Published in J Immunol on November 15, 2008
Multifarious roles of sialic acids in immunity. Ann N Y Acad Sci (2012) 2.09
Molecular mechanism underlying sialic acid as an essential nutrient for brain development and cognition. Adv Nutr (2012) 1.19
Structural and functional impairments of polysialic acid by a mutated polysialyltransferase found in schizophrenia. J Biol Chem (2011) 1.07
Novel regulation of fibroblast growth factor 2 (FGF2)-mediated cell growth by polysialic acid. J Biol Chem (2011) 0.99
Polysialic acid governs T-cell development by regulating progenitor access to the thymus. Proc Natl Acad Sci U S A (2009) 0.94
Encore: Genetic Association Interaction Network centrality pipeline and application to SLE exome data. Genet Epidemiol (2013) 0.92
Polysialylation controls dendritic cell trafficking by regulating chemokine recognition. Science (2015) 0.92
Sialic acid metabolism and sialyltransferases: natural functions and applications. Appl Microbiol Biotechnol (2012) 0.91
Clonal analysis reveals uniformity in the molecular profile and lineage potential of CCR9(+) and CCR9(-) thymus-settling progenitors. J Immunol (2011) 0.85
Crossroads between Bacterial and Mammalian Glycosyltransferases. Front Immunol (2014) 0.84
The Prion Protein Controls Polysialylation of Neural Cell Adhesion Molecule 1 during Cellular Morphogenesis. PLoS One (2015) 0.83
Bacteriophages and phage-derived proteins--application approaches. Curr Med Chem (2015) 0.83
A new sialidase mechanism: bacteriophage K1F endo-sialidase is an inverting glycosidase. J Biol Chem (2009) 0.82
Polysialic acid enhances the migration and invasion of human cytotrophoblasts. Glycobiology (2012) 0.82
High expression of β3GnT8 is associated with the metastatic potential of human glioma. Int J Mol Med (2014) 0.81
Polysialic acid is present in mammalian semen as a post-translational modification of the neural cell adhesion molecule NCAM and the polysialyltransferase ST8SiaII. J Biol Chem (2013) 0.81
Capsular polysaccharide vaccine for Group B Neisseria meningitidis, Escherichia coli K1, and Pasteurella haemolytica A2. Proc Natl Acad Sci U S A (2011) 0.81
Sugar-coated sperm: Unraveling the functions of the mammalian sperm glycocalyx. Mol Reprod Dev (2015) 0.81
Sequences from the first fibronectin type III repeat of the neural cell adhesion molecule allow O-glycan polysialylation of an adhesion molecule chimera. J Biol Chem (2010) 0.81
Crystal structure of anti-polysialic acid antibody single chain Fv fragment complexed with octasialic acid: insight into the binding preference for polysialic acid. J Biol Chem (2013) 0.80
Changes in polysialic acid expression on myeloid cells during differentiation and recruitment to sites of inflammation: role in phagocytosis. Glycobiology (2014) 0.80
NCAM1 Polysialylation: The Prion Protein's Elusive Reason for Being? ASN Neuro (2016) 0.77
Polysialic acid expression is not necessary for motor neuron target selectivity. Muscle Nerve (2012) 0.77
Polysialylation of NCAM characterizes the proliferation period of contractile elements during postnatal development of the epididymis. PLoS One (2015) 0.77
The DC-SIGN-CD56 interaction inhibits the anti-dendritic cell cytotoxicity of CD56 expressing cells. Infect Agent Cancer (2015) 0.75
Expression of neural cell adhesion molecule and polysialic acid in human bone marrow-derived mesenchymal stromal cells. Stem Cell Res Ther (2016) 0.75
Molecular characterization and expression analyses of ST8Sia II and IV in piglets during postnatal development: lack of correlation between transcription and posttranslational levels. Glycoconj J (2015) 0.75
Developmental changes in the level of free and conjugated sialic acids, Neu5Ac, Neu5Gc and KDN in different organs of pig: a LC-MS/MS quantitative analyses. Glycoconj J (2016) 0.75
An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database. J Am Soc Mass Spectrom (1994) 45.51
Peptide antimicrobial agents. Clin Microbiol Rev (2006) 6.04
Mammalian defensins in immunity: more than just microbicidal. Trends Immunol (2002) 3.52
