Published in Nat Genet on May 01, 1994
PipMaker--a web server for aligning two genomic DNA sequences. Genome Res (2000) 17.46
Estimate of the mutation rate per nucleotide in humans. Genetics (2000) 15.08
Covariation in frequencies of substitution, deletion, transposition, and recombination during eutherian evolution. Genome Res (2003) 11.12
Human and mouse gene structure: comparative analysis and application to exon prediction. Genome Res (2000) 8.28
Active conservation of noncoding sequences revealed by three-way species comparisons. Genome Res (2000) 6.18
Genome rearrangements in mammalian evolution: lessons from human and mouse genomes. Genome Res (2003) 5.22
Comparative analysis of noncoding regions of 77 orthologous mouse and human gene pairs. Genome Res (1999) 4.50
Colinearity and its exceptions in orthologous adh regions of maize and sorghum. Proc Natl Acad Sci U S A (1999) 3.60
Computational prediction of transcription-factor binding site locations. Genome Biol (2003) 3.39
An invariant T cell receptor alpha chain defines a novel TAP-independent major histocompatibility complex class Ib-restricted alpha/beta T cell subpopulation in mammals. J Exp Med (1999) 3.20
Leveraging the mouse genome for gene prediction in human: from whole-genome shotgun reads to a global synteny map. Genome Res (2003) 3.18
Genome sequence of Haloarcula marismortui: a halophilic archaeon from the Dead Sea. Genome Res (2004) 2.75
Comparative DNA sequence analysis of mouse and human protocadherin gene clusters. Genome Res (2001) 2.66
Statistical significance of clusters of motifs represented by position specific scoring matrices in nucleotide sequences. Nucleic Acids Res (2002) 2.30
CoreGenes: a computational tool for identifying and cataloging "core" genes in a set of small genomes. BMC Bioinformatics (2002) 2.13
Generation and comparative analysis of approximately 3.3 Mb of mouse genomic sequence orthologous to the region of human chromosome 7q11.23 implicated in Williams syndrome. Genome Res (2002) 1.80
Human and mouse alpha-synuclein genes: comparative genomic sequence analysis and identification of a novel gene regulatory element. Genome Res (2001) 1.65
Quantitative and qualitative changes in V-J alpha rearrangements during mouse thymocytes differentiation: implication for a limited T cell receptor alpha chain repertoire. J Exp Med (2002) 1.62
Comparative genomic analysis as a tool for biological discovery. J Physiol (2004) 1.61
Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse. Genome Res (2003) 1.32
Comparative genomic sequence analysis of the human and mouse cystic fibrosis transmembrane conductance regulator genes. Proc Natl Acad Sci U S A (2000) 1.19
Sequence conservation at human and mouse orthologous common fragile regions, FRA3B/FHIT and Fra14A2/Fhit. Proc Natl Acad Sci U S A (2001) 1.15
Diagnostic role of tests for T cell receptor (TCR) genes. J Clin Pathol (2003) 1.14
Comparative genome sequence analysis of the Bpa/Str region in mouse and Man. Genome Res (2000) 1.13
Comparative genomic tools and databases: providing insights into the human genome. J Clin Invest (2003) 1.10
Mapping the mouse genome: current status and future prospects. Proc Natl Acad Sci U S A (1995) 1.08
Insights from human/mouse genome comparisons. Mamm Genome (2003) 1.06
Genomic structure around joining segments and constant regions of swine T-cell receptor alpha/delta (TRA/TRD) locus. Immunology (2003) 1.03
Characterization of clustered MHC-linked olfactory receptor genes in human and mouse. Genome Res (2001) 1.02
TCRalpha enhancer activation occurs via a conformational change of a pre-assembled nucleo-protein complex. EMBO J (2000) 0.94
lir-2, lir-1 and lin-26 encode a new class of zinc-finger proteins and are organized in two overlapping operons both in Caenorhabditis elegans and in Caenorhabditis briggsae. Genetics (1999) 0.93
A targeted mutation at the T-cell receptor alpha/delta locus impairs T-cell development and reveals the presence of the nearby antiapoptosis gene Dad1. Mol Cell Biol (1997) 0.89
