Published in J Am Soc Nephrol on December 21, 2005
Allosteric modulation of DNA by small molecules. Proc Natl Acad Sci U S A (2009) 1.61
Cyclic pyrrole-imidazole polyamides targeted to the androgen response element. J Am Chem Soc (2009) 1.21
Structural basis for cyclic Py-Im polyamide allosteric inhibition of nuclear receptor binding. J Am Chem Soc (2010) 1.15
HPV episome levels are potently decreased by pyrrole-imidazole polyamides. Antiviral Res (2011) 1.11
Quantitating the concentration of Py-Im polyamide-fluorescein conjugates in live cells. Bioorg Med Chem Lett (2008) 1.08
In vivo imaging of pyrrole-imidazole polyamides with positron emission tomography. Proc Natl Acad Sci U S A (2008) 1.07
Gene expression changes in a tumor xenograft by a pyrrole-imidazole polyamide. Proc Natl Acad Sci U S A (2012) 1.04
Direct inhibition of the DNA-binding activity of POU transcription factors Pit-1 and Brn-3 by selective binding of a phenyl-furan-benzimidazole dication. Nucleic Acids Res (2008) 1.04
Renoprotection by statins is linked to a decrease in renal oxidative stress, TGF-beta, and fibronectin with concomitant increase in nitric oxide bioavailability. Am J Physiol Renal Physiol (2008) 1.01
Guiding the design of synthetic DNA-binding molecules with massively parallel sequencing. J Am Chem Soc (2012) 0.97
Single-dose pharmacokinetic and toxicity analysis of pyrrole-imidazole polyamides in mice. Cancer Chemother Pharmacol (2012) 0.97
Enhancing the cellular uptake of Py-Im polyamides through next-generation aryl turns. Nucleic Acids Res (2011) 0.93
Pretranscriptional regulation of Tgf-beta1 by PI polyamide prevents scarring and accelerates wound healing of the cornea after exposure to alkali. Mol Ther (2009) 0.91
Solution-phase synthesis of pyrrole-imidazole polyamides. J Am Chem Soc (2009) 0.89
Programmable DNA-binding small molecules. Bioorg Med Chem (2013) 0.89
Correlation of local effects of DNA sequence and position of β-alanine inserts with polyamide-DNA complex binding affinities and kinetics. Biochemistry (2012) 0.88
Pyrrole-imidazole hairpin polyamides with high affinity at 5'-CGCG-3' DNA sequence; influence of cytosine methylation on binding. Nucleic Acids Res (2008) 0.86
Synthesis of cyclic Py-Im polyamide libraries. J Org Chem (2012) 0.84
Dendritic cells and macrophages in kidney disease. Clin Exp Nephrol (2009) 0.84
Protective effect of TRPV1 against renal fibrosis via inhibition of TGF-β/Smad signaling in DOCA-salt hypertension. Mol Med (2011) 0.83
DNA sequence selectivity of hairpin polyamide turn units. Bioorg Med Chem Lett (2009) 0.82
Expanding the repertoire of natural product-inspired ring pairs for molecular recognition of DNA. Org Lett (2011) 0.82
Pyrrole-imidazole polyamide targeting transforming growth factor β1 ameliorates encapsulating peritoneal sclerosis. Perit Dial Int (2012) 0.78
Polyamide curvature and DNA sequence selective recognition: use of 4-aminobenzamide to adjust curvature. Med Chem (2009) 0.78
Quantitation of pyrrole-imidazole polyamide in rat plasma by high-performance liquid chromatography coupled with UV detection. J Biomed Biotechnol (2012) 0.77
Oligomerization route to Py-Im polyamide macrocycles. Org Lett (2009) 0.77
Crosstalk of the Androgen Receptor with Transcriptional Collaborators: Potential Therapeutic Targets for Castration-Resistant Prostate Cancer. Cancers (Basel) (2017) 0.75
Preclinical Study of Novel Gene Silencer Pyrrole-Imidazole Polyamide Targeting Human TGF-β1 Promoter for Hypertrophic Scars in a Common Marmoset Primate Model. PLoS One (2015) 0.75
Structures of the bacterial ribosome at 3.5 A resolution. Science (2005) 12.63
Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine. Nat Biotechnol (2010) 9.01
The first metal-organic framework (MOF) of Imazethapyr and its SHG, piezoelectric and ferroelectric properties. Dalton Trans (2008) 8.86
Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell (2008) 7.93
Revealing global regulatory features of mammalian alternative splicing using a quantitative microarray platform. Mol Cell (2004) 7.32
Hydrogen-bonded ferroelectrics based on metal-organic coordination. J Am Chem Soc (2009) 6.69
Exploration of essential gene functions via titratable promoter alleles. Cell (2004) 5.21
Probing microRNAs with microarrays: tissue specificity and functional inference. RNA (2004) 4.91
Supramolecular bola-like ferroelectric: 4-methoxyanilinium tetrafluoroborate-18-crown-6. J Am Chem Soc (2011) 4.73
Diisopropylammonium chloride: a ferroelectric organic salt with a high phase transition temperature and practical utilization level of spontaneous polarization. Adv Mater (2011) 4.30
High-definition macromolecular composition of yeast RNA-processing complexes. Mol Cell (2004) 4.18
