Published in J Exp Med on December 20, 2004
ICAM-1 regulates neutrophil adhesion and transcellular migration of TNF-alpha-activated vascular endothelium under flow. Blood (2005) 3.26
The neutrophil in vascular inflammation. Nat Med (2011) 2.84
Mechanisms of leukocyte transendothelial migration. Annu Rev Pathol (2011) 2.70
Mechanisms of transendothelial migration of leukocytes. Circ Res (2009) 2.14
The multifaceted functions of neutrophils. Annu Rev Pathol (2013) 1.97
Opening the flood-gates: how neutrophil-endothelial interactions regulate permeability. Trends Immunol (2009) 1.82
Impaired integrin-dependent function in Wiskott-Aldrich syndrome protein-deficient murine and human neutrophils. Immunity (2006) 1.79
Emerging mechanisms of neutrophil recruitment across endothelium. Trends Immunol (2011) 1.65
Leukocyte-endothelial interactions in inflammation. J Cell Mol Med (2009) 1.51
p120-Catenin regulates leukocyte transmigration through an effect on VE-cadherin phosphorylation. Blood (2008) 1.48
How leukocytes cross the vascular endothelium. Nat Rev Immunol (2015) 1.44
Leukocyte transmigration requires kinesin-mediated microtubule-dependent membrane trafficking from the lateral border recycling compartment. J Exp Med (2008) 1.43
Transcellular migration of leukocytes is mediated by the endothelial lateral border recycling compartment. J Exp Med (2009) 1.42
Intermediate-affinity LFA-1 binds alpha-actinin-1 to control migration at the leading edge of the T cell. EMBO J (2007) 1.39
Mechanisms and consequences of neutrophil interaction with the endothelium. Am J Pathol (2007) 1.38
Uropod elongation is a common final step in leukocyte extravasation through inflamed vessels. J Exp Med (2012) 1.33
Junctional adhesion molecule-A-deficient polymorphonuclear cells show reduced diapedesis in peritonitis and heart ischemia-reperfusion injury. Proc Natl Acad Sci U S A (2005) 1.33
Endothelial signaling in paracellular and transcellular leukocyte transmigration. Front Biosci (Landmark Ed) (2009) 1.31
Intravital 2-photon imaging of leukocyte trafficking in beating heart. J Clin Invest (2012) 1.28
Neutrophil recruitment under shear flow: it's all about endothelial cell rings and gaps. Microcirculation (2009) 1.26
Protein kinase C theta regulates stability of the peripheral adhesion ring junction and contributes to the sensitivity of target cell lysis by CTL. J Immunol (2008) 1.24
Endothelial cell junctions and the regulation of vascular permeability and leukocyte transmigration. J Thromb Haemost (2008) 1.23
Monocyte maturation, HIV susceptibility, and transmigration across the blood brain barrier are critical in HIV neuropathogenesis. J Leukoc Biol (2012) 1.22
Dynamic shifts in LFA-1 affinity regulate neutrophil rolling, arrest, and transmigration on inflamed endothelium. Blood (2005) 1.22
How endothelial cells regulate transmigration of leukocytes in the inflammatory response. Am J Pathol (2014) 1.21
Novel aspects in the regulation of the leukocyte adhesion cascade. Thromb Haemost (2009) 1.11
Neisseria meningitidis infection of human endothelial cells interferes with leukocyte transmigration by preventing the formation of endothelial docking structures. J Cell Biol (2006) 1.10
Leukocyte integrins: role in leukocyte recruitment and as therapeutic targets in inflammatory disease. Pharmacol Ther (2014) 1.08
The extracellular adherence protein (Eap) of Staphylococcus aureus inhibits wound healing by interfering with host defense and repair mechanisms. Blood (2005) 1.07
Endothelial CD47 interaction with SIRPgamma is required for human T-cell transendothelial migration under shear flow conditions in vitro. Blood (2008) 1.05
Rho-GTPase signaling in leukocyte extravasation: an endothelial point of view. Cell Adh Migr (2014) 1.03
Endothelial reticulon-4B (Nogo-B) regulates ICAM-1-mediated leukocyte transmigration and acute inflammation. Blood (2010) 1.03
Getting leukocytes to the site of inflammation. Vet Pathol (2013) 1.03
