Published in EMBO J on December 02, 2004
Evaluating genome-scale approaches to eukaryotic DNA replication. Nat Rev Genet (2010) 2.04
Mouse Rif1 is a key regulator of the replication-timing programme in mammalian cells. EMBO J (2012) 1.85
Replication timing and transcriptional control: beyond cause and effect--part II. Curr Opin Genet Dev (2009) 1.84
ATP-dependent chromatin remodeling shapes the DNA replication landscape. Nat Struct Mol Biol (2008) 1.61
Replication timing as an epigenetic mark. Epigenetics (2009) 1.53
The impact of chromatin modifiers on the timing of locus replication in mouse embryonic stem cells. Genome Biol (2007) 1.49
Uncoupling global and fine-tuning replication timing determinants for mouse pericentric heterochromatin. J Cell Biol (2006) 1.41
The NoRC complex mediates the heterochromatin formation and stability of silent rRNA genes and centromeric repeats. EMBO J (2010) 1.40
NoRC-dependent nucleosome positioning silences rRNA genes. EMBO J (2006) 1.39
DNA replication timing. Cold Spring Harb Perspect Biol (2013) 1.38
TFIIIB subunit Bdp1p is required for periodic integration of the Ty1 retrotransposon and targeting of Isw2p to S. cerevisiae tDNAs. Genes Dev (2005) 1.33
Reversible acetylation of the chromatin remodelling complex NoRC is required for non-coding RNA-dependent silencing. Nat Cell Biol (2009) 1.30
Replication timing and epigenetic reprogramming of gene expression: a two-way relationship? Nat Rev Genet (2009) 1.22
JmjC enzyme KDM2A is a regulator of rRNA transcription in response to starvation. EMBO J (2010) 1.17
Chromatin: linking structure and function in the nucleolus. Chromosoma (2008) 1.14
CHD7 functions in the nucleolus as a positive regulator of ribosomal RNA biogenesis. Hum Mol Genet (2010) 1.13
Intergenic transcripts originating from a subclass of ribosomal DNA repeats silence ribosomal RNA genes in trans. EMBO Rep (2009) 1.05
Allelic inactivation of rDNA loci. Genes Dev (2009) 1.04
G2 phase chromatin lacks determinants of replication timing. J Cell Biol (2010) 1.01
DNA replication timing is deterministic at the level of chromosomal domains but stochastic at the level of replicons in Xenopus egg extracts. Nucleic Acids Res (2008) 0.96
Quantitative analysis of NOR expression in a B chromosome of the grasshopper Eyprepocnemis plorans. Chromosoma (2008) 0.89
Large-scale organization of ribosomal DNA chromatin is regulated by Tip5. Nucleic Acids Res (2013) 0.85
Identification and characterization of ToRC, a novel ISWI-containing ATP-dependent chromatin assembly complex. Genes Dev (2012) 0.84
Epigenetic engineering of ribosomal RNA genes enhances protein production. PLoS One (2009) 0.81
Knockdown of fbxl10/kdm2bb rescues chd7 morphant phenotype in a zebrafish model of CHARGE syndrome. Dev Biol (2013) 0.81
PcG-mediated higher-order chromatin structures modulate replication programs at the Drosophila BX-C. PLoS Genet (2013) 0.81
Changes in chromatin structure correlate with transcriptional activity of nucleolar rDNA in polytene chromosomes. Chromosoma (2008) 0.80
Murine esBAF chromatin remodeling complex subunits BAF250a and Brg1 are necessary to maintain and reprogram pluripotency-specific replication timing of select replication domains. Epigenetics Chromatin (2013) 0.79
The Human RNA Polymerase I Transcription Terminator Complex Acts as a Replication Fork Barrier That Coordinates the Progress of Replication with rRNA Transcription Activity. Mol Cell Biol (2015) 0.78
ACTIN-RELATED PROTEIN8 encodes an F-box protein localized to the nucleolus in Arabidopsis. Plant Cell Physiol (2008) 0.78
Reproduction of the FC/DFC units in nucleoli. Nucleus (2016) 0.77
RECQ5 helicase promotes resolution of conflicts between replication and transcription in human cells. J Cell Biol (2016) 0.77
The Epigenetic Pathways to Ribosomal DNA Silencing. Microbiol Mol Biol Rev (2016) 0.75
Nucleolar dominance and maternal control of 45S rDNA expression. Proc Biol Sci (2015) 0.75
The language of covalent histone modifications. Nature (2000) 44.92
DNA methylation patterns and epigenetic memory. Genes Dev (2002) 33.83
DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci. Nat Genet (2000) 5.72
ACF consists of two subunits, Acf1 and ISWI, that function cooperatively in the ATP-dependent catalysis of chromatin assembly. Genes Dev (1999) 3.85