Improved virological outcomes in British Columbia concomitant with decreasing incidence of HIV type 1 drug resistance detection. Clin Infect Dis (2010) 3.12
A panoramic view of yeast noncoding RNA processing. Cell (2003) 3.11
A multiferroic perdeutero metal-organic framework. Angew Chem Int Ed Engl (2011) 2.88
DAPK1 interaction with NMDA receptor NR2B subunits mediates brain damage in stroke. Cell (2010) 2.87
Net primary production of Chinese croplands from 1950 to 1999. Ecol Appl (2007) 2.61
Structural basis for mRNA and tRNA positioning on the ribosome. Proc Natl Acad Sci U S A (2006) 2.55
Structural basis for aminoglycoside inhibition of bacterial ribosome recycling. Nat Struct Mol Biol (2007) 2.54
Identification of a novel non-coding RNA, MIAT, that confers risk of myocardial infarction. J Hum Genet (2006) 2.41
Effect of type 2 diabetes on risk for malignancies includes hepatocellular carcinoma in chronic hepatitis C. Hepatology (2013) 2.36
Alternative splicing of conserved exons is frequently species-specific in human and mouse. Trends Genet (2005) 2.26
The new models of the human telomere d[AGGG(TTAGGG)3] in K+ solution. Bioorg Med Chem (2006) 2.20
Genome-wide analysis of mouse transcripts using exon microarrays and factor graphs. Nat Genet (2005) 2.15
The Adamkiewicz artery: demonstration by intra-arterial computed tomographic angiography. Eur J Cardiothorac Surg (2006) 2.15
Early outcome of folding mitral valve repair technique without resection for mitral valve prolapse in 60 patients. J Thorac Cardiovasc Surg (2012) 2.06
Hyperglycemia alters PI3k and Akt signaling and leads to endothelial cell proliferative dysfunction. Am J Physiol Heart Circ Physiol (2005) 1.94
Intensified chemotherapy increases the survival rates in patients with stage 4 neuroblastoma with MYCN amplification. J Pediatr Hematol Oncol (2002) 1.94
HLA DRB10405-DQB10401 haplotype is associated with autoimmune pancreatitis in the Japanese population. Gastroenterology (2002) 1.92
Adenomatous polyposis coli (APC) differentially regulates beta-catenin phosphorylation and ubiquitination in colon cancer cells. J Biol Chem (2006) 1.86
IKK mediates ischemia-induced neuronal death. Nat Med (2005) 1.83
Functional coordination of alternative splicing in the mammalian central nervous system. Genome Biol (2007) 1.80
Mature adipocyte-derived dedifferentiated fat cells exhibit multilineage potential. J Cell Physiol (2008) 1.79
Kruppel-like factor 4 is acetylated by p300 and regulates gene transcription via modulation of histone acetylation. J Biol Chem (2007) 1.78
The AlkB domain of mammalian ABH8 catalyzes hydroxylation of 5-methoxycarbonylmethyluridine at the wobble position of tRNA. Angew Chem Int Ed Engl (2010) 1.76
Acute type A dissection: conservative methods provide consistently low mortality. Ann Thorac Surg (2002) 1.75
Impact of infliximab therapy after early endoscopic recurrence following ileocolonic resection of Crohn's disease: a prospective pilot study. Inflamm Bowel Dis (2009) 1.75
Vascular gene expression in nonneoplastic and malignant brain. Am J Pathol (2004) 1.71
Nephritis-associated plasmin receptor and acute poststreptococcal glomerulonephritis: characterization of the antigen and associated immune response. J Am Soc Nephrol (2004) 1.67
Gene expression profiling in a renal cell carcinoma cell line: dissecting VHL and hypoxia-dependent pathways. Mol Cancer Res (2003) 1.67
Azide-bridged one-dimensional Mn(III) polymers: effects of side group of Schiff base ligands on structure and magnetism. Inorg Chem (2007) 1.65
Mature, adipocyte derived, dedifferentiated fat cells can differentiate into smooth muscle-like cells and contribute to bladder tissue regeneration. J Urol (2009) 1.65
Statistical resynchronization and Bayesian detection of periodically expressed genes. Nucleic Acids Res (2004) 1.64
VEGF receptor-2 Y951 signaling and a role for the adapter molecule TSAd in tumor angiogenesis. EMBO J (2005) 1.63
Losartan improves the impaired function of endothelial progenitor cells in hypertension via an antioxidant effect. Hypertens Res (2007) 1.62
MDCT detection of double right coronary artery arising from a single ostium in the right sinus of Valsalva: report of 2 cases. Int J Cardiol (2006) 1.62
Patterns of exon-intron architecture variation of genes in eukaryotic genomes. BMC Genomics (2009) 1.61
Transplantation of mature adipocyte-derived dedifferentiated fat (DFAT) cells improves urethral sphincter contractility in a rat model. Int J Urol (2011) 1.61
Diisopropylammonium bromide is a high-temperature molecular ferroelectric crystal. Science (2013) 1.61