Assays of transendothelial migration in vitro. Methods Enzymol (2008) 1.00
Evaluation of soluble junctional adhesion molecule-A as a biomarker of human brain endothelial barrier breakdown. PLoS One (2010) 1.00
Mechanisms of neutrophil transendothelial migration. Front Biosci (Landmark Ed) (2009) 0.98
Neutrophil and monocyte recruitment by PECAM, CD99, and other molecules via the LBRC. Semin Immunopathol (2013) 0.97
Structural determinants of Junctional Adhesion Molecule A (JAM-A) function and mechanisms of intracellular signaling. Curr Opin Cell Biol (2009) 0.96
The Rho-guanine nucleotide exchange factor Trio controls leukocyte transendothelial migration by promoting docking structure formation. Mol Biol Cell (2012) 0.96
Benzo[a]pyrene induces intercellular adhesion molecule-1 through a caveolae and aryl hydrocarbon receptor mediated pathway. Toxicol Appl Pharmacol (2008) 0.92
Transmigration of neutrophils across inflamed endothelium is signaled through LFA-1 and Src family kinase. J Immunol (2008) 0.91
The regulation of transendothelial migration: new knowledge and new questions. Cardiovasc Res (2015) 0.91
Intercellular adhesion molecules (ICAMs) and spermatogenesis. Hum Reprod Update (2013) 0.90
Tetraspanin CD9 links junctional adhesion molecule-A to αvβ3 integrin to mediate basic fibroblast growth factor-specific angiogenic signaling. Mol Biol Cell (2013) 0.90
Pathogenesis of meningococcemia. Cold Spring Harb Perspect Med (2013) 0.90
PECAM-1 engagement counteracts ICAM-1-induced signaling in brain vascular endothelial cells. J Neurochem (2007) 0.89
Mechanism of meningeal invasion by Neisseria meningitidis. Virulence (2012) 0.89
Lovastatin delays infection and increases survival rates in AG129 mice infected with dengue virus serotype 2. PLoS One (2014) 0.86
Relocalization of junctional adhesion molecule A during inflammatory stimulation of brain endothelial cells. Mol Cell Biol (2012) 0.86
p120-Catenin prevents neutrophil transmigration independently of RhoA inhibition by impairing Src dependent VE-cadherin phosphorylation. Am J Physiol Cell Physiol (2012) 0.85
CXCL1-triggered interaction of LFA1 and ICAM1 control glucose-induced leukocyte recruitment during inflammation in vivo. Mediators Inflamm (2012) 0.85
Thermal facilitation of lymphocyte trafficking involves temporal induction of intravascular ICAM-1. Microcirculation (2008) 0.83
TNF-α and IFN-γ promote lymphocyte adhesion to endothelial junctional regions facilitating transendothelial migration. J Leukoc Biol (2013) 0.82
Neutrophil migration into the placenta: Good, bad or deadly? Cell Adh Migr (2016) 0.81
Leukocyte rolling and adhesion via ICAM-1 signals to endothelial permeability. Focus on "Leukocyte rolling and adhesion both contribute to regulation of microvascular permeability to albumin via ligation of ICAM-1". Am J Physiol Cell Physiol (2011) 0.81
Real-time imaging of Toxoplasma-infected human monocytes under fluidic shear stress reveals rapid translocation of intracellular parasites across endothelial barriers. Cell Microbiol (2013) 0.80
Group V phospholipase A2 in bone marrow-derived myeloid cells and bronchial epithelial cells promotes bacterial clearance after Escherichia coli pneumonia. J Biol Chem (2011) 0.78
Cortactin regulates the activity of small GTPases and ICAM-1 clustering in endothelium: Implications for the formation of docking structures. Tissue Barriers (2013) 0.78
Plasticity of blood- and lymphatic endothelial cells and marker identification. PLoS One (2013) 0.77
Glycocalyx Degradation Induces a Proinflammatory Phenotype and Increased Leukocyte Adhesion in Cultured Endothelial Cells under Flow. PLoS One (2016) 0.77
N-glycosylation controls the function of junctional adhesion molecule-A. Mol Biol Cell (2015) 0.77
Epithelium-Specific Ets-Like Transcription Factor 1, ESE-1, Regulates ICAM-1 Expression in Cultured Lung Epithelial Cell Lines. Mediators Inflamm (2015) 0.76
