Published in Genome Biol on March 17, 2011
The transient receptor potential channel TRPA1: from gene to pathophysiology. Pflugers Arch (2012) 1.63
Plasma membrane cyclic nucleotide gated calcium channels control land plant thermal sensing and acquired thermotolerance. Plant Cell (2012) 1.49
The puzzle of TRPV4 channelopathies. EMBO Rep (2013) 1.33
Transient receptor potential (TRP) channels: a clinical perspective. Br J Pharmacol (2014) 1.25
Regulation of cation balance in Saccharomyces cerevisiae. Genetics (2013) 1.25
Remodeling of calcium signaling in tumor progression. J Biomed Sci (2013) 1.19
TRPV3: time to decipher a poorly understood family member! J Physiol (2013) 1.18
Direct evidence for functional TRPV1/TRPA1 heteromers. Pflugers Arch (2014) 1.03
Fruit flies in biomedical research. Genetics (2015) 1.00
Proton-sensitive cation channels and ion exchangers in ischemic brain injury: new therapeutic targets for stroke? Prog Neurobiol (2014) 0.96
Molecular genetics and functional anomalies in a series of 248 Brugada cases with 11 mutations in the TRPM4 channel. PLoS One (2013) 0.94
Loss of interneuron LTD and attenuated pyramidal cell LTP in Trpv1 and Trpv3 KO mice. Hippocampus (2013) 0.94
Targeted silencing of TRPM7 ion channel induces replicative senescence and produces enhanced cytotoxicity with gemcitabine in pancreatic adenocarcinoma. Cancer Lett (2011) 0.93
TRPA1 mediates bladder hyperalgesia in a mouse model of cystitis. Pain (2014) 0.91
Transient receptor potential ion channels in primary sensory neurons as targets for novel analgesics. Br J Pharmacol (2014) 0.91
N-glycosylation determines the abundance of the transient receptor potential channel TRPP2. J Biol Chem (2014) 0.91
The role of endogenous molecules in modulating pain through transient receptor potential vanilloid 1 (TRPV1). J Physiol (2013) 0.90
What do we know about the transient receptor potential vanilloid 2 (TRPV2) ion channel? FEBS J (2013) 0.90
Novel endogenous N-acyl amides activate TRPV1-4 receptors, BV-2 microglia, and are regulated in brain in an acute model of inflammation. Front Cell Neurosci (2014) 0.89
Englerin A Agonizes the TRPC4/C5 Cation Channels to Inhibit Tumor Cell Line Proliferation. PLoS One (2015) 0.89
Understanding TRPV1 activation by ligands: Insights from the binding modes of capsaicin and resiniferatoxin. Proc Natl Acad Sci U S A (2015) 0.89
Macrophage function in atherosclerosis: potential roles of TRP channels. Channels (Austin) (2012) 0.89
Cellular and Developmental Biology of TRPM7 Channel-Kinase: Implicated Roles in Cancer. Cells (2014) 0.89
Role of TRP channels in the cardiovascular system. Am J Physiol Heart Circ Physiol (2014) 0.88
Mating behavior, male sensory cilia, and polycystins in Caenorhabditis elegans. Semin Cell Dev Biol (2014) 0.88
Membrane Repair: Mechanisms and Pathophysiology. Physiol Rev (2015) 0.88
Transient receptor potential channels as targets for phytochemicals. ACS Chem Neurosci (2014) 0.88
Novel regulatory mechanism in human urinary bladder: central role of transient receptor potential melastatin 4 channels in detrusor smooth muscle function. Am J Physiol Cell Physiol (2016) 0.87
Emerging role of TRP channels in cell migration: from tumor vascularization to metastasis. Front Physiol (2013) 0.87
Mutation of I696 and W697 in the TRP box of vanilloid receptor subtype I modulates allosteric channel activation. J Gen Physiol (2014) 0.87
Mechanisms underlying the analgesic effect of moxibustion on visceral pain in irritable bowel syndrome: a review. Evid Based Complement Alternat Med (2014) 0.87