In vivo effects of anti-asialo GM1. I. Reduction of NK activity and enhancement of transplanted tumor growth in nude mice. J Immunol (1981) 3.34
The inflammatory response to cell death. Annu Rev Pathol (2008) 2.85
NZB mouse system for production of monoclonal antibodies to weak bacterial antigens: isolation of an IgG antibody to the polysaccharide capsules of Escherichia coli K1 and group B meningococci. Proc Natl Acad Sci U S A (1985) 2.49
Identification of CRAMP, a cathelin-related antimicrobial peptide expressed in the embryonic and adult mouse. J Biol Chem (1997) 2.38
Identity of Leu-19 (CD56) leukocyte differentiation antigen and neural cell adhesion molecule. J Exp Med (1989) 2.17
Direct bacterial protein PAMP recognition by human NK cells involves TLRs and triggers alpha-defensin production. Blood (2004) 1.71
Interactions among colony-stimulating factors, IL-1 beta, IL-6, and kit-ligand in the regulation of primitive murine hematopoietic cells. Exp Hematol (1992) 1.56
Macrophages and neutrophils are the targets for immune suppression by glucocorticoids in contact allergy. J Clin Invest (2007) 1.51
Polysialic acid in human milk. CD36 is a new member of mammalian polysialic acid-containing glycoprotein. J Biol Chem (2003) 1.41
Polysialylated neuropilin-2 is expressed on the surface of human dendritic cells and modulates dendritic cell-T lymphocyte interactions. J Biol Chem (2007) 1.39
Prevention and cure of systemic Escherichia coli K1 infection by modification of the bacterial phenotype. Antimicrob Agents Chemother (2004) 1.38
Polysialic acid is associated with sodium channels and the neural cell adhesion molecule N-CAM in adult rat brain. J Biol Chem (1992) 1.27
Mice deficient in the polysialyltransferase ST8SiaIV/PST-1 allow discrimination of the roles of neural cell adhesion molecule protein and polysialic acid in neural development and synaptic plasticity. J Neurosci (2000) 1.26
Antibodies to poly[(2----8)-alpha-N-acetylneuraminic acid] and poly[(2----9)-alpha-N-acetylneuraminic acid] are elicited by immunization of mice with Escherichia coli K92 conjugates: potential vaccines for groups B and C meningococci and E. coli K1. Proc Natl Acad Sci U S A (1991) 1.22
Human placental cytotrophoblasts attract monocytes and CD56(bright) natural killer cells via the actions of monocyte inflammatory protein 1alpha. J Exp Med (2001) 1.16
Sialyltransferase ST8Sia-II assembles a subset of polysialic acid that directs hippocampal axonal targeting and promotes fear behavior. J Biol Chem (2004) 1.16
Polysialic acid facilitates tumor invasion by glioma cells. Glycobiology (2005) 1.13
A role for the polysialic acid-neural cell adhesion molecule in PDGF-induced chemotaxis of oligodendrocyte precursor cells. J Cell Sci (2003) 1.10
Antimicrobial peptides derived from growth factors. Growth Factors (2007) 1.09
PSA-NCAM modulates BDNF-dependent survival and differentiation of cortical neurons. Eur J Neurosci (2001) 1.08
Degree of polymerization (DP) of polysialic acid (polySia) on neural cell adhesion molecules (N-CAMS): development and application of a new strategy to accurately determine the DP of polySia chains on N-CAMS. J Biol Chem (2005) 1.05
In vitro systems for the study of T cell development: fetal thymus organ culture and OP9-DL1 cell coculture. Curr Protoc Immunol (2006) 0.99
Polysialic acid regulates cell contact-dependent neuronal differentiation of progenitor cells from the subventricular zone. Dev Dyn (2004) 0.97
Localization and characterization of polysialic acid-containing N-linked glycans from bovine NCAM. Glycobiology (2002) 0.97
Expression of neural cell adhesion molecules (polysialylated form of neural cell adhesion molecule and L1-cell adhesion molecule) on resected small cell lung cancer specimens: in relation to proliferation state. J Surg Oncol (2001) 0.95
Fetal bone marrow as a source of stem cells for in utero or postnatal transplantation. Br J Haematol (2000) 0.88
Defensins and cathelicidins: neutrophil peptides with roles in inflammation, hyperlipidemia and atherosclerosis. J Cell Mol Med (2005) 0.88
