Published in Oncogene on August 22, 2011
MicroRNAs in cancer. Annu Rev Pathol (2013) 3.50
Genome-scale analysis of DNA methylation in lung adenocarcinoma and integration with mRNA expression. Genome Res (2012) 2.10
Concern The functional role of long non-coding RNAs and epigenetics. Biol Proced Online (2014) 1.73
Global Decrease of Histone H3K27 Acetylation in ZEB1-Induced Epithelial to Mesenchymal Transition in Lung Cancer Cells. Cancers (Basel) (2013) 1.65
MicroRNAome genome: a treasure for cancer diagnosis and therapy. CA Cancer J Clin (2014) 1.40
miR-30d, miR-181a and miR-199a-5p cooperatively suppress the endoplasmic reticulum chaperone and signaling regulator GRP78 in cancer. Oncogene (2012) 1.34
Genome-wide DNA methylation changes with age in disease-free human skeletal muscle. Aging Cell (2013) 1.08
Modulation of neuroblastoma disease pathogenesis by an extensive network of epigenetically regulated microRNAs. Oncogene (2012) 1.05
Epigenetic deregulation of miR-29a and miR-1256 by isoflavone contributes to the inhibition of prostate cancer cell growth and invasion. Epigenetics (2012) 1.00
Hepatitis B virus X protein inhibits tumor suppressor miR-205 through inducing hypermethylation of miR-205 promoter to enhance carcinogenesis. Neoplasia (2013) 1.00
Epigenetic silencing of microRNA-199b-5p is associated with acquired chemoresistance via activation of JAG1-Notch1 signaling in ovarian cancer. Oncotarget (2014) 0.99
An updated review of gastric cancer in the next-generation sequencing era: insights from bench to bedside and vice versa. World J Gastroenterol (2014) 0.98
Human papilloma virus, DNA methylation and microRNA expression in cervical cancer (Review). Oncol Rep (2014) 0.96
Interplay between DNA repair and inflammation, and the link to cancer. Crit Rev Biochem Mol Biol (2014) 0.96
Methylation-mediated transcriptional repression of microRNAs during cervical carcinogenesis. Epigenetics (2013) 0.94
Cross-species analysis of genic GC3 content and DNA methylation patterns. Genome Biol Evol (2013) 0.94
Epigenetic silencing of microRNA-149 in cancer-associated fibroblasts mediates prostaglandin E2/interleukin-6 signaling in the tumor microenvironment. Cell Res (2015) 0.93
CpG island hypermethylation-associated silencing of small nucleolar RNAs in human cancer. RNA Biol (2012) 0.92
Modulation of epigenetic targets for anticancer therapy: clinicopathological relevance, structural data and drug discovery perspectives. Curr Pharm Des (2013) 0.91
MicroRNA modulators of epigenetic regulation, the tumor microenvironment and the immune system in lung cancer. Mol Cancer (2015) 0.89
Risk factors and therapeutic targets in pancreatic cancer. Front Oncol (2013) 0.88
Epigenetic silencing of miR-145-5p contributes to brain metastasis. Oncotarget (2015) 0.88
MicroRNA expression profiling and DNA methylation signature for deregulated microRNA in cutaneous T-cell lymphoma. J Invest Dermatol (2014) 0.87
MicroRNA profiling of novel African American and Caucasian Prostate Cancer cell lines reveals a reciprocal regulatory relationship of miR-152 and DNA methyltranferase 1. Oncotarget (2014) 0.87
Silencing of miRNA-148a by hypermethylation activates the integrin-mediated signaling pathway in nasopharyngeal carcinoma. Oncotarget (2014) 0.87
The interaction between epigenetics, nutrition and the development of cancer. Nutrients (2015) 0.87
Impaired DICER1 function promotes stemness and metastasis in colon cancer. Oncogene (2013) 0.86
microRNAs: short non-coding bullets of gain of function mutant p53 proteins. Oncoscience (2014) 0.86
