Published in Nucleic Acids Res on March 31, 2006
UBF activates RNA polymerase I transcription by stimulating promoter escape. EMBO J (2006) 1.20
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Chromatin: linking structure and function in the nucleolus. Chromosoma (2008) 1.14
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hALP, a novel transcriptional U three protein (t-UTP), activates RNA polymerase I transcription by binding and acetylating the upstream binding factor (UBF). J Biol Chem (2010) 0.90
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CK2-mediated stimulation of Pol I transcription by stabilization of UBF-SL1 interaction. Nucleic Acids Res (2006) 0.88
A RUNX2-HDAC1 co-repressor complex regulates rRNA gene expression by modulating UBF acetylation. J Cell Sci (2012) 0.88
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Cell cycle-dependent acetylation of Rb2/p130 in NIH3T3 cells. Oncogene (2010) 0.80
Transcriptional repressor NIR functions in the ribosome RNA processing of both 40S and 60S subunits. PLoS One (2012) 0.78
ESET methylates UBF at K232/254 and regulates nucleolar heterochromatin plasticity and rDNA transcription. Nucleic Acids Res (2013) 0.77
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In exponentially growing Saccharomyces cerevisiae cells, rRNA synthesis is determined by the summed RNA polymerase I loading rate rather than by the number of active genes. Mol Cell Biol (2003) 2.88
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An immediate response of ribosomal transcription to growth factor stimulation in mammals is mediated by ERK phosphorylation of UBF. Mol Cell (2001) 2.35
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Stimulation of c-MYC transcriptional activity and acetylation by recruitment of the cofactor CBP. EMBO Rep (2003) 2.21
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p53 represses ribosomal gene transcription. Oncogene (1999) 2.08
Acetylation control of the retinoblastoma tumour-suppressor protein. Nat Cell Biol (2001) 2.05
Phosphorylation by G1-specific cdk-cyclin complexes activates the nucleolar transcription factor UBF. EMBO J (1999) 2.04
Cell cycle-dependent regulation of RNA polymerase I transcription: the nucleolar transcription factor UBF is inactive in mitosis and early G1. Proc Natl Acad Sci U S A (1999) 2.04
Differential phosphorylation and localization of the transcription factor UBF in vivo in response to serum deprivation. In vitro dephosphorylation of UBF reduces its transactivation properties. J Biol Chem (1992) 2.02
The nucleolar transcription factor mUBF is phosphorylated by casein kinase II in the C-terminal hyperacidic tail which is essential for transactivation. EMBO J (1992) 1.94
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UBF-binding site arrays form pseudo-NORs and sequester the RNA polymerase I transcription machinery. Genes Dev (2004) 1.88
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RNA polymerase I associated factor 53 binds to the nucleolar transcription factor UBF and functions in specific rDNA transcription. EMBO J (1996) 1.48
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The HMG box-containing nucleolar transcription factor UBF interacts with a specific subunit of RNA polymerase I. EMBO J (1994) 1.44
Phosphorylation of UBF at serine 388 is required for interaction with RNA polymerase I and activation of rDNA transcription. Proc Natl Acad Sci U S A (2001) 1.33
The role of acetylation in rDNA transcription. Nucleic Acids Res (2001) 1.30
Recruitment of TATA-binding protein-TAFI complex SL1 to the human ribosomal DNA promoter is mediated by the carboxy-terminal activation domain of upstream binding factor (UBF) and is regulated by UBF phosphorylation. Mol Cell Biol (1999) 1.30
Constitutive and strong association of PAF53 with RNA polymerase I. Chromosoma (1997) 1.22
Overlapping functions of the pRb family in the regulation of rRNA synthesis. Mol Cell Biol (2001) 1.18
Rb and p130 regulate RNA polymerase I transcription: Rb disrupts the interaction between UBF and SL-1. Oncogene (2000) 1.17
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Putative involvement of the histone acetyltransferase Tip60 in ribosomal gene transcription. Nucleic Acids Res (2004) 1.03
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The composition of the RNA polymerase I transcription machinery switches from initiation to elongation mode. FEBS Lett (2004) 0.98
Rapid isolation of nucleoli from detergent purified nuclei of various tumor and tissue culture cells. Exp Cell Res (1974) 0.87
A kinetic framework for a mammalian RNA polymerase in vivo. Science (2002) 4.42
c-Myc associates with ribosomal DNA and activates RNA polymerase I transcription. Nat Cell Biol (2005) 3.79
The nucleolar remodeling complex NoRC mediates heterochromatin formation and silencing of ribosomal gene transcription. Nat Genet (2002) 3.58
