Published in Trends Microbiol on July 01, 2004
Exosome function: from tumor immunology to pathogen biology. Traffic (2008) 4.50
Exosomes and HIV Gag bud from endosome-like domains of the T cell plasma membrane. J Cell Biol (2006) 4.33
Alzheimer's disease beta-amyloid peptides are released in association with exosomes. Proc Natl Acad Sci U S A (2006) 3.98
Proteomic and biochemical analysis of purified human immunodeficiency virus type 1 produced from infected monocyte-derived macrophages. J Virol (2006) 3.59
Discovery of insect and human dengue virus host factors. Nature (2009) 3.49
Itinerant exosomes: emerging roles in cell and tissue polarity. Trends Cell Biol (2008) 2.93
HIV-1 buds predominantly at the plasma membrane of primary human macrophages. PLoS Pathog (2007) 2.44
Proteomic and immunologic analyses of brain tumor exosomes. FASEB J (2008) 2.11
Exosomal transfer of proteins and RNAs at synapses in the nervous system. Biol Direct (2007) 1.93
The fatal fungal outbreak on Vancouver Island is characterized by enhanced intracellular parasitism driven by mitochondrial regulation. Proc Natl Acad Sci U S A (2009) 1.84
Dynamic fluorescent imaging of human immunodeficiency virus type 1 gag in live cells by biarsenical labeling. J Virol (2005) 1.65
Lung cancer secreted microvesicles: underappreciated modulators of microenvironment in expanding tumors. Int J Cancer (2009) 1.64
Retrovirus infection strongly enhances scrapie infectivity release in cell culture. EMBO J (2006) 1.53
Herpes simplex virus type 1 cytoplasmic envelopment requires functional Vps4. J Virol (2007) 1.45
Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages. J Immunol (2012) 1.42
Syntenin-1 is a new component of tetraspanin-enriched microdomains: mechanisms and consequences of the interaction of syntenin-1 with CD63. Mol Cell Biol (2006) 1.32
Hepatitis B virus maturation is sensitive to functional inhibition of ESCRT-III, Vps4, and gamma 2-adaptin. J Virol (2007) 1.32
Detachment of breast tumor cells induces rapid secretion of exosomes which subsequently mediate cellular adhesion and spreading. PLoS One (2011) 1.32
Human herpesvirus-6 induces MVB formation, and virus egress occurs by an exosomal release pathway. Traffic (2008) 1.31
The cell biology of HIV-1 and other retroviruses. Retrovirology (2006) 1.21
Extracellular vesicles and their convergence with viral pathways. Adv Virol (2012) 1.18
HIV-1 Assembly at the Plasma Membrane: Gag Trafficking and Localization. Future Virol (2009) 1.11
Cells infected with herpes simplex virus 1 export to uninfected cells exosomes containing STING, viral mRNAs, and microRNAs. Proc Natl Acad Sci U S A (2014) 1.09
Medulloblastoma exosome proteomics yield functional roles for extracellular vesicles. PLoS One (2012) 1.08
Curcumin reverses breast tumor exosomes mediated immune suppression of NK cell tumor cytotoxicity. Biochim Biophys Acta (2007) 1.05
Vacuolar transport in tobacco leaf epidermis cells involves a single route for soluble cargo and multiple routes for membrane cargo. Plant Cell (2011) 1.02
Microvesicles/exosomes as potential novel biomarkers of metabolic diseases. Diabetes Metab Syndr Obes (2012) 1.01
COP9-associated CSN5 regulates exosomal protein deubiquitination and sorting. Am J Pathol (2009) 1.01
Endosomal trafficking of HIV-1 gag and genomic RNAs regulates viral egress. J Biol Chem (2009) 1.01
Identification of host proteins associated with retroviral vector particles by proteomic analysis of highly purified vector preparations. J Virol (2007) 1.01
A critical role for CD63 in HIV replication and infection of macrophages and cell lines. Virology (2008) 0.95
