Published in J Neurosci on October 05, 2005
Promoter-wide hypermethylation of the ribosomal RNA gene promoter in the suicide brain. PLoS One (2008) 2.40
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APE1/Ref-1 interacts with NPM1 within nucleoli and plays a role in the rRNA quality control process. Mol Cell Biol (2009) 1.58
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The earliest stage of cognitive impairment in transition from normal aging to Alzheimer disease is marked by prominent RNA oxidation in vulnerable neurons. J Neuropathol Exp Neurol (2012) 1.09
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The effects of aging vs. α7 nAChR subunit deficiency on the mouse brain transcriptome: aging beats the deficiency. Age (Dordr) (2010) 0.79
Role of Oxidative RNA Damage in Chronic-Degenerative Diseases. Oxid Med Cell Longev (2015) 0.79
An assay for RNA oxidation induced abasic sites using the Aldehyde Reactive Probe. Free Radic Res (2010) 0.79
Pathological Tau Promotes Neuronal Damage by Impairing Ribosomal Function and Decreasing Protein Synthesis. J Neurosci (2016) 0.79
Identification of Novel Tau Interactions with Endoplasmic Reticulum Proteins in Alzheimer's Disease Brain. J Alzheimers Dis (2015) 0.78
Insights into the regulation of neuronal viability by nucleophosmin/B23. Exp Biol Med (Maywood) (2015) 0.78
Battle against RNA oxidation: molecular mechanisms for reducing oxidized RNA to protect cells. Wiley Interdiscip Rev RNA (2013) 0.78
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Quantification of oxidized levels of specific RNA species using an aldehyde reactive probe. Anal Biochem (2011) 0.77
Limited effects of an eIF2αS51A allele on neurological impairments in the 5xFAD mouse model of Alzheimer's disease. Neural Plast (2015) 0.77
Altered machinery of protein synthesis is region- and stage-dependent and is associated with α-synuclein oligomers in Parkinson's disease. Acta Neuropathol Commun (2015) 0.77
Non-random distribution of methyl-CpG sites and non-CpG methylation in the human rDNA promoter identified by next generation bisulfite sequencing. Gene (2016) 0.76
RNA oxidation catalyzed by cytochrome c leads to its depurination and cross-linking, which may facilitate cytochrome c release from mitochondria. Free Radic Biol Med (2012) 0.76
Nuclear Tau and Its Potential Role in Alzheimer's Disease. Biomolecules (2016) 0.76
Sequestration of Ribosome during Protein Aggregate Formation: Contribution of ribosomal RNA. Sci Rep (2017) 0.75
Determining the Molecular Pathways Underlying the Protective Effect of Non-Steroidal Anti-Inflammatory Drugs for Alzheimer's Disease: A Bioinformatics Approach. Comput Struct Biotechnol J (2016) 0.75
Impaired APP activity and altered Tau splicing in embryonic stem cell-derived astrocytes obtained from an APPsw transgenic minipig. Dis Model Mech (2015) 0.75
Nucleolar PARP-1 Expression Is Decreased in Alzheimer's Disease: Consequences for Epigenetic Regulation of rDNA and Cognition. Neural Plast (2016) 0.75
Genes of susceptibility to early neurodegenerative changes in the rat retina and brain: analysis by means of congenic strains. BMC Genet (2016) 0.75
Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism. Nat Commun (2017) 0.75
A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts. Cell Stem Cell (2010) 7.94
The c-Myc target gene network. Semin Cancer Biol (2006) 5.98
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Vitamin C enhances the generation of mouse and human induced pluripotent stem cells. Cell Stem Cell (2009) 5.49
HIF-dependent antitumorigenic effect of antioxidants in vivo. Cancer Cell (2007) 4.81
MTDH activation by 8q22 genomic gain promotes chemoresistance and metastasis of poor-prognosis breast cancer. Cancer Cell (2009) 4.47
Neuropathology of nondemented aging: presumptive evidence for preclinical Alzheimer disease. Neurobiol Aging (2009) 4.36
