Published in DNA Repair (Amst) on July 11, 2006
Hematopoietic stem cell quiescence promotes error-prone DNA repair and mutagenesis. Cell Stem Cell (2010) 4.11
Inhibition of activated pericentromeric SINE/Alu repeat transcription in senescent human adult stem cells reinstates self-renewal. Cell Cycle (2011) 3.11
Origin of chromosomal translocations in lymphoid cancer. Cell (2010) 2.94
RAD18 transmits DNA damage signalling to elicit homologous recombination repair. Nat Cell Biol (2009) 2.67
Oxidative stress resistance in Deinococcus radiodurans. Microbiol Mol Biol Rev (2011) 2.43
RAP80-directed tuning of BRCA1 homologous recombination function at ionizing radiation-induced nuclear foci. Genes Dev (2011) 2.00
Plant mitochondrial recombination surveillance requires unusual RecA and MutS homologs. Plant Cell (2007) 1.93
Manifestations and mechanisms of stem cell aging. J Cell Biol (2011) 1.93
Generation of a nicking enzyme that stimulates site-specific gene conversion from the I-AniI LAGLIDADG homing endonuclease. Proc Natl Acad Sci U S A (2009) 1.79
The role of mechanistic factors in promoting chromosomal translocations found in lymphoid and other cancers. Adv Immunol (2010) 1.77
More forks on the road to replication stress recovery. J Mol Cell Biol (2011) 1.64
SOSS complexes participate in the maintenance of genomic stability. Mol Cell (2009) 1.63
Telomere dysfunction and chromosome instability. Mutat Res (2011) 1.51
Aberrant double-strand break repair resulting in half crossovers in mutants defective for Rad51 or the DNA polymerase delta complex. Mol Cell Biol (2009) 1.47
The ERCC1/XPF endonuclease is required for efficient single-strand annealing and gene conversion in mammalian cells. Nucleic Acids Res (2007) 1.45
Chromothripsis: chromosomes in crisis. Dev Cell (2012) 1.40
Alu elements mediate MYB gene tandem duplication in human T-ALL. J Exp Med (2007) 1.37
A mobile threat to genome stability: The impact of non-LTR retrotransposons upon the human genome. Semin Cancer Biol (2010) 1.34
Aberrantly resolved RAG-mediated DNA breaks in Atm-deficient lymphocytes target chromosomal breakpoints in cis. Proc Natl Acad Sci U S A (2009) 1.25
Homology-directed repair of DNA nicks via pathways distinct from canonical double-strand break repair. Proc Natl Acad Sci U S A (2014) 1.21
Multiple-pathway analysis of double-strand break repair mutations in Drosophila. PLoS Genet (2007) 1.20
XRCC2 and XRCC3 regulate the balance between short- and long-tract gene conversions between sister chromatids. Mol Cell Biol (2009) 1.19
Recognition of DNA double strand breaks by the BRCA1 tumor suppressor network. Chromosoma (2008) 1.18
Quantification of random mutations in the mitochondrial genome. Methods (2008) 1.14
Chromatin structure regulates gene conversion. PLoS Biol (2007) 1.12
Multipotent hematopoietic cells susceptible to alternative double-strand break repair pathways that promote genome rearrangements. Genes Dev (2007) 1.10
Quality control of DNA break metabolism: in the 'end', it's a good thing. EMBO J (2008) 1.08
Mechanisms of leukemia translocations. Curr Opin Hematol (2008) 1.06
Response of heterogeneous ribonuclear proteins (hnRNP) to ionising radiation and their involvement in DNA damage repair. Int J Radiat Biol (2009) 1.05
Defective DNA double-strand break repair underlies enhanced tumorigenesis and chromosomal instability in p27-deficient mice with growth factor-induced oligodendrogliomas. Oncogene (2010) 1.02
ATM limits incorrect end utilization during non-homologous end joining of multiple chromosome breaks. PLoS Genet (2010) 0.99
Further delineation of nonhomologous-based recombination and evidence for subtelomeric segmental duplications in 1p36 rearrangements. Hum Genet (2009) 0.98
Interchromosomal crossover in human cells is associated with long gene conversion tracts. Mol Cell Biol (2007) 0.98
hSWS1·SWSAP1 is an evolutionarily conserved complex required for efficient homologous recombination repair. J Biol Chem (2011) 0.97
PARP1 is required for chromosomal translocations. Blood (2013) 0.96
Tyrosine phosphorylation enhances RAD52-mediated annealing by modulating its DNA binding. EMBO J (2011) 0.94
Transposable elements and the dynamic somatic genome. Genome Biol (2007) 0.93