Expression of Transient Receptor Potential Vanilloid (TRPV) channels in different passages of articular chondrocytes. Int J Mol Sci (2012) 0.86
TRPV1 antagonist capsazepine suppresses 4-AP-induced epileptiform activity in vitro and electrographic seizures in vivo. Exp Neurol (2013) 0.86
Monoacylglycerols activate TRPV1--a link between phospholipase C and TRPV1. PLoS One (2013) 0.86
Activation of TRPV1 channel by dietary capsaicin improves visceral fat remodeling through connexin43-mediated Ca2+ influx. Cardiovasc Diabetol (2015) 0.85
Decreased anxiety-like behavior and Gαq/11-dependent responses in the amygdala of mice lacking TRPC4 channels. J Neurosci (2014) 0.85
Permeation, regulation and control of expression of TRP channels by trace metal ions. Pflugers Arch (2014) 0.85
TRPM7 and TRPM8 Ion Channels in Pancreatic Adenocarcinoma: Potential Roles as Cancer Biomarkers and Targets. Scientifica (Cairo) (2012) 0.85
Characterization of a ligand binding site in the human transient receptor potential ankyrin 1 pore. Biophys J (2013) 0.85
Ca(2+) influx in T cells: how many ca(2+) channels? Front Immunol (2013) 0.84
Membrane trafficking in podocyte health and disease. Pediatr Nephrol (2012) 0.84
Ion channels as drug targets in central nervous system disorders. Curr Med Chem (2013) 0.84
Conduits of life's spark: a perspective on ion channel research since the birth of neuron. Neuron (2013) 0.84
Functional and evolutionary aspects of chemoreceptors. Front Cell Neurosci (2012) 0.84
The roles of G proteins in the activation of TRPC4 and TRPC5 transient receptor potential channels. Channels (Austin) (2012) 0.84
TRP channels coordinate ion signalling in astroglia. Rev Physiol Biochem Pharmacol (2014) 0.84
Dietary capsaicin prevents nonalcoholic fatty liver disease through transient receptor potential vanilloid 1-mediated peroxisome proliferator-activated receptor δ activation. Pflugers Arch (2013) 0.84
Danger- and pathogen-associated molecular patterns recognition by pattern-recognition receptors and ion channels of the transient receptor potential family triggers the inflammasome activation in immune cells and sensory neurons. J Neuroinflammation (2015) 0.83
Mutation of the melastatin-related cation channel, TRPM3, underlies inherited cataract and glaucoma. PLoS One (2014) 0.83
Nanomolar ouabain augments Ca2+ signalling in rat hippocampal neurones and glia. J Physiol (2013) 0.83
Astrocytes in the optic nerve head express putative mechanosensitive channels. Mol Vis (2015) 0.83
Transient receptor potential channels and regulation of lung endothelial permeability. Pulm Circ (2013) 0.82
Opportunistic activation of TRP receptors by endogenous lipids: exploiting lipidomics to understand TRP receptor cellular communication. Life Sci (2012) 0.82
Phospholipase C epsilon (PLCε) induced TRPC6 activation: a common but redundant mechanism in primary podocytes. J Cell Physiol (2015) 0.82
Discrete control of TRPV4 channel function in the distal nephron by protein kinases A and C. J Biol Chem (2013) 0.82
Inseparable tandem: evolution chooses ATP and Ca2+ to control life, death and cellular signalling. Philos Trans R Soc Lond B Biol Sci (2016) 0.82
Age-related changes in the distribution of transient receptor potential vanilloid 4 channel (TRPV4) in the central nervous system of rats. J Mol Histol (2014) 0.82
Natural killer cells and single nucleotide polymorphisms of specific ion channels and receptor genes in myalgic encephalomyelitis/chronic fatigue syndrome. Appl Clin Genet (2016) 0.82