Unique profile of ordered arrangements of repetitive elements in the C57BL/6J mouse genome implicating their functional roles. PLoS One (2012) 0.88
Cloning and functional characterization of the 5'-flanking region of the human bone morphogenetic protein-2 gene. Biochem J (1999) 0.86
A conserved sequence block in murine and human T cell receptor (TCR) Jalpha region is a composite element that enhances TCR alpha enhancer activity and binds multiple nuclear factors. Proc Natl Acad Sci U S A (1998) 0.85
Pufferfish and new paradigm for comparative genome analysis. Proc Natl Acad Sci U S A (1996) 0.84
Conservation anchors in the vertebrate genome. Genome Biol (2005) 0.82
The role of the laboratory mouse in the human genome project. Am J Hum Genet (1996) 0.75
Initial sequencing and analysis of the human genome. Nature (2001) 212.86
A common language for physical mapping of the human genome. Science (1989) 17.36
Integrated genomic and proteomic analyses of a systematically perturbed metabolic network. Science (2001) 17.11
A physical map of the human genome. Nature (2001) 12.39
An immunoglobulin heavy chain variable region gene is generated from three segments of DNA: VH, D and JH. Cell (1980) 10.35
Two mRNAs can be produced from a single immunoglobulin mu gene by alternative RNA processing pathways. Cell (1980) 9.86
DNA diagnostics--molecular techniques and automation. Science (1988) 8.85
Gene families: the taxonomy of protein paralogs and chimeras. Science (1997) 8.80
A new approach to decoding life: systems biology. Annu Rev Genomics Hum Genet (2001) 7.79
A ligase-mediated gene detection technique. Science (1988) 7.61
Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1. Nat Genet (1997) 6.66
Two mRNAs with different 3' ends encode membrane-bound and secreted forms of immunoglobulin mu chain. Cell (1980) 6.32
A single VH gene segment encodes the immune response to phosphorylcholine: somatic mutation is correlated with the class of the antibody. Cell (1981) 5.87
Genome sequence of Halobacterium species NRC-1. Proc Natl Acad Sci U S A (2000) 5.87
The organization, expression, and evolution of antibody genes and other multigene families. Annu Rev Genet (1975) 5.87
A pseudogene homologous to mouse transplantation antigens: transplantation antigens are encoded by eight exons that correlate with protein domains. Cell (1981) 5.43
A molecular map of the immune response region from the major histocompatibility complex of the mouse. Nature (1982) 5.12
Three cDNA clones encoding mouse transplantation antigens: homology to immunoglobulin genes. Cell (1981) 4.95
Pairwise end sequencing: a unified approach to genomic mapping and sequencing. Genomics (1995) 4.83
Clusters of genes encoding mouse transplantation antigens. Cell (1982) 4.71
Antibody diversity: somatic hypermutation of rearranged VH genes. Cell (1981) 4.65
A new strategy for genome sequencing. Nature (1996) 4.61
Transgenic mice that express a myelin basic protein-specific T cell receptor develop spontaneous autoimmunity. Cell (1993) 4.59
Restricted use of T cell receptor V genes in murine autoimmune encephalomyelitis raises possibilities for antibody therapy. Cell (1988) 4.47
Genes of the major histocompatibility complex of the mouse. Annu Rev Immunol (1983) 4.44
An immunoglobulin heavy-chain gene is formed by at least two recombinational events. Nature (1980) 3.99
IgG antibodies to phosphorylcholine exhibit more diversity than their IgM counterparts. Nature (1981) 3.86
Prostate-localized and androgen-regulated expression of the membrane-bound serine protease TMPRSS2. Cancer Res (1999) 3.79
Silkmoth chorion proteins: sequence analysis of the products of a multigene family. Proc Natl Acad Sci U S A (1978) 3.60
Structural studies of the scrapie prion protein using mass spectrometry and amino acid sequencing. Biochemistry (1993) 3.54
Introduced T cell receptor variable region gene segments recombine in pre-B cells: evidence that B and T cells use a common recombinase. Cell (1986) 3.51
Large-scale and automated DNA sequence determination. Science (1991) 3.45