Recombination activator function of the novel RAD51- and RAD51B-binding protein, human EVL. J Biol Chem (2009) 0.93
Recombination at DNA replication fork barriers is not universal and is differentially regulated by Swi1. Proc Natl Acad Sci U S A (2009) 0.93
Functional interplay between the 53BP1-ortholog Rad9 and the Mre11 complex regulates resection, end-tethering and repair of a double-strand break. PLoS Genet (2015) 0.93
Noncanonical views of homology-directed DNA repair. Genes Dev (2016) 0.92
DNA-PK phosphorylation of RPA32 Ser4/Ser8 regulates replication stress checkpoint activation, fork restart, homologous recombination and mitotic catastrophe. DNA Repair (Amst) (2014) 0.92
Mismatch repair during homologous and homeologous recombination. Cold Spring Harb Perspect Biol (2015) 0.92
Chronic oxidative DNA damage due to DNA repair defects causes chromosomal instability in Saccharomyces cerevisiae. Mol Cell Biol (2008) 0.92
Induction of chromosomal translocations in mouse and human cells using site-specific endonucleases. J Natl Cancer Inst Monogr (2008) 0.91
DNA double-strand break - induced pro-survival signaling. Radiother Oncol (2011) 0.90
Different aneuploidies arise from the same bridge-induced chromosomal translocation event in Saccharomyces cerevisiae. Genetics (2010) 0.87
Double-strand break repair by interchromosomal recombination: an in vivo repair mechanism utilized by multiple somatic tissues in mammals. PLoS One (2013) 0.85
RAD59 and RAD1 cooperate in translocation formation by single-strand annealing in Saccharomyces cerevisiae. Curr Genet (2009) 0.84
Prospective tracing of MLL-FRYL clone with low MEIS1 expression from emergence during neuroblastoma treatment to diagnosis of myelodysplastic syndrome. Blood (2008) 0.84
Towards a new era in medicine: therapeutic genome editing. Genome Biol (2015) 0.83
Etoposide sensitivity does not predict MLL rearrangements or risk of therapy-related acute myeloid leukemia. Clin Pharmacol Ther (2008) 0.82
Faithful after break-up: suppression of chromosomal translocations. Cell Mol Life Sci (2009) 0.82
Msh2 blocks an alternative mechanism for non-homologous tail removal during single-strand annealing in Saccharomyces cerevisiae. PLoS One (2009) 0.82
Post-translational modifications of proliferating cell nuclear antigen: A key signal integrator for DNA damage response (Review). Oncol Lett (2014) 0.82
Generation and repair of AID-initiated DNA lesions in B lymphocytes. Front Med (2014) 0.81
Heavy Metal Exposure Influences Double Strand Break DNA Repair Outcomes. PLoS One (2016) 0.80
Assaying break and nick-induced homologous recombination in mammalian cells using the DR-GFP reporter and Cas9 nucleases. Methods Enzymol (2014) 0.80
DNA damage response, redox status and hematopoiesis. Blood Cells Mol Dis (2013) 0.80
Distinct genetic control of homologous recombination repair of Cas9-induced double-strand breaks, nicks and paired nicks. Nucleic Acids Res (2016) 0.79
Deep Imaging: the next frontier in microscopy. Histochem Cell Biol (2014) 0.79
Altering Genomic Integrity: Heavy Metal Exposure Promotes Transposable Element-Mediated Damage. Biol Trace Elem Res (2015) 0.78
The Role of the Core Non-Homologous End Joining Factors in Carcinogenesis and Cancer. Cancers (Basel) (2017) 0.78
Rad59 regulates association of Rad52 with DNA double-strand breaks. Microbiologyopen (2012) 0.78
Novel regenerative peptide TP508 mitigates radiation-induced gastrointestinal damage by activating stem cells and preserving crypt integrity. Lab Invest (2015) 0.78
Genotoxic therapy stimulates error-prone DNA repair in dormant hepatocellular cancer stem cells. Exp Ther Med (2012) 0.77
Mechanisms leading to nonrandom, nonhomologous chromosomal translocations in leukemia. Semin Cancer Biol (2006) 0.77
Simian virus 40 strains with novel properties generated by replacing the viral enhancer with synthetic oligonucleotides. J Virol (2012) 0.77
Roles of retrotransposons in benign and malignant hematologic disease. Cellscience (2009) 0.76
Interference in DNA replication can cause mitotic chromosomal breakage unassociated with double-strand breaks. PLoS One (2013) 0.76
