Published in Brain Res on February 08, 2005
Voluntary exercise produces antidepressant and anxiolytic behavioral effects in mice. Brain Res (2008) 1.84
Long-term voluntary wheel running is rewarding and produces plasticity in the mesolimbic reward pathway. Behav Brain Res (2010) 1.59
The use of a running wheel to measure activity in rodents: relationship to energy balance, general activity, and reward. Neurosci Biobehav Rev (2012) 1.45
Biological mechanisms of physical activity in preventing cognitive decline. Cell Mol Neurobiol (2009) 1.20
A behavioral analysis of the impact of voluntary physical activity on hippocampus-dependent contextual conditioning. Hippocampus (2009) 1.12
Environmental and pharmacological modulations of cellular plasticity: role in the pathophysiology and treatment of depression. Neurobiol Dis (2012) 1.07
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Overlapping neurobiology of learned helplessness and conditioned defeat: implications for PTSD and mood disorders. Neuropharmacology (2011) 1.05
Exercise, stress resistance, and central serotonergic systems. Exerc Sport Sci Rev (2011) 1.05
Chronic voluntary wheel running facilitates corticosterone response habituation to repeated audiogenic stress exposure in male rats. Stress (2008) 1.02
Activation of 5-HT1A autoreceptors in the dorsal raphe nucleus reduces the behavioral consequences of social defeat. Psychoneuroendocrinology (2008) 1.00
Hypothalamic pituitary adrenal axis responses to low-intensity stressors are reduced after voluntary wheel running in rats. J Neuroendocrinol (2010) 1.00
Aggressive encounters alter the activation of serotonergic neurons and the expression of 5-HT1A mRNA in the hamster dorsal raphe nucleus. Neuroscience (2009) 0.99
Learned helplessness is independent of levels of brain-derived neurotrophic factor in the hippocampus. Neuroscience (2006) 0.97
A final common pathway for depression? Progress toward a general conceptual framework. Neurosci Biobehav Rev (2007) 0.93
Voluntary exercise offers anxiolytic potential and amplifies galanin gene expression in the locus coeruleus of the rat. Behav Brain Res (2012) 0.93
Chronic low dose ovine corticotropin releasing factor or urocortin II into the rostral dorsal raphe alters exploratory behavior and serotonergic gene expression in specific subregions of the dorsal raphe. Neuroscience (2007) 0.92
Anxiety-like behaviors produced by acute fluoxetine administration in male Fischer 344 rats are prevented by prior exercise. Psychopharmacology (Berl) (2008) 0.91
Exercise offers anxiolytic potential: a role for stress and brain noradrenergic-galaninergic mechanisms. Neurosci Biobehav Rev (2012) 0.91
The neurobiology of the stress-resistant brain. Stress (2011) 0.90
Lesions of the fasciculus retroflexus alter footshock-induced cFos expression in the mesopontine rostromedial tegmental area of rats. PLoS One (2013) 0.90
Exercise-associated changes in the corticosterone response to acute restraint stress: evidence for increased adrenal sensitivity and reduced corticosterone response duration. Neuropsychopharmacology (2013) 0.90
5-hydroxytryptamine 2C receptors in the dorsal striatum mediate stress-induced interference with negatively reinforced instrumental escape behavior. Neuroscience (2011) 0.89
Effects of physical exercise on central nervous system functions: a review of brain region specific adaptations. J Mol Psychiatry (2015) 0.89
Exercise-induced stress resistance is independent of exercise controllability and the medial prefrontal cortex. Eur J Neurosci (2012) 0.88
The protective effects of voluntary exercise against the behavioral consequences of uncontrollable stress persist despite an increase in anxiety following forced cessation of exercise. Behav Brain Res (2012) 0.87
Regulation of dorsal raphe nucleus function by serotonin autoreceptors: a behavioral perspective. J Chem Neuroanat (2011) 0.86
5-HT2C receptors in the basolateral amygdala and dorsal striatum are a novel target for the anxiolytic and antidepressant effects of exercise. PLoS One (2012) 0.86
Lesions of the basolateral amygdala reverse the long-lasting interference with shuttle box escape produced by uncontrollable stress. Behav Brain Res (2010) 0.86
Animal models of fear relapse. ILAR J (2014) 0.85
Risk-assessment and coping strategies segregate with divergent intrinsic aerobic capacity in rats. Neuropsychopharmacology (2010) 0.85
Voluntary wheel running produces resistance to inescapable stress-induced potentiation of morphine conditioned place preference. Behav Brain Res (2011) 0.85
Exercise is More Effective at Altering Gut Microbial Composition and Producing Stable Changes in Lean Mass in Juvenile versus Adult Male F344 Rats. PLoS One (2015) 0.85