The epigenetics of rRNA genes: from molecular to chromosome biology. Annu Rev Cell Dev Biol (2008) 3.42
Interaction of noncoding RNA with the rDNA promoter mediates recruitment of DNMT3b and silencing of rRNA genes. Genes Dev (2010) 2.96
mTOR-dependent activation of the transcription factor TIF-IA links rRNA synthesis to nutrient availability. Genes Dev (2004) 2.96
Intergenic transcripts regulate the epigenetic state of rRNA genes. Mol Cell (2006) 2.89
Nuclear actin and myosin I are required for RNA polymerase I transcription. Nat Cell Biol (2004) 2.49
Mammalian Sir2 homolog SIRT7 is an activator of RNA polymerase I transcription. Genes Dev (2006) 2.47
Genetic inactivation of the transcription factor TIF-IA leads to nucleolar disruption, cell cycle arrest, and p53-mediated apoptosis. Mol Cell (2005) 2.46
The RNA polymerase I transcription machinery: an emerging target for the treatment of cancer. Annu Rev Pharmacol Toxicol (2010) 2.45
The chromatin remodeling complex NoRC targets HDAC1 to the ribosomal gene promoter and represses RNA polymerase I transcription. EMBO J (2002) 2.36
The nucleolus as a stress sensor: JNK2 inactivates the transcription factor TIF-IA and down-regulates rRNA synthesis. Genes Dev (2005) 2.13
ERK-dependent phosphorylation of the transcription initiation factor TIF-IA is required for RNA polymerase I transcription and cell growth. Mol Cell (2003) 1.98
TAF12 recruits Gadd45a and the nucleotide excision repair complex to the promoter of rRNA genes leading to active DNA demethylation. Mol Cell (2009) 1.97
Activation of RNA polymerase I transcription by cockayne syndrome group B protein and histone methyltransferase G9a. Mol Cell (2007) 1.96
CSB is a component of RNA pol I transcription. Mol Cell (2002) 1.93
PHF8 activates transcription of rRNA genes through H3K4me3 binding and H3K9me1/2 demethylation. Nat Struct Mol Biol (2010) 1.91
Cellular stress and nucleolar function. Cell Cycle (2005) 1.88
Identification of novel functional TBP-binding sites and general factor repertoires. EMBO J (2007) 1.77
The PHD finger/bromodomain of NoRC interacts with acetylated histone H4K16 and is sufficient for rDNA silencing. Curr Biol (2005) 1.75
Epigenetic mechanism of rRNA gene silencing: temporal order of NoRC-mediated histone modification, chromatin remodeling, and DNA methylation. Mol Cell Biol (2005) 1.66
The structure of NoRC-associated RNA is crucial for targeting the chromatin remodelling complex NoRC to the nucleolus. EMBO Rep (2008) 1.64
Nuclear myosin I acts in concert with polymeric actin to drive RNA polymerase I transcription. Genes Dev (2008) 1.63
The chromatin remodelling complex WSTF-SNF2h interacts with nuclear myosin 1 and has a role in RNA polymerase I transcription. EMBO Rep (2006) 1.59
The chromatin remodelling complex NoRC safeguards genome stability by heterochromatin formation at telomeres and centromeres. EMBO Rep (2013) 1.55
Class II (IIa)-selective histone deacetylase inhibitors. 1. Synthesis and biological evaluation of novel (aryloxopropenyl)pyrrolyl hydroxyamides. J Med Chem (2005) 1.51
Multiple interactions between RNA polymerase I, TIF-IA and TAF(I) subunits regulate preinitiation complex assembly at the ribosomal gene promoter. EMBO Rep (2002) 1.48
Modulation of RNA polymerase assembly dynamics in transcriptional regulation. Mol Cell (2008) 1.47
TFIIH plays an essential role in RNA polymerase I transcription. Cell (2002) 1.43
Epigenetic disruption of ribosomal RNA genes and nucleolar architecture in DNA methyltransferase 1 (Dnmt1) deficient cells. Nucleic Acids Res (2007) 1.42
Repression of RNA polymerase I upon stress is caused by inhibition of RNA-dependent deacetylation of PAF53 by SIRT7. Mol Cell (2013) 1.41
The NoRC complex mediates the heterochromatin formation and stability of silent rRNA genes and centromeric repeats. EMBO J (2010) 1.40
AMP-activated protein kinase adapts rRNA synthesis to cellular energy supply. Proc Natl Acad Sci U S A (2009) 1.40
NoRC-dependent nucleosome positioning silences rRNA genes. EMBO J (2006) 1.39
NuRD blocks reprogramming of mouse somatic cells into pluripotent stem cells. Stem Cells (2013) 1.35
The chromatin remodeling complex NoRC controls replication timing of rRNA genes. EMBO J (2004) 1.34
Phosphorylation at serine 75 is required for UV-mediated degradation of human Cdc25A phosphatase at the S-phase checkpoint. J Biol Chem (2003) 1.32
Reversible acetylation of the chromatin remodelling complex NoRC is required for non-coding RNA-dependent silencing. Nat Cell Biol (2009) 1.30
Nucleolar disruption in dopaminergic neurons leads to oxidative damage and parkinsonism through repression of mammalian target of rapamycin signaling. J Neurosci (2011) 1.20
The chromatin remodeling complex NoRC and TTF-I cooperate in the regulation of the mammalian rRNA genes in vivo. Nucleic Acids Res (2004) 1.16
Inhibitors of histone deacetylases as potential therapeutic tools for high-risk embryonal tumors of the nervous system of childhood. Int J Cancer (2007) 1.16