Mechanism of Diapedesis: Importance of the Transcellular Route. Adv Immunol (2015) 0.75
Abnormal cannabidiol attenuates experimental colitis in mice, promotes wound healing and inhibits neutrophil recruitment. J Inflamm (Lond) (2016) 0.75
Leukocyte transcellular diapedesis: Rap1b is in control. Tissue Barriers (2015) 0.75
Transendothelial migration: unifying principles from the endothelial perspective. Immunol Rev (2016) 0.75
Assessing leukocyte-endothelial interactions under flow conditions in an ex vivo autoperfused microflow chamber assay. J Vis Exp (2014) 0.75
Modification of Gene Expression, Proliferation, and Function of OP9 Stroma Cells by Bcr-Abl-Expressing Leukemia Cells. PLoS One (2015) 0.75
T cell regulation through a basic suppressive mechanism targeting low density lipoprotein receptor-related protein 1. Immunology (2017) 0.75
From leukocyte recruitment to resolution of inflammation: the cardinal role of integrins. J Leukoc Biol (2017) 0.75
Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell (1994) 27.85
Cooperative interactions of LFA-1 and Mac-1 with intercellular adhesion molecule-1 in facilitating adherence and transendothelial migration of human neutrophils in vitro. J Clin Invest (1989) 5.97
Junction adhesion molecule is a receptor for reovirus. Cell (2001) 4.00
Leukocyte-endothelial-cell interactions in leukocyte transmigration and the inflammatory response. Trends Immunol (2003) 3.91
RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1. Nat Immunol (2003) 3.91
Relative contribution of LFA-1 and Mac-1 to neutrophil adhesion and migration. J Immunol (1999) 3.67
Integrin avidity regulation: are changes in affinity and conformation underemphasized? Curr Opin Cell Biol (2003) 3.59
JAM-1 is a ligand of the beta(2) integrin LFA-1 involved in transendothelial migration of leukocytes. Nat Immunol (2002) 3.17
Dynamic interaction of VCAM-1 and ICAM-1 with moesin and ezrin in a novel endothelial docking structure for adherent leukocytes. J Cell Biol (2002) 3.16
Monocyte rolling, arrest and spreading on IL-4-activated vascular endothelium under flow is mediated via sequential action of L-selectin, beta 1-integrins, and beta 2-integrins. J Cell Biol (1994) 3.02
Real-time imaging of vascular endothelial-cadherin during leukocyte transmigration across endothelium. J Immunol (2001) 2.40
Rap1 translates chemokine signals to integrin activation, cell polarization, and motility across vascular endothelium under flow. J Cell Biol (2003) 2.40
Adhesion-activating phorbol ester increases the mobility of leukocyte integrin LFA-1 in cultured lymphocytes. J Clin Invest (1996) 2.25
Membranes as messengers in T cell adhesion signaling. Nat Immunol (2004) 2.02
Endothelial cells proactively form microvilli-like membrane projections upon intercellular adhesion molecule 1 engagement of leukocyte LFA-1. J Immunol (2003) 1.95
Crucial importance of PKC-beta(I) in LFA-1-mediated locomotion of activated T cells. Nat Immunol (2001) 1.94
Neutrophil transendothelial migration is independent of tight junctions and occurs preferentially at tricellular corners. J Immunol (1997) 1.84
Dynamic regulation of LFA-1 activation and neutrophil arrest on intercellular adhesion molecule 1 (ICAM-1) in shear flow. J Biol Chem (2002) 1.62
The use of lymphocyte function-associated antigen (LFA)-1-deficient mice to determine the role of LFA-1, Mac-1, and alpha4 integrin in the inflammatory response of neutrophils. J Exp Med (2001) 1.59
Monocytes induce reversible focal changes in vascular endothelial cadherin complex during transendothelial migration under flow. J Cell Biol (2000) 1.55
Analysis of tight junctions during neutrophil transendothelial migration. J Cell Sci (2000) 1.47
Random locomotion and chemotaxis of human blood polymorphonuclear leukocytes (PMN) in the presence of EDTA: PMN in close quarters require neither leukocyte integrins nor external divalent cations. Proc Natl Acad Sci U S A (1997) 1.43