Human Cytomegalovirus UL135 and UL136 Genes Are Required for Postentry Tropism in Endothelial Cells. J Virol (2015) 0.95
Ubiquitination of the prototype foamy virus envelope glycoprotein leader peptide regulates subviral particle release. J Virol (2005) 0.94
Stability of membranous nanostructures: a possible key mechanism in cancer progression. Int J Nanomedicine (2012) 0.92
Paracrine diffusion of PrP(C) and propagation of prion infectivity by plasma membrane-derived microvesicles. PLoS One (2009) 0.91
Plasmacytoid dendritic cells sequester high prion titres at early stages of prion infection. PLoS Pathog (2012) 0.89
Microparticles mediated cross-talk between tumoral and endothelial cells promote the constitution of a pro-metastatic vascular niche through Arf6 up regulation. Cancer Microenviron (2014) 0.87
Cellular microvesicle pathways can be targeted to transfer genetic information between non-immune cells. PLoS One (2009) 0.86
CD81 and CD9 work independently as extracellular components upon fusion of sperm and oocyte. Biol Open (2012) 0.86
Exosomes released from breast cancer carcinomas stimulate cell movement. PLoS One (2015) 0.86
HIV-1 is budded from CD4+ T lymphocytes independently of exosomes. Virol J (2010) 0.85
Neurokinin 1 receptor mediates membrane blebbing and sheer stress-induced microparticle formation in HEK293 cells. PLoS One (2012) 0.82
pH-Dependent lytic peptides discovered by phage display. Biochemistry (2006) 0.82
Extracellular vesicles and viruses: Are they close relatives? Proc Natl Acad Sci U S A (2016) 0.82
The mixed lineage kinase-3 inhibitor URMC-099 improves therapeutic outcomes for long-acting antiretroviral therapy. Nanomedicine (2015) 0.81
Disease Mechanisms in ALS: Misfolded SOD1 Transferred Through Exosome-Dependent and Exosome-Independent Pathways. Cell Mol Neurobiol (2016) 0.80
Exosomes in Human Immunodeficiency Virus Type I Pathogenesis: Threat or Opportunity? Adv Virol (2016) 0.80
Cellular basis of Alzheimer's disease. Ann Indian Acad Neurol (2010) 0.77
Class II transactivator (CIITA) enhances cytoplasmic processing of HIV-1 Pr55Gag. PLoS One (2010) 0.77
Budding of Tiger Frog Virus (an Iridovirus) from HepG2 Cells via Three Ways Recruits the ESCRT Pathway. Sci Rep (2016) 0.75
Influence of cellular trafficking pathway on bluetongue virus infection in ovine cells. Viruses (2015) 0.75
Mechanisms of HIV Neuropathogenesis: Role of Cellular Communication Systems. Curr HIV Res (2016) 0.75
On the general theory of the origins of retroviruses. Theor Biol Med Model (2010) 0.75
Isolation and characterization of exosomes from cell culture supernatants and biological fluids. Curr Protoc Cell Biol (2006) 13.29
Exosomes--vesicular carriers for intercellular communication. Curr Opin Cell Biol (2009) 6.96
Exosomal-like vesicles are present in human blood plasma. Int Immunol (2005) 6.04
Exosomes: a common pathway for a specialized function. J Biochem (2006) 5.79
Exosomes: endosomal-derived vesicles shipping extracellular messages. Curr Opin Cell Biol (2004) 5.71
Rab27a and Rab27b control different steps of the exosome secretion pathway. Nat Cell Biol (2009) 5.44
NOX2 controls phagosomal pH to regulate antigen processing during crosspresentation by dendritic cells. Cell (2006) 5.35
Cells release prions in association with exosomes. Proc Natl Acad Sci U S A (2004) 5.17
Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3). Cell (2003) 4.94
Infectious HIV-1 assembles in late endosomes in primary macrophages. J Cell Biol (2003) 4.68