Interferon antagonist proteins of influenza and vaccinia viruses are suppressors of RNA silencing. Proc Natl Acad Sci U S A (2004) 3.85
Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology. Am J Pathol (2002) 3.23
Cerebrovascular pathology and dementia in autopsied Honolulu-Asia Aging Study participants. Ann N Y Acad Sci (2002) 3.11
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TDP-43 in the ubiquitin pathology of frontotemporal dementia with VCP gene mutations. J Neuropathol Exp Neurol (2007) 2.97
Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54. Nat Genet (2010) 2.95
Genetic evidence supports demic diffusion of Han culture. Nature (2004) 2.92
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Alzheimer's neurofibrillary pathology and the spectrum of cognitive function: findings from the Nun Study. Ann Neurol (2002) 2.68
Fatty liver and the metabolic syndrome among Shanghai adults. J Gastroenterol Hepatol (2005) 2.67
Clinicopathologic correlations in a large Alzheimer disease center autopsy cohort: neuritic plaques and neurofibrillary tangles "do count" when staging disease severity. J Neuropathol Exp Neurol (2007) 2.65
Mechanism of induction and suppression of antiviral immunity directed by virus-derived small RNAs in Drosophila. Cell Host Microbe (2008) 2.48
Filamin is essential in actin cytoskeletal assembly mediated by p21-activated kinase 1. Nat Cell Biol (2002) 2.45
Modeling the association between 43 different clinical and pathological variables and the severity of cognitive impairment in a large autopsy cohort of elderly persons. Brain Pathol (2008) 2.44
Novel ubiquitin neuropathology in frontotemporal dementia with valosin-containing protein gene mutations. J Neuropathol Exp Neurol (2006) 2.43
Suppression of antiviral silencing by cucumber mosaic virus 2b protein in Arabidopsis is associated with drastically reduced accumulation of three classes of viral small interfering RNAs. Plant Cell (2007) 2.43
Chaperones increase association of tau protein with microtubules. Proc Natl Acad Sci U S A (2003) 2.32
Global surveillance of emerging Influenza virus genotypes by mass spectrometry. PLoS One (2007) 2.29
Association of olfactory dysfunction with incidental Lewy bodies. Mov Disord (2006) 2.26
Age and gender effects on human brain anatomy: a voxel-based morphometric study in healthy elderly. Neurobiol Aging (2006) 2.23
Controllable self-assembly of nanoparticles for specific delivery of multiple therapeutic molecules to cancer cells using RNA nanotechnology. Nano Lett (2005) 2.22
Prevalence of and risk factors for fatty liver in a general population of Shanghai, China. J Hepatol (2005) 2.21
Global regulation of nucleotide biosynthetic genes by c-Myc. PLoS One (2008) 2.12
Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part I: creatine kinase BB, glutamine synthase, and ubiquitin carboxy-terminal hydrolase L-1. Free Radic Biol Med (2002) 2.10
Lipid peroxidation in aging brain and Alzheimer's disease. Free Radic Biol Med (2002) 2.08
Redox proteomics identification of oxidatively modified hippocampal proteins in mild cognitive impairment: insights into the development of Alzheimer's disease. Neurobiol Dis (2006) 2.04
GGA proteins mediate the recycling pathway of memapsin 2 (BACE). J Biol Chem (2004) 1.99
Methodological Considerations in Studying Centenarians: Lessons Learned From the Georgia Centenarian Studies. Annu Rev Gerontol Geriatr (2007) 1.85
Isolation of a novel swine influenza virus from Oklahoma in 2011 which is distantly related to human influenza C viruses. PLoS Pathog (2013) 1.83
Cognitive impairment following high fat diet consumption is associated with brain inflammation. J Neuroimmunol (2009) 1.82
High-energy MnO2 nanowire/graphene and graphene asymmetric electrochemical capacitors. ACS Nano (2010) 1.81
Complexin cross-links prefusion SNAREs into a zigzag array. Nat Struct Mol Biol (2011) 1.81