Specificity of Distalless repression and limb primordia development by abdominal Hox proteins. Dev Cell (2002) 1.61
Additive antioxidative effects of azelnidipine on angiotensin receptor blocker olmesartan treatment for type 2 diabetic patients with albuminuria. Hypertens Res (2011) 1.59
Complement 3 activates the renal renin-angiotensin system by induction of epithelial-to-mesenchymal transition of the nephrotubulus in mice. Am J Physiol Renal Physiol (2013) 1.59
Nuclear factor-kappaB contributes to infarction after permanent focal ischemia. Stroke (2004) 1.58
A novel gene silencer, pyrrole-imidazole polyamide targeting human lectin-like oxidized low-density lipoprotein receptor-1 gene improves endothelial cell function. J Hypertens (2009) 1.58
X-ray crystal structures of the WT and a hyper-accurate ribosome from Escherichia coli. Proc Natl Acad Sci U S A (2003) 1.58
Polymorphism of antigen MPT64 in Mycobacterium tuberculosis strains. J Clin Microbiol (2013) 1.56
Prediction and testing of novel transcriptional networks regulating embryonic stem cell self-renewal and commitment. Cell Stem Cell (2007) 1.56
Qualitative and quantitative changes in coronary plaque associated with atorvastatin therapy. Circ J (2009) 1.56
Henoch-schönlein purpura complicated by reversible posterior leukoencephalopathy syndrome. Pediatr Emerg Care (2010) 1.55
X-ray fluorescence microscopy reveals large-scale relocalization and extracellular translocation of cellular copper during angiogenesis. Proc Natl Acad Sci U S A (2007) 1.55
The follow-up evaluation of electrocardiogram and arrhythmias in children with fulminant myocarditis. Circ J (2011) 1.55
Effect of skin care with an emollient containing a high water content on mild uremic pruritus. Ther Apher Dial (2004) 1.51
Complement 3 is involved in the synthetic phenotype and exaggerated growth of vascular smooth muscle cells from spontaneously hypertensive rats. Hypertension (2004) 1.51
Formation of the G-quadruplex and i-motif structures in retinoblastoma susceptibility genes (Rb). Nucleic Acids Res (2006) 1.49
Electrophysiological characteristics of idiopathic ventricular tachycardia in children. Circ J (2011) 1.49
Growth characteristics, angiotensin II generation, and microarray-determined gene expression in vascular smooth muscle cells from young spontaneously hypertensive rats. J Hypertens (2002) 1.48
Aortic valve replacement in Behcet's disease: surgical modification to prevent valve detachment. Eur J Cardiothorac Surg (2009) 1.48
Clinical parameter and Th17 related to lymphocytes infiltrating degree of labial salivary gland in primary Sjögren's syndrome. Clin Rheumatol (2014) 1.47
Evaluation of serum fetuin-A relationships with biochemical parameters in patients on hemodialysis. Clin Exp Nephrol (2007) 1.47
Comparison of coronary sinus morphology in patients with and without atrioventricular nodal reentrant tachycardia by intracardiac echocardiography. J Cardiovasc Electrophysiol (2004) 1.46
Multiple papillary fibroelastoma in left ventricle associated with obstructive hypertrophic cardiomyopathy. Interact Cardiovasc Thorac Surg (2009) 1.45
KLF4 interacts with beta-catenin/TCF4 and blocks p300/CBP recruitment by beta-catenin. Mol Cell Biol (2009) 1.44
Use of a whole blood rapid panel test for heart-type fatty acid-binding protein in patients with acute chest pain: comparison with rapid troponin T and myoglobin tests. Am J Med (2003) 1.44
Major vascular involvement in Behçet's disease: a retrospective study of 796 patients. Clin Rheumatol (2013) 1.44
A single-molecule platform for investigation of interactions between G-quadruplexes and small-molecule ligands. Nat Chem (2011) 1.43
Effect of eplerenone on endothelial progenitor cells and oxidative stress in ischemic hindlimb. Am J Hypertens (2010) 1.43
Haplotype-based case-control study of the human CYP4F2 gene and essential hypertension in Japanese subjects. Hypertens Res (2008) 1.43
A systematic review of the effectiveness of oral health promotion activities among patients with cardiovascular disease. Int J Cardiol (2010) 1.43
Effect of fluvastatin on progression of coronary atherosclerotic plaque evaluated by virtual histology intravascular ultrasound. JACC Cardiovasc Interv (2009) 1.43
Renal involvement and followup of 130 patients with primary Sjögren's syndrome. J Rheumatol (2007) 1.43
Distinct functions of homeodomain-containing and homeodomain-less isoforms encoded by homothorax. Genes Dev (2006) 1.42
Associations between salivary gland histopathologic diagnoses and phenotypic features of Sjögren's syndrome among 1,726 registry participants. Arthritis Rheum (2011) 1.42
Zinc-finger transcriptional factor Sall1 induces angiogenesis by activation of the gene for VEGF-A. Hypertens Res (2009) 1.42