Published in Nat Cell Biol on December 14, 2008
Regulation mechanisms and signaling pathways of autophagy. Annu Rev Genet (2009) 14.06
Selective autophagy mediated by autophagic adapter proteins. Autophagy (2011) 6.88
Selective autophagy: ubiquitin-mediated recognition and beyond. Nat Cell Biol (2010) 3.74
Midbody accumulation through evasion of autophagy contributes to cellular reprogramming and tumorigenicity. Nat Cell Biol (2011) 2.65
Molecular control of animal cell cytokinesis. Nat Cell Biol (2012) 2.45
Ubiquitin accumulation in autophagy-deficient mice is dependent on the Nrf2-mediated stress response pathway: a potential role for protein aggregation in autophagic substrate selection. J Cell Biol (2010) 2.32
Ubiquitination and selective autophagy. Cell Death Differ (2012) 2.12
p62: a versatile multitasker takes on cancer. Trends Biochem Sci (2012) 1.93
p62 and NDP52 proteins target intracytosolic Shigella and Listeria to different autophagy pathways. J Biol Chem (2011) 1.82
Conserved role for autophagy in Rho1-mediated cortical remodeling and blood cell recruitment. Proc Natl Acad Sci U S A (2010) 1.71
Aggrephagy: selective disposal of protein aggregates by macroautophagy. Int J Cell Biol (2012) 1.52
Receptor protein complexes are in control of autophagy. Autophagy (2012) 1.49
Identification of autophagosome-associated proteins and regulators by quantitative proteomic analysis and genetic screens. Mol Cell Proteomics (2012) 1.38
Of the atypical PKCs, Par-4 and p62: recent understandings of the biology and pathology of a PB1-dominated complex. Cell Death Differ (2009) 1.35
Proliferating versus differentiating stem and cancer cells exhibit distinct midbody-release behaviour. Nat Commun (2011) 1.26
Reticulophagy and ribophagy: regulated degradation of protein production factories. Int J Cell Biol (2012) 1.16
Autophagy and cell growth--the yin and yang of nutrient responses. J Cell Sci (2012) 1.14
Autophagy: more than a nonselective pathway. Int J Cell Biol (2012) 1.13
The elimination of accumulated and aggregated proteins: a role for aggrephagy in neurodegeneration. Neurobiol Dis (2010) 1.12
Endocytic transport and cytokinesis: from regulation of the cytoskeleton to midbody inheritance. Trends Cell Biol (2013) 1.11
NBR1 enables autophagy-dependent focal adhesion turnover. J Cell Biol (2016) 1.05
Potential function for the Huntingtin protein as a scaffold for selective autophagy. Proc Natl Acad Sci U S A (2014) 1.05
Crystal structure of the ubiquitin-associated (UBA) domain of p62 and its interaction with ubiquitin. J Biol Chem (2011) 1.04
Proteotoxic stress induces phosphorylation of p62/SQSTM1 by ULK1 to regulate selective autophagic clearance of protein aggregates. PLoS Genet (2015) 1.04
Internalized gap junctions are degraded by autophagy. Autophagy (2012) 1.04
Proteins and mechanisms regulating gap-junction assembly, internalization, and degradation. Physiology (Bethesda) (2013) 1.03
The role of ALFY in selective autophagy. Cell Death Differ (2012) 1.00
Cytokinesis in animal cells. Cold Spring Harb Perspect Biol (2015) 0.99
Macrophage migration inhibitory factor plays a permissive role in the maintenance of cardiac contractile function under starvation through regulation of autophagy. Cardiovasc Res (2013) 0.98
Resurrecting remnants: the lives of post-mitotic midbodies. Trends Cell Biol (2012) 0.98
Apoptotic regulators promote cytokinetic midbody degradation in C. elegans. J Cell Biol (2012) 0.97
Autophagy plays a critical role in the degradation of active RHOA, the control of cell cytokinesis, and genomic stability. Cancer Res (2013) 0.97
Role of p62/SQSTM1 in liver physiology and pathogenesis. Exp Biol Med (Maywood) (2013) 0.96
Incisive imaging and computation for cellular mysteries: lessons from abscission. Cell (2013) 0.95
Accumulation of p62 in degenerated spinal cord under chronic mechanical compression: functional analysis of p62 and autophagy in hypoxic neuronal cells. Autophagy (2011) 0.93
Autophagy in DNA damage response. Int J Mol Sci (2015) 0.93
MiCroKit 3.0: an integrated database of midbody, centrosome and kinetochore. Nucleic Acids Res (2009) 0.92
Degradation of connexins and gap junctions. FEBS Lett (2014) 0.88
Macrophage migration inhibitory factor deficiency augments doxorubicin-induced cardiomyopathy. J Am Heart Assoc (2013) 0.88
ARF6 GTPase protects the post-mitotic midbody from 14-3-3-mediated disintegration. EMBO J (2012) 0.87