Cell-type-specific cDNA probes and the murine I region: the localization and orientation of Ad alpha. Proc Natl Acad Sci U S A (1984) 3.43
The human T cell antigen receptor is encoded by variable, diversity, and joining gene segments that rearrange to generate a complete V gene. Cell (1984) 3.41
Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway. Immunity (1997) 3.33
T cell antigen receptors and the immunoglobulin supergene family. Cell (1985) 3.23
Cell-cell interaction in prostate gene regulation and cytodifferentiation. Proc Natl Acad Sci U S A (1997) 3.22
Immunoglobulin heavy chain gene organization in mice: analysis of a myeloma genomic clone containing variable and alpha constant regions. Proc Natl Acad Sci U S A (1979) 3.19
The structure, rearrangement and expression of D beta gene segments of the murine T-cell antigen receptor. Nature (1984) 3.18
DNA sequence of a gene encoding a BALB/c mouse Ld transplantation antigen. Science (1982) 3.17
Mechanism of antibody diversity: germ line basis for variability. Science (1970) 3.05
Predominant use of a V alpha gene segment in mouse T-cell receptors for cytochrome c. Nature (1987) 2.99
Understanding the adaptation of Halobacterium species NRC-1 to its extreme environment through computational analysis of its genome sequence. Genome Res (2001) 2.92
Complete genomic sequence and analysis of 117 kb of human DNA containing the gene BRCA1. Genome Res (1996) 2.91
Automated DNA diagnostics using an ELISA-based oligonucleotide ligation assay. Proc Natl Acad Sci U S A (1990) 2.88
Genes of the major histocompatibility complex in mouse and man. Science (1983) 2.88
Rearrangement of genetic information may produce immunoglobulin diversity. Nature (1979) 2.84
Mechanism of antibody synthesis: size differences between mouse kappa chains. Science (1967) 2.77
Zinc-dependent structure of a single-finger domain of yeast ADR1. Science (1988) 2.76
DNA sequence determination by hybridization: a strategy for efficient large-scale sequencing. Science (1993) 2.76
From hematopoiesis to neuropoiesis: evidence of overlapping genetic programs. Proc Natl Acad Sci U S A (2001) 2.66
Dynorphin-(1-13), an extraordinarily potent opioid peptide. Proc Natl Acad Sci U S A (1979) 2.66
The complete 685-kilobase DNA sequence of the human beta T cell receptor locus. Science (1996) 2.62
Mouse Cmu heavy chain immunoglobulin gene segment contains three intervening sequences separating domains. Nature (1980) 2.52
Separate elements control DJ and VDJ rearrangement in a transgenic recombination substrate. EMBO J (1990) 2.52
Identification of the class I genes of the mouse major histocompatibility complex by DNA-mediated gene transfer. Nature (1982) 2.48
Comparative hybridization of an array of 21,500 ovarian cDNAs for the discovery of genes overexpressed in ovarian carcinomas. Gene (1999) 2.45
Messenger RNA translation state: the second dimension of high-throughput expression screening. Proc Natl Acad Sci U S A (1999) 2.42
Mouse c-myc oncogene is located on chromosome 15 and translocated to chromosome 12 in plasmacytomas. Science (1982) 2.40
Genomic organization of the genes encoding mouse T-cell receptor alpha-chain. Nature (1985) 2.40
Cloning and characterization of two Toll/Interleukin-1 receptor-like genes TIL3 and TIL4: evidence for a multi-gene receptor family in humans. Blood (1998) 2.33
Direct evidence for chromosomal inversion during T-cell receptor beta-gene rearrangements. Nature (1986) 2.33
Rearrangement and transcription of the beta-chain genes of the T-cell antigen receptor in different types of murine lymphocytes. Nature (1985) 2.29
Expression of a myelin basic protein gene in transgenic shiverer mice: correction of the dysmyelinating phenotype. Cell (1987) 2.29
The joining of V and J gene segments creates antibody diversity. Nature (1980) 2.28
The human homolog of rat Jagged1 expressed by marrow stroma inhibits differentiation of 32D cells through interaction with Notch1. Immunity (1998) 2.23
Modulation of the NF-kappa B pathway by virally encoded death effector domains-containing proteins. Oncogene (1999) 2.21