Physical activity, but not environmental complexity, facilitates HPA axis response habituation to repeated audiogenic stress despite neurotrophin mRNA regulation in both conditions. Brain Res (2010) 0.83
Prior voluntary wheel running attenuates neuropathic pain. Pain (2016) 0.83
Galanin mediates features of neural and behavioral stress resilience afforded by exercise. Neuropharmacology (2014) 0.82
Defeat-induced activation of the ventral medial prefrontal cortex is necessary for resistance to conditioned defeat. Behav Brain Res (2013) 0.80
Acute reversible inactivation of the bed nucleus of stria terminalis induces antidepressant-like effect in the rat forced swimming test. Behav Brain Funct (2010) 0.80
Maintenance of dominance status is necessary for resistance to social defeat stress in Syrian hamsters. Behav Brain Res (2014) 0.78
Running Reduces Uncontrollable Stress-Evoked Serotonin and Potentiates Stress-Evoked Dopamine Concentrations in the Rat Dorsal Striatum. PLoS One (2015) 0.77
Dietary Prebiotics and Bioactive Milk Fractions Improve NREM Sleep, Enhance REM Sleep Rebound and Attenuate the Stress-Induced Decrease in Diurnal Temperature and Gut Microbial Alpha Diversity. Front Behav Neurosci (2017) 0.75
Brain activation patterns at exhaustion in rats that differ in inherent exercise capacity. PLoS One (2012) 0.75
Sex-dependent and independent effects of long-term voluntary wheel running on Bdnf mRNA and protein expression. Physiol Behav (2016) 0.75
Position statement. Part one: Immune function and exercise. Exerc Immunol Rev (2011) 3.69
Minocycline attenuates mechanical allodynia and proinflammatory cytokine expression in rat models of pain facilitation. Pain (2005) 3.34
The "toll" of opioid-induced glial activation: improving the clinical efficacy of opioids by targeting glia. Trends Pharmacol Sci (2009) 3.06
Microglia serve as a neuroimmune substrate for stress-induced potentiation of CNS pro-inflammatory cytokine responses. Brain Behav Immun (2006) 2.89
Spinal glia and proinflammatory cytokines mediate mirror-image neuropathic pain in rats. J Neurosci (2003) 2.87
Beyond neurons: evidence that immune and glial cells contribute to pathological pain states. Physiol Rev (2002) 2.75
Glia: a novel drug discovery target for clinical pain. Nat Rev Drug Discov (2003) 2.71
Non-stereoselective reversal of neuropathic pain by naloxone and naltrexone: involvement of toll-like receptor 4 (TLR4). Eur J Neurosci (2008) 2.65
Opioid-induced glial activation: mechanisms of activation and implications for opioid analgesia, dependence, and reward. ScientificWorldJournal (2007) 2.43
Peripheral infection and aging interact to impair hippocampal memory consolidation. Neurobiol Aging (2006) 2.37
"Brain-specific" nutrients: a memory cure? Nutrition (2003) 2.29
Evidence that opioids may have toll-like receptor 4 and MD-2 effects. Brain Behav Immun (2009) 2.19
A role for proinflammatory cytokines and fractalkine in analgesia, tolerance, and subsequent pain facilitation induced by chronic intrathecal morphine. J Neurosci (2004) 2.14
Previous experience with behavioral control over stress blocks the behavioral and dorsal raphe nucleus activating effects of later uncontrollable stress: role of the ventral medial prefrontal cortex. J Neurosci (2006) 2.07
mRNA up-regulation of MHC II and pivotal pro-inflammatory genes in normal brain aging. Neurobiol Aging (2006) 2.06
Norman Cousins Lecture. Glia as the "bad guys": implications for improving clinical pain control and the clinical utility of opioids. Brain Behav Immun (2006) 2.00
Intracisternal interleukin-1 receptor antagonist prevents postoperative cognitive decline and neuroinflammatory response in aged rats. J Neurosci (2012) 1.93
Proinflammatory cytokines oppose opioid-induced acute and chronic analgesia. Brain Behav Immun (2008) 1.92
Freewheel running prevents learned helplessness/behavioral depression: role of dorsal raphe serotonergic neurons. J Neurosci (2003) 1.91
The effects of 40 hours of total sleep deprivation on inflammatory markers in healthy young adults. Brain Behav Immun (2007) 1.91
Glia: novel counter-regulators of opioid analgesia. Trends Neurosci (2005) 1.86
Glial proinflammatory cytokines mediate exaggerated pain states: implications for clinical pain. Adv Exp Med Biol (2003) 1.84
Releasing signals, secretory pathways, and immune function of endogenous extracellular heat shock protein 72. J Leukoc Biol (2005) 1.83
Time course of hippocampal IL-1 beta and memory consolidation impairments in aging rats following peripheral infection. Brain Behav Immun (2008) 1.82