Effects of human neutrophil chemotaxis across human endothelial cell monolayers on the permeability of these monolayers to ions and macromolecules. J Cell Physiol (1988) 1.42
Leukocyte transendothelial migration: a junctional affair. Semin Immunol (2002) 1.39
Important contributions of P-selectin glycoprotein ligand-1-mediated secondary capture to human monocyte adhesion to P-selectin, E-selectin, and TNF-alpha-activated endothelium under flow in vitro. J Immunol (1998) 1.31
The role of endothelial cell lateral junctions during leukocyte trafficking. Immunol Rev (2002) 1.22
Characterization of a monoclonal antibody-defined human melanoma-associated antigen susceptible to induction by immune interferon. J Immunol (1987) 1.18
Rap1-mediated lymphocyte function-associated antigen-1 activation by the T cell antigen receptor is dependent on phospholipase C-gamma1. J Biol Chem (2003) 1.16
Preferential sites for stationary adhesion of neutrophils to cytokine-stimulated HUVEC under flow conditions. J Leukoc Biol (2000) 1.13
L-selectin shedding does not regulate human neutrophil attachment, rolling, or transmigration across human vascular endothelium in vitro. J Immunol (1997) 1.10
Tumor necrosis factor-alpha-induced leukocyte adhesion and microvessel permeability. Am J Physiol Heart Circ Physiol (2002) 1.09
Prolonged cytokine exposure causes a dynamic redistribution of endothelial cell adhesion molecules to intercellular junctions. Lab Invest (1996) 0.86
Ly-6Chi monocytes dominate hypercholesterolemia-associated monocytosis and give rise to macrophages in atheromata. J Clin Invest (2007) 8.65
Single-cell exome sequencing and monoclonal evolution of a JAK2-negative myeloproliferative neoplasm. Cell (2012) 5.16
Prognostic or predictive plasma cytokines and angiogenic factors for patients treated with pazopanib for metastatic renal-cell cancer: a retrospective analysis of phase 2 and phase 3 trials. Lancet Oncol (2012) 4.58
Incidence of treated cardiac arrest in hospitalized patients in the United States. Crit Care Med (2011) 4.43
Proinflammatory cytokines disrupt epithelial barrier function by apoptosis-independent mechanisms. J Immunol (2003) 4.00
A JNK-dependent pathway is required for TNFalpha-induced apoptosis. Cell (2003) 3.90
A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity. Nature (2010) 3.84
KLF2 Is a novel transcriptional regulator of endothelial proinflammatory activation. J Exp Med (2004) 3.69
High-speed graphene transistors with a self-aligned nanowire gate. Nature (2010) 3.48
Geographic variation in cardiovascular procedure use among Medicare fee-for-service vs Medicare Advantage beneficiaries. JAMA (2013) 3.30
ICAM-1 regulates neutrophil adhesion and transcellular migration of TNF-alpha-activated vascular endothelium under flow. Blood (2005) 3.26
Novel mechanism of lapatinib resistance in HER2-positive breast tumor cells: activation of AXL. Cancer Res (2009) 3.10
Influenza-associated hospitalization in a subtropical city. PLoS Med (2006) 3.07
OGG1 initiates age-dependent CAG trinucleotide expansion in somatic cells. Nature (2007) 3.03
Fractalkine preferentially mediates arrest and migration of CD16+ monocytes. J Exp Med (2003) 3.02
Retracted Phosphatidylinositol 3-kinase/Akt pathway regulates tuberous sclerosis tumor suppressor complex by phosphorylation of tuberin. J Biol Chem (2002) 2.97
T-bet is required for optimal proinflammatory CD4+ T-cell trafficking. Blood (2005) 2.95
Identification of an angiogenic factor that when mutated causes susceptibility to Klippel-Trenaunay syndrome. Nature (2004) 2.90
Identification of molecular characteristics correlated with glioblastoma sensitivity to EGFR kinase inhibition through use of an intracranial xenograft test panel. Mol Cancer Ther (2007) 2.89
The nuclear receptor Nr5a2 can replace Oct4 in the reprogramming of murine somatic cells to pluripotent cells. Cell Stem Cell (2010) 2.89
