Published in Nat Cell Biol on September 11, 2011
Self-consumption: the interplay of autophagy and apoptosis. Nat Rev Mol Cell Biol (2014) 3.38
Molecular control of animal cell cytokinesis. Nat Cell Biol (2012) 2.45
Ubiquitination and selective autophagy. Cell Death Differ (2012) 2.12
p62: a versatile multitasker takes on cancer. Trends Biochem Sci (2012) 1.93
Aggrephagy: selective disposal of protein aggregates by macroautophagy. Int J Cell Biol (2012) 1.52
Receptor protein complexes are in control of autophagy. Autophagy (2012) 1.49
Mitochondrial network size scaling in budding yeast. Science (2012) 1.44
Autophagy in stem cells. Autophagy (2013) 1.43
Centralspindlin: at the heart of cytokinesis. Cytoskeleton (Hoboken) (2012) 1.24
Cellular and metabolic functions for autophagy in cancer cells. Trends Cell Biol (2014) 1.16
Autophagy and cell growth--the yin and yang of nutrient responses. J Cell Sci (2012) 1.14
The ESCRT machinery: from the plasma membrane to endosomes and back again. Crit Rev Biochem Mol Biol (2014) 1.12
Endocytic transport and cytokinesis: from regulation of the cytoskeleton to midbody inheritance. Trends Cell Biol (2013) 1.11
Autophagy and genomic integrity. Cell Death Differ (2013) 1.07
NBR1 enables autophagy-dependent focal adhesion turnover. J Cell Biol (2016) 1.05
Autophagy: a targetable linchpin of cancer cell metabolism. Trends Endocrinol Metab (2013) 1.04
The role of ALFY in selective autophagy. Cell Death Differ (2012) 1.00
Rho GTPases as regulators of mitosis and cytokinesis in mammalian cells. Small GTPases (2014) 1.00
Centrosome asymmetry and inheritance during animal development. Curr Opin Cell Biol (2012) 0.99
Centrosome-dependent asymmetric inheritance of the midbody ring in Drosophila germline stem cell division. Mol Biol Cell (2013) 0.98
Resurrecting remnants: the lives of post-mitotic midbodies. Trends Cell Biol (2012) 0.98
Apoptotic regulators promote cytokinetic midbody degradation in C. elegans. J Cell Biol (2012) 0.97
Autophagy plays a critical role in the degradation of active RHOA, the control of cell cytokinesis, and genomic stability. Cancer Res (2013) 0.97
Peroxisomal Atg37 binds Atg30 or palmitoyl-CoA to regulate phagophore formation during pexophagy. J Cell Biol (2014) 0.97
Incisive imaging and computation for cellular mysteries: lessons from abscission. Cell (2013) 0.95
Cancer stem cells and their role in metastasis. Pharmacol Ther (2013) 0.93
Autophagy and mTORC1 regulate the stochastic phase of somatic cell reprogramming. Nat Cell Biol (2015) 0.91
p27(Kip1) controls cytokinesis via the regulation of citron kinase activation. J Clin Invest (2012) 0.90
Tightrope act: autophagy in stem cell renewal, differentiation, proliferation, and aging. Cell Mol Life Sci (2012) 0.86
Mechanisms of Selective Autophagy in Normal Physiology and Cancer. J Mol Biol (2016) 0.85
Mechanistic insights into selective autophagy pathways: lessons from yeast. Nat Rev Mol Cell Biol (2016) 0.85
Midbody: from cellular junk to regulator of cell polarity and cell fate. Curr Opin Cell Biol (2015) 0.84
A mitotic kinase scaffold depleted in testicular seminomas impacts spindle orientation in germ line stem cells. Elife (2015) 0.83
Prenatal Neurogenesis in Autism Spectrum Disorders. Front Chem (2016) 0.82
The equatorial position of the metaphase plate ensures symmetric cell divisions. Elife (2015) 0.81
Beyond cytokinesis: the emerging roles of CEP55 in tumorigenesis. Oncogene (2015) 0.81
Gradual recruitment and selective clearing generate germ plasm aggregates in the zebrafish embryo. Bioarchitecture (2014) 0.80
CETN1 is a cancer testis antigen with expression in prostate and pancreatic cancers. Biomark Res (2013) 0.80
Autophagy and cellular senescence mediated by Sox2 suppress malignancy of cancer cells. PLoS One (2013) 0.80
Centrosome-intrinsic mechanisms modulate centrosome integrity during fever. Mol Biol Cell (2015) 0.80
Stereotyped distribution of midbody remnants in early C. elegans embryos requires cell death genes and is dispensable for development. Cell Res (2013) 0.80
MAP1B Interaction with the FW Domain of the Autophagic Receptor Nbr1 Facilitates Its Association to the Microtubule Network. Int J Cell Biol (2012) 0.79
