunol (2016) 0.75

Epigenetics and innate immunity: the 'unTolld' story. Immunol Cell Biol (2016) 0.75

Articles by these authors

Initial sequencing and analysis of the human genome. Nature (2001) 212.86

A common language for physical mapping of the human genome. Science (1989) 17.36

Integrated genomic and proteomic analyses of a systematically perturbed metabolic network. Science (2001) 17.11

A physical map of the human genome. Nature (2001) 12.39

Segmental duplications: organization and impact within the current human genome project assembly. Genome Res (2001) 11.77

Integration of cytogenetic landmarks into the draft sequence of the human genome. Nature (2001) 10.96

An immunoglobulin heavy chain variable region gene is generated from three segments of DNA: VH, D and JH. Cell (1980) 10.35

Two mRNAs can be produced from a single immunoglobulin mu gene by alternative RNA processing pathways. Cell (1980) 9.86

DNA diagnostics--molecular techniques and automation. Science (1988) 8.85

Gene families: the taxonomy of protein paralogs and chimeras. Science (1997) 8.80

DNA duplication associated with Charcot-Marie-Tooth disease type 1A. Cell (1991) 7.93

A new approach to decoding life: systems biology. Annu Rev Genomics Hum Genet (2001) 7.79

A ligase-mediated gene detection technique. Science (1988) 7.61

Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1. Nat Genet (1997) 6.66

Two mRNAs with different 3' ends encode membrane-bound and secreted forms of immunoglobulin mu chain. Cell (1980) 6.32

A single VH gene segment encodes the immune response to phosphorylcholine: somatic mutation is correlated with the class of the antibody. Cell (1981) 5.87

Genome sequence of Halobacterium species NRC-1. Proc Natl Acad Sci U S A (2000) 5.87

The organization, expression, and evolution of antibody genes and other multigene families. Annu Rev Genet (1975) 5.87

A pseudogene homologous to mouse transplantation antigens: transplantation antigens are encoded by eight exons that correlate with protein domains. Cell (1981) 5.43

A molecular map of the immune response region from the major histocompatibility complex of the mouse. Nature (1982) 5.12

Three cDNA clones encoding mouse transplantation antigens: homology to immunoglobulin genes. Cell (1981) 4.95

Pairwise end sequencing: a unified approach to genomic mapping and sequencing. Genomics (1995) 4.83

Clusters of genes encoding mouse transplantation antigens. Cell (1982) 4.71

Antibody diversity: somatic hypermutation of rearranged VH genes. Cell (1981) 4.65

A new strategy for genome sequencing. Nature (1996) 4.61

Transgenic mice that express a myelin basic protein-specific T cell receptor develop spontaneous autoimmunity. Cell (1993) 4.59

Restricted use of T cell receptor V genes in murine autoimmune encephalomyelitis raises possibilities for antibody therapy. Cell (1988) 4.47

Genes of the major histocompatibility complex of the mouse. Annu Rev Immunol (1983) 4.44

An immunoglobulin heavy-chain gene is formed by at least two recombinational events. Nature (1980) 3.99

Striking sequence similarity over almost 100 kilobases of human and mouse T-cell receptor DNA. Nat Genet (1994) 3.88

IgG antibodies to phosphorylcholine exhibit more diversity than their IgM counterparts. Nature (1981) 3.86

Prostate-localized and androgen-regulated expression of the membrane-bound serine protease TMPRSS2. Cancer Res (1999) 3.79

Silkmoth chorion proteins: sequence analysis of the products of a multigene family. Proc Natl Acad Sci U S A (1978) 3.60

Structural studies of the scrapie prion protein using mass spectrometry and amino acid sequencing. Biochemistry (1993) 3.54

Introduced T cell receptor variable region gene segments recombine in pre-B cells: evidence that B and T cells use a common recombinase. Cell (1986) 3.51

Large-scale and automated DNA sequence determination. Science (1991) 3.45

Cell-type-specific cDNA probes and the murine I region: the localization and orientation of Ad alpha. Proc Natl Acad Sci U S A (1984) 3.43

Evidence for the organization of chromatin in megabase pair-sized loops arranged along a random walk path in the human G0/G1 interphase nucleus. J Cell Biol (1995) 3.42

The human T cell antigen receptor is encoded by variable, diversity, and joining gene segments that rearrange to generate a complete V gene. Cell (1984) 3.41

Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway. Immunity (1997) 3.33

T cell antigen receptors and the immunoglobulin supergene family. Cell (1985) 3.23

Cell-cell interaction in prostate gene regulation and cytodifferentiation. Proc Natl Acad Sci U S A (1997) 3.22

Immunoglobulin heavy chain gene organization in mice: analysis of a myeloma genomic clone containing variable and alpha constant regions. Proc Natl Acad Sci U S A (1979) 3.19

The structure, rearrangement and expression of D beta gene segments of the murine T-cell antigen receptor. Nature (1984) 3.18

DNA sequence of a gene encoding a BALB/c mouse Ld transplantation antigen. Science (1982) 3.17

PATRIC: the VBI PathoSystems Resource Integration Center. Nucleic Acids Res (2006) 3.06

Mechanism of antibody diversity: germ line basis for variability. Science (1970) 3.05