Replication timing and transcriptional control: beyond cause and effect. Curr Opin Cell Biol (2002) 3.68
The nucleolar remodeling complex NoRC mediates heterochromatin formation and silencing of ribosomal gene transcription. Nat Genet (2002) 3.58
In exponentially growing Saccharomyces cerevisiae cells, rRNA synthesis is determined by the summed RNA polymerase I loading rate rather than by the number of active genes. Mol Cell Biol (2003) 2.88
Chromatin structures and transcription of rDNA in yeast Saccharomyces cerevisiae. Nucleic Acids Res (1993) 2.74
NoRC--a novel member of mammalian ISWI-containing chromatin remodeling machines. EMBO J (2001) 2.67
The chromatin remodeling complex NoRC targets HDAC1 to the ribosomal gene promoter and represses RNA polymerase I transcription. EMBO J (2002) 2.36
WSTF-ISWI chromatin remodeling complex targets heterochromatic replication foci. EMBO J (2002) 2.33
A family of chromatin remodeling factors related to Williams syndrome transcription factor. Proc Natl Acad Sci U S A (2000) 2.24
Molecular mechanisms mediating methylation-dependent silencing of ribosomal gene transcription. Mol Cell (2001) 2.24
Heritable gene silencing in lymphocytes delays chromatid resolution without affecting the timing of DNA replication. Nat Cell Biol (2003) 2.21
Purification and characterization of a human factor that assembles and remodels chromatin. J Biol Chem (2000) 2.13
HuCHRAC, a human ISWI chromatin remodelling complex contains hACF1 and two novel histone-fold proteins. EMBO J (2000) 2.11
Phosphorylation by G1-specific cdk-cyclin complexes activates the nucleolar transcription factor UBF. EMBO J (1999) 2.04
The epigenetics of nucleolar dominance. Trends Genet (2000) 1.83
Replicating by the clock. Nat Rev Mol Cell Biol (2003) 1.79
RPD3 is required for the inactivation of yeast ribosomal DNA genes in stationary phase. EMBO J (2002) 1.79
Transcription in the yeast rRNA gene locus: distribution of the active gene copies and chromatin structure of their flanking regulatory sequences. Mol Cell Biol (1995) 1.77
Mechanisms of nucleolar dominance in animals and plants. J Cell Biol (1985) 1.74
Replication of transcriptionally active chromatin. Nature (1995) 1.37
The chromatin remodeling complex NoRC and TTF-I cooperate in the regulation of the mammalian rRNA genes in vivo. Nucleic Acids Res (2004) 1.16
Chromatin structure and methylation of rat rRNA genes studied by formaldehyde fixation and psoralen cross-linking. Nucleic Acids Res (1997) 0.96
The ribosomal RNA gene cluster in aneuploid chickens: evidence for increased gene dosage and regulation of gene expression. J Cell Biol (1985) 0.86
Temporal order of replication of mouse ribosomal RNA genes during the cell cycle. Chromosoma (1997) 0.84
A kinetic framework for a mammalian RNA polymerase in vivo. Science (2002) 4.42
c-Myc associates with ribosomal DNA and activates RNA polymerase I transcription. Nat Cell Biol (2005) 3.79
The nucleolar remodeling complex NoRC mediates heterochromatin formation and silencing of ribosomal gene transcription. Nat Genet (2002) 3.58
The epigenetics of rRNA genes: from molecular to chromosome biology. Annu Rev Cell Dev Biol (2008) 3.42
Interaction of noncoding RNA with the rDNA promoter mediates recruitment of DNMT3b and silencing of rRNA genes. Genes Dev (2010) 2.96
mTOR-dependent activation of the transcription factor TIF-IA links rRNA synthesis to nutrient availability. Genes Dev (2004) 2.96
Intergenic transcripts regulate the epigenetic state of rRNA genes. Mol Cell (2006) 2.89
Nuclear actin and myosin I are required for RNA polymerase I transcription. Nat Cell Biol (2004) 2.49
Mammalian Sir2 homolog SIRT7 is an activator of RNA polymerase I transcription. Genes Dev (2006) 2.47
Genetic inactivation of the transcription factor TIF-IA leads to nucleolar disruption, cell cycle arrest, and p53-mediated apoptosis. Mol Cell (2005) 2.46
The RNA polymerase I transcription machinery: an emerging target for the treatment of cancer. Annu Rev Pharmacol Toxicol (2010) 2.45
The chromatin remodeling complex NoRC targets HDAC1 to the ribosomal gene promoter and represses RNA polymerase I transcription. EMBO J (2002) 2.36
The nucleolus as a stress sensor: JNK2 inactivates the transcription factor TIF-IA and down-regulates rRNA synthesis. Genes Dev (2005) 2.13
ERK-dependent phosphorylation of the transcription initiation factor TIF-IA is required for RNA polymerase I transcription and cell growth. Mol Cell (2003) 1.98