Coronary revascularization trends in the United States, 2001-2008. JAMA (2011) 2.81
Endocytosis of epithelial apical junctional proteins by a clathrin-mediated pathway into a unique storage compartment. Mol Biol Cell (2003) 2.76
JAM-A regulates permeability and inflammation in the intestine in vivo. J Exp Med (2007) 2.63
Mechanism of IFN-gamma-induced endocytosis of tight junction proteins: myosin II-dependent vacuolarization of the apical plasma membrane. Mol Biol Cell (2005) 2.46
Activation and overexpression of centrosome kinase BTAK/Aurora-A in human ovarian cancer. Clin Cancer Res (2003) 2.43
Third- and fourth-degree perineal lacerations: defining high-risk clinical clusters. Am J Obstet Gynecol (2011) 2.42
Interferon-gamma regulates intestinal epithelial homeostasis through converging beta-catenin signaling pathways. Immunity (2010) 2.39
Commuting and health in Cambridge: a study of a 'natural experiment' in the provision of new transport infrastructure. BMC Public Health (2010) 2.31
Differential roles for actin polymerization and a myosin II motor in assembly of the epithelial apical junctional complex. Mol Biol Cell (2005) 2.31
TLR signaling mediated by MyD88 is required for a protective innate immune response by neutrophils to Citrobacter rodentium. J Immunol (2007) 2.27
Invasive Escherichia coli are a feature of Crohn's disease. Lab Invest (2007) 2.27
Interferon-gamma induces internalization of epithelial tight junction proteins via a macropinocytosis-like process. FASEB J (2005) 2.17
Cytokine regulation of tight junctions. Biochim Biophys Acta (2008) 2.16
Algal genomes reveal evolutionary mosaicism and the fate of nucleomorphs. Nature (2012) 2.15
Endothelial-dependent mechanisms of leukocyte recruitment to the vascular wall. Circ Res (2007) 2.15
Nuclear factor high-mobility group box1 mediating the activation of Toll-like receptor 4 signaling in hepatocytes in the early stage of nonalcoholic fatty liver disease in mice. Hepatology (2011) 2.13
Aurora-A abrogation of p53 DNA binding and transactivation activity by phosphorylation of serine 215. J Biol Chem (2004) 2.11
Peptidomimetic targeting of critical androgen receptor-coregulator interactions in prostate cancer. Nat Commun (2013) 2.11
Robust segmentation of overlapping cells in histopathology specimens using parallel seed detection and repulsive level set. IEEE Trans Biomed Eng (2011) 2.08
CX3CR1 regulates intestinal macrophage homeostasis, bacterial translocation, and colitogenic Th17 responses in mice. J Clin Invest (2011) 2.08
Cleavage specificity of Saccharomyces cerevisiae flap endonuclease 1 suggests a double-flap structure as the cellular substrate. J Biol Chem (2002) 2.06
Low prevalence of knee and back pain in southeast China; the Shantou COPCORD study. J Rheumatol (2004) 2.06
Efficacy and safety of omega-3 fatty acids for the prevention of atrial fibrillation: a meta-analysis. Can J Cardiol (2012) 2.06
Role for actin filament turnover and a myosin II motor in cytoskeleton-driven disassembly of the epithelial apical junctional complex. Mol Biol Cell (2004) 2.05
Framing Financial Incentives to Increase Physical Activity Among Overweight and Obese Adults: A Randomized, Controlled Trial. Ann Intern Med (2016) 1.96
Therapeutic misconception, misestimation, and optimism in participants enrolled in phase 1 trials. Cancer (2012) 1.94
Biosynthesis of the salinosporamide A polyketide synthase substrate chloroethylmalonyl-coenzyme A from S-adenosyl-L-methionine. Proc Natl Acad Sci U S A (2009) 1.91
Suppression versus induction of androgen receptor functions by the phosphatidylinositol 3-kinase/Akt pathway in prostate cancer LNCaP cells with different passage numbers. J Biol Chem (2003) 1.90
Junctional adhesion molecule 1 regulates epithelial cell morphology through effects on beta1 integrins and Rap1 activity. J Biol Chem (2005) 1.89
Proarrhythmic risk of embryonic stem cell-derived cardiomyocyte transplantation in infarcted myocardium. Heart Rhythm (2010) 1.89
