Published in J Natl Cancer Inst Monogr on January 01, 2008
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Chromosomal translocation mechanisms at intronic alu elements in mammalian cells. Mol Cell (2005) 1.84
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Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2. Mol Cell (2006) 7.33
Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis. Nat Rev Mol Cell Biol (2010) 5.35
Double-strand break repair-independent role for BRCA2 in blocking stalled replication fork degradation by MRE11. Cell (2011) 4.41
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RECQL5/Recql5 helicase regulates homologous recombination and suppresses tumor formation via disruption of Rad51 presynaptic filaments. Genes Dev (2007) 4.16
Genetic steps of mammalian homologous repair with distinct mutagenic consequences. Mol Cell Biol (2004) 3.96
Human Fanconi anemia monoubiquitination pathway promotes homologous DNA repair. Proc Natl Acad Sci U S A (2005) 3.93
CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair. Nature (2005) 3.90
A distinct replication fork protection pathway connects Fanconi anemia tumor suppressors to RAD51-BRCA1/2. Cancer Cell (2012) 3.26
A hierarchical combination of factors shapes the genome-wide topography of yeast meiotic recombination initiation. Cell (2011) 3.08
A forward chemical genetic screen reveals an inhibitor of the Mre11-Rad50-Nbs1 complex. Nat Chem Biol (2008) 3.07
Evidence for replicative repair of DNA double-strand breaks leading to oncogenic translocation and gene amplification. J Exp Med (2002) 2.86
Chromosomal translocations induced at specified loci in human stem cells. Proc Natl Acad Sci U S A (2009) 2.73
Alternative end-joining is suppressed by the canonical NHEJ component Xrcc4-ligase IV during chromosomal translocation formation. Nat Struct Mol Biol (2010) 2.65
Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway. PLoS Genet (2012) 2.63
Distinct properties of the XY pseudoautosomal region crucial for male meiosis. Science (2011) 2.43
DNA ligase III promotes alternative nonhomologous end-joining during chromosomal translocation formation. PLoS Genet (2011) 2.22
Assaying double-strand break repair pathway choice in mammalian cells using a targeted endonuclease or the RAG recombinase. Methods Enzymol (2006) 2.21
BRCA1 tumor suppression depends on BRCT phosphoprotein binding, but not its E3 ligase activity. Science (2011) 2.17
Mouse HORMAD1 and HORMAD2, two conserved meiotic chromosomal proteins, are depleted from synapsed chromosome axes with the help of TRIP13 AAA-ATPase. PLoS Genet (2009) 2.15
Androgen receptor signaling regulates DNA repair in prostate cancers. Cancer Discov (2013) 2.15
Surveillance of different recombination defects in mouse spermatocytes yields distinct responses despite elimination at an identical developmental stage. Mol Cell Biol (2005) 2.13
Collaboration and competition between DNA double-strand break repair pathways. FEBS Lett (2010) 2.11
Suppression of the DNA repair defects of BRCA2-deficient cells with heterologous protein fusions. Proc Natl Acad Sci U S A (2006) 2.10
Formation of NHEJ-derived reciprocal chromosomal translocations does not require Ku70. Nat Cell Biol (2007) 2.10
Interplay between human DNA repair proteins at a unique double-strand break in vivo. EMBO J (2006) 2.09
Involvement of mammalian Mus81 in genome integrity and tumor suppression. Science (2004) 2.03
Modeling oncogenic translocations: distinct roles for double-strand break repair pathways in translocation formation in mammalian cells. DNA Repair (Amst) (2006) 2.03
Distinct DNA-damage-dependent and -independent responses drive the loss of oocytes in recombination-defective mouse mutants. Proc Natl Acad Sci U S A (2005) 2.03
Hypoxia-induced down-regulation of BRCA1 expression by E2Fs. Cancer Res (2005) 2.02
ATP hydrolysis by mammalian RAD51 has a key role during homology-directed DNA repair. J Biol Chem (2002) 1.97
