Published in J Mol Biol on July 25, 2003
Crystal structure of domain-swapped STE20 OSR1 kinase domain. Protein Sci (2009) 1.87
PoPMuSiC 2.1: a web server for the estimation of protein stability changes upon mutation and sequence optimality. BMC Bioinformatics (2011) 1.76
Structure and interactions of the C-terminal metal binding domain of Archaeoglobus fulgidus CopA. Proteins (2010) 0.86
Influence of point mutations on the stability, dimerization, and oligomerization of human cystatin C and its L68Q variant. Front Mol Neurosci (2012) 0.84
Functional repertoire, molecular pathways and diseases associated with 3D domain swapping in the human proteome. J Clin Bioinforma (2012) 0.82
Effective harmonic potentials: insights into the internal cooperativity and sequence-specificity of protein dynamics. PLoS Comput Biol (2013) 0.81
Detection and alignment of 3D domain swapping proteins using angle-distance image-based secondary structural matching techniques. PLoS One (2010) 0.81
Cooperative fluctuations point to the dimerization interface of p53 core domain. Biophys J (2006) 0.80
Domain-swapped dimer of Pseudomonas aeruginosa cytochrome c551: structural insights into domain swapping of cytochrome c family proteins. PLoS One (2015) 0.80
Structure of a mutant β toxin from Staphylococcus aureus reveals domain swapping and conformational flexibility. Acta Crystallogr Sect F Struct Biol Cryst Commun (2011) 0.75
Crystal structures of the Arabidopsis thaliana organellar RNA editing factors MORF1 and MORF9. Nucleic Acids Res (2017) 0.75
Unfolding the HIV-1 reverse transcriptase RNase H domain - how to lose a molecular tug-of-war. Nucleic Acids Res (2016) 0.75
Structural characterization of V57D and V57P mutants of human cystatin C, an amyloidogenic protein. Acta Crystallogr D Biol Crystallogr (2013) 0.75
Amino-acid composition after loop deletion drives domain swapping. Protein Sci (2017) 0.75
Fast and accurate predictions of protein stability changes upon mutations using statistical potentials and neural networks: PoPMuSiC-2.0. Bioinformatics (2009) 2.03
PoPMuSiC 2.1: a web server for the estimation of protein stability changes upon mutation and sequence optimality. BMC Bioinformatics (2011) 1.76
BeAtMuSiC: Prediction of changes in protein-protein binding affinity on mutations. Nucleic Acids Res (2013) 1.21
Community-wide evaluation of methods for predicting the effect of mutations on protein-protein interactions. Proteins (2013) 1.20
Enhancing the stability and solubility of TEV protease using in silico design. Protein Sci (2007) 1.17
Specificity and phenetic relationships of iron- and manganese-containing superoxide dismutases on the basis of structure and sequence comparisons. J Biol Chem (2003) 1.09
Assessment of Plasmodium falciparum resistance to ferroquine (SSR97193) in field isolates and in W2 strain under pressure. Malar J (2006) 1.06
Antimalarial versus cytotoxic properties of dual drugs derived from 4-aminoquinolines and Mannich bases: interaction with DNA. J Med Chem (2010) 1.03
The antimalarial ferroquine: role of the metal and intramolecular hydrogen bond in activity and resistance. ACS Chem Biol (2011) 0.99
Evidence that interaction between conserved residues in transmembrane helices 2, 3, and 7 are crucial for human VPAC1 receptor activation. Mol Pharmacol (2010) 0.99
Ferroquine, an ingenious antimalarial drug: thoughts on the mechanism of action. Molecules (2008) 0.98
The first peptides: the evolutionary transition between prebiotic amino acids and early proteins. J Theor Biol (2009) 0.98
Ferrocene conjugates of chloroquine and other antimalarials: the development of ferroquine, a new antimalarial. ChemMedChem (2008) 0.97
A conserved cysteine residue is involved in disulfide bond formation between plant plasma membrane aquaporin monomers. Biochem J (2012) 0.96
Probing the energetic and structural role of amino acid/nucleobase cation-pi interactions in protein-ligand complexes. J Biol Chem (2002) 0.94
Flanking domain stability modulates the aggregation kinetics of a polyglutamine disease protein. Protein Sci (2011) 0.93
Plasmodium falciparum apicoplast drugs: targets or off-targets? Chem Rev (2011) 0.92
In vitro metabolism of ferroquine (SSR97193) in animal and human hepatic models and antimalarial activity of major metabolites on Plasmodium falciparum. Drug Metab Dispos (2006) 0.91
Structure-based mutant stability predictions on proteins of unknown structure. J Biotechnol (2012) 0.90
Stair motifs at protein-DNA interfaces: nonadditivity of H-bond, stacking, and cation-pi interactions. J Am Chem Soc (2004) 0.89
Thermostability of salt bridges versus hydrophobic interactions in proteins probed by statistical potentials. J Chem Inf Model (2007) 0.88
Development of novel statistical potentials describing cation-pi interactions in proteins and comparison with semiempirical and quantum chemistry approaches. J Chem Inf Model (2006) 0.88
Enhancement of the antimalarial activity of ciprofloxacin using a double prodrug/bioorganometallic approach. J Med Chem (2009) 0.87
Synthesis of ferroquine enantiomers: first investigation of effects of metallocenic chirality upon antimalarial activity and cytotoxicity. Chembiochem (2002) 0.87
Structural analysis of an unusual bioactive N-acylated lipo-oligosaccharide LOS-IV in Mycobacterium marinum. J Am Chem Soc (2010) 0.87