TAF12 recruits Gadd45a and the nucleotide excision repair complex to the promoter of rRNA genes leading to active DNA demethylation. Mol Cell (2009) 1.97
Activation of RNA polymerase I transcription by cockayne syndrome group B protein and histone methyltransferase G9a. Mol Cell (2007) 1.96
CSB is a component of RNA pol I transcription. Mol Cell (2002) 1.93
Inheritance of silent rDNA chromatin is mediated by PARP1 via noncoding RNA. Mol Cell (2012) 1.93
PHF8 activates transcription of rRNA genes through H3K4me3 binding and H3K9me1/2 demethylation. Nat Struct Mol Biol (2010) 1.91
Cellular stress and nucleolar function. Cell Cycle (2005) 1.88
Identification of novel functional TBP-binding sites and general factor repertoires. EMBO J (2007) 1.77
The PHD finger/bromodomain of NoRC interacts with acetylated histone H4K16 and is sufficient for rDNA silencing. Curr Biol (2005) 1.75
Epigenetic mechanism of rRNA gene silencing: temporal order of NoRC-mediated histone modification, chromatin remodeling, and DNA methylation. Mol Cell Biol (2005) 1.66
The structure of NoRC-associated RNA is crucial for targeting the chromatin remodelling complex NoRC to the nucleolus. EMBO Rep (2008) 1.64
Nuclear myosin I acts in concert with polymeric actin to drive RNA polymerase I transcription. Genes Dev (2008) 1.63
The chromatin remodelling complex WSTF-SNF2h interacts with nuclear myosin 1 and has a role in RNA polymerase I transcription. EMBO Rep (2006) 1.59
The chromatin remodelling complex NoRC safeguards genome stability by heterochromatin formation at telomeres and centromeres. EMBO Rep (2013) 1.55
Multiple interactions between RNA polymerase I, TIF-IA and TAF(I) subunits regulate preinitiation complex assembly at the ribosomal gene promoter. EMBO Rep (2002) 1.48
Modulation of RNA polymerase assembly dynamics in transcriptional regulation. Mol Cell (2008) 1.47
TFIIH plays an essential role in RNA polymerase I transcription. Cell (2002) 1.43
Epigenetic disruption of ribosomal RNA genes and nucleolar architecture in DNA methyltransferase 1 (Dnmt1) deficient cells. Nucleic Acids Res (2007) 1.42
Repression of RNA polymerase I upon stress is caused by inhibition of RNA-dependent deacetylation of PAF53 by SIRT7. Mol Cell (2013) 1.41
The NoRC complex mediates the heterochromatin formation and stability of silent rRNA genes and centromeric repeats. EMBO J (2010) 1.40
AMP-activated protein kinase adapts rRNA synthesis to cellular energy supply. Proc Natl Acad Sci U S A (2009) 1.40
NoRC-dependent nucleosome positioning silences rRNA genes. EMBO J (2006) 1.39
NuRD blocks reprogramming of mouse somatic cells into pluripotent stem cells. Stem Cells (2013) 1.35
Reversible acetylation of the chromatin remodelling complex NoRC is required for non-coding RNA-dependent silencing. Nat Cell Biol (2009) 1.30
Potential roles for ubiquitin and the proteasome during ribosome biogenesis. Mol Cell Biol (2006) 1.25
Nucleolar disruption in dopaminergic neurons leads to oxidative damage and parkinsonism through repression of mammalian target of rapamycin signaling. J Neurosci (2011) 1.20
Inflammasome-activated caspase 7 cleaves PARP1 to enhance the expression of a subset of NF-κB target genes. Mol Cell (2012) 1.17
The chromatin remodeling complex NoRC and TTF-I cooperate in the regulation of the mammalian rRNA genes in vivo. Nucleic Acids Res (2004) 1.16
Recruitment of the nucleolar remodeling complex NoRC establishes ribosomal DNA silencing in chromatin. Mol Cell Biol (2004) 1.15
The nucleolus—guardian of cellular homeostasis and genome integrity. Chromosoma (2013) 1.14
The nucleolus and transcription of ribosomal genes. Biol Cell (2004) 1.13
The chromatin remodeling complex NuRD establishes the poised state of rRNA genes characterized by bivalent histone modifications and altered nucleosome positions. Proc Natl Acad Sci U S A (2012) 1.13
Activation of an endogenous suicide response after perturbation of rRNA synthesis leads to neurodegeneration in mice. J Neurosci (2008) 1.12
Phosphorylation by casein kinase 2 facilitates rRNA gene transcription by promoting dissociation of TIF-IA from elongating RNA polymerase I. Mol Cell Biol (2008) 1.10
Nuclear envelope alterations generate an aging-like epigenetic pattern in mice deficient in Zmpste24 metalloprotease. Aging Cell (2010) 1.06