Cross-regulation between Aurora B and Citron kinase controls midbody architecture in cytokinesis. Open Biol (2016) 0.79
HIV Assembly and Budding: Ca(2+) Signaling and Non-ESCRT Proteins Set the Stage. Mol Biol Int (2012) 0.79
Novel role for the midbody in primary ciliogenesis by polarized epithelial cells. J Cell Biol (2016) 0.79
Prognostic relevance of autophagy markers LC3B and p62 in esophageal adenocarcinomas. Oncotarget (2016) 0.79
The vertebrate-specific Kinesin-6, Kif20b, is required for normal cytokinesis of polarized cortical stem cells and cerebral cortex size. Development (2013) 0.78
Lipidome of midbody released from neural stem and progenitor cells during mammalian cortical neurogenesis. Front Cell Neurosci (2015) 0.78
Phosphorylation of NBR1 by GSK3 modulates protein aggregation. Autophagy (2014) 0.78
PRL-3 disrupts epithelial architecture by altering the post-mitotic midbody position. J Cell Sci (2016) 0.78
Autophagy and the Cell Cycle: A Complex Landscape. Front Oncol (2017) 0.77
Centrosome age regulates kinetochore-microtubule stability and biases chromosome mis-segregation. Elife (2015) 0.77
DNA asymmetry in stem cells - immortal or mortal? J Cell Sci (2013) 0.77
Molecular mechanisms controlling asymmetric and symmetric self-renewal of cancer stem cells. J Anal Sci Technol (2015) 0.76
Cut or NoCut: the role of JADE1S in regulating abscission checkpoint. Cell Cycle (2015) 0.76
Autophagy in adhesion and migration. J Cell Sci (2016) 0.76
A function for the midbody remnant in embryonic patterning. Commun Integr Biol (2014) 0.76
Binding of Kif23-iso1/CHO1 to 14-3-3 is regulated by sequential phosphorylations at two LATS kinase consensus sites. PLoS One (2015) 0.76
Focal adhesions control cleavage furrow shape and spindle tilt during mitosis. Sci Rep (2016) 0.75
Organelle dynamics: Inheritance for pluripotency. Nat Rev Mol Cell Biol (2011) 0.75
Neural Stem Cells to Cerebral Cortex: Emerging Mechanisms Regulating Progenitor Behavior and Productivity. J Neurosci (2016) 0.75
Stephen Doxsey: at the (peri)center of things. J Cell Biol (2013) 0.75
C. elegans midbodies are released, phagocytosed and undergo LC3-dependent degradation independent of macroautophagy. J Cell Sci (2016) 0.75
Molecular characteristics of cancer stem-like cells derived from human breast cancer cells. Anticancer Res (2013) 0.75
TRIM17 contributes to autophagy of midbodies while actively sparing other targets from degradation. J Cell Sci (2016) 0.75
Mutation of Kinesin-6 Kif20b causes defects in cortical neuron polarization and morphogenesis. Neural Dev (2017) 0.75
Analyzing the functions of Rab11-effector proteins during cell division. Methods Cell Biol (2015) 0.75
An integrated overview of spatiotemporal organization and regulation in mitosis in terms of the proteins in the functional supercomplexes. Front Microbiol (2014) 0.75
Defective autophagy leads to the suppression of stem-like features of CD271(+) osteosarcoma cells. J Biomed Sci (2016) 0.75
Midbody remnant licenses primary cilia formation in epithelial cells. J Cell Biol (2016) 0.75
Understanding post-mitotic roles of the midbody during cell differentiation and polarization. Methods Cell Biol (2016) 0.75
Myosin Va plays essential roles in maintaining normal mitosis, enhancing tumor cell motility and viability. Oncotarget (2017) 0.75
Routes and machinery of primary cilium biogenesis. Cell Mol Life Sci (2017) 0.75
Keep it on the edge: The post-mitotic midbody as a polarity signal unit. Commun Integr Biol (2017) 0.75
A systematic review of the asymmetric inheritance of cellular organelles in eukaryotes: A critique of basic science validity and imprecision. PLoS One (2017) 0.75
The X-linked Deubiquitinase USP9X Is an Integral Component of Centrosome. J Biol Chem (2017) 0.75
Induced pluripotent stem cell lines derived from human somatic cells. Science (2007) 71.50
Autophagy in the pathogenesis of disease. Cell (2008) 34.68
Autophagy fights disease through cellular self-digestion. Nature (2008) 33.83
Reprogramming of human somatic cells to pluripotency with defined factors. Nature (2007) 30.84