Drugging the Cancers Addicted to DNA Repair. J Natl Cancer Inst (2017) 0.75
Potential role of oxidative stress-induced apoptosis in mediating chromosomal rearrangements in nasopharyngeal carcinoma. Cell Biosci (2016) 0.75
Regulation of pairing between broken DNA-containing chromatin regions by Ku80, DNA-PKcs, ATM, and 53BP1. Sci Rep (2017) 0.75
From the shards of a shattered genome, diversity. Proc Natl Acad Sci U S A (2008) 0.75
Gene Editing of Human Hematopoietic Stem and Progenitor Cells: Promise and Potential Hurdles. Hum Gene Ther (2016) 0.75
Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2. Mol Cell (2006) 7.33
Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis. Nat Rev Mol Cell Biol (2010) 5.35
Double-strand break repair-independent role for BRCA2 in blocking stalled replication fork degradation by MRE11. Cell (2011) 4.41
Positional stability of single double-strand breaks in mammalian cells. Nat Cell Biol (2007) 4.35
RECQL5/Recql5 helicase regulates homologous recombination and suppresses tumor formation via disruption of Rad51 presynaptic filaments. Genes Dev (2007) 4.16
Genetic steps of mammalian homologous repair with distinct mutagenic consequences. Mol Cell Biol (2004) 3.96
Human Fanconi anemia monoubiquitination pathway promotes homologous DNA repair. Proc Natl Acad Sci U S A (2005) 3.93
CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair. Nature (2005) 3.90
A distinct replication fork protection pathway connects Fanconi anemia tumor suppressors to RAD51-BRCA1/2. Cancer Cell (2012) 3.26
A hierarchical combination of factors shapes the genome-wide topography of yeast meiotic recombination initiation. Cell (2011) 3.08
A forward chemical genetic screen reveals an inhibitor of the Mre11-Rad50-Nbs1 complex. Nat Chem Biol (2008) 3.07
Evidence for replicative repair of DNA double-strand breaks leading to oncogenic translocation and gene amplification. J Exp Med (2002) 2.86
Chromosomal translocations induced at specified loci in human stem cells. Proc Natl Acad Sci U S A (2009) 2.73
Alternative end-joining is suppressed by the canonical NHEJ component Xrcc4-ligase IV during chromosomal translocation formation. Nat Struct Mol Biol (2010) 2.65
Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway. PLoS Genet (2012) 2.63
Distinct properties of the XY pseudoautosomal region crucial for male meiosis. Science (2011) 2.43
DNA ligase III promotes alternative nonhomologous end-joining during chromosomal translocation formation. PLoS Genet (2011) 2.22
Assaying double-strand break repair pathway choice in mammalian cells using a targeted endonuclease or the RAG recombinase. Methods Enzymol (2006) 2.21
BRCA1 tumor suppression depends on BRCT phosphoprotein binding, but not its E3 ligase activity. Science (2011) 2.17
Mouse HORMAD1 and HORMAD2, two conserved meiotic chromosomal proteins, are depleted from synapsed chromosome axes with the help of TRIP13 AAA-ATPase. PLoS Genet (2009) 2.15
Androgen receptor signaling regulates DNA repair in prostate cancers. Cancer Discov (2013) 2.15
Surveillance of different recombination defects in mouse spermatocytes yields distinct responses despite elimination at an identical developmental stage. Mol Cell Biol (2005) 2.13
Collaboration and competition between DNA double-strand break repair pathways. FEBS Lett (2010) 2.11
Suppression of the DNA repair defects of BRCA2-deficient cells with heterologous protein fusions. Proc Natl Acad Sci U S A (2006) 2.10
Formation of NHEJ-derived reciprocal chromosomal translocations does not require Ku70. Nat Cell Biol (2007) 2.10
Interplay between human DNA repair proteins at a unique double-strand break in vivo. EMBO J (2006) 2.09
Involvement of mammalian Mus81 in genome integrity and tumor suppression. Science (2004) 2.03
Distinct DNA-damage-dependent and -independent responses drive the loss of oocytes in recombination-defective mouse mutants. Proc Natl Acad Sci U S A (2005) 2.03
Hypoxia-induced down-regulation of BRCA1 expression by E2Fs. Cancer Res (2005) 2.02
ATP hydrolysis by mammalian RAD51 has a key role during homology-directed DNA repair. J Biol Chem (2002) 1.97
E3 ligase activity of BRCA1 is not essential for mammalian cell viability or homology-directed repair of double-strand DNA breaks. Proc Natl Acad Sci U S A (2008) 1.97