Systems biology of cancer: entropy, disorder, and selection-driven evolution to independence, invasion and "swarm intelligence". Cancer Metastasis Rev (2013) 0.86
DNA methylation mediated silencing of microRNA-145 is a potential prognostic marker in patients with lung adenocarcinoma. Sci Rep (2015) 0.85
Integrative identification of deregulated miRNA/TF-mediated gene regulatory loops and networks in prostate cancer. PLoS One (2014) 0.85
Regulatory role of small nucleolar RNAs in human diseases. Biomed Res Int (2015) 0.85
Non-Coding RNAs in Primary Liver Cancer. Front Med (Lausanne) (2015) 0.85
The potential of microRNAs in personalized medicine against cancers. Biomed Res Int (2014) 0.84
DNA Methylation of Tumor Suppressive miRNAs in Non-Hodgkin's Lymphomas. Front Genet (2012) 0.84
Interrelationship between microsatellite instability and microRNA in gastrointestinal cancer. World J Gastroenterol (2012) 0.84
Small RNA and its application in andrology and urology. Transl Androl Urol (2012) 0.84
Perspectives on epigenetic-based immune intervention for rheumatic diseases. Arthritis Res Ther (2013) 0.83
Oxidized low-density lipoprotein is a common risk factor for cardiovascular diseases and gastroenterological cancers via epigenomical regulation of microRNA-210. Oncotarget (2015) 0.83
Epigenetic silencing of monoallelically methylated miRNA loci in precancerous colorectal lesions. Oncogenesis (2013) 0.83
Targeted therapies in the treatment of advanced hepatocellular carcinoma. Clin Med Insights Oncol (2013) 0.83
DNA methylation dynamics in muscle development and disease. Front Aging Neurosci (2015) 0.83
Training-free atomistic prediction of nucleosome occupancy. Proc Natl Acad Sci U S A (2014) 0.83
Hepatitis B Virus X Protein Sensitizes TRAIL-Induced Hepatocyte Apoptosis by Inhibiting the E3 Ubiquitin Ligase A20. PLoS One (2015) 0.83
A novel approach to the discovery of survival biomarkers in glioblastoma using a joint analysis of DNA methylation and gene expression. Epigenetics (2014) 0.82
Methylation of miR-155-3p in mantle cell lymphoma and other non-Hodgkin's lymphomas. Oncotarget (2014) 0.82
Downregulation of IFNG in CD4(+) T cells in lung cancer through hypermethylation: a possible mechanism of tumor-induced immunosuppression. PLoS One (2013) 0.82
DNA Methylation mediated down-regulating of MicroRNA-33b and its role in gastric cancer. Sci Rep (2016) 0.82
Direct repression of the oncogene CDK4 by the tumor suppressor miR-486-5p in non-small cell lung cancer. Oncotarget (2016) 0.82
Kaiso, a transcriptional repressor, promotes cell migration and invasion of prostate cancer cells through regulation of miR-31 expression. Oncotarget (2016) 0.81
Epigenetic biomarkers: potential applications in gastrointestinal cancers. ISRN Gastroenterol (2014) 0.81
Global epigenetic regulation of microRNAs in multiple myeloma. PLoS One (2014) 0.80
Tumor Protein p63/microRNA Network in Epithelial Cancer Cells. Curr Genomics (2013) 0.80
MicroRNA expression patterns and signalling pathways in the development and progression of childhood solid tumours. Mol Cancer (2017) 0.79
L-methionase: a therapeutic enzyme to treat malignancies. Biomed Res Int (2014) 0.79
Nutrient-Gene Interaction in Colon Cancer, from the Membrane to Cellular Physiology. Annu Rev Nutr (2016) 0.79
miR-497 expression, function and clinical application in cancer. Oncotarget (2016) 0.79
General aspects of colorectal cancer. ISRN Oncol (2012) 0.79
Reversal of microRNA-150 silencing disadvantages crizotinib-resistant NPM-ALK(+) cell growth. J Clin Invest (2015) 0.78
UHRF1 promotes proliferation of gastric cancer via mediating tumor suppressor gene hypermethylation. Cancer Biol Ther (2015) 0.78