Post-Translational Modifications of TRP Channels. Cells (2014) 0.81
A network perspective on unraveling the role of TRP channels in biology and disease. Pflugers Arch (2013) 0.81
Carvacrol together with TRPC1 elimination improve functional recovery after traumatic brain injury in mice. J Neurotrauma (2012) 0.81
TRIP database 2.0: a manually curated information hub for accessing TRP channel interaction network. PLoS One (2012) 0.81
Sur1-Trpm4 Cation Channel Expression in Human Cerebral Infarcts. J Neuropathol Exp Neurol (2015) 0.80
TRP channels and STIM/ORAI proteins: sensors and effectors of cancer and stroma cell migration. Br J Pharmacol (2014) 0.80
Molecular bases of multimodal regulation of a fungal transient receptor potential (TRP) channel. J Biol Chem (2013) 0.80
Different ligands of the TRPV3 cation channel cause distinct conformational changes as revealed by intrinsic tryptophan fluorescence quenching. J Biol Chem (2015) 0.78
Serotonin stimulates lateral habenula via activation of the post-synaptic serotonin 2/3 receptors and transient receptor potential channels. Neuropharmacology (2015) 0.78
Targeting TRP ion channels for itch relief. Naunyn Schmiedebergs Arch Pharmacol (2014) 0.78
Evolutionary dynamics of metazoan TRP channels. Pflugers Arch (2015) 0.78
Comparison of potato and asian citrus psyllid adult and nymph transcriptomes identified vector transcripts with potential involvement in circulative, propagative liberibacter transmission. Pathogens (2014) 0.78
Impact of intracellular ion channels on cancer development and progression. Eur Biophys J (2016) 0.78
Dissecting domain-specific evolutionary pressure profiles of transient receptor potential vanilloid subfamily members 1 to 4. PLoS One (2014) 0.77
Yeast luminometric and Xenopus oocyte electrophysiological examinations of the molecular mechanosensitivity of TRPV4. J Vis Exp (2013) 0.77
Gating modulation by heat of the polycystin transient receptor potential channel PKD2L1 (TRPP3). Pflugers Arch (2014) 0.77
Region-specific changes in the immunoreactivity of TRPV4 expression in the central nervous system of SOD1(G93A) transgenic mice as an in vivo model of amyotrophic lateral sclerosis. J Mol Histol (2012) 0.77
TRPM7, the cytoskeleton and neuronal death. Channels (Austin) (2012) 0.77
Isoform-specific modulation of the chemical sensitivity of conserved TRPA1 channel in the major honeybee ectoparasitic mite, Tropilaelaps mercedesae. Open Biol (2016) 0.77
Overexpression of transient receptor potential mucolipin-2 ion channels in gliomas: role in tumor growth and progression. Oncotarget (2016) 0.77
Functional role of TRP channels in modulating ER stress and Autophagy. Cell Calcium (2016) 0.77
When neurons encounter nanoobjects: spotlight on calcium signalling. Int J Environ Res Public Health (2014) 0.77
Canonical transient receptor potential channel 2 (TRPC2): old name-new games. Importance in regulating of rat thyroid cell physiology. Pflugers Arch (2014) 0.77
Nicotinamide is an endogenous agonist for a C. elegans TRPV OSM-9 and OCR-4 channel. Nat Commun (2016) 0.77
Roles of TRPM8 Ion Channels in Cancer: Proliferation, Survival, and Invasion. Cancers (Basel) (2015) 0.77
Copper-induced activation of TRP channels promotes extracellular calcium entry, activation of CaMs and CDPKs, copper entry and membrane depolarization in Ulva compressa. Front Plant Sci (2015) 0.77
Implications of Human Transient Receptor Potential Melastatin 8 (TRPM8) Channel Gating from Menthol Binding Studies of the Sensing Domain. Biochemistry (2015) 0.77