Rad51 overexpression promotes alternative double-strand break repair pathways and genome instability. Oncogene (2004) 1.95
Neither DNA hypomethylation nor changes in the kinetics of erythroid differentiation explain 5-azacytidine's ability to induce human fetal hemoglobin. Blood (2007) 1.92
An essential role for CtIP in chromosomal translocation formation through an alternative end-joining pathway. Nat Struct Mol Biol (2010) 1.92
Chromosomal translocation mechanisms at intronic alu elements in mammalian cells. Mol Cell (2005) 1.84
Crucial role for DNA ligase III in mitochondria but not in Xrcc1-dependent repair. Nature (2011) 1.80
Ablation of PARP-1 does not interfere with the repair of DNA double-strand breaks, but compromises the reactivation of stalled replication forks. Oncogene (2004) 1.79
A model of oncogenic rearrangements: differences between chromosomal translocation mechanisms and simple double-strand break repair. Blood (2005) 1.78
Collaboration of homologous recombination and nonhomologous end-joining factors for the survival and integrity of mice and cells. Genes Dev (2004) 1.77
Homeostatic control of recombination is implemented progressively in mouse meiosis. Nat Cell Biol (2012) 1.73
An xrcc4 defect or Wortmannin stimulates homologous recombination specifically induced by double-strand breaks in mammalian cells. Nucleic Acids Res (2002) 1.70
Eme1 is involved in DNA damage processing and maintenance of genomic stability in mammalian cells. EMBO J (2003) 1.68
ATM controls meiotic double-strand-break formation. Nature (2011) 1.68
The E3 ubiquitin ligase Cullin 4A regulates meiotic progression in mouse spermatogenesis. Dev Biol (2011) 1.67
Extensive loss of heterozygosity is suppressed during homologous repair of chromosomal breaks. Mol Cell Biol (2003) 1.65
ATM promotes the obligate XY crossover and both crossover control and chromosome axis integrity on autosomes. PLoS Genet (2008) 1.61
Mouse TRIP13/PCH2 is required for recombination and normal higher-order chromosome structure during meiosis. PLoS Genet (2010) 1.54
Cancer translocations in human cells induced by zinc finger and TALE nucleases. Genome Res (2013) 1.44
Numerical constraints and feedback control of double-strand breaks in mouse meiosis. Genes Dev (2013) 1.43
Meiotic homologue alignment and its quality surveillance are controlled by mouse HORMAD1. Nat Cell Biol (2011) 1.40
Measuring recombination proficiency in mouse embryonic stem cells. Methods Mol Biol (2005) 1.39
BARD1 participates with BRCA1 in homology-directed repair of chromosome breaks. Mol Cell Biol (2003) 1.34
Evolutionary conservation of meiotic DSB proteins: more than just Spo11. Genes Dev (2010) 1.33
Alternative pathways for the repair of RAG-induced DNA breaks. Mol Cell Biol (2006) 1.32
Homologous recombination deficiency leads to profound genetic instability in cells derived from Xrcc2-knockout mice. Cancer Res (2003) 1.32
Homology-directed Fanconi anemia pathway cross-link repair is dependent on DNA replication. Nat Struct Mol Biol (2011) 1.29
Double-strand break repair by homologous recombination in primary mouse somatic cells requires BRCA1 but not the ATM kinase. Proc Natl Acad Sci U S A (2013) 1.27
The Fanconi anemia group A protein modulates homologous repair of DNA double-strand breaks in mammalian cells. Carcinogenesis (2005) 1.21
Comprehensive, fine-scale dissection of homologous recombination outcomes at a hot spot in mouse meiosis. Mol Cell (2010) 1.21
DNA damage responses by human ELG1 in S phase are important to maintain genomic integrity. Cell Cycle (2009) 1.18
Developmental- and differentiation-specific patterns of human gamma- and beta-globin promoter DNA methylation. Blood (2007) 1.17
Role for the mammalian Swi5-Sfr1 complex in DNA strand break repair through homologous recombination. PLoS Genet (2010) 1.16
Variant XRCC3 implicated in cancer is functional in homology-directed repair of double-strand breaks. Oncogene (2002) 1.15
Mechanisms of recombination between diverged sequences in wild-type and BLM-deficient mouse and human cells. Mol Cell Biol (2010) 1.12