The biogenesis and functions of exosomes. Traffic (2002) 4.49
Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles. Annu Rev Cell Dev Biol (2014) 3.97
Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn's disease. J Exp Med (2009) 3.58
Cells respond to mechanical stress by rapid disassembly of caveolae. Cell (2011) 3.55
Shiga toxin induces tubular membrane invaginations for its uptake into cells. Nature (2007) 3.51
Exosome secretion: molecular mechanisms and roles in immune responses. Traffic (2011) 3.36
TCR activation of human T cells induces the production of exosomes bearing the TCR/CD3/zeta complex. J Immunol (2002) 3.28
A novel dendritic cell subset involved in tumor immunosurveillance. Nat Med (2006) 3.21
As we wait: coping with an imperfect nomenclature for extracellular vesicles. J Extracell Vesicles (2013) 3.01
Regulation of dendritic cell migration by CD74, the MHC class II-associated invariant chain. Science (2008) 2.88
Rab38 and Rab32 control post-Golgi trafficking of melanogenic enzymes. J Cell Biol (2006) 2.79
The Silver locus product Pmel17/gp100/Silv/ME20: controversial in name and in function. Pigment Cell Res (2005) 2.71
Rab27a regulates phagosomal pH and NADPH oxidase recruitment to dendritic cell phagosomes. Nat Cell Biol (2007) 2.69
In macrophages, HIV-1 assembles into an intracellular plasma membrane domain containing the tetraspanins CD81, CD9, and CD53. J Cell Biol (2007) 2.68
Inhibition of retrograde transport protects mice from lethal ricin challenge. Cell (2010) 2.67
The on-off story of protein palmitoylation. Trends Cell Biol (2003) 2.58
Functions of adaptor protein (AP)-3 and AP-1 in tyrosinase sorting from endosomes to melanosomes. Mol Biol Cell (2005) 2.56
Regulation of retromer recruitment to endosomes by sequential action of Rab5 and Rab7. J Cell Biol (2008) 2.56
HIV-1 trafficking to the dendritic cell-T-cell infectious synapse uses a pathway of tetraspanin sorting to the immunological synapse. Traffic (2005) 2.47
Multiphoton-FLIM quantification of the EGFP-mRFP1 FRET pair for localization of membrane receptor-kinase interactions. Biophys J (2004) 2.37
BLOC-1 interacts with BLOC-2 and the AP-3 complex to facilitate protein trafficking on endosomes. Mol Biol Cell (2006) 2.37
ICAM-1 on exosomes from mature dendritic cells is critical for efficient naive T-cell priming. Blood (2005) 2.34
A lumenal domain-dependent pathway for sorting to intralumenal vesicles of multivesicular endosomes involved in organelle morphogenesis. Dev Cell (2006) 2.29
Secretory cytotoxic granule maturation and exocytosis require the effector protein hMunc13-4. Nat Immunol (2007) 2.28
Simian immunodeficiency virus envelope glycoprotein counteracts tetherin/BST-2/CD317 by intracellular sequestration. Proc Natl Acad Sci U S A (2009) 2.21
Cell-specific ATP7A transport sustains copper-dependent tyrosinase activity in melanosomes. Nature (2008) 2.15
Single-cell analysis of population context advances RNAi screening at multiple levels. Mol Syst Biol (2012) 2.13
Proprotein convertase cleavage liberates a fibrillogenic fragment of a resident glycoprotein to initiate melanosome biogenesis. J Cell Biol (2003) 2.12
BLOC-1 is required for cargo-specific sorting from vacuolar early endosomes toward lysosome-related organelles. Mol Biol Cell (2006) 2.11
Multifocal structure of the T cell - dendritic cell synapse. Eur J Immunol (2005) 2.09
Diverse subpopulations of vesicles secreted by different intracellular mechanisms are present in exosome preparations obtained by differential ultracentrifugation. J Extracell Vesicles (2012) 2.06