A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature (2006) 24.52
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice. Nature (2006) 24.39
Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature (1999) 23.62
The role of autophagy during the early neonatal starvation period. Nature (2004) 22.40
p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy. J Biol Chem (2007) 21.73
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy (2007) 20.92
Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice. J Cell Biol (2005) 18.60
p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death. J Cell Biol (2005) 18.23
Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nat Rev Cancer (2008) 18.08
Human induced pluripotent stem cells free of vector and transgene sequences. Science (2009) 17.16
Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice. Cell (2007) 14.63
How to interpret LC3 immunoblotting. Autophagy (2007) 12.30
Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8. Science (2004) 10.77
Capturing and profiling adult hair follicle stem cells. Nat Biotechnol (2004) 10.35
A chemical method for fast and sensitive detection of DNA synthesis in vivo. Proc Natl Acad Sci U S A (2008) 10.09
Applying the principles of stem-cell biology to cancer. Nat Rev Cancer (2003) 8.95
Ambra1 regulates autophagy and development of the nervous system. Nature (2007) 6.94
A role for NBR1 in autophagosomal degradation of ubiquitinated substrates. Mol Cell (2009) 6.88
Live cell imaging distinguishes bona fide human iPS cells from partially reprogrammed cells. Nat Biotechnol (2009) 6.76
Orientation of asymmetric stem cell division by the APC tumor suppressor and centrosome. Science (2003) 6.72
Whole-exome sequencing identifies recessive WDR62 mutations in severe brain malformations. Nature (2010) 6.26
Sites of microtubule assembly and disassembly in the mitotic spindle. Cell (1986) 5.91
Homologous recombination in human embryonic stem cells. Nat Biotechnol (2003) 5.77
Protein turnover via autophagy: implications for metabolism. Annu Rev Nutr (2007) 5.75
Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content. Cell (2010) 5.57
Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells. Nat Genet (2010) 5.37
Aurora B-mediated abscission checkpoint protects against tetraploidization. Cell (2009) 5.26
Lithium induces autophagy by inhibiting inositol monophosphatase. J Cell Biol (2005) 5.21
The respective contributions of the mother and daughter centrioles to centrosome activity and behavior in vertebrate cells. J Cell Biol (2000) 4.97
Asymmetric inheritance of mother versus daughter centrosome in stem cell division. Science (2007) 4.59
The role of autophagy in mammalian development: cell makeover rather than cell death. Dev Cell (2008) 4.25
Animal cytokinesis: from parts list to mechanisms. Annu Rev Biochem (2006) 4.23
Centriolin anchoring of exocyst and SNARE complexes at the midbody is required for secretory-vesicle-mediated abscission. Cell (2005) 3.93
The tortoise and the hair: slow-cycling cells in the stem cell race. Cell (2009) 3.90
Cytokinesis: placing and making the final cut. Cell (2007) 3.90
Autophagy is essential for preimplantation development of mouse embryos. Science (2008) 3.55
At the acidic edge: emerging functions for lysosomal membrane proteins. Trends Cell Biol (2003) 3.26
Polarised asymmetric inheritance of accumulated protein damage in higher eukaryotes. PLoS Biol (2006) 3.06
Asymmetric centrosome inheritance maintains neural progenitors in the neocortex. Nature (2009) 3.03
Interaction codes within the family of mammalian Phox and Bem1p domain-containing proteins. J Biol Chem (2003) 3.02
Centrosomes in cellular regulation. Annu Rev Cell Dev Biol (2005) 2.89
Regulation of spermatogonial stem cell self-renewal in mammals. Annu Rev Cell Dev Biol (2008) 2.79
Dividing cellular asymmetry: asymmetric cell division and its implications for stem cells and cancer. Genes Dev (2009) 2.76
Terminal phase of cytokinesis in D-98s cells. J Cell Biol (1977) 2.64
Eating the endoplasmic reticulum: quality control by autophagy. Trends Cell Biol (2007) 2.60