E3 ligase activity of BRCA1 is not essential for mammalian cell viability or homology-directed repair of double-strand DNA breaks. Proc Natl Acad Sci U S A (2008) 1.97
Rad51 overexpression promotes alternative double-strand break repair pathways and genome instability. Oncogene (2004) 1.95
An essential role for CtIP in chromosomal translocation formation through an alternative end-joining pathway. Nat Struct Mol Biol (2010) 1.92
Chromosomal translocation mechanisms at intronic alu elements in mammalian cells. Mol Cell (2005) 1.84
Crucial role for DNA ligase III in mitochondria but not in Xrcc1-dependent repair. Nature (2011) 1.80
Ablation of PARP-1 does not interfere with the repair of DNA double-strand breaks, but compromises the reactivation of stalled replication forks. Oncogene (2004) 1.79
A model of oncogenic rearrangements: differences between chromosomal translocation mechanisms and simple double-strand break repair. Blood (2005) 1.78
Collaboration of homologous recombination and nonhomologous end-joining factors for the survival and integrity of mice and cells. Genes Dev (2004) 1.77
Homeostatic control of recombination is implemented progressively in mouse meiosis. Nat Cell Biol (2012) 1.73
An xrcc4 defect or Wortmannin stimulates homologous recombination specifically induced by double-strand breaks in mammalian cells. Nucleic Acids Res (2002) 1.70
ATM controls meiotic double-strand-break formation. Nature (2011) 1.68
Eme1 is involved in DNA damage processing and maintenance of genomic stability in mammalian cells. EMBO J (2003) 1.68
The E3 ubiquitin ligase Cullin 4A regulates meiotic progression in mouse spermatogenesis. Dev Biol (2011) 1.67
Extensive loss of heterozygosity is suppressed during homologous repair of chromosomal breaks. Mol Cell Biol (2003) 1.65
ATM promotes the obligate XY crossover and both crossover control and chromosome axis integrity on autosomes. PLoS Genet (2008) 1.61
Mouse TRIP13/PCH2 is required for recombination and normal higher-order chromosome structure during meiosis. PLoS Genet (2010) 1.54
Cancer translocations in human cells induced by zinc finger and TALE nucleases. Genome Res (2013) 1.44
Numerical constraints and feedback control of double-strand breaks in mouse meiosis. Genes Dev (2013) 1.43
Meiotic homologue alignment and its quality surveillance are controlled by mouse HORMAD1. Nat Cell Biol (2011) 1.40
Measuring recombination proficiency in mouse embryonic stem cells. Methods Mol Biol (2005) 1.39
BARD1 participates with BRCA1 in homology-directed repair of chromosome breaks. Mol Cell Biol (2003) 1.34
Evolutionary conservation of meiotic DSB proteins: more than just Spo11. Genes Dev (2010) 1.33
Homologous recombination deficiency leads to profound genetic instability in cells derived from Xrcc2-knockout mice. Cancer Res (2003) 1.32
Alternative pathways for the repair of RAG-induced DNA breaks. Mol Cell Biol (2006) 1.32
Homology-directed Fanconi anemia pathway cross-link repair is dependent on DNA replication. Nat Struct Mol Biol (2011) 1.29
Double-strand break repair by homologous recombination in primary mouse somatic cells requires BRCA1 but not the ATM kinase. Proc Natl Acad Sci U S A (2013) 1.27
Comprehensive, fine-scale dissection of homologous recombination outcomes at a hot spot in mouse meiosis. Mol Cell (2010) 1.21
The Fanconi anemia group A protein modulates homologous repair of DNA double-strand breaks in mammalian cells. Carcinogenesis (2005) 1.21
DNA damage responses by human ELG1 in S phase are important to maintain genomic integrity. Cell Cycle (2009) 1.18
Role for the mammalian Swi5-Sfr1 complex in DNA strand break repair through homologous recombination. PLoS Genet (2010) 1.16
Variant XRCC3 implicated in cancer is functional in homology-directed repair of double-strand breaks. Oncogene (2002) 1.15
Mechanisms of recombination between diverged sequences in wild-type and BLM-deficient mouse and human cells. Mol Cell Biol (2010) 1.12