Receptor proteins in selective autophagy. Int J Cell Biol (2012) 0.87
The centrosome and asymmetric cell division. Prion (2009) 0.86
Mechanisms of Selective Autophagy in Normal Physiology and Cancer. J Mol Biol (2016) 0.85
Mechanistic insights into selective autophagy pathways: lessons from yeast. Nat Rev Mol Cell Biol (2016) 0.85
Degradation of endocytosed gap junctions by autophagosomal and endo-/lysosomal pathways: a perspective. J Membr Biol (2012) 0.85
Midbody: from cellular junk to regulator of cell polarity and cell fate. Curr Opin Cell Biol (2015) 0.84
Mitochondrial autophagy involving renal injury and aging is modulated by caloric intake in aged rat kidneys. PLoS One (2013) 0.82
Alfy-dependent elimination of aggregated proteins by macroautophagy: can there be too much of a good thing? Autophagy (2011) 0.80
IQGAP1 is associated with nuclear envelope reformation and completion of abscission. Cell Cycle (2015) 0.79
Novel role for the midbody in primary ciliogenesis by polarized epithelial cells. J Cell Biol (2016) 0.79
Autophagy and the Cell Cycle: A Complex Landscape. Front Oncol (2017) 0.77
Akt2 knockout alleviates prolonged caloric restriction-induced change in cardiac contractile function through regulation of autophagy. J Mol Cell Cardiol (2013) 0.77
A function for the midbody remnant in embryonic patterning. Commun Integr Biol (2014) 0.76
Autophagic degradation of peroxisomes in mammals. Biochem Soc Trans (2016) 0.76
Foci of cyclin A2 interact with actin and RhoA in mitosis. Sci Rep (2016) 0.75
TRIM17 contributes to autophagy of midbodies while actively sparing other targets from degradation. J Cell Sci (2016) 0.75
Autophagic flux is highly active in early mitosis and differentially regulated throughout the cell cycle. Oncotarget (2016) 0.75
C. elegans midbodies are released, phagocytosed and undergo LC3-dependent degradation independent of macroautophagy. J Cell Sci (2016) 0.75
Routes and machinery of primary cilium biogenesis. Cell Mol Life Sci (2017) 0.75
Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature (1999) 23.62
p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy. J Biol Chem (2007) 21.73
Development by self-digestion: molecular mechanisms and biological functions of autophagy. Dev Cell (2004) 21.68
Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy. Cell (2005) 21.01
A ubiquitin-like system mediates protein lipidation. Nature (2000) 10.61
3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes. Proc Natl Acad Sci U S A (1982) 8.71
Vacuolar import of proteins and organelles from the cytoplasm. Annu Rev Cell Dev Biol (1999) 7.75
Autophagy suppresses tumor progression by limiting chromosomal instability. Genes Dev (2007) 7.41
Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-beta, and Bcl-2. Mol Cell (2007) 7.09
Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis. Genes Dev (2007) 6.35
Central spindle assembly and cytokinesis require a kinesin-like protein/RhoGAP complex with microtubule bundling activity. Dev Cell (2002) 5.52
Role for Rab7 in maturation of late autophagic vacuoles. J Cell Sci (2004) 5.19
Animal cytokinesis: from parts list to mechanisms. Annu Rev Biochem (2006) 4.23
Centriolin anchoring of exocyst and SNARE complexes at the midbody is required for secretory-vesicle-mediated abscission. Cell (2005) 3.93
The apoptosis/autophagy paradox: autophagic vacuolization before apoptotic death. J Cell Sci (2005) 3.93
ROS, mitochondria and the regulation of autophagy. Trends Cell Biol (2007) 3.73
A block of autophagy in lysosomal storage disorders. Hum Mol Genet (2007) 3.28
Sorting, recognition and activation of the misfolded protein degradation pathways through macroautophagy and the proteasome. Autophagy (2007) 2.59
Final stages of cytokinesis and midbody ring formation are controlled by BRUCE. Cell (2008) 2.02
Inhibition of autophagy in mitotic animal cells. Traffic (2002) 1.81
Dual role of BRUCE as an antiapoptotic IAP and a chimeric E2/E3 ubiquitin ligase. Mol Cell (2004) 1.73
Storage solutions: treating lysosomal disorders of the brain. Nat Rev Neurosci (2005) 1.65
Autophagy, mitochondria and cell death in lysosomal storage diseases. Autophagy (2007) 1.55
Cell cycle-dependent induction of autophagy, mitophagy and reticulophagy. Cell Cycle (2007) 1.46
Dynamic regulation of ubiquitylation and deubiquitylation at the central spindle during cytokinesis. J Cell Sci (2008) 1.05