Monoclonal antibodies to polysialic acid reveal epitope sharing between invasive pathogenic bacteria, differentiating cells and tumor cells. Immunol Res (1987) 0.84
Developmental profile of neural cell adhesion molecule glycoforms with a varying degree of polymerization of polysialic acid chains. J Biol Chem (2001) 0.83
Dynamic change of neural cell adhesion molecule polysialylation on human neuroblastoma (IMR-32) and rat pheochromocytoma (PC-12) cells during growth and differentiation. J Biol Chem (2002) 0.83
Disparate regulation of human fetal erythropoiesis by the microenvironments of the liver and bone marrow. Blood Cells Mol Dis (2001) 0.82
Enzymatic removal of polysialic acid from neural cell adhesion molecule perturbs the migration route of luteinizing hormone-releasing hormone neurons in the developing chick forebrain. J Comp Neurol (2000) 0.81
Impact of polysialylated CD56 on natural killer cell cytotoxicity. BMC Immunol (2007) 0.80
Embryonic neural cell adhesion molecules on human natural killer cells. Eur J Immunol (1989) 0.79
Interference with O-glycosylation in RMA lymphoma cells leads to a reduced in vivo growth of the tumor. Int J Cancer (2006) 0.78
Copper-free click chemistry for dynamic in vivo imaging. Proc Natl Acad Sci U S A (2007) 8.50
Bioorthogonal chemistry: fishing for selectivity in a sea of functionality. Angew Chem Int Ed Engl (2009) 8.15
Chemistry in living systems. Nat Chem Biol (2005) 7.55
A strain-promoted [3 + 2] azide-alkyne cycloaddition for covalent modification of biomolecules in living systems. J Am Chem Soc (2004) 7.51
Glycans in cancer and inflammation--potential for therapeutics and diagnostics. Nat Rev Drug Discov (2005) 6.14
Maternal alloantigens promote the development of tolerogenic fetal regulatory T cells in utero. Science (2008) 5.76
In vivo imaging of membrane-associated glycans in developing zebrafish. Science (2008) 5.45
Incorporation of azides into recombinant proteins for chemoselective modification by the Staudinger ligation. Proc Natl Acad Sci U S A (2001) 4.88
Chemical remodelling of cell surfaces in living animals. Nature (2004) 4.86
A comparative study of bioorthogonal reactions with azides. ACS Chem Biol (2006) 4.26
Cu-free click cycloaddition reactions in chemical biology. Chem Soc Rev (2010) 3.89
Second-generation difluorinated cyclooctynes for copper-free click chemistry. J Am Chem Soc (2008) 3.65
Redirecting lipoic acid ligase for cell surface protein labeling with small-molecule probes. Nat Biotechnol (2007) 3.41
A chemical approach for identifying O-GlcNAc-modified proteins in cells. Proc Natl Acad Sci U S A (2003) 2.97
Copper-free click chemistry in living animals. Proc Natl Acad Sci U S A (2010) 2.76
Rapid Cu-free click chemistry with readily synthesized biarylazacyclooctynones. J Am Chem Soc (2010) 2.74
Introducing genetically encoded aldehydes into proteins. Nat Chem Biol (2007) 2.65
MmpL8 is required for sulfolipid-1 biosynthesis and Mycobacterium tuberculosis virulence. Proc Natl Acad Sci U S A (2003) 2.62
Imaging the glycome. Proc Natl Acad Sci U S A (2008) 2.62
A metabolic labeling approach toward proteomic analysis of mucin-type O-linked glycosylation. Proc Natl Acad Sci U S A (2003) 2.56
Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma. Nat Genet (2003) 2.55
From mechanism to mouse: a tale of two bioorthogonal reactions. Acc Chem Res (2011) 2.50
The glycosylphosphatidylinositol anchor: a complex membrane-anchoring structure for proteins. Biochemistry (2008) 2.40
A syndrome with congenital neutropenia and mutations in G6PC3. N Engl J Med (2009) 2.30
Investigating cellular metabolism of synthetic azidosugars with the Staudinger ligation. J Am Chem Soc (2002) 2.26
Identification, function and structure of the mycobacterial sulfotransferase that initiates sulfolipid-1 biosynthesis. Nat Struct Mol Biol (2004) 2.25
Discovery of aminoacyl-tRNA synthetase activity through cell-surface display of noncanonical amino acids. Proc Natl Acad Sci U S A (2006) 2.23
Mechanistic investigation of the staudinger ligation. J Am Chem Soc (2005) 2.19