microRNA biomarkers in cystic diseases. BMB Rep (2013) 0.78
BRCA1 as a tumor suppressor linked to the regulation of epigenetic states: keeping oncomiRs under control. Breast Cancer Res (2012) 0.77
Hepatitis B virus X protein-mediated non-coding RNA aberrations in the development of human hepatocellular carcinoma. Exp Mol Med (2017) 0.77
The emerging role of miR-506 in cancer. Oncotarget (2016) 0.77
Epigenetic mechanisms in penile carcinoma. Int J Mol Sci (2013) 0.77
20(S)-Rg3 blocked epithelial-mesenchymal transition through DNMT3A/miR-145/FSCN1 in ovarian cancer. Oncotarget (2017) 0.77
Methylation-mediated molecular dysregulation in clinical oral malignancy. J Oncol (2012) 0.76
DDX3 Represses Stemness by Epigenetically Modulating Tumor-suppressive miRNAs in Hepatocellular Carcinoma. Sci Rep (2016) 0.76
Binding of 14-3-3 reader proteins to phosphorylated DNMT1 facilitates aberrant DNA methylation and gene expression. Nucleic Acids Res (2015) 0.76
Hypermethylation reduces the expression of PNPLA7 in hepatocellular carcinoma. Oncol Lett (2016) 0.75
Integration of genome scale data for identifying new players in colorectal cancer. World J Gastroenterol (2016) 0.75
DNMT1 mediates chemosensitivity by reducing methylation of miRNA-20a promoter in glioma cells. Exp Mol Med (2015) 0.75
Iodine-125 irradiation inhibits invasion of gastric cancer cells by reactivating microRNA-181c expression. Oncol Lett (2016) 0.75
Epigenetic Alterations in Parathyroid Cancers. Int J Mol Sci (2017) 0.75
Epigenetically regulated miR-145 suppresses colon cancer invasion and metastasis by targeting LASP1. Oncotarget (2016) 0.75
Clinical and biological significance of miR-23b and miR-193a in human hepatocellular carcinoma. Oncotarget (2016) 0.75
Anticancer Natural Compounds as Epigenetic Modulators of Gene Expression. Curr Genomics (2017) 0.75
Regulation of miR-200c and miR-141 by Methylation in Prostate Cancer. Prostate (2016) 0.75
MiR-193b promoter methylation accurately detects prostate cancer in urine sediments and miR-34b/c or miR-129-2 promoter methylation define subsets of clinically aggressive tumors. Mol Cancer (2017) 0.75
A primate-specific microRNA enters the lung cancer landscape. Proc Natl Acad Sci U S A (2013) 0.75
DNA Methylation Mediated Downregulation of miR-449c Controls Osteosarcoma Cell Cycle Progression by Directly Targeting Oncogene c-Myc. Int J Biol Sci (2017) 0.75
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell (2006) 120.51
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature (2007) 75.09
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature (1998) 72.56
MicroRNA expression profiles classify human cancers. Nature (2005) 69.12
Prediction of mammalian microRNA targets. Cell (2003) 53.70
Combinatorial microRNA target predictions. Nat Genet (2005) 50.48
A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci U S A (2006) 40.09
MicroRNA targeting specificity in mammals: determinants beyond seed pairing. Mol Cell (2007) 38.42
Most mammalian mRNAs are conserved targets of microRNAs. Genome Res (2008) 37.16
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat Cell Biol (2007) 37.10
A conserved AU sequence from the 3' untranslated region of GM-CSF mRNA mediates selective mRNA degradation. Cell (1986) 36.96
The nuclear RNase III Drosha initiates microRNA processing. Nature (2003) 35.49
Circulating microRNAs as stable blood-based markers for cancer detection. Proc Natl Acad Sci U S A (2008) 33.65
Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci U S A (2002) 32.26