Predominant use of a V alpha gene segment in mouse T-cell receptors for cytochrome c. Nature (1987) 2.99

Understanding the adaptation of Halobacterium species NRC-1 to its extreme environment through computational analysis of its genome sequence. Genome Res (2001) 2.92

Multidrug efflux pump AcrAB of Salmonella typhimurium excretes only those beta-lactam antibiotics containing lipophilic side chains. J Bacteriol (1998) 2.92

Complete genomic sequence and analysis of 117 kb of human DNA containing the gene BRCA1. Genome Res (1996) 2.91

Automated DNA diagnostics using an ELISA-based oligonucleotide ligation assay. Proc Natl Acad Sci U S A (1990) 2.88

Genes of the major histocompatibility complex in mouse and man. Science (1983) 2.88

Rearrangement of genetic information may produce immunoglobulin diversity. Nature (1979) 2.84

Human lysozyme gene mutations cause hereditary systemic amyloidosis. Nature (1993) 2.78

Mechanism of antibody synthesis: size differences between mouse kappa chains. Science (1967) 2.77

Zinc-dependent structure of a single-finger domain of yeast ADR1. Science (1988) 2.76

DNA sequence determination by hybridization: a strategy for efficient large-scale sequencing. Science (1993) 2.76

Estimating genomic distance from DNA sequence location in cell nuclei by a random walk model. Science (1992) 2.69

From hematopoiesis to neuropoiesis: evidence of overlapping genetic programs. Proc Natl Acad Sci U S A (2001) 2.66

Project normal: defining normal variance in mouse gene expression. Proc Natl Acad Sci U S A (2001) 2.66

Dynorphin-(1-13), an extraordinarily potent opioid peptide. Proc Natl Acad Sci U S A (1979) 2.66

The complete 685-kilobase DNA sequence of the human beta T cell receptor locus. Science (1996) 2.62

Mouse Cmu heavy chain immunoglobulin gene segment contains three intervening sequences separating domains. Nature (1980) 2.52

Separate elements control DJ and VDJ rearrangement in a transgenic recombination substrate. EMBO J (1990) 2.52

Identification of the class I genes of the mouse major histocompatibility complex by DNA-mediated gene transfer. Nature (1982) 2.48

Determining cause of death in prostate cancer: are death certificates valid? J Natl Cancer Inst (2001) 2.46

Comparative hybridization of an array of 21,500 ovarian cDNAs for the discovery of genes overexpressed in ovarian carcinomas. Gene (1999) 2.45

Messenger RNA translation state: the second dimension of high-throughput expression screening. Proc Natl Acad Sci U S A (1999) 2.42

Mouse c-myc oncogene is located on chromosome 15 and translocated to chromosome 12 in plasmacytomas. Science (1982) 2.40

Genomic organization of the genes encoding mouse T-cell receptor alpha-chain. Nature (1985) 2.40

Direct evidence for chromosomal inversion during T-cell receptor beta-gene rearrangements. Nature (1986) 2.33

Rearrangement and transcription of the beta-chain genes of the T-cell antigen receptor in different types of murine lymphocytes. Nature (1985) 2.29

Expression of a myelin basic protein gene in transgenic shiverer mice: correction of the dysmyelinating phenotype. Cell (1987) 2.29

The laryngeal mask airway in pediatric radiotherapy. Anesthesiology (1990) 2.29

The joining of V and J gene segments creates antibody diversity. Nature (1980) 2.28

The human homolog of rat Jagged1 expressed by marrow stroma inhibits differentiation of 32D cells through interaction with Notch1. Immunity (1998) 2.23

Modulation of the NF-kappa B pathway by virally encoded death effector domains-containing proteins. Oncogene (1999) 2.21

Diversity and structure of human T-cell receptor beta-chain variable region genes. Proc Natl Acad Sci U S A (1986) 2.19

Mice devoid of gamma-aminobutyrate type A receptor beta3 subunit have epilepsy, cleft palate, and hypersensitive behavior. Proc Natl Acad Sci U S A (1997) 2.16

Rearranged beta T cell receptor genes in a helper T cell clone specific for lysozyme: no correlation between V beta and MHC restriction. Cell (1985) 2.14

Systems cancer medicine: towards realization of predictive, preventive, personalized and participatory (P4) medicine. J Intern Med (2012) 2.13

Gene transfer of H-2 class II genes: antigen presentation by mouse fibroblast and hamster B-cell lines. Cell (1984) 2.12

Nucleotide sequence of a light chain gene of the mouse I-A subregion: A beta d. Science (1983) 2.12

Evidence for a rare prostate cancer-susceptibility locus at chromosome 1p36. Am J Hum Genet (1999) 2.12

Isolation and characterization of the cDNA encoding human DNA methyltransferase. Nucleic Acids Res (1992) 2.10

The gene for the peripheral myelin protein PMP-22 is a candidate for Charcot-Marie-Tooth disease type 1A. Nat Genet (1992) 2.08

Stimulation of p53-mediated transcriptional activation by the p53-binding proteins, 53BP1 and 53BP2. J Biol Chem (1998) 2.07

Modeling the feasibility of whole genome shotgun sequencing using a pairwise end strategy. Genomics (2000) 2.05