Chemical technologies for probing glycans. Cell (2006) 2.04
Age-dependent hepatic lymphoid organization directs successful immunity to hepatitis B. J Clin Invest (2013) 2.04
A cell nanoinjector based on carbon nanotubes. Proc Natl Acad Sci U S A (2007) 2.00
Lipidomics reveals control of Mycobacterium tuberculosis virulence lipids via metabolic coupling. Proc Natl Acad Sci U S A (2007) 1.98
Metabolic labeling of glycans with azido sugars for visualization and glycoproteomics. Methods Enzymol (2006) 1.93
Probing mucin-type O-linked glycosylation in living animals. Proc Natl Acad Sci U S A (2006) 1.85
A hydrophilic azacyclooctyne for Cu-free click chemistry. Org Lett (2008) 1.84
Site-specific chemical modification of recombinant proteins produced in mammalian cells by using the genetically encoded aldehyde tag. Proc Natl Acad Sci U S A (2009) 1.83
Programmed assembly of 3-dimensional microtissues with defined cellular connectivity. Proc Natl Acad Sci U S A (2009) 1.83
Cholesterol catabolism by Mycobacterium tuberculosis requires transcriptional and metabolic adaptations. Chem Biol (2012) 1.79
A FRET-based fluorogenic phosphine for live-cell imaging with the Staudinger ligation. Angew Chem Int Ed Engl (2008) 1.79
The chemistry and biology of mucin-type O-linked glycosylation. Bioorg Med Chem (2005) 1.78
Deconvoluting the functions of polypeptide N-alpha-acetylgalactosaminyltransferase family members by glycopeptide substrate profiling. Chem Biol (2004) 1.78
Visualizing enveloping layer glycans during zebrafish early embryogenesis. Proc Natl Acad Sci U S A (2010) 1.74
Sulfotransferases and sulfatases in mycobacteria. Chem Biol (2002) 1.74
Integrated microfluidic bioprocessor for single-cell gene expression analysis. Proc Natl Acad Sci U S A (2008) 1.73
Metabolic labeling of glycans with azido sugars and subsequent glycan-profiling and visualization via Staudinger ligation. Nat Protoc (2007) 1.73
Photoaffinity isolation and identification of proteins in cancer cell extracts that bind to platinum-modified DNA. Chembiochem (2009) 1.71
High-affinity ligand probes of CD22 overcome the threshold set by cis ligands to allow for binding, endocytosis, and killing of B cells. J Immunol (2006) 1.65
Imaging cell surface glycans with bioorthogonal chemical reporters. J Am Chem Soc (2007) 1.65
Separating the contribution of glucocorticoids and wakefulness to the molecular and electrophysiological correlates of sleep homeostasis. Sleep (2010) 1.64
In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter. Proc Natl Acad Sci U S A (2010) 1.63
Genetic ablation of polysialic acid causes severe neurodevelopmental defects rescued by deletion of the neural cell adhesion molecule. J Biol Chem (2005) 1.62
Metabolic cross-talk allows labeling of O-linked beta-N-acetylglucosamine-modified proteins via the N-acetylgalactosamine salvage pathway. Proc Natl Acad Sci U S A (2011) 1.61
Evolution of bacteriophages infecting encapsulated bacteria: lessons from Escherichia coli K1-specific phages. Mol Microbiol (2006) 1.60
5'-Adenosinephosphosulphate reductase (CysH) protects Mycobacterium tuberculosis against free radicals during chronic infection phase in mice. Mol Microbiol (2006) 1.59
Site-specific antibody-drug conjugates: the nexus of bioorthogonal chemistry, protein engineering, and drug development. Bioconjug Chem (2015) 1.58
Symbol nomenclature for glycan representation. Proteomics (2009) 1.56
Identification of palmitoylated mitochondrial proteins using a bio-orthogonal azido-palmitate analogue. FASEB J (2007) 1.55
Sulfate metabolism in mycobacteria. Chembiochem (2006) 1.55
Metabolic labeling of sialic acids in living animals with alkynyl sugars. Angew Chem Int Ed Engl (2009) 1.53
Copper-free click chemistry for the in situ crosslinking of photodegradable star polymers. Chem Commun (Camb) (2008) 1.52
The structures of bacteriophages K1E and K1-5 explain processive degradation of polysaccharide capsules and evolution of new host specificities. J Mol Biol (2007) 1.48
In vivo imaging of Caenorhabditis elegans glycans. ACS Chem Biol (2009) 1.48
