Published in RNA on February 09, 2005
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MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies. Nat Cell Biol (2005) 12.12
A crucial role for GW182 and the DCP1:DCP2 decapping complex in miRNA-mediated gene silencing. RNA (2005) 5.15
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Expanding the microRNA targeting code: functional sites with centered pairing. Mol Cell (2010) 4.20
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The 3'-to-5' exoribonuclease Nibbler shapes the 3' ends of microRNAs bound to Drosophila Argonaute1. Curr Biol (2011) 1.66
A Tetrahymena Piwi bound to mature tRNA 3' fragments activates the exonuclease Xrn2 for RNA processing in the nucleus. Mol Cell (2012) 1.65
Uridylation of mature miRNAs and siRNAs by the MUT68 nucleotidyltransferase promotes their degradation in Chlamydomonas. Proc Natl Acad Sci U S A (2010) 1.58
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Arabidopsis thaliana XRN2 is required for primary cleavage in the pre-ribosomal RNA. Nucleic Acids Res (2010) 1.07
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Scavenger decapping activity facilitates 5' to 3' mRNA decay. Mol Cell Biol (2005) 1.05
RNA-mediated silencing in Algae: biological roles and tools for analysis of gene function. Eukaryot Cell (2011) 1.02
Degradation of a polyadenylated rRNA maturation by-product involves one of the three RRP6-like proteins in Arabidopsis thaliana. Mol Cell Biol (2008) 1.02
Dimeric heat shock protein 40 binds radial spokes for generating coupled power strokes and recovery strokes of 9 + 2 flagella. J Cell Biol (2008) 1.01
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Posttranscriptional regulation of gene expression by Piwi proteins and piRNAs. Mol Cell (2014) 0.96
Both treated and untreated tumors are eliminated by short hairpin RNA-based induction of target-specific immune responses. Proc Natl Acad Sci U S A (2009) 0.95
The role of RNA interference (RNAi) in arbovirus-vector interactions. Viruses (2015) 0.93
A genome-wide RNAi screen identifies genes regulating the formation of P bodies in C. elegans and their functions in NMD and RNAi. Protein Cell (2011) 0.93
Multiple myeloma-associated hDIS3 mutations cause perturbations in cellular RNA metabolism and suggest hDIS3 PIN domain as a potential drug target. Nucleic Acids Res (2013) 0.93
Distinct sets of PIWI proteins produce arbovirus and transposon-derived piRNAs in Aedes aegypti mosquito cells. Nucleic Acids Res (2015) 0.92
MicroRNAs: Emerging Novel Clinical Biomarkers for Hepatocellular Carcinomas. J Clin Med (2015) 0.91
Detection of siRNA induced mRNA silencing by RT-qPCR: considerations for experimental design. BMC Res Notes (2010) 0.91
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Methylation protects microRNAs from an AGO1-associated activity that uridylates 5' RNA fragments generated by AGO1 cleavage. Proc Natl Acad Sci U S A (2014) 0.89
XRN1 stalling in the 5' UTR of Hepatitis C virus and Bovine Viral Diarrhea virus is associated with dysregulated host mRNA stability. PLoS Pathog (2015) 0.88
Context-dependent dual role of SKI8 homologs in mRNA synthesis and turnover. PLoS Genet (2012) 0.87
OLFML3 expression is decreased during prenatal muscle development and regulated by microRNA-155 in pigs. Int J Biol Sci (2012) 0.85
RNA decay and RNA silencing in plants: competition or collaboration? Front Plant Sci (2011) 0.85
The C-terminal extension of Lsm4 interacts directly with the 3' end of the histone mRNP and is required for efficient histone mRNA degradation. RNA (2013) 0.85
PLANT HOMOLOGOUS TO PARAFIBROMIN is a component of the PAF1 complex and assists in regulating expression of genes within H3K27ME3-enriched chromatin. Plant Physiol (2010) 0.85
Global organization of protein complexome in the yeast Saccharomyces cerevisiae. BMC Syst Biol (2011) 0.84
The role of miRNAs in stress-responsive hepatic stellate cells during liver fibrosis. Front Physiol (2015) 0.84
Crystal structure of the S. solfataricus archaeal exosome reveals conformational flexibility in the RNA-binding ring. PLoS One (2010) 0.83
Small-interfering RNAs (siRNAs) as a promising tool for ocular therapy. Br J Pharmacol (2013) 0.83
Asian Citrus Psyllid Expression Profiles Suggest Candidatus Liberibacter Asiaticus-Mediated Alteration of Adult Nutrition and Metabolism, and of Nymphal Development and Immunity. PLoS One (2015) 0.83