Effects of high fat diet on Morris maze performance, oxidative stress, and inflammation in rats: contributions of maternal diet. Neurobiol Dis (2009) 1.80
Integrating multiple 'omics' analysis for microbial biology: application and methodologies. Microbiology (2009) 1.79
Rapid identification of emerging infectious agents using PCR and electrospray ionization mass spectrometry. Ann N Y Acad Sci (2007) 1.79
Graphene anchored with co(3)o(4) nanoparticles as anode of lithium ion batteries with enhanced reversible capacity and cyclic performance. ACS Nano (2010) 1.78
Characterization of a novel influenza virus in cattle and Swine: proposal for a new genus in the Orthomyxoviridae family. MBio (2014) 1.75
Generation of PPARγ mono-allelic knockout pigs via zinc-finger nucleases and nuclear transfer cloning. Cell Res (2011) 1.74
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Low sensitivity in clinical diagnoses of dementia with Lewy bodies. J Neurol (2009) 1.73
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Genotypic variation and mixtures of Lyme Borrelia in Ixodes ticks from North America and Europe. PLoS One (2010) 1.73
In vitro resistance to the human immunodeficiency virus type 1 maturation inhibitor PA-457 (Bevirimat). J Virol (2006) 1.70
Proteomic identification of nitrated proteins in Alzheimer's disease brain. J Neurochem (2003) 1.70
Budding of equine infectious anemia virus is insensitive to proteasome inhibitors. J Virol (2002) 1.67
EUS and survival in patients with pancreatic cancer: a population-based study. Gastrointest Endosc (2010) 1.66
Early life linguistic ability, late life cognitive function, and neuropathology: findings from the Nun Study. Neurobiol Aging (2005) 1.66
Lung cancer: performance of automated lung nodule detection applied to cancers missed in a CT screening program. Radiology (2002) 1.66
Brains with medial temporal lobe neurofibrillary tangles but no neuritic amyloid plaques are a diagnostic dilemma but may have pathogenetic aspects distinct from Alzheimer disease. J Neuropathol Exp Neurol (2009) 1.66
3D aperiodic hierarchical porous graphitic carbon material for high-rate electrochemical capacitive energy storage. Angew Chem Int Ed Engl (2008) 1.64
Computer-aided diagnosis in thoracic CT. Semin Ultrasound CT MR (2005) 1.63
Photoperiod- and thermo-sensitive genic male sterility in rice are caused by a point mutation in a novel noncoding RNA that produces a small RNA. Cell Res (2012) 1.63
Identification of miniature inverted-repeat transposable elements (MITEs) and biogenesis of their siRNAs in the Solanaceae: new functional implications for MITEs. Genome Res (2008) 1.63
Hepatitis B virus X protein sensitizes cells to starvation-induced autophagy via up-regulation of beclin 1 expression. Hepatology (2009) 1.62
Oxidative DNA damage in mild cognitive impairment and late-stage Alzheimer's disease. Nucleic Acids Res (2007) 1.62
Bacterial effector binding to ribosomal protein s3 subverts NF-kappaB function. PLoS Pathog (2009) 1.61
Increased levels of 4-hydroxynonenal and acrolein, neurotoxic markers of lipid peroxidation, in the brain in Mild Cognitive Impairment and early Alzheimer's disease. Neurobiol Aging (2005) 1.60
Crystal structure of the T315I mutant of AbI kinase. Chem Biol Drug Des (2007) 1.60
Digital image analysis of EUS images accurately differentiates pancreatic cancer from chronic pancreatitis and normal tissue. Gastrointest Endosc (2008) 1.59
Identification of nitrated proteins in Alzheimer's disease brain using a redox proteomics approach. Neurobiol Dis (2005) 1.58
Toll-like receptor-4 mediates neuronal apoptosis induced by amyloid beta-peptide and the membrane lipid peroxidation product 4-hydroxynonenal. Exp Neurol (2008) 1.58
3-O-(3',3'-dimethysuccinyl) betulinic acid inhibits maturation of the human immunodeficiency virus type 1 Gag precursor assembled in vitro. J Virol (2006) 1.58