Recruitment of the nucleolar remodeling complex NoRC establishes ribosomal DNA silencing in chromatin. Mol Cell Biol (2004) 1.15
The nucleolus—guardian of cellular homeostasis and genome integrity. Chromosoma (2013) 1.14
The chromatin remodeling complex NuRD establishes the poised state of rRNA genes characterized by bivalent histone modifications and altered nucleosome positions. Proc Natl Acad Sci U S A (2012) 1.13
Activation of an endogenous suicide response after perturbation of rRNA synthesis leads to neurodegeneration in mice. J Neurosci (2008) 1.12
Phosphorylation by casein kinase 2 facilitates rRNA gene transcription by promoting dissociation of TIF-IA from elongating RNA polymerase I. Mol Cell Biol (2008) 1.10
A maize histone deacetylase and retinoblastoma-related protein physically interact and cooperate in repressing gene transcription. Plant Mol Biol (2003) 1.07
Intergenic transcripts originating from a subclass of ribosomal DNA repeats silence ribosomal RNA genes in trans. EMBO Rep (2009) 1.05
Human Cdc14B promotes progression through mitosis by dephosphorylating Cdc25 and regulating Cdk1/cyclin B activity. PLoS One (2011) 1.01
Histone modifications and chromatin dynamics: a focus on filamentous fungi. FEMS Microbiol Rev (2008) 1.01
Histone deacetylases in fungi: novel members, new facts. Nucleic Acids Res (2003) 0.98
HdaA, a major class 2 histone deacetylase of Aspergillus nidulans, affects growth under conditions of oxidative stress. Eukaryot Cell (2005) 0.96
Antisense down-regulation of lipocalin-interacting membrane receptor expression inhibits cellular internalization of lipocalin-1 in human NT2 cells. J Biol Chem (2003) 0.95
Proteasomal ATPases are associated with rDNA: the ubiquitin proteasome system plays a direct role in RNA polymerase I transcription. Biochim Biophys Acta (2008) 0.94
A model for the topology of active ribosomal RNA genes. EMBO Rep (2011) 0.93
Discovery of (aryloxopropenyl)pyrrolyl hydroxyamides as selective inhibitors of class IIa histone deacetylase homologue HD1-A. J Med Chem (2003) 0.92
A novel motif in fungal class 1 histone deacetylases is essential for growth and development of Aspergillus. Mol Biol Cell (2009) 0.92
A new amidohydrolase from Bordetella or Alcaligenes strain FB188 with similarities to histone deacetylases. J Bacteriol (2004) 0.92
Role of pescadillo and upstream binding factor in the proliferation and differentiation of murine myeloid cells. Mol Cell Biol (2004) 0.91
Linking rDNA transcription to the cellular energy supply. Cell Cycle (2010) 0.90
Histone methyltransferases in Aspergillus nidulans: evidence for a novel enzyme with a unique substrate specificity. Biochemistry (2004) 0.89
Identification of protein phosphorylation sites by combination of elastase digestion, immobilized metal affinity chromatography, and quadrupole-time of flight tandem mass spectrometry. Proteomics (2002) 0.88
Mad1 function in cell proliferation and transcriptional repression is antagonized by cyclin E/CDK2. J Biol Chem (2005) 0.87
Development of a species-specific RNA polymerase I-based shRNA expression vector. Nucleic Acids Res (2006) 0.86
Death-effector domain-containing protein DEDD is an inhibitor of mitotic Cdk1/cyclin B1. Proc Natl Acad Sci U S A (2007) 0.84
DNA sequence encoded repression of rRNA gene transcription in chromatin. Nucleic Acids Res (2010) 0.84
Regulation and processing of maize histone deacetylase Hda1 by limited proteolysis. Plant Cell (2003) 0.82
Novel insights into the functional role of three protein arginine methyltransferases in Aspergillus nidulans. Fungal Genet Biol (2010) 0.81
Dynamic subcellular partitioning of the nucleolar transcription factor TIF-IA under ribotoxic stress. Biochim Biophys Acta (2009) 0.80
Mechanism of inhibition of RNA polymerase I transcription by DNA-dependent protein kinase. Biol Chem (2002) 0.79
Chromatin-specific regulation of mammalian rDNA transcription by clustered TTF-I binding sites. PLoS Genet (2013) 0.79
Cell cycle dependent role of HDAC1 for proliferation control through modulating ribosomal DNA transcription. Cell Biol Int (2008) 0.78
In vitro phosphorylation and acetylation of the murine pocket protein Rb2/p130. PLoS One (2012) 0.78
3-(4-Aroyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamides as a new class of synthetic histone deacetylase inhibitors. 2. Effect of pyrrole-C2 and/or -C4 substitutions on biological activity. J Med Chem (2004) 0.76
Autoantibodies to NOR 90/hUBF: longterm clinical and serological followup in a patient with limited systemic sclerosis suggests an antigen driven immune response. J Rheumatol (2002) 0.75
Experiences with pre-precipitation of phosphorus in a vertical flow constructed wetland in Austria. Water Sci Technol (2013) 0.75
Molecular identification of PpHDAC1, the first histone deacetylase fron the slime mold Physarum polycephalum. Cell Biol Int (2002) 0.75