In vitro and in silico design of alpha1-antitrypsin mutants with different conformational stabilities. J Mol Biol (2003) 0.86
Free-energy calculations of protein-ligand cation-pi and amino-pi interactions: from vacuum to proteinlike environments. J Am Chem Soc (2003) 0.86
SODa: an Mn/Fe superoxide dismutase prediction and design server. BMC Bioinformatics (2008) 0.86
The apicoplast: a key target to cure malaria. Curr Pharm Des (2012) 0.85
Thermo- and mesostabilizing protein interactions identified by temperature-dependent statistical potentials. Biophys J (2010) 0.85
Modeling the temporal evolution of the Drosophila gene expression from DNA microarray time series. Phys Biol (2009) 0.84
Cation-π, amino-π, π-π, and H-bond interactions stabilize antigen-antibody interfaces. Proteins (2014) 0.84
Database-derived potentials dependent on protein size for in silico folding and design. Biophys J (2004) 0.84
The antimalarial ferroquine is an inhibitor of hepatitis C virus. Hepatology (2013) 0.84
Revisiting the correlation between proteins' thermoresistance and organisms' thermophilicity. Protein Eng Des Sel (2008) 0.84
Investigation of the redox behavior of ferroquine, a new antimalarial. Mol Pharm (2008) 0.84
Mn/Fe superoxide dismutase interaction fingerprints and prediction of oligomerization and metal cofactor from sequence. Proteins (2008) 0.84
Pharmacokinetics of ferroquine, a novel 4-aminoquinoline, in asymptomatic carriers of Plasmodium falciparum infections. Antimicrob Agents Chemother (2012) 0.83
Robust non-linear differential equation models of gene expression evolution across Drosophila development. BMC Res Notes (2012) 0.83
Antimalarial activities of ferroquine conjugates with either glutathione reductase inhibitors or glutathione depletors via a hydrolyzable amide linker. Bioorg Med Chem (2009) 0.81
Medicinal potential of ciprofloxacin and its derivatives. Future Med Chem (2013) 0.81
Dynamic modeling of gene expression in prokaryotes: application to glucose-lactose diauxie in Escherichia coli. Syst Synth Biol (2011) 0.80
Gene expression model (in)validation by Fourier analysis. BMC Syst Biol (2010) 0.80
Platinum(II) and palladium(II) complexes with (N,N') and (C,N,N')- ligands derived from pyrazole as anticancer and antimalarial agents: synthesis, characterization and in vitro activities. J Inorg Biochem (2011) 0.80
Synthesis and in vitro antitubercular activity of ferrocene-based hydrazones. Bioorg Med Chem Lett (2011) 0.80
In situ nanochemical imaging of label-free drugs: a case study of antimalarials in Plasmodium falciparum-infected erythrocytes. Chem Commun (Camb) (2011) 0.79
Design principles of a genetic alarm clock. PLoS One (2012) 0.79
Synthesis and antimalarial activities of rhenium bioorganometallics based on the 4-aminoquinoline structure. Bioorg Med Chem (2010) 0.79
7-chloroquinoline-isatin conjugates: antimalarial, antitubercular, and cytotoxic evaluation. Chem Biol Drug Des (2014) 0.78
The ferroquine antimalarial conundrum: redox activation and reinvasion inhibition. Angew Chem Int Ed Engl (2013) 0.78
Modelling and bioinformatics analysis of the dimeric structure of house dust mite allergens from families 5 and 21: Der f 5 could dimerize as Der p 5. J Biomol Struct Dyn (2012) 0.78
Alkynyl monosaccharide analogues as a tool for evaluating Golgi glycosylation efficiency: application to Congenital Disorders of Glycosylation (CDG). Chem Commun (Camb) (2013) 0.78
In vitro and in vivo antischistosomal activity of ferroquine derivatives. Parasit Vectors (2014) 0.77
Mapping the expressed glycome and glycosyltransferases of zebrafish liver cells as a relevant model system for glycosylation studies. J Proteome Res (2012) 0.77
Azide-alkyne cycloaddition en route towards 1H-1,2,3-triazole-tethered β-lactam-ferrocene and β-lactam-ferrocenylchalcone conjugates: synthesis and in vitro anti-tubercular evaluation. Dalton Trans (2012) 0.76
Novel ferrocenic steroidal drug derivatives and their bioactivities. J Med Chem (2010) 0.76
α-L-fucosidase inhibition by pyrrolidine-ferrocene hybrids: rationalization of ligand-binding properties by structural studies. Chemistry (2013) 0.75
Synthesis and in vitro anti-tubercular evaluation of 1,2,3-triazole tethered β-lactam-ferrocene and β-lactam-ferrocenylchalcone chimeric scaffolds. Dalton Trans (2012) 0.75
4-Aminoquinoline-β-lactam conjugates: synthesis, antimalarial, and antitubercular evaluation. Chem Biol Drug Des (2013) 0.75
Assessing ER and Golgi N-glycosylation process using metabolic labeling in mammalian cultured cells. Methods Cell Biol (2013) 0.75
What is paradoxical about Levinthal paradox? J Biomol Struct Dyn (2002) 0.75
Iminosugar-ferrocene conjugates as potential anticancer agents. Org Biomol Chem (2012) 0.75
Solvent-induced effects: self-association of positively charged pi systems. J Am Chem Soc (2006) 0.75
Statistical methodology for the detection of small changes in distances by EXAFS: application to the antimalarial ruthenoquine. J Phys Chem A (2012) 0.75
Prelude and Fugue, predicting local protein structure, early folding regions and structural weaknesses. Bioinformatics (2006) 0.75
Ferrocene-based antimalarials. Future Med Chem (2012) 0.75
[From cannabis to selective CB2R agonists: molecules with numerous therapeutical virtues]. Med Sci (Paris) (2013) 0.75