Published in J Cell Sci on May 01, 2006
Plasticity of cell migration: a multiscale tuning model. J Cell Biol (2009) 5.82
Dynamic reciprocity in the wound microenvironment. Wound Repair Regen (2011) 1.62
Thrombospondin 1 is a key mediator of transforming growth factor β-mediated cell contractility in systemic sclerosis via a mitogen-activated protein kinase kinase (MEK)/extracellular signal-regulated kinase (ERK)-dependent mechanism. Fibrogenesis Tissue Repair (2011) 1.48
Fibrosis in connective tissue disease: the role of the myofibroblast and fibroblast-epithelial cell interactions. Arthritis Res Ther (2007) 1.47
Hypertrophic scar formation following burns and trauma: new approaches to treatment. PLoS Med (2007) 1.42
Integrins α2β1 and α11β1 regulate the survival of mesenchymal stem cells on collagen I. Cell Death Dis (2011) 1.19
The fibroblast integrin alpha11beta1 is induced in a mechanosensitive manner involving activin A and regulates myofibroblast differentiation. J Biol Chem (2010) 1.15
FAK activation and the role of epithelial membrane protein 2 (EMP2) in collagen gel contraction. Invest Ophthalmol Vis Sci (2008) 1.06
A role for decorin in controlling proliferation, adhesion, and migration of murine embryonic fibroblasts. J Biomed Mater Res A (2010) 1.06
Endorepellin, the C-terminal angiostatic module of perlecan, enhances collagen-platelet responses via the alpha2beta1-integrin receptor. Blood (2006) 1.02
Alpha11 beta1 integrin-dependent regulation of periodontal ligament function in the erupting mouse incisor. Mol Cell Biol (2007) 1.02
Identification and characterization of an anti-fibrotic benzopyran compound isolated from mangrove-derived Streptomyces xiamenensis. Mar Drugs (2012) 0.96
Proteomic profiling of endorepellin angiostatic activity on human endothelial cells. Proteome Sci (2008) 0.87
Collagen XXIII, novel ligand for integrin alpha2beta1 in the epidermis. J Biol Chem (2011) 0.83
Regulation of the atheroma-enriched protein, SPRR3, in vascular smooth muscle cells through cyclic strain is dependent on integrin alpha1beta1/collagen interaction. Am J Pathol (2008) 0.82
Reduced granulation tissue and wound strength in the absence of α11β1 integrin. J Invest Dermatol (2015) 0.81
Induction of initial steps of angiogenic differentiation and maturation of endothelial cells by pericytes in vitro and the role of collagen IV. Histochem Cell Biol (2016) 0.81
Dwarfism in mice lacking collagen-binding integrins α2β1 and α11β1 is caused by severely diminished IGF-1 levels. J Biol Chem (2011) 0.81
Loss of the α2β1 integrin alters human papilloma virus-induced squamous carcinoma progression in vivo and in vitro. PLoS One (2011) 0.80
Clavanin A improves outcome of complications from different bacterial infections. Antimicrob Agents Chemother (2014) 0.79
The extracellular matrix microtopography drives critical changes in cellular motility and Rho A activity in colon cancer cells. Cancer Cell Int (2010) 0.78
Rewiring integrin-mediated signaling and cellular response with the peripheral myelin protein 22 and epithelial membrane protein 2 components of the tetraspan web. Invest Ophthalmol Vis Sci (2011) 0.76
Suppressive effects of induced pluripotent stem cell-conditioned medium on in vitro hypertrophic scarring fibroblast activation. Mol Med Rep (2014) 0.75
Scleroderma. N Engl J Med (2009) 6.50
Inflammation in wound repair: molecular and cellular mechanisms. J Invest Dermatol (2007) 5.16
Integrins. Cell Tissue Res (2009) 4.11
Differential roles of macrophages in diverse phases of skin repair. J Immunol (2010) 3.56
