Published in Science on June 03, 2005
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Human LilrB2 is a β-amyloid receptor and its murine homolog PirB regulates synaptic plasticity in an Alzheimer's model. Science (2013) 3.59
Gabapentin receptor alpha2delta-1 is a neuronal thrombospondin receptor responsible for excitatory CNS synaptogenesis. Cell (2009) 3.46
Engineered SIRPα variants as immunotherapeutic adjuvants to anticancer antibodies. Science (2013) 3.25
How a single T cell receptor recognizes both self and foreign MHC. Cell (2007) 3.20
Structure of MERS-CoV spike receptor-binding domain complexed with human receptor DPP4. Cell Res (2013) 3.20
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Structure of the quaternary complex of interleukin-2 with its alpha, beta, and gammac receptors. Science (2005) 2.64
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Signaling conformations of the tall cytokine receptor gp130 when in complex with IL-6 and IL-6 receptor. Nat Struct Mol Biol (2005) 2.12
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Exploiting a natural conformational switch to engineer an interleukin-2 'superkine'. Nature (2012) 2.08
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A TNF receptor family member, TROY, is a coreceptor with Nogo receptor in mediating the inhibitory activity of myelin inhibitors. Neuron (2005) 2.03
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Small molecule-induced allosteric activation of the Vibrio cholerae RTX cysteine protease domain. Science (2008) 1.67
Deconstructing the form and function of the TCR/CD3 complex. Immunity (2006) 1.64
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Structural basis of receptor sharing by interleukin 17 cytokines. Nat Immunol (2009) 1.60
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Crystal structure of human RANKL complexed with its decoy receptor osteoprotegerin. J Immunol (2012) 1.50
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Cytokine therapy reverses NK cell anergy in MHC-deficient tumors. J Clin Invest (2014) 1.45
Structural and functional insights into the malaria parasite moving junction complex. PLoS Pathog (2012) 1.44
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The V alpha 14 NKT cell TCR exhibits high-affinity binding to a glycolipid/CD1d complex. J Immunol (2002) 1.38
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Mechanistic and structural insights into the proteolytic activation of Vibrio cholerae MARTX toxin. Nat Chem Biol (2009) 1.36
Structural basis of semaphorin-plexin recognition and viral mimicry from Sema7A and A39R complexes with PlexinC1. Cell (2010) 1.35
Structure of a human A-type potassium channel interacting protein DPPX, a member of the dipeptidyl aminopeptidase family. J Mol Biol (2004) 1.34
An autonomous CDR3delta is sufficient for recognition of the nonclassical MHC class I molecules T10 and T22 by gammadelta T cells. Nat Immunol (2008) 1.33
Genetic and neutralization sensitivity of diverse HIV-1 env clones from chronically infected patients in China. J Biol Chem (2011) 1.33
Structural insights into the assembly and activation of IL-1β with its receptors. Nat Immunol (2010) 1.32
Structural insight into pre-B cell receptor function. Science (2007) 1.29
Evidence for a functional sidedness to the alphabetaTCR. Proc Natl Acad Sci U S A (2010) 1.24
Biochemical and structural characterization of the paralogous benzoate CoA ligases from Burkholderia xenovorans LB400: defining the entry point into the novel benzoate oxidation (box) pathway. J Mol Biol (2007) 1.20
Simplified, enhanced protein purification using an inducible, autoprocessing enzyme tag. PLoS One (2009) 1.19
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Structural elucidation of the m157 mouse cytomegalovirus ligand for Ly49 natural killer cell receptors. Proc Natl Acad Sci U S A (2007) 1.17
Structural organization of a full-length gp130/LIF-R cytokine receptor transmembrane complex. Mol Cell (2008) 1.17
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Structural insights into the interaction of IL-33 with its receptors. Proc Natl Acad Sci U S A (2013) 1.09
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Solution mapping of T cell receptor docking footprints on peptide-MHC. Proc Natl Acad Sci U S A (2007) 1.06
Secreted semaphorins from degenerating larval ORN axons direct adult projection neuron dendrite targeting. Neuron (2011) 1.06
Shared cytokine signaling receptors: structural insights from the gp130 system. Adv Protein Chem (2004) 1.06
Structure of the activating IL-1 receptor signaling complex. Nat Struct Mol Biol (2012) 1.06
Molecular mechanisms for viral mimicry of a human cytokine: activation of gp130 by HHV-8 interleukin-6. J Mol Biol (2004) 1.05
Molecular and structural insight into proNGF engagement of p75NTR and sortilin. J Mol Biol (2009) 1.05
The structure of interleukin-23 reveals the molecular basis of p40 subunit sharing with interleukin-12. J Mol Biol (2008) 1.04
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Structural and functional characterization of SporoSAG: a SAG2-related surface antigen from Toxoplasma gondii. J Biol Chem (2010) 0.99
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