RNA in brain disease: no longer just "the messenger in the middle". J Neuropathol Exp Neurol (2007) 1.57
Autophagy, proteasomes, lipofuscin, and oxidative stress in the aging brain. Int J Biochem Cell Biol (2004) 1.57
p21-Activated kinase 6 (PAK6) inhibits prostate cancer growth via phosphorylation of androgen receptor and tumorigenic E3 ligase murine double minute-2 (Mdm2). J Biol Chem (2012) 1.55
RNA silencing: a conserved antiviral immunity of plants and animals. Virus Res (2004) 1.54
Oxidative damage in mild cognitive impairment and early Alzheimer's disease. J Neurosci Res (2007) 1.54
Increased oxidative damage in nuclear and mitochondrial DNA in mild cognitive impairment. J Neurochem (2006) 1.52
Direct broad-range detection of alphaviruses in mosquito extracts. Virology (2007) 1.52
Internalized antibodies to the Abeta domain of APP reduce neuronal Abeta and protect against synaptic alterations. J Biol Chem (2007) 1.52
Redox proteomics identification of oxidized proteins in Alzheimer's disease hippocampus and cerebellum: an approach to understand pathological and biochemical alterations in AD. Neurobiol Aging (2005) 1.52
Oxidative modification and down-regulation of Pin1 in Alzheimer's disease hippocampus: A redox proteomics analysis. Neurobiol Aging (2005) 1.50
Functional inactivation of a transcriptional corepressor by a signaling kinase. Nat Struct Biol (2003) 1.50
Platelets generated from human embryonic stem cells are functional in vitro and in the microcirculation of living mice. Cell Res (2011) 1.48
Defective DNA base excision repair in brain from individuals with Alzheimer's disease and amnestic mild cognitive impairment. Nucleic Acids Res (2007) 1.48
Fabrication of Graphene/Polyaniline Composite Paper via In Situ Anodic Electropolymerization for High-Performance Flexible Electrode. ACS Nano (2009) 1.47
Efficacy of catheter ablation and surgical CryoMaze procedure in patients with long-lasting persistent atrial fibrillation and rheumatic heart disease: a randomized trial. Eur Heart J (2010) 1.47
Human cerebral neuropathology of Type 2 diabetes mellitus. Biochim Biophys Acta (2008) 1.46
High fat diet increases hippocampal oxidative stress and cognitive impairment in aged mice: implications for decreased Nrf2 signaling. J Neurochem (2010) 1.43
Involvement of inflammation, degradation, and apoptosis in a mouse model of glaucoma. J Biol Chem (2005) 1.43
Doped graphene sheets as anode materials with superhigh rate and large capacity for lithium ion batteries. ACS Nano (2011) 1.43
Morphological and physiological responses to sediment type and light availability in roots of the submerged plant Myriophyllum spicatum. Ann Bot (2007) 1.42
Down-regulation of signal transducer and activator of transcription 3 expression using vector-based small interfering RNAs suppresses growth of human prostate tumor in vivo. Clin Cancer Res (2005) 1.40
Abeta solubility and deposition during AD progression and in APPxPS-1 knock-in mice. Neurobiol Dis (2007) 1.40
A graphene-pure-sulfur sandwich structure for ultrafast, long-life lithium-sulfur batteries. Adv Mater (2013) 1.40
Increased energy expenditure, dietary fat wasting, and resistance to diet-induced obesity in mice lacking renin. Cell Metab (2007) 1.39
DWARF AND LOW-TILLERING, a new member of the GRAS family, plays positive roles in brassinosteroid signaling in rice. Plant J (2009) 1.38
Redox proteomic identification of 4-hydroxy-2-nonenal-modified brain proteins in amnestic mild cognitive impairment: insight into the role of lipid peroxidation in the progression and pathogenesis of Alzheimer's disease. Neurobiol Dis (2008) 1.38
A conformational switch in complexin is required for synaptotagmin to trigger synaptic fusion. Nat Struct Mol Biol (2011) 1.37
Nicastrin is critical for stability and trafficking but not association of other presenilin/gamma-secretase components. J Biol Chem (2005) 1.37