Fiber-optic control and thermometry of single-cell thermosensation logic. Sci Rep (2015) 0.77
Aberrantly Over-Expressed TRPM8 Channels in Pancreatic Adenocarcinoma: Correlation with Tumor Size/Stage and Requirement for Cancer Cells Invasion. Cells (2014) 0.76
Aberrant over-expression of TRPM7 ion channels in pancreatic cancer: required for cancer cell invasion and implicated in tumor growth and metastasis. Biol Open (2015) 0.76
Acid-sensing hypothalamic neurons controlling arousal. Cell Mol Neurobiol (2014) 0.76
Mechanical dynamics in live cells and fluorescence-based force/tension sensors. Biochim Biophys Acta (2015) 0.76
Differential evolutionary constraints in the evolution of chemoreceptors: a murine and human case study. ScientificWorldJournal (2014) 0.76
When a TRP goes bad: transient receptor potential channels in addiction. Life Sci (2012) 0.76
Effects of N-Glycosylation of the human cation channel TRPA1 on agonist-sensitivity. Biosci Rep (2016) 0.76
Overexpression of Transient Receptor Protein Cation Channel Subfamily A Member 1, Confers an Independent Prognostic Indicator in Nasopharyngeal Carcinoma. J Cancer (2016) 0.76
A novel nondevelopmental role of the sax-7/L1CAM cell adhesion molecule in synaptic regulation in Caenorhabditis elegans. Genetics (2014) 0.76
Bilaterian Giant Ankyrins Have a Common Evolutionary Origin and Play a Conserved Role in Patterning the Axon Initial Segment. PLoS Genet (2016) 0.75
Endothelin inhibits renin release from juxtaglomerular cells via endothelin receptors A and B via a transient receptor potential canonical-mediated pathway. Physiol Rep (2014) 0.75
General flexible nature of the cytosolic regions of fungal transient receptor potential (TRP) channels, revealed by expression screening using GFP-fusion techniques. Protein Sci (2014) 0.75
The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature (1997) 30.59
WWW-query: an on-line retrieval system for biological sequence banks. Biochimie (1996) 11.59
ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures. Cell (2003) 10.94
Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide. Nature (1999) 10.05
Identification of a cold receptor reveals a general role for TRP channels in thermosensation. Nature (2002) 8.94
A TRP channel that senses cold stimuli and menthol. Cell (2002) 8.66
TRP channels. Annu Rev Biochem (2007) 8.09
A mutation in the TRPC6 cation channel causes familial focal segmental glomerulosclerosis. Science (2005) 7.03
Transient receptor potential cation channels in disease. Physiol Rev (2007) 6.91
The principle of temperature-dependent gating in cold- and heat-sensitive TRP channels. Nature (2004) 5.76
TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function. Nat Genet (2005) 5.53
LTRPC7 is a Mg.ATP-regulated divalent cation channel required for cell viability. Nature (2001) 5.52
ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology. Nature (2001) 4.75
Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels. Nature (2003) 4.45
TRP-PLIK, a bifunctional protein with kinase and ion channel activities. Science (2001) 4.33
PI(4,5)P2 regulates the activation and desensitization of TRPM8 channels through the TRP domain. Nat Neurosci (2005) 4.00
Induction of vanilloid receptor channel activity by protein kinase C. Nature (2001) 3.95
Subunit composition of mammalian transient receptor potential channels in living cells. Proc Natl Acad Sci U S A (2002) 3.88
Molecular characterization of the Drosophila trp locus: a putative integral membrane protein required for phototransduction. Neuron (1989) 3.79