Release of extracellular membrane particles carrying the stem cell marker prominin-1 (CD133) from neural progenitors and other epithelial cells. J Cell Sci (2005) 2.58
Fluorescence protease protection of GFP chimeras to reveal protein topology and subcellular localization. Nat Methods (2006) 2.42
Autophagy is activated in colorectal cancer cells and contributes to the tolerance to nutrient deprivation. Cancer Res (2007) 2.39
SEPA-1 mediates the specific recognition and degradation of P granule components by autophagy in C. elegans. Cell (2009) 2.35
Mechanisms of chaperone-mediated autophagy. Int J Biochem Cell Biol (2004) 2.27
Midbody and primary cilium of neural progenitors release extracellular membrane particles enriched in the stem cell marker prominin-1. J Cell Biol (2007) 2.19
Constitutive activation of chaperone-mediated autophagy in cells with impaired macroautophagy. Mol Biol Cell (2008) 2.14
Cytoplasmic dynein/dynactin mediates the assembly of aggresomes. Cell Motil Cytoskeleton (2002) 2.11
Mouse differentiating spermatogonia can generate germinal stem cells in vivo. Nat Cell Biol (2008) 2.05
A rational mechanism for combination treatment of Huntington's disease using lithium and rapamycin. Hum Mol Genet (2007) 2.03
Autophagy and the ubiquitin-proteasome system: collaborators in neuroprotection. Biochim Biophys Acta (2008) 1.73
Specification of the germ line. WormBook (2005) 1.71
Midbody ring disposal by autophagy is a post-abscission event of cytokinesis. Nat Cell Biol (2008) 1.70
Centriole age underlies asynchronous primary cilium growth in mammalian cells. Curr Biol (2009) 1.70
MCF7 side population cells with characteristics of cancer stem/progenitor cells express the tumor antigen MUC1. Cancer Res (2008) 1.66
Conversion of midbodies into germ cell intercellular bridges. Dev Biol (2007) 1.36
Both daughter cells traffic and exocytose membrane at the cleavage furrow during mammalian cytokinesis. J Cell Biol (2008) 1.33
Immuno-analysis and FACS sorting of adult muscle fiber-associated stem/precursor cells. Methods Mol Biol (2010) 1.16
Interactions with LC3 and polyubiquitin chains link nbr1 to autophagic protein turnover. FEBS Lett (2009) 1.10
Paxillin-Y118 phosphorylation contributes to the control of Src-induced anchorage-independent growth by FAK and adhesion. BMC Cancer (2009) 0.99
c-Jun NH2-terminal kinase is required for lineage-specific differentiation but not stem cell self-renewal. Mol Cell Biol (2010) 0.97
Reprogramming of human somatic cells to pluripotency with defined factors. Nature (2007) 30.84
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy (2007) 20.92
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Disease-specific induced pluripotent stem cells. Cell (2008) 16.95
Selective blockade of microRNA processing by Lin28. Science (2008) 14.39
Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA. Cell Stem Cell (2010) 14.18
Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells. Nat Biotechnol (2009) 11.18
Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts. Nat Genet (2009) 10.54
Somatic coding mutations in human induced pluripotent stem cells. Nature (2011) 9.50
Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells. Cell Stem Cell (2009) 8.97
Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl. Cancer Cell (2005) 7.99
Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming. Nat Biotechnol (2009) 7.59
Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis. Nature (2007) 7.55
Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells. Nature (2011) 7.43
Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells. Cell Stem Cell (2011) 7.41
Live cell imaging distinguishes bona fide human iPS cells from partially reprogrammed cells. Nat Biotechnol (2009) 6.76
miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis. Nat Cell Biol (2010) 6.67
Lin28 promotes transformation and is associated with advanced human malignancies. Nat Genet (2009) 6.35
MicroRNA-9a ensures the precise specification of sensory organ precursors in Drosophila. Genes Dev (2006) 6.30
Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes. Proc Natl Acad Sci U S A (2010) 6.15
Comprehensive methylome map of lineage commitment from haematopoietic progenitors. Nature (2010) 6.06