Keratinocyte-fibroblast interactions in wound healing. J Invest Dermatol (2007) 3.51
TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2. Nature (2002) 3.21
Cardioprotection by S-nitrosation of a cysteine switch on mitochondrial complex I. Nat Med (2013) 3.10
Multiple, brief coronary occlusions during early reperfusion protect rabbit hearts by targeting cell signaling pathways. J Am Coll Cardiol (2004) 2.94
E-cadherin is essential for in vivo epidermal barrier function by regulating tight junctions. EMBO J (2005) 2.72
Cardiac troponin I but not cardiac troponin T induces severe autoimmune inflammation in the myocardium. Circulation (2006) 2.58
T cell-specific inactivation of the interleukin 10 gene in mice results in enhanced T cell responses but normal innate responses to lipopolysaccharide or skin irritation. J Exp Med (2004) 2.58
CCR2 recruits an inflammatory macrophage subpopulation critical for angiogenesis in tissue repair. Blood (2012) 2.43
Mast cells are key promoters of contact allergy that mediate the adjuvant effects of haptens. Immunity (2011) 2.39
Integrin alpha 2-deficient mice develop normally, are fertile, but display partially defective platelet interaction with collagen. J Biol Chem (2002) 1.66
Pathogenic role for skin macrophages in a mouse model of keratinocyte-induced psoriasis-like skin inflammation. J Clin Invest (2006) 1.65
Bradykinin induces mitochondrial ROS generation via NO, cGMP, PKG, and mitoKATP channel opening and leads to cardioprotection. Am J Physiol Heart Circ Physiol (2003) 1.63
Integrin-linked kinase is required for epidermal and hair follicle morphogenesis. J Cell Biol (2007) 1.63
New developments in fibroblast and myofibroblast biology: implications for fibrosis and scleroderma. Curr Rheumatol Rep (2007) 1.54
Integrin alpha2beta1 is required for regulation of murine wound angiogenesis but is dispensable for reepithelialization. J Invest Dermatol (2006) 1.54
Kindlin-1 is a phosphoprotein involved in regulation of polarity, proliferation, and motility of epidermal keratinocytes. J Biol Chem (2006) 1.52
Interleukin-10 derived from macrophages and/or neutrophils regulates the inflammatory response to LPS but not the response to CpG DNA. Eur J Immunol (2006) 1.51
Keratin 14 Cre transgenic mice authenticate keratin 14 as an oocyte-expressed protein. Genesis (2004) 1.48
Developmental changes in contractility and sarcomeric proteins from the early embryonic to the adult stage in the mouse heart. J Physiol (2003) 1.47
Merkel cell polyomavirus DNA in persons without merkel cell carcinoma. Emerg Infect Dis (2009) 1.45
In vitro modeling of ryanodine receptor 2 dysfunction using human induced pluripotent stem cells. Cell Physiol Biochem (2011) 1.43
Enhanced expression levels of IL-31 correlate with IL-4 and IL-13 in atopic and allergic contact dermatitis. J Allergy Clin Immunol (2006) 1.43
[Patients' view of melanoma follow-up]. J Dtsch Dermatol Ges (2004) 1.43
Interrelation of immunity and tissue repair or regeneration. Semin Cell Dev Biol (2009) 1.42
A2b adenosine receptors in cardioprotection: timing is everything. J Mol Cell Cardiol (2010) 1.41
Myofibroblast differentiation is induced in keratinocyte-fibroblast co-cultures and is antagonistically regulated by endogenous transforming growth factor-beta and interleukin-1. Am J Pathol (2004) 1.39
Impaired epidermal wound healing in vivo upon inhibition or deletion of Rac1. J Cell Sci (2007) 1.39
Mast cell-specific Cre/loxP-mediated recombination in vivo. Transgenic Res (2007) 1.36
Keloids--clinical diagnosis, pathogenesis, and treatment options. J Dtsch Dermatol Ges (2004) 1.34