alpha-L-iduronidase premature stop codons and potential read-through in mucopolysaccharidosis type I patients. J Mol Biol (2004) 0.97
Biosynthesis of lysosomal proteinases in health and disease. Biol Chem (2002) 0.86
RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO. Nature (2002) 14.63
PCNA, the maestro of the replication fork. Cell (2007) 10.43
A series of ubiquitin binding factors connects CDC48/p97 to substrate multiubiquitylation and proteasomal targeting. Cell (2005) 4.97
SUMO-modified PCNA recruits Srs2 to prevent recombination during S phase. Nature (2005) 4.88
Principles of ubiquitin and SUMO modifications in DNA repair. Nature (2009) 4.10
Role of the ubiquitin-selective CDC48(UFD1/NPL4 )chaperone (segregase) in ERAD of OLE1 and other substrates. EMBO J (2002) 2.74
The Smc5-Smc6 complex and SUMO modification of Rad52 regulates recombinational repair at the ribosomal gene locus. Nat Cell Biol (2007) 2.56
The RAD6 DNA damage tolerance pathway operates uncoupled from the replication fork and is functional beyond S phase. Cell (2010) 2.46
A role for PCNA ubiquitination in immunoglobulin hypermutation. PLoS Biol (2006) 2.43
Functional division of substrate processing cofactors of the ubiquitin-selective Cdc48 chaperone. Mol Cell (2006) 2.41
Protein group modification and synergy in the SUMO pathway as exemplified in DNA repair. Cell (2012) 2.36
Chromosome-wide Rad51 spreading and SUMO-H2A.Z-dependent chromosome fixation in response to a persistent DNA double-strand break. Mol Cell (2009) 2.15
Proteasome-mediated protein processing by bidirectional degradation initiated from an internal site. Nat Struct Mol Biol (2006) 2.09
Final stages of cytokinesis and midbody ring formation are controlled by BRUCE. Cell (2008) 2.02
PCNA controls establishment of sister chromatid cohesion during S phase. Mol Cell (2006) 1.97
Deadly encounter: ubiquitin meets apoptosis. Nat Rev Mol Cell Biol (2002) 1.89
Control of Rad52 recombination activity by double-strand break-induced SUMO modification. Nat Cell Biol (2006) 1.84
Dual role of BRUCE as an antiapoptotic IAP and a chimeric E2/E3 ubiquitin ligase. Mol Cell (2004) 1.73
Monitoring homology search during DNA double-strand break repair in vivo. Mol Cell (2013) 1.69
SUMO modification of the ubiquitin-conjugating enzyme E2-25K. Nat Struct Mol Biol (2005) 1.58
Noncanonical role of the 9-1-1 clamp in the error-free DNA damage tolerance pathway. Mol Cell (2012) 1.27
Taking a bite: proteasomal protein processing. Nat Cell Biol (2002) 1.26
Role of Cdc48/p97 as a SUMO-targeted segregase curbing Rad51-Rad52 interaction. Nat Cell Biol (2013) 1.20
Productive RUPture: activation of transcription factors by proteasomal processing. Biochim Biophys Acta (2004) 1.19
Role of the ubiquitin-like protein Urm1 as a noncanonical lysine-directed protein modifier. Proc Natl Acad Sci U S A (2011) 1.16
Elg1, an alternative subunit of the RFC clamp loader, preferentially interacts with SUMOylated PCNA. EMBO J (2010) 1.12
Role of the ubiquitin-like protein Hub1 in splice-site usage and alternative splicing. Nature (2011) 1.07
BRUCE, a giant E2/E3 ubiquitin ligase and inhibitor of apoptosis protein of the trans-Golgi network, is required for normal placenta development and mouse survival. Mol Cell Biol (2004) 1.03
DNA bending facilitates the error-free DNA damage tolerance pathway and upholds genome integrity. EMBO J (2014) 1.00
Synaptonemal complex formation and meiotic checkpoint signaling are linked to the lateral element protein Red1. Proc Natl Acad Sci U S A (2010) 1.00
The ubiquitin-like protein HUB1 forms SDS-resistant complexes with cellular proteins in the absence of ATP. EMBO Rep (2003) 0.99
Prolyl isomerase Pin1 acts as a switch to control the degree of substrate ubiquitylation. Nat Cell Biol (2009) 0.99
SnapShot: The SUMO system. Cell (2010) 0.91
SM-protein-controlled ER-associated degradation discriminates between different SNAREs. EMBO Rep (2007) 0.87
9-1-1: PCNA's specialized cousin. Trends Biochem Sci (2011) 0.86
Identification of SUMO-protein conjugates. Methods Enzymol (2005) 0.81
Pin1, a novel switch in the ubiquitin pathway. Cell Cycle (2009) 0.81
γH2AX spreading linked to homology search. Cell Cycle (2013) 0.79
A new class of ubiquitin-Atg8 receptors involved in selective autophagy and polyQ protein clearance. Autophagy (2014) 0.78
The ubiquitin system in health and disease. Preface. Ernst Schering Found Symp Proc (2008) 0.76
Varshavsky's contributions. Science (2004) 0.75