Molecular basis for enhancement of the meiotic DMC1 recombinase by RAD51 associated protein 1 (RAD51AP1). Proc Natl Acad Sci U S A (2011) 1.11
Fen-1 facilitates homologous recombination by removing divergent sequences at DNA break ends. Mol Cell Biol (2005) 1.09
Interhomolog recombination and loss of heterozygosity in wild-type and Bloom syndrome helicase (BLM)-deficient mammalian cells. Proc Natl Acad Sci U S A (2011) 1.09
Homologous recombination DNA repair genes play a critical role in reprogramming to a pluripotent state. Cell Rep (2013) 1.07
Plasticity of BRCA2 function in homologous recombination: genetic interactions of the PALB2 and DNA binding domains. PLoS Genet (2011) 1.02
Loss of 53BP1 is a gain for BRCA1 mutant cells. Cancer Cell (2010) 1.01
RECQ1 plays a distinct role in cellular response to oxidative DNA damage. DNA Repair (Amst) (2012) 1.00
Mouse strains with an active H2-Ea meiotic recombination hot spot exhibit increased levels of H2-Ea-specific DNA breaks in testicular germ cells. Mol Cell Biol (2004) 0.98
Molecular cross-talk among chromosome fragility syndromes. Genes Dev (2004) 0.96
Structural requirements for the BARD1 tumor suppressor in chromosomal stability and homology-directed DNA repair. J Biol Chem (2007) 0.95
Homologous recombination assay for interstrand cross-link repair. Methods Mol Biol (2011) 0.95
Gene conversion is strongly induced in human cells by double-strand breaks and is modulated by the expression of BCL-x(L). Cancer Res (2002) 0.94
Meiotic crossover hotspots contained in haplotype block boundaries of the mouse genome. Proc Natl Acad Sci U S A (2007) 0.93
Reduced repair of DNA double-strand breaks by homologous recombination in a DNA ligase I-deficient human cell line. DNA Repair (Amst) (2005) 0.91
The tricky path to recombining X and Y chromosomes in meiosis. Ann N Y Acad Sci (2012) 0.90
Retracted Triplex-forming oligonucleotide-orthophenanthroline conjugates for efficient targeted genome modification. Proc Natl Acad Sci U S A (2008) 0.90
Development of an assay to measure mutagenic non-homologous end-joining repair activity in mammalian cells. Nucleic Acids Res (2013) 0.90
p21 promotes error-free replication-coupled DNA double-strand break repair. Nucleic Acids Res (2012) 0.89
Reduced proficiency in homologous recombination underlies the high sensitivity of embryonal carcinoma testicular germ cell tumors to Cisplatin and poly (adp-ribose) polymerase inhibition. PLoS One (2012) 0.89
Expression of arf tumor suppressor in spermatogonia facilitates meiotic progression in male germ cells. PLoS Genet (2011) 0.88
Mice deficient for the type II topoisomerase-like DNA transesterase Spo11 show normal immunoglobulin somatic hypermutation and class switching. Eur J Immunol (2002) 0.87
Isolation of meiotic recombinants from mouse sperm. Methods Mol Biol (2011) 0.86
The transposase domain protein Metnase/SETMAR suppresses chromosomal translocations. Cancer Genet Cytogenet (2010) 0.86
DNA ligase III: a spotty presence in eukaryotes, but an essential function where tested. Cell Cycle (2011) 0.86
Preaching about the converted: how meiotic gene conversion influences genomic diversity. Ann N Y Acad Sci (2012) 0.85
Rad51 presynaptic filament stabilization function of the mouse Swi5-Sfr1 heterodimeric complex. Nucleic Acids Res (2012) 0.85
Attenuating homologous recombination stimulates an AID-induced antileukemic effect. J Exp Med (2013) 0.85
Distinct effects of DNA-PKcs and Artemis inactivation on signal joint formation in vivo. Mol Immunol (2008) 0.85
Mouse BAZ1A (ACF1) is dispensable for double-strand break repair but is essential for averting improper gene expression during spermatogenesis. PLoS Genet (2013) 0.84
RAD51 can inhibit PDGF-B-induced gliomagenesis and genomic instability. Neuro Oncol (2011) 0.82
53BP1 is a haploinsufficient tumor suppressor and protects cells from radiation response in glioma. Cancer Res (2012) 0.82