Prior stressor exposure sensitizes LPS-induced cytokine production. Brain Behav Immun (2002) 1.82
Glial activation and pathological pain. Neurochem Int (2004) 1.80
Controlling pathological pain by adenovirally driven spinal production of the anti-inflammatory cytokine, interleukin-10. Eur J Neurosci (2005) 1.73
Intrathecal interleukin-10 gene therapy attenuates paclitaxel-induced mechanical allodynia and proinflammatory cytokine expression in dorsal root ganglia in rats. Brain Behav Immun (2006) 1.67
Controlling neuropathic pain by adeno-associated virus driven production of the anti-inflammatory cytokine, interleukin-10. Mol Pain (2005) 1.66
Exploring the neuroimmunopharmacology of opioids: an integrative review of mechanisms of central immune signaling and their implications for opioid analgesia. Pharmacol Rev (2011) 1.66
Repeated intrathecal injections of plasmid DNA encoding interleukin-10 produce prolonged reversal of neuropathic pain. Pain (2006) 1.66
"Listening" and "talking" to neurons: implications of immune activation for pain control and increasing the efficacy of opioids. Brain Res Rev (2007) 1.62
Rapid isolation of highly enriched and quiescent microglia from adult rat hippocampus: immunophenotypic and functional characteristics. J Neurosci Methods (2005) 1.61
Long-term voluntary wheel running is rewarding and produces plasticity in the mesolimbic reward pathway. Behav Brain Res (2010) 1.59
Reduction of opioid withdrawal and potentiation of acute opioid analgesia by systemic AV411 (ibudilast). Brain Behav Immun (2008) 1.58
Memory for context is impaired by a post context exposure injection of interleukin-1 beta into dorsal hippocampus. Behav Brain Res (2002) 1.58
Prior exposure to glucocorticoids sensitizes the neuroinflammatory and peripheral inflammatory responses to E. coli lipopolysaccharide. Brain Behav Immun (2009) 1.58
5-hydroxytryptamine 2C receptors in the basolateral amygdala are involved in the expression of anxiety after uncontrollable traumatic stress. Biol Psychiatry (2009) 1.55
Corticotropin releasing hormone type 2 receptors in the dorsal raphe nucleus mediate the behavioral consequences of uncontrollable stress. J Neurosci (2003) 1.53
Neonatal infection induces memory impairments following an immune challenge in adulthood. Behav Neurosci (2005) 1.53
Differential expression of 5HT-1A, alpha 1b adrenergic, CRF-R1, and CRF-R2 receptor mRNA in serotonergic, gamma-aminobutyric acidergic, and catecholaminergic cells of the rat dorsal raphe nucleus. J Comp Neurol (2004) 1.52
Stress-induced extracellular Hsp72 is a functionally significant danger signal to the immune system. Cell Stress Chaperones (2003) 1.47
Chemical lesion of the bed nucleus of the stria terminalis blocks the behavioral consequences of uncontrollable stress. Behav Neurosci (2004) 1.44
Peripheral and central proinflammatory cytokine response to a severe acute stressor. Brain Res (2003) 1.42
Neonatal infection-induced memory impairment after lipopolysaccharide in adulthood is prevented via caspase-1 inhibition. J Neurosci (2005) 1.41
Sustained hippocampal IL-1beta overexpression impairs contextual and spatial memory in transgenic mice. Brain Behav Immun (2009) 1.36
Spinal gap junctions: potential involvement in pain facilitation. J Pain (2004) 1.36
The role of prior stressor controllability and the dorsal raphé nucleus in sucrose preference and social exploration. Behav Brain Res (2008) 1.36
Minocycline suppresses morphine-induced respiratory depression, suppresses morphine-induced reward, and enhances systemic morphine-induced analgesia. Brain Behav Immun (2008) 1.34
Exercise, learned helplessness, and the stress-resistant brain. Neuromolecular Med (2008) 1.33
Further characterization of high mobility group box 1 (HMGB1) as a proinflammatory cytokine: central nervous system effects. Cytokine (2003) 1.30
Central proinflammatory cytokines and pain enhancement. Neurosignals (2005) 1.30
Effects of prior stress on LPS-induced cytokine and sickness responses. Am J Physiol Regul Integr Comp Physiol (2002) 1.26
A behavioural characterization of neonatal infection-facilitated memory impairment in adult rats. Behav Brain Res (2006) 1.25
The cortical innate immune response increases local neuronal excitability leading to seizures. Brain (2009) 1.25
The role of corticotropin-releasing hormone in the dorsal raphe nucleus in mediating the behavioral consequences of uncontrollable stress. J Neurosci (2002) 1.24
Glucocorticoids mediate stress-induced priming of microglial pro-inflammatory responses. Brain Behav Immun (2011) 1.23
A method for measuring multiple cytokines from small samples. Brain Behav Immun (2004) 1.23