A view to a kill: structure of the RNA exosome. Cell (2006) 0.83
Proteins involved in the degradation of cytoplasmic mRNA in the major eukaryotic model systems. RNA Biol (2014) 0.83
The 5'-3' exoribonuclease Pacman (Xrn1) regulates expression of the heat shock protein Hsp67Bc and the microRNA miR-277-3p in Drosophila wing imaginal discs. RNA Biol (2013) 0.82
Argonaute proteins affect siRNA levels and accumulation of a novel extrachromosomal DNA from the Dictyostelium retrotransposon DIRS-1. J Biol Chem (2014) 0.81
Xrn1/Pacman affects apoptosis and regulates expression of hid and reaper. Biol Open (2015) 0.81
Crystal structure of an archaeal Ski2p-like protein from Pyrococcus horikoshii OT3. Protein Sci (2007) 0.80
Diverse aberrancies target yeast mRNAs to cytoplasmic mRNA surveillance pathways. Biochim Biophys Acta (2008) 0.80
Small RNAs meet their targets: when methylation defends miRNAs from uridylation. RNA Biol (2014) 0.80
RNA cleavage products generated by antisense oligonucleotides and siRNAs are processed by the RNA surveillance machinery. Nucleic Acids Res (2016) 0.80
RNAi-mediated gene silencing in tick synganglia: a proof of concept study. BMC Biotechnol (2008) 0.79
TNF-alpha stimulation inhibits siRNA-mediated RNA interference through a mechanism involving poly-(A) tail stabilization. Biochim Biophys Acta (2008) 0.78
RNA Quality Control as a Key to Suppressing RNA Silencing of Endogenous Genes in Plants. Mol Plant (2016) 0.78
RNA-seq reveals post-transcriptional regulation of Drosophila insulin-like peptide dilp8 and the neuropeptide-like precursor Nplp2 by the exoribonuclease Pacman/XRN1. Nucleic Acids Res (2015) 0.78
siRNA induces gelsolin gene transcription activation in human esophageal cancer cell. Sci Rep (2015) 0.78
Oligoadenylation of 3' decay intermediates promotes cytoplasmic mRNA degradation in Drosophila cells. RNA (2016) 0.77
Gene targeting in primary human trophoblasts. Placenta (2012) 0.77
SKI2 mediates degradation of RISC 5'-cleavage fragments and prevents secondary siRNA production from miRNA targets in Arabidopsis. Nucleic Acids Res (2015) 0.76
Exome sequencing identifies a novel TTC37 mutation in the first reported case of Trichohepatoenteric syndrome (THE-S) in South Africa. BMC Med Genet (2017) 0.75
Attacked from All Sides: RNA Decay in Antiviral Defense. Viruses (2017) 0.75
Genome-wide exonic small interference RNA-mediated gene silencing regulates sexual reproduction in the homothallic fungus Fusarium graminearum. PLoS Genet (2017) 0.75
SUPERKILLER Complex Components Are Required for the RNA Exosome-Mediated Control of Cuticular Wax Biosynthesis in Arabidopsis Inflorescence Stems. Plant Physiol (2016) 0.75
Fluorinated Nucleotide Modifications Modulate Allele Selectivity of SNP-Targeting Antisense Oligonucleotides. Mol Ther Nucleic Acids (2017) 0.75
RNA Exosome and Non-coding RNA-Coupled Mechanisms in AID-Mediated Genomic Alterations. J Mol Biol (2017) 0.75
Microporation is an efficient method for siRNA-induced knockdown of PEX5 in HepG2 cells: evaluation of the transfection efficiency, the PEX5 mRNA and protein levels and induction of peroxisomal deficiency. Histochem Cell Biol (2014) 0.75
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A divergent Sm fold in EDC3 proteins mediates DCP1 binding and P-body targeting. Mol Cell Biol (2007) 1.23
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Nuclear export of mRNA by TAP/NXF1 requires two nucleoporin-binding sites but not p15. Mol Cell Biol (2002) 1.18
GW182 proteins cause PABP dissociation from silenced miRNA targets in the absence of deadenylation. EMBO J (2013) 1.17
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DCP1 forms asymmetric trimers to assemble into active mRNA decapping complexes in metazoa. Proc Natl Acad Sci U S A (2009) 1.08
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The SMG5-SMG7 heterodimer directly recruits the CCR4-NOT deadenylase complex to mRNAs containing nonsense codons via interaction with POP2. Genes Dev (2013) 1.07
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The C-terminal alpha-alpha superhelix of Pat is required for mRNA decapping in metazoa. EMBO J (2010) 1.00
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miRISC recruits decapping factors to miRNA targets to enhance their degradation. Nucleic Acids Res (2013) 0.93
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