DNAshape: a method for the high-throughput prediction of DNA structural features on a genomic scale. Nucleic Acids Res (2013) 1.86
Human papillomavirus infection and bladder cancer risk: a meta-analysis. J Infect Dis (2011) 1.81
Cytoskeletal regulation of epithelial barrier function during inflammation. Am J Pathol (2010) 1.73
AKT/PKB signaling mechanisms in cancer and chemoresistance. Front Biosci (2005) 1.72
Highly efficient gate-tunable photocurrent generation in vertical heterostructures of layered materials. Nat Nanotechnol (2013) 1.72
A unique role for nonmuscle myosin heavy chain IIA in regulation of epithelial apical junctions. PLoS One (2007) 1.72
Role of the intestinal barrier in inflammatory bowel disease. World J Gastroenterol (2008) 1.72
Inactivation of Brca2 promotes Trp53-associated but inhibits KrasG12D-dependent pancreatic cancer development in mice. Gastroenterology (2011) 1.70
Structure of transmembrane pore induced by Bax-derived peptide: evidence for lipidic pores. Proc Natl Acad Sci U S A (2008) 1.70
Constitutive activation of Rho proteins by CNF-1 influences tight junction structure and epithelial barrier function. J Cell Sci (2003) 1.70
Histone H3 as a novel substrate for MAP kinase phosphatase-1. Am J Physiol Cell Physiol (2008) 1.68
Age-specific effects of hormone therapy use on overall mortality and ischemic heart disease mortality among women in the California Teachers Study. Menopause (2011) 1.67
RhoA, Rac1, and Cdc42 exert distinct effects on epithelial barrier via selective structural and biochemical modulation of junctional proteins and F-actin. Am J Physiol Cell Physiol (2004) 1.65
Effect of continuous compressions and 30:2 cardiopulmonary resuscitation on global ventilation/perfusion values during resuscitation in a porcine model. Crit Care Med (2010) 1.65
Signal regulatory protein (SIRPalpha), a cellular ligand for CD47, regulates neutrophil transmigration. J Biol Chem (2002) 1.63
Retracted Activation of phosphatidylinositol 3-kinase/Akt pathway by androgen through interaction of p85alpha, androgen receptor, and Src. J Biol Chem (2003) 1.63
Junctional adhesion molecule A interacts with Afadin and PDZ-GEF2 to activate Rap1A, regulate beta1 integrin levels, and enhance cell migration. Mol Biol Cell (2009) 1.61
Inflammatory bowel disease and the apical junctional complex. Ann N Y Acad Sci (2006) 1.59
Genome-wide signatures of convergent evolution in echolocating mammals. Nature (2013) 1.59
Ten years' experience with needle biopsy in the early diagnosis of sacroiliitis. Arthritis Rheum (2012) 1.59
Chemical vapour deposition growth of large single crystals of monolayer and bilayer graphene. Nat Commun (2013) 1.57
Neutrophil migration across tight junctions is mediated by adhesive interactions between epithelial coxsackie and adenovirus receptor and a junctional adhesion molecule-like protein on neutrophils. Mol Biol Cell (2005) 1.57
Leukocyte-epithelial interactions. Curr Opin Cell Biol (2003) 1.57
Annexin A1, formyl peptide receptor, and NOX1 orchestrate epithelial repair. J Clin Invest (2012) 1.57
Annexin I regulates SKCO-15 cell invasion by signaling through formyl peptide receptors. J Biol Chem (2006) 1.55
Pathobiology of neutrophil transepithelial migration: implications in mediating epithelial injury. Annu Rev Pathol (2007) 1.55
BMP4-mediated brown fat-like changes in white adipose tissue alter glucose and energy homeostasis. Proc Natl Acad Sci U S A (2013) 1.55
Excess mortality associated with influenza A and B virus in Hong Kong, 1998-2009. J Infect Dis (2012) 1.54
Effects of cellulose crystallinity, hemicellulose, and lignin on the enzymatic hydrolysis of Miscanthus sinensis to monosaccharides. Biosci Biotechnol Biochem (2008) 1.54
Endocytosis of the apical junctional complex: mechanisms and possible roles in regulation of epithelial barriers. Bioessays (2005) 1.52