Neuroplasticity of dopamine circuits after exercise: implications for central fatigue. Neuromolecular Med (2008) 1.23
Selective activation of dorsal raphe nucleus-projecting neurons in the ventral medial prefrontal cortex by controllable stress. Eur J Neurosci (2009) 1.22
BDNF mRNA expression in rat hippocampus following contextual learning is blocked by intrahippocampal IL-1beta administration. J Neuroimmunol (2004) 1.19
Early-life infection leads to altered BDNF and IL-1beta mRNA expression in rat hippocampus following learning in adulthood. Brain Behav Immun (2007) 1.19
Little exercise, big effects: reversing aging and infection-induced memory deficits, and underlying processes. J Neurosci (2011) 1.19
Involvement of spinal cord nuclear factor kappaB activation in rat models of proinflammatory cytokine-mediated pain facilitation. Eur J Neurosci (2005) 1.19
Pain intensity and duration can be enhanced by prior challenge: initial evidence suggestive of a role of microglial priming. J Pain (2010) 1.19
The 1- to 2-Hz oscillations in muscle force are exacerbated by stress, especially in older adults. J Appl Physiol (1985) (2004) 1.18
Acute predator stress impairs the consolidation and retrieval of hippocampus-dependent memory in male and female rats. Learn Mem (2008) 1.18
Intrathecal polymer-based interleukin-10 gene delivery for neuropathic pain. Neuron Glia Biol (2006) 1.18
Enduring consequences of early-life infection on glial and neural cell genesis within cognitive regions of the brain. Brain Behav Immun (2009) 1.17
Medial prefrontal cortical activation modulates the impact of controllable and uncontrollable stressor exposure on a social exploration test of anxiety in the rat. Stress (2009) 1.17
Wheel running alters serotonin (5-HT) transporter, 5-HT1A, 5-HT1B, and alpha 1b-adrenergic receptor mRNA in the rat raphe nuclei. Biol Psychiatry (2005) 1.16
IL-1RA blocks E. coli-induced suppression of Arc and long-term memory in aged F344xBN F1 rats. Brain Behav Immun (2009) 1.15
Prior stressor exposure primes the HPA axis. Psychoneuroendocrinology (2002) 1.14
HIV-1 gp120 stimulates proinflammatory cytokine-mediated pain facilitation via activation of nitric oxide synthase-I (nNOS). Pain (2004) 1.13
Therapeutic effects of exercise: wheel running reverses stress-induced interference with shuttle box escape. Behav Neurosci (2007) 1.13
Aging sensitizes rapidly isolated hippocampal microglia to LPS ex vivo. J Neuroimmunol (2010) 1.12
A behavioral analysis of the impact of voluntary physical activity on hippocampus-dependent contextual conditioning. Hippocampus (2009) 1.12
Emotion-induced amnesia in rats: working memory-specific impairment, corticosterone-memory correlation, and fear versus arousal effects on memory. Learn Mem (2003) 1.11
Peri-sciatic proinflammatory cytokines, reactive oxygen species, and complement induce mirror-image neuropathic pain in rats. Pain (2004) 1.11
Synaptic correlates of increased cognitive vulnerability with aging: peripheral immune challenge and aging interact to disrupt theta-burst late-phase long-term potentiation in hippocampal area CA1. J Neurosci (2010) 1.11
Acute episodes of predator exposure in conjunction with chronic social instability as an animal model of post-traumatic stress disorder. Stress (2008) 1.10
Stressor controllability modulates stress-induced dopamine and serotonin efflux and morphine-induced serotonin efflux in the medial prefrontal cortex. Neuropsychopharmacology (2003) 1.09
Memory impairments in healthy aging: Role of aging-induced microglial sensitization. Aging Dis (2010) 1.09
The sensory insular cortex mediates the stress-buffering effects of safety signals but not behavioral control. J Neurosci (2008) 1.09
Safety signals mitigate the consequences of uncontrollable stress via a circuit involving the sensory insular cortex and bed nucleus of the stria terminalis. Biol Psychiatry (2011) 1.07
Influence of age and physical activity on the primary in vivo antibody and T cell-mediated responses in men. J Appl Physiol (1985) (2004) 1.07
Differential effects of neonatal handling on early life infection-induced alterations in cognition in adulthood. Brain Behav Immun (2006) 1.07
The glial activation inhibitor AV411 reduces morphine-induced nucleus accumbens dopamine release. Brain Behav Immun (2009) 1.07
Complement activation in a model of chronic fatigue syndrome. J Allergy Clin Immunol (2003) 1.05
Inescapable shock activates serotonergic neurons in all raphe nuclei of rat. Behav Brain Res (2004) 1.05
Exercise, stress resistance, and central serotonergic systems. Exerc Sport Sci Rev (2011) 1.05
Characterization of the sickness response in young and aging rats following E. coli infection. Brain Behav Immun (2009) 1.04