ARF6 controls post-endocytic recycling through its downstream exocyst complex effector. J Cell Biol (2003) 2.02
AP-1 and KIF13A coordinate endosomal sorting and positioning during melanosome biogenesis. J Cell Biol (2009) 1.99
MHC II in dendritic cells is targeted to lysosomes or T cell-induced exosomes via distinct multivesicular body pathways. Traffic (2009) 1.98
Analysis of ESCRT functions in exosome biogenesis, composition and secretion highlights the heterogeneity of extracellular vesicles. J Cell Sci (2013) 1.98
A dual mechanism controlling the localization and function of exocytic v-SNAREs. Proc Natl Acad Sci U S A (2003) 1.86
Exosomes as potent cell-free peptide-based vaccine. I. Dendritic cell-derived exosomes transfer functional MHC class I/peptide complexes to dendritic cells. J Immunol (2004) 1.86
The tetraspanin CD63 regulates ESCRT-independent and -dependent endosomal sorting during melanogenesis. Dev Cell (2011) 1.82
The retromer complex and clathrin define an early endosomal retrograde exit site. J Cell Sci (2007) 1.80
Involvement of caspase-cleaved and intact adaptor protein 1 complex in endosomal remodeling in maturing dendritic cells. Nat Immunol (2005) 1.76
The cell biology of receptor-mediated virus entry. J Cell Biol (2011) 1.75
TI-VAMP/VAMP7 is required for optimal phagocytosis of opsonised particles in macrophages. EMBO J (2004) 1.71
Localization of HCMV UL33 and US27 in endocytic compartments and viral membranes. Traffic (2002) 1.65
Diaphanous-related formins are required for invadopodia formation and invasion of breast tumor cells. Cancer Res (2009) 1.63
T84-intestinal epithelial exosomes bear MHC class II/peptide complexes potentiating antigen presentation by dendritic cells. Gastroenterology (2007) 1.60
Lysosome-related organelles: unusual compartments become mainstream. Curr Opin Cell Biol (2013) 1.59
Retrovirus infection strongly enhances scrapie infectivity release in cell culture. EMBO J (2006) 1.53
ARF6 Interacts with JIP4 to control a motor switch mechanism regulating endosome traffic in cytokinesis. Curr Biol (2009) 1.52
Inositol pyrophosphate mediated pyrophosphorylation of AP3B1 regulates HIV-1 Gag release. Proc Natl Acad Sci U S A (2009) 1.42
Synchronization of secretory protein traffic in populations of cells. Nat Methods (2012) 1.41
Exosomes bearing HLA-DR1 molecules need dendritic cells to efficiently stimulate specific T cells. Int Immunol (2002) 1.41
Rab27A and its effector MyRIP link secretory granules to F-actin and control their motion towards release sites. J Cell Biol (2003) 1.40
A conserved dileucine motif mediates clathrin and AP-2-dependent endocytosis of the HIV-1 envelope protein. Mol Biol Cell (2006) 1.38
Dual loss of ER export and endocytic signals with altered melanosome morphology in the silver mutation of Pmel17. Mol Biol Cell (2006) 1.37
Mouse neuroblastoma cells release prion infectivity associated with exosomal vesicles. Biol Cell (2008) 1.33
HIV interaction with endosomes in macrophages and dendritic cells. Blood Cells Mol Dis (2005) 1.32
Analysis of articulation between clathrin and retromer in retrograde sorting on early endosomes. Traffic (2009) 1.30
N-terminal domains elicit formation of functional Pmel17 amyloid fibrils. J Biol Chem (2009) 1.28
Endocytosis of the viral chemokine receptor US28 does not require beta-arrestins but is dependent on the clathrin-mediated pathway. Traffic (2003) 1.26
Agonist-induced endocytosis of CC chemokine receptor 5 is clathrin dependent. Mol Biol Cell (2004) 1.24
Exosomes: a bubble ride for prions? Traffic (2005) 1.24