A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science (2001) 31.33
The epigenomics of cancer. Cell (2007) 30.91
RAS is regulated by the let-7 microRNA family. Cell (2005) 30.24
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc Natl Acad Sci U S A (2004) 28.29
RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev (2001) 26.16
A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemia. N Engl J Med (2005) 26.02
Argonaute2 is the catalytic engine of mammalian RNAi. Science (2004) 22.86
MicroRNA genes are transcribed by RNA polymerase II. EMBO J (2004) 20.65
Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival. Cancer Res (2004) 18.86
Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype? Nat Rev Cancer (2007) 18.69
The Microprocessor complex mediates the genesis of microRNAs. Nature (2004) 17.70
Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev (2003) 17.64
Epigenetics in cancer. N Engl J Med (2008) 17.36
Micro RNAs are complementary to 3' UTR sequence motifs that mediate negative post-transcriptional regulation. Nat Genet (2002) 17.20
Switching from repression to activation: microRNAs can up-regulate translation. Science (2007) 17.00
The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2. Genes Dev (2008) 15.01
Endogenous human microRNAs that suppress breast cancer metastasis. Nature (2008) 14.37
Inhibition of translational initiation by Let-7 MicroRNA in human cells. Science (2005) 13.84
A coding-independent function of gene and pseudogene mRNAs regulates tumour biology. Nature (2010) 13.82
Identification of virus-encoded microRNAs. Science (2004) 12.56
Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex. Cell (2006) 11.98
Widespread microRNA repression by Myc contributes to tumorigenesis. Nat Genet (2007) 10.78
A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells. EMBO Rep (2008) 10.71
Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma. Proc Natl Acad Sci U S A (2011) 10.56
MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. Proc Natl Acad Sci U S A (2007) 9.82
RNA editing by adenosine deaminases that act on RNA. Annu Rev Biochem (2001) 9.66
Hypomethylation distinguishes genes of some human cancers from their normal counterparts. Nature (1983) 9.28
Involvement of microRNA in AU-rich element-mediated mRNA instability. Cell (2005) 9.01
Dicer, Drosha, and outcomes in patients with ovarian cancer. N Engl J Med (2008) 8.77
RNAi-mediated targeting of heterochromatin by the RITS complex. Science (2004) 8.73
Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells. Cancer Cell (2006) 8.46
microRNAs exhibit high frequency genomic alterations in human cancer. Proc Natl Acad Sci U S A (2006) 8.24
MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells. Cell (2009) 8.14
Regulation of serotonin-2C receptor G-protein coupling by RNA editing. Nature (1997) 7.92
Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster. Nat Genet (2006) 7.53
Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome. Epigenetics (2011) 7.38
Functionality or transcriptional noise? Evidence for selection within long noncoding RNAs. Genome Res (2007) 7.34
MicroRNAs accurately identify cancer tissue origin. Nat Biotechnol (2008) 7.27
A microRNA DNA methylation signature for human cancer metastasis. Proc Natl Acad Sci U S A (2008) 7.14
Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest. Cell Cycle (2007) 7.00
Does the ribosome translate cancer? Nat Rev Cancer (2003) 6.89
RNA polymerase III transcribes human microRNAs. Nat Struct Mol Biol (2006) 6.81
MicroRNA-10a binds the 5'UTR of ribosomal protein mRNAs and enhances their translation. Mol Cell (2008) 6.58
Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends. Science (2007) 6.33
miR-34a repression of SIRT1 regulates apoptosis. Proc Natl Acad Sci U S A (2008) 6.24
miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells. BMC Med (2008) 5.91
Cancer epigenetics reaches mainstream oncology. Nat Med (2011) 5.83
RNAi: nature abhors a double-strand. Curr Opin Genet Dev (2002) 5.74
OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma. Nature (2010) 5.73
Genetic unmasking of an epigenetically silenced microRNA in human cancer cells. Cancer Res (2007) 5.62
Relation between microRNA expression and progression and prognosis of gastric cancer: a microRNA expression analysis. Lancet Oncol (2009) 5.56
Circulating microRNA in body fluid: a new potential biomarker for cancer diagnosis and prognosis. Cancer Sci (2010) 5.17
miR-19 is a key oncogenic component of mir-17-92. Genes Dev (2009) 4.95
N-myc enhances the expression of a large set of genes functioning in ribosome biogenesis and protein synthesis. EMBO J (2001) 4.85
A MicroRNA targeting dicer for metastasis control. Cell (2010) 4.81
Silencing of microRNA families by seed-targeting tiny LNAs. Nat Genet (2011) 4.81
let-7 microRNA functions as a potential growth suppressor in human colon cancer cells. Biol Pharm Bull (2006) 4.42
Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer. Cell Cycle (2008) 4.35
MiR-15a and miR-16-1 cluster functions in human leukemia. Proc Natl Acad Sci U S A (2008) 4.33
Exploration of tumor-suppressive microRNAs silenced by DNA hypermethylation in oral cancer. Cancer Res (2008) 4.19
miR-328 functions as an RNA decoy to modulate hnRNP E2 regulation of mRNA translation in leukemic blasts. Cell (2010) 4.07
Genetic and epigenetic silencing of microRNA-203 enhances ABL1 and BCR-ABL1 oncogene expression. Cancer Cell (2008) 4.01
Phosphorylation of the human microRNA-generating complex mediates MAPK/Erk signaling. Cell (2009) 3.90
Retracted A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function. Nat Genet (2009) 3.88
Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer. Cancer Res (2008) 3.81
RNA silencing: the genome's immune system. Science (2002) 3.66
Genetic variants of miRNA sequences and non-small cell lung cancer survival. J Clin Invest (2008) 3.53
miR-124 and miR-203 are epigenetically silenced tumor-suppressive microRNAs in hepatocellular carcinoma. Carcinogenesis (2009) 3.45
Epigenetic inactivation of microRNA gene hsa-mir-9-1 in human breast cancer. J Pathol (2008) 3.18
Methylation mediated silencing of MicroRNA-1 gene and its role in hepatocellular carcinogenesis. Cancer Res (2008) 3.16
Aberrant epigenetic landscape in cancer: how cellular identity goes awry. Dev Cell (2010) 2.86
A genetic defect in exportin-5 traps precursor microRNAs in the nucleus of cancer cells. Cancer Cell (2010) 2.78
Epigenetic regulation of microRNA expression in colorectal cancer. Int J Cancer (2009) 2.62
Role for DNA methylation in the regulation of miR-200c and miR-141 expression in normal and cancer cells. PLoS One (2010) 2.55
Potential role of miR-9 and miR-223 in recurrent ovarian cancer. Mol Cancer (2008) 2.53
Coordinated epigenetic repression of the miR-200 family and miR-205 in invasive bladder cancer. Int J Cancer (2011) 2.49
Hypermethylation of let-7a-3 in epithelial ovarian cancer is associated with low insulin-like growth factor-II expression and favorable prognosis. Cancer Res (2007) 2.45
Proteomic analysis of melanoma-derived exosomes by two-dimensional polyacrylamide gel electrophoresis and mass spectrometry. Proteomics (2004) 2.43