Impaired thermosensation in mice lacking TRPV3, a heat and camphor sensor in the skin. Science (2005) 3.63
A gain-of-function mutation in TRPA1 causes familial episodic pain syndrome. Neuron (2010) 3.31
The trp gene is essential for a light-activated Ca2+ channel in Drosophila photoreceptors. Neuron (1992) 3.19
TRPM6 forms the Mg2+ influx channel involved in intestinal and renal Mg2+ absorption. J Biol Chem (2003) 3.15
Activation of TRPV4 channels (hVRL-2/mTRP12) by phorbol derivatives. J Biol Chem (2002) 3.14
TRP channels in mechanosensation: direct or indirect activation? Nat Rev Neurosci (2007) 2.81
2-aminoethoxydiphenyl borate is a common activator of TRPV1, TRPV2, and TRPV3. J Biol Chem (2004) 2.71
International Union of Basic and Clinical Pharmacology. LXXVI. Current progress in the mammalian TRP ion channel family. Pharmacol Rev (2010) 2.66
Mutation of TRPM6 causes familial hypomagnesemia with secondary hypocalcemia. Nat Genet (2002) 2.63
Functional control of cold- and menthol-sensitive TRPM8 ion channels by phosphatidylinositol 4,5-bisphosphate. J Neurosci (2005) 2.59
Protein kinase C phosphorylation sensitizes but does not activate the capsaicin receptor transient receptor potential vanilloid 1 (TRPV1). Proc Natl Acad Sci U S A (2003) 2.58
Phosphoinositide 3-kinase binds to TRPV1 and mediates NGF-stimulated TRPV1 trafficking to the plasma membrane. J Gen Physiol (2006) 2.58
PI(3,5)P(2) controls membrane trafficking by direct activation of mucolipin Ca(2+) release channels in the endolysosome. Nat Commun (2010) 2.54
Impaired endocytosis of the ion channel TRPM4 is associated with human progressive familial heart block type I. J Clin Invest (2009) 2.54
Sensing with TRP channels. Nat Chem Biol (2005) 2.51
TRPM8 voltage sensor mutants reveal a mechanism for integrating thermal and chemical stimuli. Nat Chem Biol (2007) 2.48
Down-regulation of the novel gene melastatin correlates with potential for melanoma metastasis. Cancer Res (1998) 2.43
Mutations in TRPV4 cause Charcot-Marie-Tooth disease type 2C. Nat Genet (2009) 2.32
NompC TRP channel required for vertebrate sensory hair cell mechanotransduction. Science (2003) 2.31
Gating of TRP channels: a voltage connection? J Physiol (2005) 2.30
2-aminoethoxydiphenyl borate activates and sensitizes the heat-gated ion channel TRPV3. J Neurosci (2004) 2.27
Gain-of-function mutations in TRPV4 cause autosomal dominant brachyolmia. Nat Genet (2008) 2.24
Alterations in the ankyrin domain of TRPV4 cause congenital distal SMA, scapuloperoneal SMA and HMSN2C. Nat Genet (2009) 2.22
The Ca2+-activated cation channel TRPM4 is regulated by phosphatidylinositol 4,5-biphosphate. EMBO J (2006) 2.22
Scapuloperoneal spinal muscular atrophy and CMT2C are allelic disorders caused by alterations in TRPV4. Nat Genet (2009) 2.21
Voltage dependence of the Ca2+-activated cation channel TRPM4. J Biol Chem (2003) 2.21
Differential gene expression of TRPM1, the potential cause of congenital stationary night blindness and coat spotting patterns (LP) in the Appaloosa horse (Equus caballus). Genetics (2008) 2.15
Camphor activates and strongly desensitizes the transient receptor potential vanilloid subtype 1 channel in a vanilloid-independent mechanism. J Neurosci (2005) 2.09
Abnormal electroretinogram from a Drosophila mutant. Nature (1969) 1.97
Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitis. Proc Natl Acad Sci U S A (2010) 1.96
TRPM1 is mutated in patients with autosomal-recessive complete congenital stationary night blindness. Am J Hum Genet (2009) 1.93