Multiple integrin-ligand interactions synergize in shear-resistant platelet adhesion at sites of arterial injury in vivo. Blood (2003) 1.32
Tumor suppressor function of laminin-binding alpha-dystroglycan requires a distinct beta3-N-acetylglucosaminyltransferase. Proc Natl Acad Sci U S A (2009) 1.32
Regulation of smooth muscle contraction by small GTPases. Physiology (Bethesda) (2009) 1.32
Integrin alpha 11 regulates IGF2 expression in fibroblasts to enhance tumorigenicity of human non-small-cell lung cancer cells. Proc Natl Acad Sci U S A (2007) 1.29
NECA and bradykinin at reperfusion reduce infarction in rabbit hearts by signaling through PI3K, ERK, and NO. J Mol Cell Cardiol (2004) 1.29
Mechanical tension and integrin alpha 2 beta 1 regulate fibroblast functions. J Investig Dermatol Symp Proc (2006) 1.26
Distinct in vivo expression patterns of survivin splice variants in renal cell carcinomas. Int J Cancer (2002) 1.23
Skin lesion development in a mouse model of incontinentia pigmenti is triggered by NEMO deficiency in epidermal keratinocytes and requires TNF signaling. Hum Mol Genet (2006) 1.22
Half-sarcomere dynamics in myofibrils during activation and relaxation studied by tracking fluorescent markers. Biophys J (2005) 1.22
Wound-healing defect of CD18(-/-) mice due to a decrease in TGF-beta1 and myofibroblast differentiation. EMBO J (2005) 1.22
Expression of integrin beta1 by fibroblasts is required for tissue repair in vivo. J Cell Sci (2010) 1.21
Cellular cardiomyoplasty improves survival after myocardial injury. Circulation (2002) 1.21
Protection through postconditioning or a mitochondria-targeted S-nitrosothiol is unaffected by cardiomyocyte-selective ablation of protein kinase G. Basic Res Cardiol (2013) 1.21
Keratinocytes from patients lacking collagen XVII display a migratory phenotype. Am J Pathol (2004) 1.20
Activities of the matrix metalloproteinase stromelysin-2 (MMP-10) in matrix degradation and keratinocyte organization in wounded skin. Mol Biol Cell (2004) 1.18
Home telemonitoring in patients with chronic heart failure: a chance to improve patient care? Dtsch Arztebl Int (2010) 1.17
XIAP expression is an independent prognostic marker in clear-cell renal carcinomas. Hum Pathol (2004) 1.16
The fibroblast integrin alpha11beta1 is induced in a mechanosensitive manner involving activin A and regulates myofibroblast differentiation. J Biol Chem (2010) 1.15
Dissecting the roles of endothelin, TGF-beta and GM-CSF on myofibroblast differentiation by keratinocytes. Thromb Haemost (2004) 1.15
Heterozygous deficiency of manganese superoxide dismutase results in severe lipid peroxidation and spontaneous apoptosis in murine myocardium in vivo. Free Radic Biol Med (2005) 1.14
Phosphodiesterase type 5 inhibition is a novel therapeutic option in Raynaud disease. Arch Intern Med (2006) 1.14
Silicone granuloma of the face treated with minocycline. J Am Acad Dermatol (2005) 1.12
Cell-matrix interactions in dermal repair and scarring. Fibrogenesis Tissue Repair (2010) 1.11
Gray platelet syndrome and defective thrombo-inflammation in Nbeal2-deficient mice. J Clin Invest (2013) 1.11
Differential proteomic analysis distinguishes tissue repair biomarker signatures in wound exudates obtained from normal healing and chronic wounds. J Proteome Res (2010) 1.10
Toll-like receptor-4 deficiency attenuates doxorubicin-induced cardiomyopathy in mice. Eur J Heart Fail (2008) 1.10
Accelerated wound closure in mice deficient for interleukin-10. Am J Pathol (2007) 1.09
Kindlin-1 Is required for RhoGTPase-mediated lamellipodia formation in keratinocytes. Am J Pathol (2009) 1.09