Dynamic epigenetic regulation of the microRNA-200 family mediates epithelial and mesenchymal transitions in human tumorigenesis. Oncogene (2011) 2.42
Altered MicroRNA expression in cervical carcinomas. Clin Cancer Res (2008) 2.42
miR-34a as a prognostic marker of relapse in surgically resected non-small-cell lung cancer. Carcinogenesis (2009) 2.41
Genome-wide profiling of methylated promoters in pancreatic adenocarcinoma. Cancer Biol Ther (2008) 2.38
Evidence that homologous X-chromosome pairing requires transcription and Ctcf protein. Nat Genet (2007) 2.35
Regulation of IKKbeta by miR-199a affects NF-kappaB activity in ovarian cancer cells. Oncogene (2008) 2.31
Gap junction-mediated import of microRNA from bone marrow stromal cells can elicit cell cycle quiescence in breast cancer cells. Cancer Res (2011) 2.31
Epigenetic silencing of the intronic microRNA hsa-miR-342 and its host gene EVL in colorectal cancer. Oncogene (2008) 2.26
Gene-expression profiles in hereditary breast cancer. N Engl J Med (2001) 29.80
Inactivation of the apoptosis effector Apaf-1 in malignant melanoma. Nature (2001) 4.99
Frequent inactivation of PTEN/MMAC1 in primary prostate cancer. Cancer Res (1997) 4.73
Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer. Hum Mol Genet (2001) 3.96
Epigenetic inactivation of the Wnt antagonist DICKKOPF-1 (DKK-1) gene in human colorectal cancer. Oncogene (2006) 2.69
Dynamic epigenetic regulation of the microRNA-200 family mediates epithelial and mesenchymal transitions in human tumorigenesis. Oncogene (2011) 2.42
Molecular detection of tumor cells in bronchoalveolar lavage fluid from patients with early stage lung cancer. J Natl Cancer Inst (1999) 2.34
Identification of a mononucleotide repeat as a major target for mitochondrial DNA alterations in human tumors. Cancer Res (2001) 2.10
Hypermethylation of the hMLH1 gene promoter in human gastric cancers with microsatellite instability. Cancer Res (1999) 2.09
Gene promoter hypermethylation in tumors and serum of head and neck cancer patients. Cancer Res (2000) 1.91
Salermide, a Sirtuin inhibitor with a strong cancer-specific proapoptotic effect. Oncogene (2008) 1.78
Transcriptional silencing of the p73 gene in acute lymphoblastic leukemia and Burkitt's lymphoma is associated with 5' CpG island methylation. Cancer Res (1999) 1.69
CpG island hypermethylation-associated silencing of non-coding RNAs transcribed from ultraconserved regions in human cancer. Oncogene (2010) 1.65
Molecular detection of prostate cancer in urine by GSTP1 hypermethylation. Clin Cancer Res (2001) 1.63
Late Crohn's disease patients present an increase in peripheral Th17 cells and cytokine production compared with early patients. Aliment Pharmacol Ther (2009) 1.62
The PDGFRβ-AKT pathway contributes to CDDP-acquired resistance in testicular germ cell tumors. Clin Cancer Res (2013) 1.47
Point mutation and homozygous deletion of PTEN/MMAC1 in primary bladder cancers. Oncogene (1998) 1.36
Epigenetic regulation of telomeres in human cancer. Oncogene (2008) 1.33
Silencing of Kruppel-like factor 2 by the histone methyltransferase EZH2 in human cancer. Oncogene (2011) 1.31
Proteins that bind methylated DNA and human cancer: reading the wrong words. Br J Cancer (2008) 1.27
The dioxin receptor is silenced by promoter hypermethylation in human acute lymphoblastic leukemia through inhibition of Sp1 binding. Carcinogenesis (2006) 1.25
NID2 and HOXA9 promoter hypermethylation as biomarkers for prevention and early detection in oral cavity squamous cell carcinoma tissues and saliva. Cancer Prev Res (Phila) (2011) 1.21