Mutations in TRPM1 are a common cause of complete congenital stationary night blindness. Am J Hum Genet (2009) 1.92
Transient receptor potential channels meet phosphoinositides. EMBO J (2008) 1.89
Topical capsaicin for chronic neuropathic pain in adults. Cochrane Database Syst Rev (2009) 1.88
Internal Ca(2+) release in yeast is triggered by hypertonic shock and mediated by a TRP channel homologue. J Cell Biol (2002) 1.79
A yeast genetic screen reveals a critical role for the pore helix domain in TRP channel gating. Neuron (2008) 1.79
Melastatin expression and prognosis in cutaneous malignant melanoma. J Clin Oncol (2001) 1.75
PACSINs bind to the TRPV4 cation channel. PACSIN 3 modulates the subcellular localization of TRPV4. J Biol Chem (2006) 1.71
A primer on ankyrin repeat function in TRP channels and beyond. Mol Biosyst (2008) 1.70
Recessive mutations of the gene TRPM1 abrogate ON bipolar cell function and cause complete congenital stationary night blindness in humans. Am J Hum Genet (2009) 1.68
Transcriptional regulation of the melanoma prognostic marker melastatin (TRPM1) by MITF in melanocytes and melanoma. Cancer Res (2004) 1.64
A TRP homolog in Saccharomyces cerevisiae forms an intracellular Ca(2+)-permeable channel in the yeast vacuolar membrane. Proc Natl Acad Sci U S A (2001) 1.63
Structure of the N-terminal ankyrin repeat domain of the TRPV2 ion channel. J Biol Chem (2006) 1.57
Only six kingdoms of life. Proc Biol Sci (2004) 1.57
The role of transient receptor potential cation channels in Ca2+ signaling. Cold Spring Harb Perspect Biol (2010) 1.56
The TRPC3 channel has a large internal chamber surrounded by signal sensing antennas. J Mol Biol (2006) 1.54
Novel TRPM6 mutations in 21 families with primary hypomagnesemia and secondary hypocalcemia. J Am Soc Nephrol (2005) 1.52
Pirt, a phosphoinositide-binding protein, functions as a regulatory subunit of TRPV1. Cell (2008) 1.52
Ca2+ signalling in plants and green algae--changing channels. Trends Plant Sci (2008) 1.50
Mucolipins: Intracellular TRPML1-3 channels. FEBS Lett (2010) 1.49
Activation of the melastatin-related cation channel TRPM3 by D-erythro-sphingosine [corrected]. Mol Pharmacol (2004) 1.49
Transient receptor potential channelopathies. Pflugers Arch (2010) 1.40
Modulation of TRPs by PIPs. J Physiol (2007) 1.35
Structure-function relationship of the TRP channel superfamily. Rev Physiol Biochem Pharmacol (2006) 1.35
Effects of piperine, the pungent component of black pepper, at the human vanilloid receptor (TRPV1). Br J Pharmacol (2005) 1.33
Downregulation of transient receptor potential melastatin 8 by protein kinase C-mediated dephosphorylation. J Neurosci (2005) 1.31
Modulation of the transient receptor potential channel TRPA1 by phosphatidylinositol 4,5-biphosphate manipulators. Pflugers Arch (2008) 1.31
A-kinase anchoring protein mediates TRPV1 thermal hyperalgesia through PKA phosphorylation of TRPV1. Pain (2008) 1.31
TRP channels entering the structural era. J Physiol (2008) 1.28
TRPMLs: in sickness and in health. Am J Physiol Renal Physiol (2009) 1.26
Stimulus-specific modulation of the cation channel TRPV4 by PACSIN 3. J Biol Chem (2008) 1.26
Unicellular Ca2+ signaling 'toolkit' at the origin of metazoa. Mol Biol Evol (2008) 1.22
TRPV1 activation and induction of nociceptive response by a non-pungent capsaicin-like compound, capsiate. Neuropharmacology (2003) 1.20
TRPC6 and FSGS: the latest TRP channelopathy. Biochim Biophys Acta (2007) 1.18