Rab27b regulates mast cell granule dynamics and secretion. Traffic (2007) 1.22
Birbeck granules are subdomains of endosomal recycling compartment in human epidermal Langerhans cells, which form where Langerin accumulates. Mol Biol Cell (2002) 1.21
Regulation of endocytic clathrin dynamics by cargo ubiquitination. Dev Cell (2012) 1.19
Human immunodeficiency virus-1 Nef expression induces intracellular accumulation of multivesicular bodies and major histocompatibility complex class II complexes: potential role of phosphatidylinositol 3-kinase. Mol Biol Cell (2003) 1.18
The ESCRT-0 component HRS is required for HIV-1 Vpu-mediated BST-2/tetherin down-regulation. PLoS Pathog (2011) 1.18
The actin-based motor protein myosin II regulates MHC class II trafficking and BCR-driven antigen presentation. J Cell Biol (2007) 1.17
Bluetongue virus entry into cells. J Virol (2007) 1.17
Premelanosome amyloid-like fibrils are composed of only golgi-processed forms of Pmel17 that have been proteolytically processed in endosomes. J Biol Chem (2007) 1.17
Myosin 1b promotes the formation of post-Golgi carriers by regulating actin assembly and membrane remodelling at the trans-Golgi network. Nat Cell Biol (2011) 1.16
Dynamics of major histocompatibility complex class II compartments during B cell receptor-mediated cell activation. J Exp Med (2002) 1.16
The ESCRT machinery is not required for human cytomegalovirus envelopment. Cell Microbiol (2007) 1.13
Myosin Ib modulates the morphology and the protein transport within multi-vesicular sorting endosomes. J Cell Sci (2005) 1.13
Prions and exosomes: from PrPc trafficking to PrPsc propagation. Blood Cells Mol Dis (2005) 1.12
Protein complexes containing CYFIP/Sra/PIR121 coordinate Arf1 and Rac1 signalling during clathrin-AP-1-coated carrier biogenesis at the TGN. Nat Cell Biol (2010) 1.11
Rab6-interacting protein 1 links Rab6 and Rab11 function. Traffic (2007) 1.11
Expression of the Longin domain of TI-VAMP impairs lysosomal secretion and epithelial cell migration. Biol Cell (2007) 1.11
Inhibition of nuclear import and cell-cycle progression by mutated forms of the dynamin-like GTPase MxB. Proc Natl Acad Sci U S A (2004) 1.11
NK1 receptor fused to beta-arrestin displays a single-component, high-affinity molecular phenotype. Mol Pharmacol (2002) 1.08
CD63 is not required for production of infectious human immunodeficiency virus type 1 in human macrophages. J Virol (2008) 1.07
The ocular albinism type 1 (OA1) G-protein-coupled receptor functions with MART-1 at early stages of melanogenesis to control melanosome identity and composition. Hum Mol Genet (2009) 1.06
Ang2/fat-free is a conserved subunit of the Golgi-associated retrograde protein complex. Mol Biol Cell (2010) 1.06
The role of ubiquitination in lysosomal trafficking of δ-opioid receptors. Traffic (2010) 1.05
ESCRT-I function is required for Tyrp1 transport from early endosomes to the melanosome limiting membrane. Traffic (2009) 1.05
BACE2 processes PMEL to form the melanosome amyloid matrix in pigment cells. Proc Natl Acad Sci U S A (2013) 1.04
The gene responsible for Dyggve-Melchior-Clausen syndrome encodes a novel peripheral membrane protein dynamically associated with the Golgi apparatus. Hum Mol Genet (2008) 1.03
The ERM proteins interact with the HOPS complex to regulate the maturation of endosomes. Mol Biol Cell (2010) 1.02
General strategy for decoration of enveloped viruses with functionally active lipid-modified cytokines. J Virol (2007) 1.01
A dual role for K63-linked ubiquitin chains in multivesicular body biogenesis and cargo sorting. Mol Biol Cell (2012) 1.00