Hypermethylation of the hMLH1 gene promoter is associated with microsatellite instability in early human gastric neoplasia. Oncogene (2001) 1.17
The chromatin remodeling factor CHD8 interacts with elongating RNA polymerase II and controls expression of the cyclin E2 gene. Nucleic Acids Res (2009) 1.16
Antitumor activity of a small-molecule inhibitor of the histone kinase Haspin. Oncogene (2011) 1.13
Identification of DNA hypermethylation of SOX9 in association with bladder cancer progression using CpG microarrays. Br J Cancer (2007) 1.12
Specific hypermethylation of LINE-1 elements during abnormal overgrowth and differentiation of human placenta. Oncogene (2006) 1.11
Novel epigenetically deregulated genes in testicular cancer include homeobox genes and SCGB3A1 (HIN-1). J Pathol (2006) 1.10
Microsatellite instability in inflammatory bowel disease-associated neoplastic lesions is associated with hypermethylation and diminished expression of the DNA mismatch repair gene, hMLH1. Cancer Res (2000) 1.10
Unmasking of epigenetically silenced candidate tumor suppressor genes by removal of methyl-CpG-binding domain proteins. Oncogene (2008) 1.07
Viral epigenomes in human tumorigenesis. Oncogene (2010) 1.06
5'-CpG island methylation of the LKB1/STK11 promoter and allelic loss at chromosome 19p13.3 in sporadic colorectal cancer. Gut (2000) 1.04
Increased loss of chromosome 9p21 but not p16 inactivation in primary non-small cell lung cancer from smokers. Cancer Res (2001) 0.98
Impaired recruitment of the histone methyltransferase DOT1L contributes to the incomplete reactivation of tumor suppressor genes upon DNA demethylation. Oncogene (2009) 0.97
Molecular detection of neoplastic cells in lymph nodes of metastatic colorectal cancer patients predicts recurrence. Clin Cancer Res (1999) 0.97
Transforming pathways unleashed by a HDAC2 mutation in human cancer. Oncogene (2008) 0.93
Genetic and epigenetic profile of sporadic pheochromocytomas. J Med Genet (2004) 0.90
Epigenetic control of nuclear architecture. Cell Mol Life Sci (2007) 0.90
Multiple binding of methyl-CpG and polycomb proteins in long-term gene silencing events. J Cell Physiol (2007) 0.89
Epigenetic inactivation of the ERK inhibitor Spry2 in B-cell diffuse lymphomas. Oncogene (2008) 0.88
Global DNA methylation: a common early event in oral cancer cases with exposure to environmental carcinogens or viral agents. P R Health Sci J (2009) 0.87
DNA methylation determines nucleosome occupancy in the 5'-CpG islands of tumor suppressor genes. Oncogene (2013) 0.86
Checkpoint kinase 1 (CHK1) protein and mRNA expression is downregulated in aggressive variants of human lymphoid neoplasms. Leukemia (2005) 0.85
Merkel cell carcinoma of the vulva. Gynecol Oncol (1997) 0.83
Aberrant epigenetic landscape in intellectual disability. Prog Brain Res (2012) 0.81
Identification of (1H)-pyrroles as histone deacetylase inhibitors with antitumoral activity. Oncogene (2009) 0.78
Towards defining the lymphoma methylome. Leukemia (2006) 0.78
Gene amplification-associated overexpression of the RNA editing enzyme ADAR1 enhances human lung tumorigenesis. Oncogene (2016) 0.78
Loss of chromosome arms 3p and 9p and inactivation of P16 (INK4a) in normal epithelium of patients with primary lung cancer. Genes Chromosomes Cancer (2001) 0.76
Epigenetic silencing of E- and N-cadherins in the stroma of mouse thymic lymphomas. Carcinogenesis (2005) 0.76
[Introduction to molecular biology of endometrial cancer]. Med Clin (Barc) (1996) 0.75
DNMT3A mutations mediate the epigenetic reactivation of the leukemogenic factor MEIS1 in acute myeloid leukemia. Oncogene (2017) 0.75