HoxB4 confers definitive lymphoid-myeloid engraftment potential on embryonic stem cell and yolk sac hematopoietic progenitors. Cell (2002) 5.71
Mechanisms of autoinhibition and STI-571/imatinib resistance revealed by mutagenesis of BCR-ABL. Cell (2003) 5.71
Complete genome sequence of the apicomplexan, Cryptosporidium parvum. Science (2004) 5.64
Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells. Nat Genet (2010) 5.37
The promise of induced pluripotent stem cells in research and therapy. Nature (2012) 5.05
Generation of induced pluripotent stem cells from human blood. Blood (2009) 4.92
Generation of human-induced pluripotent stem cells. Nat Protoc (2008) 4.85
In Support of a Patient-Driven Initiative and Petition to Lower the High Price of Cancer Drugs. Mayo Clin Proc (2015) 4.70
Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regeneration. Cell (2009) 4.69
The Lin28/let-7 axis regulates glucose metabolism. Cell (2011) 4.65
Derivation of embryonic germ cells and male gametes from embryonic stem cells. Nature (2003) 4.56
Correction of a genetic defect by nuclear transplantation and combined cell and gene therapy. Cell (2002) 4.56
Rapid chemotherapy-induced acute endothelial progenitor cell mobilization: implications for antiangiogenic drugs as chemosensitizing agents. Cancer Cell (2008) 4.51
Determinants of microRNA processing inhibition by the developmentally regulated RNA-binding protein Lin28. J Biol Chem (2008) 4.40
Derivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations. Cell (2010) 4.32
Chromatin-modifying enzymes as modulators of reprogramming. Nature (2012) 4.22
Bone-marrow adipocytes as negative regulators of the haematopoietic microenvironment. Nature (2009) 4.14
Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage. Nat Biotechnol (2011) 3.97
Centriolin anchoring of exocyst and SNARE complexes at the midbody is required for secretory-vesicle-mediated abscission. Cell (2005) 3.93
Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1. Nature (2009) 3.93
Genome-wide chromatin state transitions associated with developmental and environmental cues. Cell (2013) 3.83
Relative and absolute quantification of postsynaptic density proteome isolated from rat forebrain and cerebellum. Mol Cell Proteomics (2006) 3.56
Randomized trial using gonadotropin-releasing hormone agonist triptorelin for the preservation of ovarian function during (neo)adjuvant chemotherapy for breast cancer. J Clin Oncol (2012) 3.51
Targeting Bcr-Abl by combining allosteric with ATP-binding-site inhibitors. Nature (2010) 3.39
Lin28: A microRNA regulator with a macro role. Cell (2010) 3.39
Generation of functional human hepatic endoderm from human induced pluripotent stem cells. Hepatology (2010) 3.36
ESCRT-III dysfunction causes autophagosome accumulation and neurodegeneration. Curr Biol (2007) 3.27
Donor cell type can influence the epigenome and differentiation potential of human induced pluripotent stem cells. Nat Biotechnol (2011) 3.25
Activation of tyrosine kinases by mutation of the gatekeeper threonine. Nat Struct Mol Biol (2008) 3.18
MicroRNA-9 coordinates proliferation and migration of human embryonic stem cell-derived neural progenitors. Cell Stem Cell (2010) 3.18
Soy isoflavones in the prevention of menopausal bone loss and menopausal symptoms: a randomized, double-blind trial. Arch Intern Med (2011) 3.11
Differential modeling of fragile X syndrome by human embryonic stem cells and induced pluripotent stem cells. Cell Stem Cell (2010) 3.08
Lin28 enhances tissue repair by reprogramming cellular metabolism. Cell (2013) 3.08
Broader implications of defining standards for the pluripotency of iPSCs. Cell Stem Cell (2009) 3.03
Autocrine TGF-beta and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts. Proc Natl Acad Sci U S A (2010) 3.03
Biomechanical forces promote embryonic haematopoiesis. Nature (2009) 2.99
Metabolic regulation of protein N-alpha-acetylation by Bcl-xL promotes cell survival. Cell (2011) 2.98
Influence of threonine metabolism on S-adenosylmethionine and histone methylation. Science (2012) 2.98
Reprogramming of T cells from human peripheral blood. Cell Stem Cell (2010) 2.93