Molecular basis for enhancement of the meiotic DMC1 recombinase by RAD51 associated protein 1 (RAD51AP1). Proc Natl Acad Sci U S A (2011) 1.11
Fen-1 facilitates homologous recombination by removing divergent sequences at DNA break ends. Mol Cell Biol (2005) 1.09
Interhomolog recombination and loss of heterozygosity in wild-type and Bloom syndrome helicase (BLM)-deficient mammalian cells. Proc Natl Acad Sci U S A (2011) 1.09
Homologous recombination DNA repair genes play a critical role in reprogramming to a pluripotent state. Cell Rep (2013) 1.07
Up-regulation of AMP-activated kinase by dysfunctional cystic fibrosis transmembrane conductance regulator in cystic fibrosis airway epithelial cells mitigates excessive inflammation. J Biol Chem (2005) 1.04
Plasticity of BRCA2 function in homologous recombination: genetic interactions of the PALB2 and DNA binding domains. PLoS Genet (2011) 1.02
Loss of 53BP1 is a gain for BRCA1 mutant cells. Cancer Cell (2010) 1.01
RECQ1 plays a distinct role in cellular response to oxidative DNA damage. DNA Repair (Amst) (2012) 1.00
Mouse strains with an active H2-Ea meiotic recombination hot spot exhibit increased levels of H2-Ea-specific DNA breaks in testicular germ cells. Mol Cell Biol (2004) 0.98
Molecular cross-talk among chromosome fragility syndromes. Genes Dev (2004) 0.96
Homologous recombination assay for interstrand cross-link repair. Methods Mol Biol (2011) 0.95
Structural requirements for the BARD1 tumor suppressor in chromosomal stability and homology-directed DNA repair. J Biol Chem (2007) 0.95
Gene conversion is strongly induced in human cells by double-strand breaks and is modulated by the expression of BCL-x(L). Cancer Res (2002) 0.94
Meiotic crossover hotspots contained in haplotype block boundaries of the mouse genome. Proc Natl Acad Sci U S A (2007) 0.93
Reduced repair of DNA double-strand breaks by homologous recombination in a DNA ligase I-deficient human cell line. DNA Repair (Amst) (2005) 0.91
Induction of chromosomal translocations in mouse and human cells using site-specific endonucleases. J Natl Cancer Inst Monogr (2008) 0.91
The tricky path to recombining X and Y chromosomes in meiosis. Ann N Y Acad Sci (2012) 0.90
Development of an assay to measure mutagenic non-homologous end-joining repair activity in mammalian cells. Nucleic Acids Res (2013) 0.90
Reduced proficiency in homologous recombination underlies the high sensitivity of embryonal carcinoma testicular germ cell tumors to Cisplatin and poly (adp-ribose) polymerase inhibition. PLoS One (2012) 0.89
p21 promotes error-free replication-coupled DNA double-strand break repair. Nucleic Acids Res (2012) 0.89
Expression of arf tumor suppressor in spermatogonia facilitates meiotic progression in male germ cells. PLoS Genet (2011) 0.88
Ikaros increases normal apoptosis in adult erythroid cells. Am J Hematol (2006) 0.87
Mice deficient for the type II topoisomerase-like DNA transesterase Spo11 show normal immunoglobulin somatic hypermutation and class switching. Eur J Immunol (2002) 0.87
The transposase domain protein Metnase/SETMAR suppresses chromosomal translocations. Cancer Genet Cytogenet (2010) 0.86
Isolation of meiotic recombinants from mouse sperm. Methods Mol Biol (2011) 0.86
DNA ligase III: a spotty presence in eukaryotes, but an essential function where tested. Cell Cycle (2011) 0.86
Preaching about the converted: how meiotic gene conversion influences genomic diversity. Ann N Y Acad Sci (2012) 0.85
Rad51 presynaptic filament stabilization function of the mouse Swi5-Sfr1 heterodimeric complex. Nucleic Acids Res (2012) 0.85
Attenuating homologous recombination stimulates an AID-induced antileukemic effect. J Exp Med (2013) 0.85
Distinct effects of DNA-PKcs and Artemis inactivation on signal joint formation in vivo. Mol Immunol (2008) 0.85
Mouse BAZ1A (ACF1) is dispensable for double-strand break repair but is essential for averting improper gene expression during spermatogenesis. PLoS Genet (2013) 0.84
Developmentally regulated extended domains of DNA hypomethylation encompass highly transcribed genes of the human beta-globin locus. Exp Hematol (2009) 0.83
Complex developmental patterns of histone modifications associated with the human beta-globin switch in primary cells. Exp Hematol (2009) 0.83