Intergenic transcripts originating from a subclass of ribosomal DNA repeats silence ribosomal RNA genes in trans. EMBO Rep (2009) 1.05
Formation of nuclear heterochromatin: the nucleolar point of view. Epigenetics (2012) 1.04
Human Cdc14B promotes progression through mitosis by dephosphorylating Cdc25 and regulating Cdk1/cyclin B activity. PLoS One (2011) 1.01
Organization of human replicon: singles or zipping couples? J Struct Biol (2008) 1.01
Atomic scissors: a new method of tracking the 5-bromo-2'-deoxyuridine-labeled DNA in situ. PLoS One (2012) 1.00
Most anti-BrdU antibodies react with 2'-deoxy-5-ethynyluridine -- the method for the effective suppression of this cross-reactivity. PLoS One (2012) 0.97
Positioning of NORs and NOR-bearing chromosomes in relation to nucleoli. J Struct Biol (2007) 0.97
Proteasomal ATPases are associated with rDNA: the ubiquitin proteasome system plays a direct role in RNA polymerase I transcription. Biochim Biophys Acta (2008) 0.94
Acetylation of UBF changes during the cell cycle and regulates the interaction of UBF with RNA polymerase I. Nucleic Acids Res (2006) 0.94
A model for the topology of active ribosomal RNA genes. EMBO Rep (2011) 0.93
Role of pescadillo and upstream binding factor in the proliferation and differentiation of murine myeloid cells. Mol Cell Biol (2004) 0.91
Linking rDNA transcription to the cellular energy supply. Cell Cycle (2010) 0.90
Identification of protein phosphorylation sites by combination of elastase digestion, immobilized metal affinity chromatography, and quadrupole-time of flight tandem mass spectrometry. Proteomics (2002) 0.88
Spatio-temporal dynamics at rDNA foci: global switching between DNA replication and transcription. J Cell Biochem (2005) 0.87
In situ reverse transcription: the magic of strength and anonymity. Nucleic Acids Res (2010) 0.87
Formation of nuclear splicing factor compartments is independent of lamins A/C. Mol Biol Cell (2004) 0.86
Development of a species-specific RNA polymerase I-based shRNA expression vector. Nucleic Acids Res (2006) 0.86
Secretory glands in cercaria of the neuropathogenic schistosome Trichobilharzia regenti - ultrastructural characterization, 3-D modelling, volume and pH estimations. Parasit Vectors (2011) 0.85
Death-effector domain-containing protein DEDD is an inhibitor of mitotic Cdk1/cyclin B1. Proc Natl Acad Sci U S A (2007) 0.84
DNA sequence encoded repression of rRNA gene transcription in chromatin. Nucleic Acids Res (2010) 0.84
The expanding role of PARPs in the establishment and maintenance of heterochromatin. FEBS J (2013) 0.83
ARTD2 activity is stimulated by RNA. Nucleic Acids Res (2014) 0.82
Tracking DNA and RNA sequences at high resolution. Methods Mol Biol (2014) 0.81
DTX3L and ARTD9 inhibit IRF1 expression and mediate in cooperation with ARTD8 survival and proliferation of metastatic prostate cancer cells. Mol Cancer (2014) 0.81
Dynamic subcellular partitioning of the nucleolar transcription factor TIF-IA under ribotoxic stress. Biochim Biophys Acta (2009) 0.80
Mechanism of inhibition of RNA polymerase I transcription by DNA-dependent protein kinase. Biol Chem (2002) 0.79
Chromatin-specific regulation of mammalian rDNA transcription by clustered TTF-I binding sites. PLoS Genet (2013) 0.79
Pontin is localized in nucleolar fibrillar centers. Chromosoma (2008) 0.79
Noncoding RNAs link PARP1 to heterochromatin. Cell Cycle (2012) 0.78
A New Method of the Visualization of the Double-Stranded Mitochondrial and Nuclear DNA. PLoS One (2013) 0.77
Replication-coupled modulation of early replicating chromatin domains detected by anti-actin antibody. J Cell Biochem (2005) 0.77
Electron microscopy in situ hybridization: tracking of DNA and RNA sequences at high resolution. Methods Mol Biol (2007) 0.77
Searching for active ribosomal genes in situ: light microscopy in light of the electron beam. J Struct Biol (2002) 0.77
Helicase CHD4 is an epigenetic coregulator of PAX3-FOXO1 in alveolar rhabdomyosarcoma. J Clin Invest (2016) 0.75
Corrigendum: Pramel7 mediates ground-state pluripotency through proteasomal-epigenetic combined pathways. Nat Cell Biol (2017) 0.75
Autoantibodies to NOR 90/hUBF: longterm clinical and serological followup in a patient with limited systemic sclerosis suggests an antigen driven immune response. J Rheumatol (2002) 0.75