Plasmin modulates vascular endothelial growth factor-A-mediated angiogenesis during wound repair. Am J Pathol (2006) 1.09
Frequency of disease-associated and other nuclear autoantibodies in patients of the German Network for Systemic Scleroderma: correlation with characteristic clinical features. Arthritis Res Ther (2011) 1.09
Signalling and regulation of collagen I synthesis by ET-1 and TGF-beta1. FEBS J (2005) 1.08
Integrins during evolution: evolutionary trees and model organisms. Biochim Biophys Acta (2009) 1.08
Isometric force kinetics upon rapid activation and relaxation of mouse, guinea pig and human heart muscle studied on the subcellular myofibrillar level. Basic Res Cardiol (2002) 1.08
Thromboxane A2-induced bi-directional regulation of cerebral arterial tone. J Biol Chem (2008) 1.08
NECA at reperfusion limits infarction and inhibits formation of the mitochondrial permeability transition pore by activating p70S6 kinase. Basic Res Cardiol (2006) 1.07
Regulation of B cell homeostasis and activation by the tumor suppressor gene CYLD. J Exp Med (2007) 1.07
alpha-melanocyte-stimulating hormone suppresses bleomycin-induced collagen synthesis and reduces tissue fibrosis in a mouse model of scleroderma: melanocortin peptides as a novel treatment strategy for scleroderma? Arthritis Rheum (2009) 1.06
High frequency of corticosteroid and immunosuppressive therapy in patients with systemic sclerosis despite limited evidence for efficacy. Arthritis Res Ther (2009) 1.05
Identification of cardiac troponin I sequence motifs leading to heart failure by induction of myocardial inflammation and fibrosis. Circulation (2008) 1.05
Mapping preconditioning's signaling pathways: an engineering approach. Ann N Y Acad Sci (2008) 1.05
alpha 11beta 1 integrin recognizes the GFOGER sequence in interstitial collagens. J Biol Chem (2002) 1.04
Cardioprotective effects of mineralocorticoid receptor antagonists at reperfusion. Eur Heart J (2009) 1.03
Integrin alpha2beta1 is the required receptor for endorepellin angiostatic activity. J Biol Chem (2007) 1.03
The mitochondrial electron transport chain is dispensable for proliferation and differentiation of epidermal progenitor cells. Stem Cells (2011) 1.03
CD4+ T cell-associated pathophysiology critically depends on CD18 gene dose effects in a murine model of psoriasis. J Immunol (2003) 1.03
Stabilization of integrin-linked kinase by the Hsp90-CHIP axis impacts cellular force generation, migration and the fibrotic response. EMBO J (2013) 1.02
Molecular mechanisms of VEGF-A action during tissue repair. J Investig Dermatol Symp Proc (2006) 1.02
α11 integrin stimulates myofibroblast differentiation in diabetic cardiomyopathy. Cardiovasc Res (2012) 1.02
[AWMF Guideline no. 013/066. Diagnosis and therapy of circumscribed scleroderma]. J Dtsch Dermatol Ges (2009) 1.02
Alpha11 beta1 integrin-dependent regulation of periodontal ligament function in the erupting mouse incisor. Mol Cell Biol (2007) 1.02
Binding of laminin alpha1-chain LG4-5 domain to alpha-dystroglycan causes tyrosine phosphorylation of syntrophin to initiate Rac1 signaling. Biochemistry (2006) 1.01
Role of tyrosine phosphatase SHP-1 in the mechanism of endorepellin angiostatic activity. Blood (2009) 1.01
Both A2a and A2b adenosine receptors at reperfusion are necessary to reduce infarct size in mouse hearts. Am J Physiol Heart Circ Physiol (2010) 1.00
A fast protocol for infarct quantification in mice. J Magn Reson Imaging (2013) 1.00
The endothelin receptor blocker bosentan inhibits doxorubicin-induced cardiomyopathy. Cancer Res (2007) 1.00