Diversity and structure of human T-cell receptor beta-chain variable region genes. Proc Natl Acad Sci U S A (1986) 2.19
Rearranged beta T cell receptor genes in a helper T cell clone specific for lysozyme: no correlation between V beta and MHC restriction. Cell (1985) 2.14
Systems cancer medicine: towards realization of predictive, preventive, personalized and participatory (P4) medicine. J Intern Med (2012) 2.13
Gene transfer of H-2 class II genes: antigen presentation by mouse fibroblast and hamster B-cell lines. Cell (1984) 2.12
Nucleotide sequence of a light chain gene of the mouse I-A subregion: A beta d. Science (1983) 2.12
Evidence for a rare prostate cancer-susceptibility locus at chromosome 1p36. Am J Hum Genet (1999) 2.12
Modeling the feasibility of whole genome shotgun sequencing using a pairwise end strategy. Genomics (2000) 2.05
Chromosomal mapping of mouse myelin basic protein gene and structure and transcription of the partially deleted gene in shiverer mutant mice. Cell (1985) 2.02
Pulsed field gel electrophoresis. Biotechniques (1989) 2.02
Soluble protein of the organic matrix of mollusk shells: a potential template for shell formation. Science (1975) 1.99
Cloning and characterization of the myelin basic protein gene from mouse: one gene can encode both 14 kd and 18.5 kd MBPs by alternate use of exons. Cell (1985) 1.98
Asparagine-linked glycosylation of the scrapie and cellular prion proteins. Arch Biochem Biophys (1989) 1.96
Expression of a murine polyclonal T cell receptor marker correlates with the use of specific members of the V beta 8 gene segment subfamily. J Exp Med (1987) 1.96
Genetic mapping in the major histocompatibility complex by restriction enzyme site polymorphisms: most mouse class I genes map to the Tla complex. Proc Natl Acad Sci U S A (1983) 1.96
Immunoglobulin structure: amino terminal sequences of mouse myeloma proteins that bind phosphorylcholine. Science (1974) 1.94
Amino acid sequence of homogeneous antibodies to dextran and DNA rearrangements in heavy chain V-region gene segments. Nature (1980) 1.94
Linkage and sequence homology of two human immunoglobulin gamma heavy chain constant region genes. Proc Natl Acad Sci U S A (1982) 1.93
Identification of a diversity segment of human T-cell receptor beta-chain, and comparison with the analogous murine element. Nature (1984) 1.92
Comparative genomics of the human and mouse T cell receptor loci. Immunity (2001) 1.92
The immunoglobulin mu chains of membrane-bound and secreted IgM molecules differ in their C-terminal segments. Cell (1980) 1.91
Expression and function of transplantation antigens with altered or deleted cytoplasmic domains. Cell (1983) 1.86
Regulation of gene expression by interferons: control of H-2 promoter responses. Science (1988) 1.85
Sequence-tagged connectors: a sequence approach to mapping and scanning the human genome. Proc Natl Acad Sci U S A (1999) 1.85
Mouse immunoglobulin chains. A survey of the amino-terminal sequences of kappa chains. Biochemistry (1973) 1.85
Molecular cloning of translocations involving chromosome 15 and the immunoglobulin C alpha gene from chromosome 12 in two murine plasmacytomas. Proc Natl Acad Sci U S A (1982) 1.84
Retracted Amino acid variations at a single residue in an autoimmune peptide profoundly affect its properties: T-cell activation, major histocompatibility complex binding, and ability to block experimental allergic encephalomyelitis. Proc Natl Acad Sci U S A (1990) 1.82
Rearrangement and expression of T cell antigen receptor and gamma genes during thymic development. J Exp Med (1986) 1.82
Diversity of the immunoglobulin gene superfamily. Adv Immunol (1989) 1.81
Snapshot of a large dynamic replicon in a halophilic archaeon: megaplasmid or minichromosome? Genome Res (1998) 1.81
Activation of the NF-kappaB pathway by caspase 8 and its homologs. Oncogene (2000) 1.76
Delays to thrombolysis in the treatment of myocardial infarction. J R Coll Physicians Lond (1993) 1.75
Mouse immunoglobulin chains. Pattern of sequence variation among kappa chains with limited sequence differences. Biochemistry (1973) 1.75