TRP channels in Drosophila photoreceptor cells. J Physiol (2005) 1.16
Mucolipin 1: endocytosis and cation channel--a review. Pflugers Arch (2004) 1.16
Regulation of transient receptor potential (TRP) channels by phosphoinositides. Pflugers Arch (2007) 1.16
Yeast screens show aromatic residues at the end of the sixth helix anchor transient receptor potential channel gate. Proc Natl Acad Sci U S A (2007) 1.15
Regulation of transient receptor potential channels of melastatin type 8 (TRPM8): effect of cAMP, cannabinoid CB(1) receptors and endovanilloids. Exp Cell Res (2007) 1.14
Bisandrographolide from Andrographis paniculata activates TRPV4 channels. J Biol Chem (2006) 1.14
Yeast gain-of-function mutations reveal structure-function relationships conserved among different subfamilies of transient receptor potential channels. Proc Natl Acad Sci U S A (2007) 1.09
Analgesic potential of TRPV1 antagonists. Biochem Pharmacol (2009) 1.08
Channelopathies converge on TRPV4. Nat Genet (2010) 1.06
Association of immunophilins with mammalian TRPC channels. J Biol Chem (2004) 1.05
The taste transduction channel TRPM5 is a locus for bitter-sweet taste interactions. FASEB J (2007) 1.04
Resiniferatoxin-type phorboid vanilloids display capsaicin-like selectivity at native vanilloid receptors on rat DRG neurons and at the cloned vanilloid receptor VR1. Br J Pharmacol (1999) 1.02
Isolation of ON bipolar cell genes via hrGFP-coupled cell enrichment using the mGluR6 promoter. J Biochem (2009) 0.97
Polycystic kidney disease: hereditary and acquired. Adv Intern Med (1993) 0.96
Divide and conquer: high resolution structural information on TRP channel fragments. J Gen Physiol (2009) 0.91
Modulation of the transient receptor potential vanilloid channel TRPV4 by 4alpha-phorbol esters: a structure-activity study. J Med Chem (2009) 0.91
Transient receptor potential cation channels in disease. Physiol Rev (2007) 6.91
TRP channels: an overview. Cell Calcium (2005) 2.98
Sensing with TRP channels. Nat Chem Biol (2005) 2.51
TRPM8 voltage sensor mutants reveal a mechanism for integrating thermal and chemical stimuli. Nat Chem Biol (2007) 2.48
TRPM3 is a nociceptor channel involved in the detection of noxious heat. Neuron (2011) 2.31
Gating of TRP channels: a voltage connection? J Physiol (2005) 2.30
Gain-of-function mutations in TRPV4 cause autosomal dominant brachyolmia. Nat Genet (2008) 2.24
The Ca2+-activated cation channel TRPM4 is regulated by phosphatidylinositol 4,5-biphosphate. EMBO J (2006) 2.22
Deletion of the transient receptor potential cation channel TRPV4 impairs murine bladder voiding. J Clin Invest (2007) 2.19
The vanilloid transient receptor potential channel TRPV4: from structure to disease. Prog Biophys Mol Biol (2009) 2.13
Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitis. Proc Natl Acad Sci U S A (2010) 1.96
Transient receptor potential channels meet phosphoinositides. EMBO J (2008) 1.89
Regulation of the Ca2+ sensitivity of the nonselective cation channel TRPM4. J Biol Chem (2004) 1.82
TRPV4-mediated calcium influx regulates terminal differentiation of osteoclasts. Cell Metab (2008) 1.79
The transient receptor potential channel TRPA1: from gene to pathophysiology. Pflugers Arch (2012) 1.63
The loss and progressive recovery of voiding after spinal cord interruption in rats is associated with simultaneous changes in autonomous contractile bladder activity. Eur Urol (2008) 1.48
Loss of high-frequency glucose-induced Ca2+ oscillations in pancreatic islets correlates with impaired glucose tolerance in Trpm5-/- mice. Proc Natl Acad Sci U S A (2010) 1.46