Deficits in sialylation impair podocyte maturation. J Am Soc Nephrol (2012) 1.47
Bringing chemistry to life. Nat Methods (2011) 1.45
Trehalose is required for growth of Mycobacterium smegmatis. J Biol Chem (2004) 1.44
Substrate recognition, protein dynamics, and iron-sulfur cluster in Pseudomonas aeruginosa adenosine 5'-phosphosulfate reductase. J Mol Biol (2006) 1.42
Noncovalent cell surface engineering: incorporation of bioactive synthetic glycopolymers into cellular membranes. J Am Chem Soc (2008) 1.41
Metabolic oligosaccharide engineering as a tool for glycobiology. Curr Opin Chem Biol (2003) 1.41
Site-specific chemical protein conjugation using genetically encoded aldehyde tags. Nat Protoc (2012) 1.40
Searching for common stem cells of the hepatic and hematopoietic systems in the human fetal liver: CD34+ cytokeratin 7/8+ cells express markers for stellate cells. J Hepatol (2004) 1.40
Polysialylated neuropilin-2 is expressed on the surface of human dendritic cells and modulates dendritic cell-T lymphocyte interactions. J Biol Chem (2007) 1.39
Programmable cell adhesion encoded by DNA hybridization. Angew Chem Int Ed Engl (2006) 1.39
Selective enrichment of azide-containing peptides from complex mixtures. J Proteome Res (2009) 1.38
Crystal structure of the polysialic acid-degrading endosialidase of bacteriophage K1F. Nat Struct Mol Biol (2004) 1.36
A chemical reporter strategy to probe glycoprotein fucosylation. J Am Chem Soc (2006) 1.35
Compositional profiling of heparin/heparan sulfate using mass spectrometry: assay for specificity of a novel extracellular human endosulfatase. Glycobiology (2005) 1.35
Function and structure of a prokaryotic formylglycine-generating enzyme. J Biol Chem (2008) 1.35
A conserved mechanism for sulfonucleotide reduction. PLoS Biol (2005) 1.34
Membrane proteomics of phagosomes suggests a connection to autophagy. Proc Natl Acad Sci U S A (2008) 1.34
Chemical approaches to perturb, profile, and perceive glycans. Acc Chem Res (2009) 1.33
A decade of bioorthogonal chemistry. Acc Chem Res (2011) 1.32
Sialic acids in the brain: gangliosides and polysialic acid in nervous system development, stability, disease, and regeneration. Physiol Rev (2014) 1.32
Boron nitride nanotubes are noncytotoxic and can be functionalized for interaction with proteins and cells. J Am Chem Soc (2009) 1.31
Rapid detection, discovery, and identification of post-translationally myristoylated proteins during apoptosis using a bio-orthogonal azidomyristate analog. FASEB J (2007) 1.31
Direct cell surface modification with DNA for the capture of primary cells and the investigation of myotube formation on defined patterns. Langmuir (2009) 1.30
Synaptic cell adhesion molecule SynCAM 1 is a target for polysialylation in postnatal mouse brain. Proc Natl Acad Sci U S A (2010) 1.30
(D)-Amino acid chemical reporters reveal peptidoglycan dynamics of an intracellular pathogen. ACS Chem Biol (2013) 1.29
Difluorobenzocyclooctyne: synthesis, reactivity, and stabilization by beta-cyclodextrin. J Am Chem Soc (2010) 1.29
Mycobacterium tuberculosis strains disrupted in mce3 and mce4 operons are attenuated in mice. J Med Microbiol (2008) 1.29
Synthetic riboswitches that induce gene expression in diverse bacterial species. Appl Environ Microbiol (2010) 1.29
A fluorogenic dye activated by the staudinger ligation. J Am Chem Soc (2003) 1.29
Expanding the diversity of unnatural cell-surface sialic acids. Chembiochem (2004) 1.29
5'-adenosinephosphosulfate lies at a metabolic branch point in mycobacteria. J Biol Chem (2002) 1.27
Discovery of sulfated metabolites in mycobacteria with a genetic and mass spectrometric approach. Proc Natl Acad Sci U S A (2002) 1.26
Metabolic labeling of fucosylated glycans in developing zebrafish. ACS Chem Biol (2011) 1.25
Synthesis of heterobifunctional protein fusions using copper-free click chemistry and the aldehyde tag. Angew Chem Int Ed Engl (2012) 1.25
PapA1 and PapA2 are acyltransferases essential for the biosynthesis of the Mycobacterium tuberculosis virulence factor sulfolipid-1. Proc Natl Acad Sci U S A (2007) 1.25