A role for Lin28 in primordial germ-cell development and germ-cell malignancy. Nature (2009) 2.88
Transplantation of adult mouse iPS cell-derived photoreceptor precursors restores retinal structure and function in degenerative mice. PLoS One (2011) 2.86
A genome-wide association study identifies two new lung cancer susceptibility loci at 13q12.12 and 22q12.2 in Han Chinese. Nat Genet (2011) 2.85
Stage-specific signaling through TGFβ family members and WNT regulates patterning and pancreatic specification of human pluripotent stem cells. Development (2011) 2.82
Comparative impact of trastuzumab and cyclophosphamide on HER-2-positive human breast cancer xenografts. Clin Cancer Res (2009) 2.79
A robust approach to identifying tissue-specific gene expression regulatory variants using personalized human induced pluripotent stem cells. PLoS Genet (2009) 2.78
High-efficiency RNA interference in human embryonic stem cells. Stem Cells (2005) 2.76
Loss of centrosome integrity induces p38-p53-p21-dependent G1-S arrest. Nat Cell Biol (2007) 2.76
Lin28a transgenic mice manifest size and puberty phenotypes identified in human genetic association studies. Nat Genet (2010) 2.72
New ISSCR guidelines underscore major principles for responsible translational stem cell research. Cell Stem Cell (2008) 2.61
Functional evidence that the self-renewal gene NANOG regulates human tumor development. Stem Cells (2009) 2.59
Induced pluripotent stem cells--opportunities for disease modelling and drug discovery. Nat Rev Drug Discov (2011) 2.58
Teratoma formation assays with human embryonic stem cells: a rationale for one type of human-animal chimera. Cell Stem Cell (2007) 2.56
Lineage regulators direct BMP and Wnt pathways to cell-specific programs during differentiation and regeneration. Cell (2011) 2.53
A novel human protein of the maternal centriole is required for the final stages of cytokinesis and entry into S phase. J Cell Biol (2003) 2.51
Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia. Nat Med (2010) 2.50
Mouse models of advanced spontaneous metastasis for experimental therapeutics. Nat Rev Cancer (2011) 2.42
LIF/STAT3 signaling fails to maintain self-renewal of human embryonic stem cells. Stem Cells (2004) 2.37
Telomere elongation in induced pluripotent stem cells from dyskeratosis congenita patients. Nature (2010) 2.36
Anticancer therapies combining antiangiogenic and tumor cell cytotoxic effects reduce the tumor stem-like cell fraction in glioma xenograft tumors. Cancer Res (2007) 2.35
Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells. Nature (2012) 2.32
Embryonic stem cell-derived hematopoietic stem cells. Proc Natl Acad Sci U S A (2005) 2.28
Lin28: primal regulator of growth and metabolism in stem cells. Cell Stem Cell (2013) 2.27
Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia. Nat Genet (2012) 2.26
Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons. Acta Neuropathol (2013) 2.26
BMP and Wnt specify hematopoietic fate by activation of the Cdx-Hox pathway. Cell Stem Cell (2008) 2.17
cdx4 mutants fail to specify blood progenitors and can be rescued by multiple hox genes. Nature (2003) 2.16
Recombination signatures distinguish embryonic stem cells derived by parthenogenesis and somatic cell nuclear transfer. Cell Stem Cell (2007) 2.14
Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability. Proc Natl Acad Sci U S A (2012) 2.14
The deubiquitinating enzyme ataxin-3, a polyglutamine disease protein, edits Lys63 linkages in mixed linkage ubiquitin chains. J Biol Chem (2008) 2.09
Site-specific ubiquitination exposes a linear motif to promote interferon-alpha receptor endocytosis. J Cell Biol (2007) 2.07
Overcoming reprogramming resistance of Fanconi anemia cells. Blood (2012) 2.07
Polycomb repressive complex 2 regulates normal development of the mouse heart. Circ Res (2011) 2.05
Stem cell metabolism in tissue development and aging. Development (2013) 2.01
Development of a preclinical model of spontaneous human melanoma central nervous system metastasis. Cancer Res (2008) 1.99
The transcriptional landscape of hematopoietic stem cell ontogeny. Cell Stem Cell (2012) 1.96