Vanilloid transient receptor potential cation channels: an overview. Curr Pharm Des (2008) 1.40
Transient receptor potential channelopathies. Pflugers Arch (2010) 1.40
Functional characterization of transient receptor potential channels in mouse urothelial cells. Am J Physiol Renal Physiol (2009) 1.39
Determinants of 4 alpha-phorbol sensitivity in transmembrane domains 3 and 4 of the cation channel TRPV4. J Biol Chem (2007) 1.36
Irritating channels: the case of TRPA1. J Physiol (2010) 1.32
Modulation of the transient receptor potential channel TRPA1 by phosphatidylinositol 4,5-biphosphate manipulators. Pflugers Arch (2008) 1.31
Stimulus-specific modulation of the cation channel TRPV4 by PACSIN 3. J Biol Chem (2008) 1.26
The selectivity filter of the cation channel TRPM4. J Biol Chem (2005) 1.24
TRPV3: time to decipher a poorly understood family member! J Physiol (2013) 1.18
TRP channels. Compr Physiol (2012) 1.17
TRPM8-independent menthol-induced Ca2+ release from endoplasmic reticulum and Golgi. J Biol Chem (2006) 1.09
TRP channels in neurogastroenterology: opportunities for therapeutic intervention. Br J Pharmacol (2011) 1.07
Channelopathies converge on TRPV4. Nat Genet (2010) 1.06
Transcriptional activation of metalloid tolerance genes in Saccharomyces cerevisiae requires the AP-1-like proteins Yap1p and Yap8p. Mol Biol Cell (2004) 1.06
Systematic and quantitative mRNA expression analysis of TRP channel genes at the single trigeminal and dorsal root ganglion level in mouse. BMC Neurosci (2013) 1.05
Invertebrate TRP proteins as functional models for mammalian channels. Pflugers Arch (2004) 1.05
Molecular functions of anoctamin 6 (TMEM16F): a chloride channel, cation channel, or phospholipid scramblase? Pflugers Arch (2013) 1.02
HGF/SF and menthol increase human glioblastoma cell calcium and migration. Biochem Biophys Res Commun (2008) 1.00
TRPP2 and TRPV4 form an EGF-activated calcium permeable channel at the apical membrane of renal collecting duct cells. PLoS One (2013) 0.94
TRPM4 regulates migration of mast cells in mice. Cell Calcium (2008) 0.93
Modulation of the transient receptor potential vanilloid channel TRPV4 by 4alpha-phorbol esters: a structure-activity study. J Med Chem (2009) 0.91
Mechanisms of transient receptor potential vanilloid 1 activation and sensitization by allyl isothiocyanate. Mol Pharmacol (2013) 0.91
TRPC channels are involved in calcium-dependent migration and proliferation in immortalized GnRH neurons. Cell Calcium (2011) 0.87
Functional analysis of CFTR chloride channel activity in cells with elevated MDR1 expression. Biochem Biophys Res Commun (2003) 0.84
Interaction of the protein phosphatase 2A with the regulatory domain of the cystic fibrosis transmembrane conductance regulator channel. FEBS Lett (2005) 0.81
Chronic exposure to EGF affects trafficking and function of ENaC channel in cystic fibrosis cells. Biochem Biophys Res Commun (2005) 0.80
Activation of TRPV4 channels reduces migration of immortalized neuroendocrine cells. J Neurochem (2011) 0.79
Insulin downregulates the expression of the Ca2+-activated nonselective cation channel TRPM5 in pancreatic islets from leptin-deficient mouse models. Pflugers Arch (2013) 0.77
Silencing SERCA1b in a few fibers stimulates growth in the entire regenerating soleus muscle. Histochem Cell Biol (2010) 0.76
Maturation of stretch-induced contractile activity and its muscarinic regulation in isolated whole bladder strips from rat. Neurourol Urodyn (2010) 0.75